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The map label for this gene is fbp [H]

Identifier: 218930534

GI number: 218930534

Start: 3929152

End: 3930165

Strand: Direct

Name: fbp [H]

Synonym: YPO3520

Alternate gene names: 218930534

Gene position: 3929152-3930165 (Clockwise)

Preceding gene: 218930532

Following gene: 218930535

Centisome position: 84.43

GC content: 46.45

Gene sequence:

>1014_bases
ATGAAAACGTTAGGCGAATTCATCGTCGAGAAACAGCTCGATTTCTCTCACGCCACTGGCGAACTAACTGCGTTACTTTC
AGCAATCAAACTCGGCGCAAAGATCATTCACCGCGATATCAACAAAGCAGGTCTGGTTGATATCTTAGGTGCCAGCGGCG
TTTCCAATATTCAGGGCGAGGACCAGATGAAACTGGATCTGTTTGCCAATGAAAAGTTGAAAGCTGCCCTTAAAGCCCGT
GGTGAAGTTGCCGGTATAGCCTCCGAAGAAGAAGATGACATTGTCATTTTTGATGGCGGAAGAGCAGAAAATGCCAAGTA
TGTGGTTTTGATGGATCCACTGGATGGTTCTTCAAATATTGATGTGAATGTTTCTGTTGGCACAATTTTCTCAATTTATC
GTCGTATTACGCCATTTGGGACACCAATCACTGAAGAAGACTTCCTGCAACCGGGTACCAAACAAGTCACGGCAGGCTAT
GTCGTTTACGGTTCCTCAACCATGTTGGTCTATACCACAGGTTACGGTGTCCATGCCTTTACCTACGATCCTTCTCTGGG
TGTTTTCTGTTTATCCCACGAAAAAGTTCGCTATCCCGCAACCGGTTGCATGTATTCCATCAACGAAGGGAATTACATTA
AATTCCCTCTGGGTGTGAAAAAATACATCAAGTATTGCCAGGAGCAAGACGAAGCCACTAAGCGCCCATATACCTCCCGT
TATATTGGTTCATTAGTTGCTGATTTTCATCGTAACCTGTTGAAGGGCGGTATTTATATTTACCCAAGTACCGCCAGCCA
CCCTCAAGGGAAACTGCGTTTGTTGTATGAGTGCAACCCAATGGCCTTCCTCGCGGAGCAAGCCGGTGGTAAAGCCACCG
ATGGGGTGAACCGTATTCTGGACATCGTGCCAGAGAAACTGCATCAACGCGCACCGTTCTTCGTGGGAACAAAATCCATG
GTGGAAGATGCGGAAGGGTTTATCGCTAAATTCCCAGATGAAGAAGCCAAGTAA

Upstream 100 bases:

>100_bases
ATTGCCTATGAATCAATCTTACCTTTGGGCTACACTGCTGACATTAGCTGTGTTGTGTATTAATAAATCGATATTTAACC
GTAGATTCAGGGATTGTGTC

Downstream 100 bases:

>100_bases
CTTGCAGTAATGCCGTCGCTCCCTTCAAAAATAAGCTAACAGCGGCCTTTTAAGCCGCTGTTTTTTATTTCTAACGGAAT
AAAATAGCCCTACCTCTGGC

Product: fructose-1,6-bisphosphatase

Products: NA

Alternate protein names: FBPase class 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 [H]

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MKTLGEFIVEKQLDFSHATGELTALLSAIKLGAKIIHRDINKAGLVDILGASGVSNIQGEDQMKLDLFANEKLKAALKAR
GEVAGIASEEEDDIVIFDGGRAENAKYVVLMDPLDGSSNIDVNVSVGTIFSIYRRITPFGTPITEEDFLQPGTKQVTAGY
VVYGSSTMLVYTTGYGVHAFTYDPSLGVFCLSHEKVRYPATGCMYSINEGNYIKFPLGVKKYIKYCQEQDEATKRPYTSR
YIGSLVADFHRNLLKGGIYIYPSTASHPQGKLRLLYECNPMAFLAEQAGGKATDGVNRILDIVPEKLHQRAPFFVGTKSM
VEDAEGFIAKFPDEEAK

Sequences:

>Translated_337_residues
MKTLGEFIVEKQLDFSHATGELTALLSAIKLGAKIIHRDINKAGLVDILGASGVSNIQGEDQMKLDLFANEKLKAALKAR
GEVAGIASEEEDDIVIFDGGRAENAKYVVLMDPLDGSSNIDVNVSVGTIFSIYRRITPFGTPITEEDFLQPGTKQVTAGY
VVYGSSTMLVYTTGYGVHAFTYDPSLGVFCLSHEKVRYPATGCMYSINEGNYIKFPLGVKKYIKYCQEQDEATKRPYTSR
YIGSLVADFHRNLLKGGIYIYPSTASHPQGKLRLLYECNPMAFLAEQAGGKATDGVNRILDIVPEKLHQRAPFFVGTKSM
VEDAEGFIAKFPDEEAK
>Mature_337_residues
MKTLGEFIVEKQLDFSHATGELTALLSAIKLGAKIIHRDINKAGLVDILGASGVSNIQGEDQMKLDLFANEKLKAALKAR
GEVAGIASEEEDDIVIFDGGRAENAKYVVLMDPLDGSSNIDVNVSVGTIFSIYRRITPFGTPITEEDFLQPGTKQVTAGY
VVYGSSTMLVYTTGYGVHAFTYDPSLGVFCLSHEKVRYPATGCMYSINEGNYIKFPLGVKKYIKYCQEQDEATKRPYTSR
YIGSLVADFHRNLLKGGIYIYPSTASHPQGKLRLLYECNPMAFLAEQAGGKATDGVNRILDIVPEKLHQRAPFFVGTKSM
VEDAEGFIAKFPDEEAK

Specific function: INVOLVED IN SEVERAL METABOLIC PATHWAYS. IN E.COLI AND YEAST IT IS NECESSARY FOR GROWTH ON SUBSTANCES SUCH AS GLYCEROL, SUCCINATE AND ACETATE. [C]

COG id: COG0158

COG function: function code G; Fructose-1,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 1 family [H]

Homologues:

Organism=Homo sapiens, GI189083692, Length=317, Percent_Identity=43.217665615142, Blast_Score=249, Evalue=2e-66,
Organism=Homo sapiens, GI16579888, Length=317, Percent_Identity=43.217665615142, Blast_Score=249, Evalue=2e-66,
Organism=Homo sapiens, GI22907028, Length=323, Percent_Identity=42.4148606811146, Blast_Score=247, Evalue=9e-66,
Organism=Escherichia coli, GI1790679, Length=333, Percent_Identity=84.0840840840841, Blast_Score=575, Evalue=1e-165,
Organism=Caenorhabditis elegans, GI17508131, Length=331, Percent_Identity=46.5256797583082, Blast_Score=300, Evalue=9e-82,
Organism=Saccharomyces cerevisiae, GI6323409, Length=337, Percent_Identity=43.026706231454, Blast_Score=266, Evalue=4e-72,
Organism=Drosophila melanogaster, GI45550998, Length=326, Percent_Identity=46.9325153374233, Blast_Score=284, Evalue=5e-77,
Organism=Drosophila melanogaster, GI19921562, Length=326, Percent_Identity=46.9325153374233, Blast_Score=284, Evalue=7e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000146
- InterPro:   IPR020548 [H]

Pfam domain/function: PF00316 FBPase [H]

EC number: =3.1.3.11 [H]

Molecular weight: Translated: 36997; Mature: 36997

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS00124 FBPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLGEFIVEKQLDFSHATGELTALLSAIKLGAKIIHRDINKAGLVDILGASGVSNIQGE
CCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCC
DQMKLDLFANEKLKAALKARGEVAGIASEEEDDIVIFDGGRAENAKYVVLMDPLDGSSNI
CCEEEEEECCHHHHHHHHHCCCEEECCCCCCCCEEEEECCCCCCCEEEEEECCCCCCCCE
DVNVSVGTIFSIYRRITPFGTPITEEDFLQPGTKQVTAGYVVYGSSTMLVYTTGYGVHAF
EEEEEHHHHHHHHHHHCCCCCCCCHHHHCCCCCCEEEEEEEEECCCEEEEEEECCCEEEE
TYDPSLGVFCLSHEKVRYPATGCMYSINEGNYIKFPLGVKKYIKYCQEQDEATKRPYTSR
EECCCCCEEEECCCCEECCCCCEEEEECCCCEEEECCCHHHHHHHHHHHHHHHCCCCHHH
YIGSLVADFHRNLLKGGIYIYPSTASHPQGKLRLLYECNPMAFLAEQAGGKATDGVNRIL
HHHHHHHHHHHHHHHCCEEEECCCCCCCCCCEEEEEECCCHHHHHHHCCCCCCHHHHHHH
DIVPEKLHQRAPFFVGTKSMVEDAEGFIAKFPDEEAK
HHHHHHHHHCCCEEEECHHHHHHHCCCEEECCCCCCC
>Mature Secondary Structure
MKTLGEFIVEKQLDFSHATGELTALLSAIKLGAKIIHRDINKAGLVDILGASGVSNIQGE
CCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCC
DQMKLDLFANEKLKAALKARGEVAGIASEEEDDIVIFDGGRAENAKYVVLMDPLDGSSNI
CCEEEEEECCHHHHHHHHHCCCEEECCCCCCCCEEEEECCCCCCCEEEEEECCCCCCCCE
DVNVSVGTIFSIYRRITPFGTPITEEDFLQPGTKQVTAGYVVYGSSTMLVYTTGYGVHAF
EEEEEHHHHHHHHHHHCCCCCCCCHHHHCCCCCCEEEEEEEEECCCEEEEEEECCCEEEE
TYDPSLGVFCLSHEKVRYPATGCMYSINEGNYIKFPLGVKKYIKYCQEQDEATKRPYTSR
EECCCCCEEEECCCCEECCCCCEEEEECCCCEEEECCCHHHHHHHHHHHHHHHCCCCHHH
YIGSLVADFHRNLLKGGIYIYPSTASHPQGKLRLLYECNPMAFLAEQAGGKATDGVNRIL
HHHHHHHHHHHHHHHCCEEEECCCCCCCCCCEEEEEECCCHHHHHHHCCCCCCHHHHHHH
DIVPEKLHQRAPFFVGTKSMVEDAEGFIAKFPDEEAK
HHHHHHHHHCCCEEEECHHHHHHHCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA