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The map label for this gene is nanE [H]

Identifier: 218930068

GI number: 218930068

Start: 3376403

End: 3377104

Strand: Direct

Name: nanE [H]

Synonym: YPO3023

Alternate gene names: 218930068

Gene position: 3376403-3377104 (Clockwise)

Preceding gene: 218930056

Following gene: 218930069

Centisome position: 72.55

GC content: 55.27

Gene sequence:

>702_bases
GTGAGCAATCTAAGCAATCTCCGCCACAAGCTCCAAAATGGCCTTATCGCCTCATGTCAACCGGTTCCCGGCAGTGCCAT
GGATACGCCTGAGATCGTCGCGGCAATGGCCTGTGCCGCACTGGCGGGTGGTGCTGTCGGTCTACGAATTGAAGGCATCA
GCAACATCCAGGCAGTACGTCGGGCTACAGATGCCCCCATTATTGGCATTATTAAACGCGACTTGCCTGACTCCGAGGTC
AGAATTACCCCTTGGCTGGAAGATATCGATGCACTCAGTGCCGCCGGAGCAGATATTATTGCTTTTGATGTTACCTGCCG
TGAGCGCCCAGTCTCCGTGGCCGATTTATATCAGCGAGCGCGGGCAACCGGCTGCCTGACCATGGCCGATGCCTCCAATA
TTGACGACGGCCTGTTGGCTCATCATCTGGGGATTGATTTTATCGGCACCACCCTTTCCGGCTACACTCAAGCCACCGTG
CCAACCGAGCCCGATCTGGCCTTAGTGACACAGTTAGCGCAAGCCGGGTGCAGGGTCATTGCCGAAGGCCGTTACCATTC
ACCGGCCCTGGCGGCAGCAGCAATATCAGCGGGGGCATATGCCGTTACGGTCGGTTCCGCCATTACCCGTATAGAACATA
TTTGCGGTTGGTTTTGCGATGCAATTAAGCAGTGTGAAACAGAAAAACTGACCGAATACTGA

Upstream 100 bases:

>100_bases
TCGTCATACATCGCCCTTCTTATCGTTGCACCTGACGGATAAACGATCTAACATAATGGAGTTAAACTTCATTTATAATT
TCACATCGGAGTTAAAGACC

Downstream 100 bases:

>100_bases
TTATCGTCATTATTGATTATGGCCCACAGGGCCCTCCACTCTCCCAGTTTATAAGGATGCGTATGAAAAAGTTAACCGGC
CTGATCGCAGCTCCGCACAC

Product: N-acetylmannosamine-6-phosphate 2-epimerase

Products: NA

Alternate protein names: ManNAc-6-P epimerase [H]

Number of amino acids: Translated: 233; Mature: 232

Protein sequence:

>233_residues
MSNLSNLRHKLQNGLIASCQPVPGSAMDTPEIVAAMACAALAGGAVGLRIEGISNIQAVRRATDAPIIGIIKRDLPDSEV
RITPWLEDIDALSAAGADIIAFDVTCRERPVSVADLYQRARATGCLTMADASNIDDGLLAHHLGIDFIGTTLSGYTQATV
PTEPDLALVTQLAQAGCRVIAEGRYHSPALAAAAISAGAYAVTVGSAITRIEHICGWFCDAIKQCETEKLTEY

Sequences:

>Translated_233_residues
MSNLSNLRHKLQNGLIASCQPVPGSAMDTPEIVAAMACAALAGGAVGLRIEGISNIQAVRRATDAPIIGIIKRDLPDSEV
RITPWLEDIDALSAAGADIIAFDVTCRERPVSVADLYQRARATGCLTMADASNIDDGLLAHHLGIDFIGTTLSGYTQATV
PTEPDLALVTQLAQAGCRVIAEGRYHSPALAAAAISAGAYAVTVGSAITRIEHICGWFCDAIKQCETEKLTEY
>Mature_232_residues
SNLSNLRHKLQNGLIASCQPVPGSAMDTPEIVAAMACAALAGGAVGLRIEGISNIQAVRRATDAPIIGIIKRDLPDSEVR
ITPWLEDIDALSAAGADIIAFDVTCRERPVSVADLYQRARATGCLTMADASNIDDGLLAHHLGIDFIGTTLSGYTQATVP
TEPDLALVTQLAQAGCRVIAEGRYHSPALAAAAISAGAYAVTVGSAITRIEHICGWFCDAIKQCETEKLTEY

Specific function: Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (Potential) [H]

COG id: COG3010

COG function: function code G; Putative N-acetylmannosamine-6-phosphate epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nanE family [H]

Homologues:

Organism=Escherichia coli, GI1789617, Length=226, Percent_Identity=60.1769911504425, Blast_Score=247, Evalue=5e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR007260
- InterPro:   IPR011060 [H]

Pfam domain/function: PF04131 NanE [H]

EC number: =5.1.3.9 [H]

Molecular weight: Translated: 24459; Mature: 24328

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNLSNLRHKLQNGLIASCQPVPGSAMDTPEIVAAMACAALAGGAVGLRIEGISNIQAVR
CCCHHHHHHHHHCCCEEECCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHH
RATDAPIIGIIKRDLPDSEVRITPWLEDIDALSAAGADIIAFDVTCRERPVSVADLYQRA
HHCCCCEEEEEECCCCCCCEEEECCHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHH
RATGCLTMADASNIDDGLLAHHLGIDFIGTTLSGYTQATVPTEPDLALVTQLAQAGCRVI
HHCCEEEECCCCCCCHHHHHHHHCHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHCCEEE
AEGRYHSPALAAAAISAGAYAVTVGSAITRIEHICGWFCDAIKQCETEKLTEY
ECCCCCCHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCC
>Mature Secondary Structure 
SNLSNLRHKLQNGLIASCQPVPGSAMDTPEIVAAMACAALAGGAVGLRIEGISNIQAVR
CCHHHHHHHHHCCCEEECCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHH
RATDAPIIGIIKRDLPDSEVRITPWLEDIDALSAAGADIIAFDVTCRERPVSVADLYQRA
HHCCCCEEEEEECCCCCCCEEEECCHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHH
RATGCLTMADASNIDDGLLAHHLGIDFIGTTLSGYTQATVPTEPDLALVTQLAQAGCRVI
HHCCEEEECCCCCCCHHHHHHHHCHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHCCEEE
AEGRYHSPALAAAAISAGAYAVTVGSAITRIEHICGWFCDAIKQCETEKLTEY
ECCCCCCHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA