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The map label for this gene is copA

Identifier: 218930131

GI number: 218930131

Start: 3441490

End: 3444375

Strand: Direct

Name: copA

Synonym: YPO3086

Alternate gene names: 218930131

Gene position: 3441490-3444375 (Clockwise)

Preceding gene: 218930129

Following gene: 218930132

Centisome position: 73.95

GC content: 53.01

Gene sequence:

>2886_bases
ATGTTGCAAACCACACTGCTCGCCTTACAAGGACTTTCTTGTATGAATTGTGCTCAACGCGTTAAAGCCGCGTTGGAAAG
CCGTGAGGATGTTCACCATGCTGAAGTGAATGTTCACTACGCTAAAGTGACTGGTGAAGCCGACACTCATGCACTCATTG
AAACGATCAAACAGACCGGTTATCAGGCTACAGAAGCCCAAACGCCGGACGTTGAATTACACCTATCAGGATTGAGCTGC
GGGCATTGCACTGAGACCGTCCGTAAAGCGCTGGAAGCGGTTTCGGGGGTTATTTCTGCCGATGTAACCCTCGAGAGTGC
CAACGTGTACGGCAAGGCCGATATACAGACATTGATTGCCGCAGTGGAACAGGCTGGCTATCACGCCACACAGCAAGGTA
TCGACTCCCCAAAAACTGAGCCGCTGACACACTCAGCCCAATCTCAGCCGGAATCTCTGGCAGCGGCCCCGAATACAGTT
CCGGCAACAAACGTGGCTTTAGCCACAAGTACGGTTTCTGATACAAATACCGTTTTACCTACAAATACCGCTTTACCTAC
AAATACAACGTCGACAACTTCAACAGCCGATACGGCGTCAGCCACCAGCACGGCACCGGTGATCAATCCGCTGCCAGTGA
CCGAATCAGTGGCCCAGCCGGCAGCCTCAGAAGGGGAGAGTGTTCAGCTATTACTGACGGGGATGAGCTGTGCCAGTTGT
GTCTCTAAAGTACAAAATGCATTGCAACGTGTTGATGGGGTTCAGGTGGCCCGCGTTAATCTGGCTGAGCGCAGTGCATT
GGTCACAGGGACCCAAAATAACGAAGCCTTAATCGCTGCGGTTAAAAATGCCGGTTACGGCGCGGAAATTATTGAAGACG
AAGGGGAGCGACGCGAGCGGCAACAGCAAATGTCGCAAGCCAGTATGAAGCGCTTCCAATGGCAAGCGGCATTAGGTCTG
TTGTTAGGTATCCCATTGATGGCCTGGGGGCTGTTTGGCGGTAGCATGACGCTGACGCCAGAAACCCAAACGCCCTGGCT
TATCATCGGGATTATCACGTTGCTGGTAATGATATTTGCGGGTGGTCACTTCTACCGTAATGCGTGGGTCAGCCTGAAAA
ATGGCAGAGCGACCATGGATACCTTGGTCGCTCTGGGGACAGGTGCGGCCTGGATCTATTCCATCACCGTCAATATCTGG
CCAGATGTTTTCCCTATGGAGGCTCGTCACCTTTATTACGAAGCCAGTGCCATGATCATTGGTTTGATTAACCTTGGTCA
TGCGATGGAACAACGTGCCAGACAGCGCTCATCTAATGCGCTCGAACGCCTGTTAGATTTGGCCCCACCAACGGCAAAGT
TAGTGACCGATGACGGCGAGAAGGTGATCCCGCTGGCTGATGTCCAACTGGGGATGATCCTACGCCTGACTACTGGCGAT
CGCGTACCGGTTGACGGCGAGATTGTGCAGGGCGAAGTGTGGATGGATGAAGCGATGCTGACTGGTGAGCCGATCCCACA
ACAGAAATCAGTCGGTGATATTGTCCACGCGGGGACACAAGTACAAGATGGAACCGTACAATTTCGGGCTAGCGCTATCG
GTAGCCAAACGACCTTGGCGCGGATTATCAAACTAGTCCGTCAGGCACAAAGCAGTAAACCGGAAATCGGCAAATTGGCA
GACCGTATCTCTGCGGTATTCGTCCCAACGGTGGTGGTCATTGCCATTGTCGCTGGCCTGATTTGGTATTTCTTCGGCCC
ACAACCCCAGTTGGTCTATACCCTGGTGGTGGCCACCACGGTGTTAATTATCGCCTGCCCTTGTGCTTTGGGCTTAGCGA
CACCGATGTCGATTATCTCTGGCGTCGGCCGGGCCGCTGAATTTGGTGTATTGGTTCGAGATGCAGATGCATTGCAGCAA
GCCAGTAACCTCGATACGTTAGTGTTCGATAAAACCGGCACACTGACTGAGGGGCACCCGCAGGTAGTGGCAATCCATAC
CTTTAATGGTGTCAGTGAGCAACAGGCTTTGGGCTGGGCGGCAGCATTGGAAACGGGATCAAATCACCCGCTGGCGCGCG
CTATCTTACAACGTGCTGAAGGGCTGACATTGGCCACCGCCAGCCAATTTCGTACATTGCGCGGTTTGGGGGTCAGTGGT
GAAGTTGACGGCATTCCACTGCTCCTTGGCAATAATCGGCTACTGGAAGAGCAACAGATTGATACCCGCGAGCTGCAATC
ATTGATACAGCAACAAGCGGAAAGTGGCGCAACACCGGTTATTCTGACCGCCAATGGTAAGCCCGCCGCACTGTTATCGA
TCCGTGATCCATTGCGCGAAGACAGTATCGGCGCATTACAGCGGCTGCATCAATTGGGCTATAGTCTGGTGATGTTGACC
GGTGACAACCCTATTACCGCCAATGCCATTGCGAAAGAAGCCGGTATTGATCGTGTGATCGCGGGCGTTCTGCCAGATGG
CAAAGCCGATGCTATCAAGCAACTGCAAGCGGCCGGGCATAAAGTGGCGATGATTGGTGATGGCATTAACGATGCTCCTG
CATTAGCACAAGCGGATGTCGGGATTGCCATGGGGGGCGGCAGTGATATCGCGATTGAAACCGCGGCGATTACCCTTATG
CGTCACAGTTTGTACGGTGTTGTCGATGCGGTAGAACTTTCCAAAGCAACATTACGTAACATGAAGCAAAACCTGTTGGG
CGCGTTCTTCTACAATGCGCTGGGCATTCCCATTGCCGCAGGGATTTTATATCCCTTCACCGGTACATTGCTCAGCCCGG
TCGTCGCCGGAGCGGCAATGGCGTTGTCGTCCATTACGGTCGTCAGTAACGCTAACCGTTTACTGCGCTTTAAGCCTAAA
CAGTAA

Upstream 100 bases:

>100_bases
AACAAAATATTACCGTCATTAATGTATGGGGCAGGTAATACCGACTAAGCTTATTCTGGTGAATTTATGAGTAAGTTTTT
ACTCAATAAGGAGTTAAATA

Downstream 100 bases:

>100_bases
ATGCTTTCAGTGACCTCAATGGCGCACAATATCGTTTTGTGCGCCATTGAGCGTTGATATCCAAAATGTAAGTGCCGCTA
ACAACGCTACAATTTCAAGT

Product: copper exporting ATPase

Products: ADP; Orthophosphate. [C]

Alternate protein names: NA

Number of amino acids: Translated: 961; Mature: 961

Protein sequence:

>961_residues
MLQTTLLALQGLSCMNCAQRVKAALESREDVHHAEVNVHYAKVTGEADTHALIETIKQTGYQATEAQTPDVELHLSGLSC
GHCTETVRKALEAVSGVISADVTLESANVYGKADIQTLIAAVEQAGYHATQQGIDSPKTEPLTHSAQSQPESLAAAPNTV
PATNVALATSTVSDTNTVLPTNTALPTNTTSTTSTADTASATSTAPVINPLPVTESVAQPAASEGESVQLLLTGMSCASC
VSKVQNALQRVDGVQVARVNLAERSALVTGTQNNEALIAAVKNAGYGAEIIEDEGERRERQQQMSQASMKRFQWQAALGL
LLGIPLMAWGLFGGSMTLTPETQTPWLIIGIITLLVMIFAGGHFYRNAWVSLKNGRATMDTLVALGTGAAWIYSITVNIW
PDVFPMEARHLYYEASAMIIGLINLGHAMEQRARQRSSNALERLLDLAPPTAKLVTDDGEKVIPLADVQLGMILRLTTGD
RVPVDGEIVQGEVWMDEAMLTGEPIPQQKSVGDIVHAGTQVQDGTVQFRASAIGSQTTLARIIKLVRQAQSSKPEIGKLA
DRISAVFVPTVVVIAIVAGLIWYFFGPQPQLVYTLVVATTVLIIACPCALGLATPMSIISGVGRAAEFGVLVRDADALQQ
ASNLDTLVFDKTGTLTEGHPQVVAIHTFNGVSEQQALGWAAALETGSNHPLARAILQRAEGLTLATASQFRTLRGLGVSG
EVDGIPLLLGNNRLLEEQQIDTRELQSLIQQQAESGATPVILTANGKPAALLSIRDPLREDSIGALQRLHQLGYSLVMLT
GDNPITANAIAKEAGIDRVIAGVLPDGKADAIKQLQAAGHKVAMIGDGINDAPALAQADVGIAMGGGSDIAIETAAITLM
RHSLYGVVDAVELSKATLRNMKQNLLGAFFYNALGIPIAAGILYPFTGTLLSPVVAGAAMALSSITVVSNANRLLRFKPK
Q

Sequences:

>Translated_961_residues
MLQTTLLALQGLSCMNCAQRVKAALESREDVHHAEVNVHYAKVTGEADTHALIETIKQTGYQATEAQTPDVELHLSGLSC
GHCTETVRKALEAVSGVISADVTLESANVYGKADIQTLIAAVEQAGYHATQQGIDSPKTEPLTHSAQSQPESLAAAPNTV
PATNVALATSTVSDTNTVLPTNTALPTNTTSTTSTADTASATSTAPVINPLPVTESVAQPAASEGESVQLLLTGMSCASC
VSKVQNALQRVDGVQVARVNLAERSALVTGTQNNEALIAAVKNAGYGAEIIEDEGERRERQQQMSQASMKRFQWQAALGL
LLGIPLMAWGLFGGSMTLTPETQTPWLIIGIITLLVMIFAGGHFYRNAWVSLKNGRATMDTLVALGTGAAWIYSITVNIW
PDVFPMEARHLYYEASAMIIGLINLGHAMEQRARQRSSNALERLLDLAPPTAKLVTDDGEKVIPLADVQLGMILRLTTGD
RVPVDGEIVQGEVWMDEAMLTGEPIPQQKSVGDIVHAGTQVQDGTVQFRASAIGSQTTLARIIKLVRQAQSSKPEIGKLA
DRISAVFVPTVVVIAIVAGLIWYFFGPQPQLVYTLVVATTVLIIACPCALGLATPMSIISGVGRAAEFGVLVRDADALQQ
ASNLDTLVFDKTGTLTEGHPQVVAIHTFNGVSEQQALGWAAALETGSNHPLARAILQRAEGLTLATASQFRTLRGLGVSG
EVDGIPLLLGNNRLLEEQQIDTRELQSLIQQQAESGATPVILTANGKPAALLSIRDPLREDSIGALQRLHQLGYSLVMLT
GDNPITANAIAKEAGIDRVIAGVLPDGKADAIKQLQAAGHKVAMIGDGINDAPALAQADVGIAMGGGSDIAIETAAITLM
RHSLYGVVDAVELSKATLRNMKQNLLGAFFYNALGIPIAAGILYPFTGTLLSPVVAGAAMALSSITVVSNANRLLRFKPK
Q
>Mature_961_residues
MLQTTLLALQGLSCMNCAQRVKAALESREDVHHAEVNVHYAKVTGEADTHALIETIKQTGYQATEAQTPDVELHLSGLSC
GHCTETVRKALEAVSGVISADVTLESANVYGKADIQTLIAAVEQAGYHATQQGIDSPKTEPLTHSAQSQPESLAAAPNTV
PATNVALATSTVSDTNTVLPTNTALPTNTTSTTSTADTASATSTAPVINPLPVTESVAQPAASEGESVQLLLTGMSCASC
VSKVQNALQRVDGVQVARVNLAERSALVTGTQNNEALIAAVKNAGYGAEIIEDEGERRERQQQMSQASMKRFQWQAALGL
LLGIPLMAWGLFGGSMTLTPETQTPWLIIGIITLLVMIFAGGHFYRNAWVSLKNGRATMDTLVALGTGAAWIYSITVNIW
PDVFPMEARHLYYEASAMIIGLINLGHAMEQRARQRSSNALERLLDLAPPTAKLVTDDGEKVIPLADVQLGMILRLTTGD
RVPVDGEIVQGEVWMDEAMLTGEPIPQQKSVGDIVHAGTQVQDGTVQFRASAIGSQTTLARIIKLVRQAQSSKPEIGKLA
DRISAVFVPTVVVIAIVAGLIWYFFGPQPQLVYTLVVATTVLIIACPCALGLATPMSIISGVGRAAEFGVLVRDADALQQ
ASNLDTLVFDKTGTLTEGHPQVVAIHTFNGVSEQQALGWAAALETGSNHPLARAILQRAEGLTLATASQFRTLRGLGVSG
EVDGIPLLLGNNRLLEEQQIDTRELQSLIQQQAESGATPVILTANGKPAALLSIRDPLREDSIGALQRLHQLGYSLVMLT
GDNPITANAIAKEAGIDRVIAGVLPDGKADAIKQLQAAGHKVAMIGDGINDAPALAQADVGIAMGGGSDIAIETAAITLM
RHSLYGVVDAVELSKATLRNMKQNLLGAFFYNALGIPIAAGILYPFTGTLLSPVVAGAAMALSSITVVSNANRLLRFKPK
Q

Specific function: Involved in copper export

COG id: COG2217

COG function: function code P; Cation transport ATPase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 HMA domains

Homologues:

Organism=Homo sapiens, GI55743071, Length=996, Percent_Identity=30.7228915662651, Blast_Score=418, Evalue=1e-116,
Organism=Homo sapiens, GI115529486, Length=1022, Percent_Identity=28.9628180039139, Blast_Score=395, Evalue=1e-109,
Organism=Homo sapiens, GI55743073, Length=547, Percent_Identity=34.0036563071298, Blast_Score=295, Evalue=1e-79,
Organism=Homo sapiens, GI28373109, Length=159, Percent_Identity=34.5911949685535, Blast_Score=88, Evalue=3e-17,
Organism=Homo sapiens, GI28373107, Length=159, Percent_Identity=34.5911949685535, Blast_Score=88, Evalue=3e-17,
Organism=Homo sapiens, GI28373105, Length=159, Percent_Identity=34.5911949685535, Blast_Score=88, Evalue=4e-17,
Organism=Homo sapiens, GI28373115, Length=159, Percent_Identity=34.5911949685535, Blast_Score=88, Evalue=4e-17,
Organism=Homo sapiens, GI28373111, Length=159, Percent_Identity=34.5911949685535, Blast_Score=88, Evalue=4e-17,
Organism=Homo sapiens, GI28373103, Length=159, Percent_Identity=34.5911949685535, Blast_Score=88, Evalue=4e-17,
Organism=Homo sapiens, GI28373113, Length=159, Percent_Identity=34.5911949685535, Blast_Score=88, Evalue=4e-17,
Organism=Homo sapiens, GI10835220, Length=186, Percent_Identity=32.258064516129, Blast_Score=87, Evalue=9e-17,
Organism=Homo sapiens, GI27886529, Length=186, Percent_Identity=32.258064516129, Blast_Score=87, Evalue=1e-16,
Organism=Homo sapiens, GI310128958, Length=186, Percent_Identity=32.258064516129, Blast_Score=85, Evalue=3e-16,
Organism=Homo sapiens, GI209413709, Length=212, Percent_Identity=28.7735849056604, Blast_Score=83, Evalue=2e-15,
Organism=Homo sapiens, GI24638454, Length=212, Percent_Identity=28.7735849056604, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI4502285, Length=212, Percent_Identity=28.7735849056604, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI118498343, Length=160, Percent_Identity=36.875, Blast_Score=78, Evalue=5e-14,
Organism=Escherichia coli, GI1786691, Length=891, Percent_Identity=66.5544332210999, Blast_Score=1147, Evalue=0.0,
Organism=Escherichia coli, GI1789879, Length=734, Percent_Identity=31.7438692098093, Blast_Score=292, Evalue=8e-80,
Organism=Escherichia coli, GI1786914, Length=460, Percent_Identity=28.695652173913, Blast_Score=150, Evalue=4e-37,
Organism=Escherichia coli, GI2367363, Length=613, Percent_Identity=23.3278955954323, Blast_Score=120, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI17556548, Length=815, Percent_Identity=32.3926380368098, Blast_Score=372, Evalue=1e-103,
Organism=Caenorhabditis elegans, GI71997269, Length=583, Percent_Identity=24.8713550600343, Blast_Score=109, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI71997262, Length=583, Percent_Identity=24.8713550600343, Blast_Score=109, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI71997275, Length=583, Percent_Identity=24.8713550600343, Blast_Score=109, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI17554158, Length=186, Percent_Identity=30.1075268817204, Blast_Score=84, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI71988506, Length=186, Percent_Identity=30.1075268817204, Blast_Score=84, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI193210130, Length=186, Percent_Identity=30.1075268817204, Blast_Score=84, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6320475, Length=639, Percent_Identity=35.8372456964006, Blast_Score=369, Evalue=1e-102,
Organism=Saccharomyces cerevisiae, GI6319772, Length=684, Percent_Identity=29.2397660818713, Blast_Score=268, Evalue=2e-72,
Organism=Saccharomyces cerevisiae, GI6325221, Length=515, Percent_Identity=26.0194174757282, Blast_Score=113, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6321430, Length=512, Percent_Identity=25.78125, Blast_Score=109, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6321271, Length=166, Percent_Identity=32.5301204819277, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI221329854, Length=579, Percent_Identity=31.9516407599309, Blast_Score=251, Evalue=1e-66,
Organism=Drosophila melanogaster, GI17136664, Length=186, Percent_Identity=30.1075268817204, Blast_Score=86, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24762455, Length=186, Percent_Identity=30.1075268817204, Blast_Score=86, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24762453, Length=186, Percent_Identity=30.1075268817204, Blast_Score=86, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24762447, Length=186, Percent_Identity=30.1075268817204, Blast_Score=86, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24762457, Length=186, Percent_Identity=30.1075268817204, Blast_Score=86, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24762449, Length=186, Percent_Identity=30.1075268817204, Blast_Score=86, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24762445, Length=186, Percent_Identity=30.1075268817204, Blast_Score=86, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24762451, Length=186, Percent_Identity=30.1075268817204, Blast_Score=86, Evalue=1e-16,
Organism=Drosophila melanogaster, GI161085803, Length=163, Percent_Identity=32.5153374233129, Blast_Score=77, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24668708, Length=163, Percent_Identity=32.5153374233129, Blast_Score=77, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24668704, Length=163, Percent_Identity=32.5153374233129, Blast_Score=77, Evalue=6e-14,
Organism=Drosophila melanogaster, GI281366617, Length=163, Percent_Identity=32.5153374233129, Blast_Score=77, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24668696, Length=163, Percent_Identity=32.5153374233129, Blast_Score=77, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COPA_YERPE (Q8ZCA7)

Other databases:

- EMBL:   AL590842
- EMBL:   AE009952
- EMBL:   AE017042
- PIR:   AE0375
- RefSeq:   NP_668419.1
- RefSeq:   NP_992220.1
- RefSeq:   YP_002348006.1
- ProteinModelPortal:   Q8ZCA7
- GeneID:   1146039
- GeneID:   1175907
- GeneID:   2764600
- GenomeReviews:   AE009952_GR
- GenomeReviews:   AE017042_GR
- GenomeReviews:   AL590842_GR
- KEGG:   ype:YPO3086
- KEGG:   ypk:y1093
- KEGG:   ypm:YP_0838
- HOGENOM:   HBG507745
- OMA:   INGMSCA
- ProtClustDB:   PRK10671
- BioCyc:   YPES187410:Y1093-MONOMER
- BioCyc:   YPES214092:YPO3086-MONOMER
- BRENDA:   3.6.3.4
- InterPro:   IPR008250
- InterPro:   IPR006403
- InterPro:   IPR006416
- InterPro:   IPR001757
- InterPro:   IPR018303
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR017969
- InterPro:   IPR006121
- InterPro:   IPR000150
- Gene3D:   G3DSA:3.40.50.1000
- PANTHER:   PTHR11939
- PRINTS:   PR00119
- PRINTS:   PR00943
- TIGRFAMs:   TIGR01511
- TIGRFAMs:   TIGR01525
- TIGRFAMs:   TIGR01494

Pfam domain/function: PF00122 E1-E2_ATPase; PF00403 HMA; PF00702 Hydrolase; SSF55008 HeavyMe_transpt; SSF56784 SSF56784

EC number: 3.6.3.4 [C]

Molecular weight: Translated: 101410; Mature: 101410

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS00154 ATPASE_E1_E2; PS01047 HMA_1; PS50846 HMA_2; PS01229 COF_2

Important sites: ACT_SITE 650-650

Signals:

None

Transmembrane regions:

HASH(0xf39fa9c)-; HASH(0xf7f2ed4)-; HASH(0xf84c8c8)-; HASH(0xf55f6a8)-; HASH(0xed200f8)-; HASH(0xf222de4)-; HASH(0xf7ebbf0)-; HASH(0xf3d5d48)-;

