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The map label for this gene is engA

Identifier: 218929935

GI number: 218929935

Start: 3209939

End: 3211426

Strand: Reverse

Name: engA

Synonym: YPO2875

Alternate gene names: 218929935

Gene position: 3211426-3209939 (Counterclockwise)

Preceding gene: 218929936

Following gene: 218929934

Centisome position: 69.01

GC content: 47.92

Gene sequence:

>1488_bases
ATGATACCTGTCATCGCGCTGGTCGGGCGCCCGAATGTGGGTAAATCCACTTTATTTAACCGCTTAACGCATACCCGTGA
TGCATTAGTTGCGGATTTTCCCGGGCTAACGCGTGATCGTAAATATGGTCGTGCCGAGGTCGAAGGGCATGAGTTTATTG
TTGTCGATACCGGAGGTATTGATGGCACAGAAGATGGTGTAGAAACCAAGATGGCAGGTCAATCGTTATTGGCGATTGAA
GAGGCGGATATTGTCCTGTTTATGGTCGATGCACGCGCTGGCTTGATGCCAGCAGATCAGGGGATTGCTCAACATCTGCG
CAGCCGTGAAAAAGCCACTTTCCTGGTCGCTAACAAAACCGATGGTATTGATCCTGATACTGCTACAGCAGATTTCTACT
CTTTAGGTTTAGGCGAAGTTCACGCTATTGCTGCCTCCCATGGGCGTGGCGTTACTCAACTGATTGAAGATGTCATGGCA
CCTTATATGGATGCCGAGGAACCTGAAGTTGAGTTGACCGAAGAAGAGGAAAATGCGGCCTATTGGGCTGAGCAGGAAGC
TCAAGGTGAAGATGTTCCGCCTGAAGATCCGGAAGATGATTTTGATCCACGGACTTTGCCAATTAAATTGGCGATCGTGG
GGCGTCCTAACGTAGGCAAGTCCACACTAACTAACCGTATTCTCGGTGAAGATCGTGTGGTGGTTTACGACATGCCGGGT
ACGACGCGCGATAGCATTTATATCCCGATGACGCGTGATGACCGTGAATATATTCTGATTGATACGGCGGGTGTACGTAA
GCGCGGTAAAATCACTGAAACGGTTGAAAAATTCTCCGTCATTAAGACGTTACAGGCAATTGAAGACTCTAACGTTGTCC
TGTTGGTTATTGATGCCCGTGATGGAATTTCAGATCAGGATCTATCGCTATTAGGCTTTATTCTCAATAGTGGGCGCTCA
CTTGTTATTGCAGTTAACAAATGGGATGGCATGACTGAAGAAGCCCGTGCGCAAGTAAAAGATATGCTGGACCTGCGTCT
TGGCTTTGTTGATTTTGCTCGCATTCACTTTATTTCAGCCTTGCATGGCAGCGGCGTCGGCAACCTGTTTGAATCGGTAC
AGGAAGCTTATGATTGCTCTACCAAGCGAGTGGGTACTTCCTTACTGACCCGTATTATGCAAATGGCAGAGGAAGACCAT
CAACCTCCGTTGGTCCGTGGTCGTCGCGTGAAGCTGAAATATGCCCATGCCGGTGGCTATAACCCGCCAATTGTAGTGAT
TCACGGTAATCAGGTGACTGACCTGTCAGATTCTTACAAACGCTATCTGATGAACTATTTCCGTCGTTCACTGAAAGTTA
TGGGGACGCCAATCCGCATTCAGTTTAAAGAGGGTGAGAACCCGTTTGCCGGTAAGCGCAACCCGCTGACACCTAATCAG
ATGCGTAAACGTAAACGTTTGATGTCTCATCTGAAAAAAGGTAAGTAA

Upstream 100 bases:

>100_bases
CTCCTGGGACTCAGGGGCCGTTTGTATTCTAAAAACTGCGCTGTTGAAGGTTCGATGCAGCGCTGTAACGCTTTGAAAAT
TAAGTAATGAGGCTTCAACA

Downstream 100 bases:

>100_bases
TTCAAGATAGAGCGGATACCCCGCGCTGAGGTTATTGGTAAAGTGCCCGCGACGGAGAGAACGGGCAGCAAGTAAAGACG
CCGGTTTCCCTGTATAAAAA

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA

Number of amino acids: Translated: 495; Mature: 495

Protein sequence:

>495_residues
MIPVIALVGRPNVGKSTLFNRLTHTRDALVADFPGLTRDRKYGRAEVEGHEFIVVDTGGIDGTEDGVETKMAGQSLLAIE
EADIVLFMVDARAGLMPADQGIAQHLRSREKATFLVANKTDGIDPDTATADFYSLGLGEVHAIAASHGRGVTQLIEDVMA
PYMDAEEPEVELTEEEENAAYWAEQEAQGEDVPPEDPEDDFDPRTLPIKLAIVGRPNVGKSTLTNRILGEDRVVVYDMPG
TTRDSIYIPMTRDDREYILIDTAGVRKRGKITETVEKFSVIKTLQAIEDSNVVLLVIDARDGISDQDLSLLGFILNSGRS
LVIAVNKWDGMTEEARAQVKDMLDLRLGFVDFARIHFISALHGSGVGNLFESVQEAYDCSTKRVGTSLLTRIMQMAEEDH
QPPLVRGRRVKLKYAHAGGYNPPIVVIHGNQVTDLSDSYKRYLMNYFRRSLKVMGTPIRIQFKEGENPFAGKRNPLTPNQ
MRKRKRLMSHLKKGK

Sequences:

>Translated_495_residues
MIPVIALVGRPNVGKSTLFNRLTHTRDALVADFPGLTRDRKYGRAEVEGHEFIVVDTGGIDGTEDGVETKMAGQSLLAIE
EADIVLFMVDARAGLMPADQGIAQHLRSREKATFLVANKTDGIDPDTATADFYSLGLGEVHAIAASHGRGVTQLIEDVMA
PYMDAEEPEVELTEEEENAAYWAEQEAQGEDVPPEDPEDDFDPRTLPIKLAIVGRPNVGKSTLTNRILGEDRVVVYDMPG
TTRDSIYIPMTRDDREYILIDTAGVRKRGKITETVEKFSVIKTLQAIEDSNVVLLVIDARDGISDQDLSLLGFILNSGRS
LVIAVNKWDGMTEEARAQVKDMLDLRLGFVDFARIHFISALHGSGVGNLFESVQEAYDCSTKRVGTSLLTRIMQMAEEDH
QPPLVRGRRVKLKYAHAGGYNPPIVVIHGNQVTDLSDSYKRYLMNYFRRSLKVMGTPIRIQFKEGENPFAGKRNPLTPNQ
MRKRKRLMSHLKKGK
>Mature_495_residues
MIPVIALVGRPNVGKSTLFNRLTHTRDALVADFPGLTRDRKYGRAEVEGHEFIVVDTGGIDGTEDGVETKMAGQSLLAIE
EADIVLFMVDARAGLMPADQGIAQHLRSREKATFLVANKTDGIDPDTATADFYSLGLGEVHAIAASHGRGVTQLIEDVMA
PYMDAEEPEVELTEEEENAAYWAEQEAQGEDVPPEDPEDDFDPRTLPIKLAIVGRPNVGKSTLTNRILGEDRVVVYDMPG
TTRDSIYIPMTRDDREYILIDTAGVRKRGKITETVEKFSVIKTLQAIEDSNVVLLVIDARDGISDQDLSLLGFILNSGRS
LVIAVNKWDGMTEEARAQVKDMLDLRLGFVDFARIHFISALHGSGVGNLFESVQEAYDCSTKRVGTSLLTRIMQMAEEDH
QPPLVRGRRVKLKYAHAGGYNPPIVVIHGNQVTDLSDSYKRYLMNYFRRSLKVMGTPIRIQFKEGENPFAGKRNPLTPNQ
MRKRKRLMSHLKKGK

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain

Homologues:

Organism=Escherichia coli, GI87082120, Length=495, Percent_Identity=81.2121212121212, Blast_Score=822, Evalue=0.0,
Organism=Escherichia coli, GI2367268, Length=91, Percent_Identity=37.3626373626374, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323665, Length=144, Percent_Identity=31.9444444444444, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DER_YERP3 (A7FFZ3)

Other databases:

- EMBL:   CP000720
- RefSeq:   YP_001400171.1
- ProteinModelPortal:   A7FFZ3
- SMR:   A7FFZ3
- STRING:   A7FFZ3
- GeneID:   5387789
- GenomeReviews:   CP000720_GR
- KEGG:   ypi:YpsIP31758_1190
- eggNOG:   COG1160
- HOGENOM:   HBG592135
- OMA:   TRDRTYQ
- ProtClustDB:   PRK00093
- BioCyc:   YPSE349747:YPSIP31758_1190-MONOMER
- GO:   GO:0005622
- HAMAP:   MF_00195
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- PIRSF:   PIRSF006485
- PRINTS:   PR00326
- TIGRFAMs:   TIGR03594
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01926 MMR_HSR1

EC number: NA

Molecular weight: Translated: 55007; Mature: 55007

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPVIALVGRPNVGKSTLFNRLTHTRDALVADFPGLTRDRKYGRAEVEGHEFIVVDTGGI
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCEEEEEECCCC
DGTEDGVETKMAGQSLLAIEEADIVLFMVDARAGLMPADQGIAQHLRSREKATFLVANKT
CCCCCCCHHHHCCCEEEEEECCCEEEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEEECC
DGIDPDTATADFYSLGLGEVHAIAASHGRGVTQLIEDVMAPYMDAEEPEVELTEEEENAA
CCCCCCCCCCHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCCC
YWAEQEAQGEDVPPEDPEDDFDPRTLPIKLAIVGRPNVGKSTLTNRILGEDRVVVYDMPG
EEECHHCCCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHCCCCCEEEEECCC
TTRDSIYIPMTRDDREYILIDTAGVRKRGKITETVEKFSVIKTLQAIEDSNVVLLVIDAR
CCCCCEEEEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECC
DGISDQDLSLLGFILNSGRSLVIAVNKWDGMTEEARAQVKDMLDLRLGFVDFARIHFISA
CCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LHGSGVGNLFESVQEAYDCSTKRVGTSLLTRIMQMAEEDHQPPLVRGRRVKLKYAHAGGY
HHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCC
NPPIVVIHGNQVTDLSDSYKRYLMNYFRRSLKVMGTPIRIQFKEGENPFAGKRNPLTPNQ
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHH
MRKRKRLMSHLKKGK
HHHHHHHHHHHHCCC
>Mature Secondary Structure
MIPVIALVGRPNVGKSTLFNRLTHTRDALVADFPGLTRDRKYGRAEVEGHEFIVVDTGGI
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCCEEEEEECCCC
DGTEDGVETKMAGQSLLAIEEADIVLFMVDARAGLMPADQGIAQHLRSREKATFLVANKT
CCCCCCCHHHHCCCEEEEEECCCEEEEEEECCCCCCCCHHHHHHHHHCCCCEEEEEEECC
DGIDPDTATADFYSLGLGEVHAIAASHGRGVTQLIEDVMAPYMDAEEPEVELTEEEENAA
CCCCCCCCCCHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCCC
YWAEQEAQGEDVPPEDPEDDFDPRTLPIKLAIVGRPNVGKSTLTNRILGEDRVVVYDMPG
EEECHHCCCCCCCCCCCCCCCCCCEEEEEEEEEECCCCCHHHHHHHHCCCCCEEEEECCC
TTRDSIYIPMTRDDREYILIDTAGVRKRGKITETVEKFSVIKTLQAIEDSNVVLLVIDAR
CCCCCEEEEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECC
DGISDQDLSLLGFILNSGRSLVIAVNKWDGMTEEARAQVKDMLDLRLGFVDFARIHFISA
CCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LHGSGVGNLFESVQEAYDCSTKRVGTSLLTRIMQMAEEDHQPPLVRGRRVKLKYAHAGGY
HHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCC
NPPIVVIHGNQVTDLSDSYKRYLMNYFRRSLKVMGTPIRIQFKEGENPFAGKRNPLTPNQ
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHH
MRKRKRLMSHLKKGK
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA