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The map label for this gene is pssA [H]

Identifier: 218930298

GI number: 218930298

Start: 3646828

End: 3648186

Strand: Direct

Name: pssA [H]

Synonym: YPO3273

Alternate gene names: 218930298

Gene position: 3646828-3648186 (Clockwise)

Preceding gene: 218930297

Following gene: 218930299

Centisome position: 78.36

GC content: 46.65

Gene sequence:

>1359_bases
GTGATGTTGTCAAAATTCAAACGTAGCAAACATCAACAACACCTTGCACAACTGCCCAAACTCCCCCAGTCAGTTGATGA
TGTCCAAACGCTTTATTGCCCCAAGGTTTTCCGCTCTACTCTGTTGGAACTCATCGCTCAGGCAACCAAACGTATTTTTC
TGGTGGCACTTTATCTGGAGCAGGATGACGCAGGCCGTGATGTAATGAATGCCCTCTATCAGGCCAAGCAGTCGCATCCT
GAACTGGAGATCTATGTACTGGTAGATTGGCACCGGGCTCAGCGTGGCCGTATTGGTGCGGCAGCCGTCAATACTAATGC
CGATTGGTATTGCGATATGGCGGCTAAACATCCAAATATTTCTGTTCCTGTTTACGGTGTCCCGGTCAATACGCGTGAAG
CATTGGGTGTACTGCACCTAAAAGGCTTTATCATTGACGACACCGTTATTTATAGCGGTGCCAGCATCAATGATGTCTAT
CTCTATCAGAATGATAAATATCGTTATGATCGCTACCAGCTAATCACTAATCCGTCACTCGCTACCATTATGGTTGATTA
CGTGAAACAACGGATACTGAGTGCCGGAGCAGTTCAACGCCTTGACCGTAATGACCGACCTACCACCCCCGAGATCAAGA
ATGAGACCCGCCAGTTTCGCTCATCACTGCGTGATGCCAGTTACCAATTCTCGGCACAAGCGCATAACGATGAGTTAGCG
GTCACTCCTCTGGTTGGGTTAGGTAAGAAGAGTTTACTAAACAAAACGATTCATCACTTAATGGCCTCCGCTGATGAACG
CCTGACCATTTGCACCCCCTACTTTAACCTGCCCGCGCTGTTAGTCCGTAATATTATTTATCTGCTGCGGGAAGGTAAGC
AGGTTGAGATTATCGTTGGTGATAAAACCGCAAATGACTTTTATATCCCTGAAGATCAACCCTTTAAAATTATCGGTGCA
CTGCCGTATTTATACGAAATCAACCTGCGTCGTTTCCTGAGCCGCTTACAACCGTATGTTGATAACGGGCAGCTCATTGC
TCGCTTATGGAAAGATGGCGACAACACCTATCATTTGAAAGGGATGTGGGTAGATAACAATTGGCAGTTGATCACGGGCA
ATAACCTAAACCCGCGCGCATGGCGCTTGGATTTGGAGAATGCCATTTTGATCCACGATCCTAAGCATGAAATGCATGAA
CAGCGGGCCAAAGAACTGGAGTGTATCCGCACTCATACCAAAGTGGTTTCACACTACCTTGAACTGGAGAATATCCAACA
ATATCCGGTTAAAGTTCGCAAACTTATCCGCCGTTTGCGCAGGATCCGCATTGATCGGTTAATTAGCCGTATTCTATAA

Upstream 100 bases:

>100_bases
GCACAATCCAGAAAAGTAATGGTATTATCGCCGACTCTATGGATTAGTGTTTTTTTGATATGGCGGTTTTGCCATTAAAT
AACAAGAGAAGAAGCGCACT

Downstream 100 bases:

>100_bases
GTCTTAAAGATAAAACCCGGTGAATTAGCGGGTTTTCATCTCCCACTAAAAGAGAAACTCTATGCGGCTGCATATCTATC
TTCGCCGATTGCTTATCGCC

Product: phosphatidylserine synthase

Products: NA

Alternate protein names: Phosphatidylserine synthase [H]

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MMLSKFKRSKHQQHLAQLPKLPQSVDDVQTLYCPKVFRSTLLELIAQATKRIFLVALYLEQDDAGRDVMNALYQAKQSHP
ELEIYVLVDWHRAQRGRIGAAAVNTNADWYCDMAAKHPNISVPVYGVPVNTREALGVLHLKGFIIDDTVIYSGASINDVY
LYQNDKYRYDRYQLITNPSLATIMVDYVKQRILSAGAVQRLDRNDRPTTPEIKNETRQFRSSLRDASYQFSAQAHNDELA
VTPLVGLGKKSLLNKTIHHLMASADERLTICTPYFNLPALLVRNIIYLLREGKQVEIIVGDKTANDFYIPEDQPFKIIGA
LPYLYEINLRRFLSRLQPYVDNGQLIARLWKDGDNTYHLKGMWVDNNWQLITGNNLNPRAWRLDLENAILIHDPKHEMHE
QRAKELECIRTHTKVVSHYLELENIQQYPVKVRKLIRRLRRIRIDRLISRIL

Sequences:

>Translated_452_residues
MMLSKFKRSKHQQHLAQLPKLPQSVDDVQTLYCPKVFRSTLLELIAQATKRIFLVALYLEQDDAGRDVMNALYQAKQSHP
ELEIYVLVDWHRAQRGRIGAAAVNTNADWYCDMAAKHPNISVPVYGVPVNTREALGVLHLKGFIIDDTVIYSGASINDVY
LYQNDKYRYDRYQLITNPSLATIMVDYVKQRILSAGAVQRLDRNDRPTTPEIKNETRQFRSSLRDASYQFSAQAHNDELA
VTPLVGLGKKSLLNKTIHHLMASADERLTICTPYFNLPALLVRNIIYLLREGKQVEIIVGDKTANDFYIPEDQPFKIIGA
LPYLYEINLRRFLSRLQPYVDNGQLIARLWKDGDNTYHLKGMWVDNNWQLITGNNLNPRAWRLDLENAILIHDPKHEMHE
QRAKELECIRTHTKVVSHYLELENIQQYPVKVRKLIRRLRRIRIDRLISRIL
>Mature_452_residues
MMLSKFKRSKHQQHLAQLPKLPQSVDDVQTLYCPKVFRSTLLELIAQATKRIFLVALYLEQDDAGRDVMNALYQAKQSHP
ELEIYVLVDWHRAQRGRIGAAAVNTNADWYCDMAAKHPNISVPVYGVPVNTREALGVLHLKGFIIDDTVIYSGASINDVY
LYQNDKYRYDRYQLITNPSLATIMVDYVKQRILSAGAVQRLDRNDRPTTPEIKNETRQFRSSLRDASYQFSAQAHNDELA
VTPLVGLGKKSLLNKTIHHLMASADERLTICTPYFNLPALLVRNIIYLLREGKQVEIIVGDKTANDFYIPEDQPFKIIGA
LPYLYEINLRRFLSRLQPYVDNGQLIARLWKDGDNTYHLKGMWVDNNWQLITGNNLNPRAWRLDLENAILIHDPKHEMHE
QRAKELECIRTHTKVVSHYLELENIQQYPVKVRKLIRRLRRIRIDRLISRIL

Specific function: Unknown

COG id: COG1502

COG function: function code I; Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PLD phosphodiesterase domains [H]

Homologues:

Organism=Escherichia coli, GI87082134, Length=431, Percent_Identity=72.8538283062645, Blast_Score=663, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25143331, Length=409, Percent_Identity=23.960880195599, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI28572961, Length=409, Percent_Identity=24.4498777506112, Blast_Score=93, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016270
- InterPro:   IPR001736 [H]

Pfam domain/function: PF00614 PLDc [H]

EC number: =2.7.8.8 [H]

Molecular weight: Translated: 52492; Mature: 52492

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: PS50035 PLD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMLSKFKRSKHQQHLAQLPKLPQSVDDVQTLYCPKVFRSTLLELIAQATKRIFLVALYLE
CCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEE
QDDAGRDVMNALYQAKQSHPELEIYVLVDWHRAQRGRIGAAAVNTNADWYCDMAAKHPNI
CCCCCHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCEEEEECCCCCEEEEECCCCCCC
SVPVYGVPVNTREALGVLHLKGFIIDDTVIYSGASINDVYLYQNDKYRYDRYQLITNPSL
CEEEEECCCCCHHHHHHHEEECEEEECEEEECCCCCCEEEEEECCCEEECEEEEEECCCH
ATIMVDYVKQRILSAGAVQRLDRNDRPTTPEIKNETRQFRSSLRDASYQFSAQAHNDELA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCEE
VTPLVGLGKKSLLNKTIHHLMASADERLTICTPYFNLPALLVRNIIYLLREGKQVEIIVG
EECCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEEC
DKTANDFYIPEDQPFKIIGALPYLYEINLRRFLSRLQPYVDNGQLIARLWKDGDNTYHLK
CCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCEEEEE
GMWVDNNWQLITGNNLNPRAWRLDLENAILIHDPKHEMHEQRAKELECIRTHTKVVSHYL
EEEECCCEEEEECCCCCCCEEEEECCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
ELENIQQYPVKVRKLIRRLRRIRIDRLISRIL
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MMLSKFKRSKHQQHLAQLPKLPQSVDDVQTLYCPKVFRSTLLELIAQATKRIFLVALYLE
CCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEE
QDDAGRDVMNALYQAKQSHPELEIYVLVDWHRAQRGRIGAAAVNTNADWYCDMAAKHPNI
CCCCCHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCEEEEECCCCCEEEEECCCCCCC
SVPVYGVPVNTREALGVLHLKGFIIDDTVIYSGASINDVYLYQNDKYRYDRYQLITNPSL
CEEEEECCCCCHHHHHHHEEECEEEECEEEECCCCCCEEEEEECCCEEECEEEEEECCCH
ATIMVDYVKQRILSAGAVQRLDRNDRPTTPEIKNETRQFRSSLRDASYQFSAQAHNDELA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCEE
VTPLVGLGKKSLLNKTIHHLMASADERLTICTPYFNLPALLVRNIIYLLREGKQVEIIVG
EECCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCEEEEEEC
DKTANDFYIPEDQPFKIIGALPYLYEINLRRFLSRLQPYVDNGQLIARLWKDGDNTYHLK
CCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCEEEEE
GMWVDNNWQLITGNNLNPRAWRLDLENAILIHDPKHEMHEQRAKELECIRTHTKVVSHYL
EEEECCCEEEEECCCCCCCEEEEECCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHH
ELENIQQYPVKVRKLIRRLRRIRIDRLISRIL
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2002065; 9205837; 9278503; 1323044 [H]