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQTTLLALQGLSCMNCAQRVKAALESREDVHHAEVNVHYAKVTGEADTHALIETIKQTG
CCCHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCHHHHHHHHHHHCC
YQATEAQTPDVELHLSGLSCGHCTETVRKALEAVSGVISADVTLESANVYGKADIQTLIA
CCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHH
AVEQAGYHATQQGIDSPKTEPLTHSAQSQPESLAAAPNTVPATNVALATSTVSDTNTVLP
HHHHHCCHHHHHCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCEEEEEEECCCCCCCCC
TNTALPTNTTSTTSTADTASATSTAPVINPLPVTESVAQPAASEGESVQLLLTGMSCASC
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCEEEEEEECCHHHHH
VSKVQNALQRVDGVQVARVNLAERSALVTGTQNNEALIAAVKNAGYGAEIIEDEGERRER
HHHHHHHHHHHCCCEEEEEEHHHCCEEEECCCCCCEEEEEEECCCCCCHHHCCCHHHHHH
QQQMSQASMKRFQWQAALGLLLGIPLMAWGLFGGSMTLTPETQTPWLIIGIITLLVMIFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHHH
GGHFYRNAWVSLKNGRATMDTLVALGTGAAWIYSITVNIWPDVFPMEARHLYYEASAMII
CCCEEEEEEEEECCCCHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCHHHHHEEHHHHHH
GLINLGHAMEQRARQRSSNALERLLDLAPPTAKLVTDDGEKVIPLADVQLGMILRLTTGD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCEEEEEECCCCCEEEEEECCC
RVPVDGEIVQGEVWMDEAMLTGEPIPQQKSVGDIVHAGTQVQDGTVQFRASAIGSQTTLA
CCCCCCEEEECEEECCCHHHCCCCCCCCCCHHHHHHCCCCCCCCCEEEEHHHCCCHHHHH
RIIKLVRQAQSSKPEIGKLADRISAVFVPTVVVIAIVAGLIWYFFGPQPQLVYTLVVATT
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
VLIIACPCALGLATPMSIISGVGRAAEFGVLVRDADALQQASNLDTLVFDKTGTLTEGHP
HHHHHHHHHHHHHHHHHHHHHCCCHHHCCEEEECHHHHHHHCCCCEEEEECCCCCCCCCC
QVVAIHTFNGVSEQQALGWAAALETGSNHPLARAILQRAEGLTLATASQFRTLRGLGVSG
CEEEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEEHHHHHHHHCCCCCC
EVDGIPLLLGNNRLLEEQQIDTRELQSLIQQQAESGATPVILTANGKPAALLSIRDPLRE
CCCCEEEEECCCCCCCHHCCCHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEECCCCCC
DSIGALQRLHQLGYSLVMLTGDNPITANAIAKEAGIDRVIAGVLPDGKADAIKQLQAAGH
CHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHCHHHHHHHCCCCCHHHHHHHHHHCCC
KVAMIGDGINDAPALAQADVGIAMGGGSDIAIETAAITLMRHSLYGVVDAVELSKATLRN
EEEEEECCCCCCCCHHHCCCCEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MKQNLLGAFFYNALGIPIAAGILYPFTGTLLSPVVAGAAMALSSITVVSNANRLLRFKPK
HHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEEECCC
Q
H
>Mature Secondary Structure
MLQTTLLALQGLSCMNCAQRVKAALESREDVHHAEVNVHYAKVTGEADTHALIETIKQTG
CCCHHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCHHHHHHHHHHHCC
YQATEAQTPDVELHLSGLSCGHCTETVRKALEAVSGVISADVTLESANVYGKADIQTLIA
CCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHHHHHHHH
AVEQAGYHATQQGIDSPKTEPLTHSAQSQPESLAAAPNTVPATNVALATSTVSDTNTVLP
HHHHHCCHHHHHCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCEEEEEEECCCCCCCCC
TNTALPTNTTSTTSTADTASATSTAPVINPLPVTESVAQPAASEGESVQLLLTGMSCASC
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCEEEEEEECCHHHHH
VSKVQNALQRVDGVQVARVNLAERSALVTGTQNNEALIAAVKNAGYGAEIIEDEGERRER
HHHHHHHHHHHCCCEEEEEEHHHCCEEEECCCCCCEEEEEEECCCCCCHHHCCCHHHHHH
QQQMSQASMKRFQWQAALGLLLGIPLMAWGLFGGSMTLTPETQTPWLIIGIITLLVMIFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHHH
GGHFYRNAWVSLKNGRATMDTLVALGTGAAWIYSITVNIWPDVFPMEARHLYYEASAMII
CCCEEEEEEEEECCCCHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCHHHHHEEHHHHHH
GLINLGHAMEQRARQRSSNALERLLDLAPPTAKLVTDDGEKVIPLADVQLGMILRLTTGD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCEEEEEECCCCCEEEEEECCC
RVPVDGEIVQGEVWMDEAMLTGEPIPQQKSVGDIVHAGTQVQDGTVQFRASAIGSQTTLA
CCCCCCEEEECEEECCCHHHCCCCCCCCCCHHHHHHCCCCCCCCCEEEEHHHCCCHHHHH
RIIKLVRQAQSSKPEIGKLADRISAVFVPTVVVIAIVAGLIWYFFGPQPQLVYTLVVATT
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
VLIIACPCALGLATPMSIISGVGRAAEFGVLVRDADALQQASNLDTLVFDKTGTLTEGHP
HHHHHHHHHHHHHHHHHHHHHCCCHHHCCEEEECHHHHHHHCCCCEEEEECCCCCCCCCC
QVVAIHTFNGVSEQQALGWAAALETGSNHPLARAILQRAEGLTLATASQFRTLRGLGVSG
CEEEEEECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEEHHHHHHHHCCCCCC
EVDGIPLLLGNNRLLEEQQIDTRELQSLIQQQAESGATPVILTANGKPAALLSIRDPLRE
CCCCEEEEECCCCCCCHHCCCHHHHHHHHHHHHHCCCCCEEEECCCCCEEEEEECCCCCC
DSIGALQRLHQLGYSLVMLTGDNPITANAIAKEAGIDRVIAGVLPDGKADAIKQLQAAGH
CHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHCHHHHHHHCCCCCHHHHHHHHHHCCC
KVAMIGDGINDAPALAQADVGIAMGGGSDIAIETAAITLMRHSLYGVVDAVELSKATLRN
EEEEEECCCCCCCCHHHCCCCEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MKQNLLGAFFYNALGIPIAAGILYPFTGTLLSPVVAGAAMALSSITVVSNANRLLRFKPK
HHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEEECCC
Q
H

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Cu [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O [C]

Specific reaction: ATP + H2O = ADP + Orthophosphate. [C]

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430