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The map label for this gene is bdlA [H]

Identifier: 218929604

GI number: 218929604

Start: 2824908

End: 2826155

Strand: Reverse

Name: bdlA [H]

Synonym: YPO2515

Alternate gene names: 218929604

Gene position: 2826155-2824908 (Counterclockwise)

Preceding gene: 218929607

Following gene: 218929595

Centisome position: 60.73

GC content: 47.76

Gene sequence:

>1248_bases
TTGACCTCAATTGATAACGCTGTCCCCATGATTATTTTTAAACCTGATGGCACGGTAGTCCAGGTGAATAAGTTATTTTT
AGCTGCCATGGGATACCAAAAGGATGAGGTGATTGGCAAACATCACAAAATATTTTGTGACCCACAATACGCTGCCAGTG
ACGCTTATCGCCGCCATTGGCAATTGCTTAATGAAGGGCGGCCAATTAGCGATAATATTAAGCGTATCCGCAAGGATGGC
AACGTAATTTGGCTACAGGGGACCTATACACCAGTCGTTGATCGCCAGGGTAATGTGATAGAAATCATTAAAATTGCCAG
TGATGTTACTGAGCGTATTTTACAATCGCAGGAACACCAAAGCTTGCTGGAGGCACTTAATCGCTCAATGGGGATGATTA
CCTTCACCCCCCAAGGCATTATTTTGGCTGCTAATGACAATTTATTAAATGTTATTGGGTATTCATTGGCAGACATTCAG
CATAAGTCTCATCAGATACTCTGTCTGCCTGAGTTTGCCCACTCCGAGGAATATCACCAGCACTGGCAGCGCTTGGCCCG
TGGCGAGTTTATTATCGGCCGCTTTGAACGCCTTAATCGCCGTGGTGAGCGGGTATGGCTGGAGGCCAGTTATAACCCGA
TCATGGATAATGAAGGGAACGTTCTAAAAGTGGTGAAAATTGCGCAGGATATTACCGCATTGATGCTGCAACAGGAGCAG
GAGGAGAACCTGATCCGCGATGTCCACCATTTATCATTGACCACTGACCGTTCCGCTTCACAGGGGGCTGAAATTGTTCA
GCAGGCAGTGCGTGGTATGCAAGAGGTGGAATCTATTGCACGTGAAACCTCCGATGTGGTCAGCGATTTGGGCCGTTGCT
CGCAAGAGATCGGCAGCATTGTGGAGGCTATCCGCAAGATTTCATCACAAACCAATTTATTGGCTATCAATGCCTCGATT
GAAGCGGCCCATGCCGGTGAACATGGGCGAGGGTTTTCTGTAGTCGCGAGTGAAGTCCGCTTGTTGGCTGATCAATCGCG
CAAGGCGGCAAGTGAAATCGAGCAAATGACTAAAACCATTCAGAATGGGGTTACCGCCGCGATCAAAGGGATGGGAACCT
GTGTTGAGCAGGCGGGGGGCGGGGTGATACTGACACAAGATGCTGGTGAGGTGATTAATCTGGTCAATGTGGGGATGCAA
GATGTGGTGAAATTAATGACCACTTTTTCTCAGGTAAAAAATCAGTGA

Upstream 100 bases:

>100_bases
TGAATCAGGAGAGCAGATTACCCCCTGGATCTGATTTCAGGCGTTGGGTGTGGATCACTATTGCACCGTTCGTTACACTC
ATGCCCCCTGGCGTGCCGAA

Downstream 100 bases:

>100_bases
GCACCAGTGTGACGAGCGGTGGCTATTTCTATCAAAGGATAGTGATAGTAAAGGGCCAATTGATCGCAAGGGGTAAGTGA
TCGTAAGGGATAAGTGAACG

Product: putative chemotactic transducer

Products: NA

Alternate protein names: Chemotaxis regulator BdlA [H]

Number of amino acids: Translated: 415; Mature: 414

Protein sequence:

>415_residues
MTSIDNAVPMIIFKPDGTVVQVNKLFLAAMGYQKDEVIGKHHKIFCDPQYAASDAYRRHWQLLNEGRPISDNIKRIRKDG
NVIWLQGTYTPVVDRQGNVIEIIKIASDVTERILQSQEHQSLLEALNRSMGMITFTPQGIILAANDNLLNVIGYSLADIQ
HKSHQILCLPEFAHSEEYHQHWQRLARGEFIIGRFERLNRRGERVWLEASYNPIMDNEGNVLKVVKIAQDITALMLQQEQ
EENLIRDVHHLSLTTDRSASQGAEIVQQAVRGMQEVESIARETSDVVSDLGRCSQEIGSIVEAIRKISSQTNLLAINASI
EAAHAGEHGRGFSVVASEVRLLADQSRKAASEIEQMTKTIQNGVTAAIKGMGTCVEQAGGGVILTQDAGEVINLVNVGMQ
DVVKLMTTFSQVKNQ

Sequences:

>Translated_415_residues
MTSIDNAVPMIIFKPDGTVVQVNKLFLAAMGYQKDEVIGKHHKIFCDPQYAASDAYRRHWQLLNEGRPISDNIKRIRKDG
NVIWLQGTYTPVVDRQGNVIEIIKIASDVTERILQSQEHQSLLEALNRSMGMITFTPQGIILAANDNLLNVIGYSLADIQ
HKSHQILCLPEFAHSEEYHQHWQRLARGEFIIGRFERLNRRGERVWLEASYNPIMDNEGNVLKVVKIAQDITALMLQQEQ
EENLIRDVHHLSLTTDRSASQGAEIVQQAVRGMQEVESIARETSDVVSDLGRCSQEIGSIVEAIRKISSQTNLLAINASI
EAAHAGEHGRGFSVVASEVRLLADQSRKAASEIEQMTKTIQNGVTAAIKGMGTCVEQAGGGVILTQDAGEVINLVNVGMQ
DVVKLMTTFSQVKNQ
>Mature_414_residues
TSIDNAVPMIIFKPDGTVVQVNKLFLAAMGYQKDEVIGKHHKIFCDPQYAASDAYRRHWQLLNEGRPISDNIKRIRKDGN
VIWLQGTYTPVVDRQGNVIEIIKIASDVTERILQSQEHQSLLEALNRSMGMITFTPQGIILAANDNLLNVIGYSLADIQH
KSHQILCLPEFAHSEEYHQHWQRLARGEFIIGRFERLNRRGERVWLEASYNPIMDNEGNVLKVVKIAQDITALMLQQEQE
ENLIRDVHHLSLTTDRSASQGAEIVQQAVRGMQEVESIARETSDVVSDLGRCSQEIGSIVEAIRKISSQTNLLAINASIE
AAHAGEHGRGFSVVASEVRLLADQSRKAASEIEQMTKTIQNGVTAAIKGMGTCVEQAGGGVILTQDAGEVINLVNVGMQD
VVKLMTTFSQVKNQ

Specific function: Essential for biofilm dispersion by sensing environmental cues. May be involved in sensing and transducing signals within cells, resulting in the modulation of c-di-GMP levels, swimming motility and adhesiveness of the bacterial cell surface [H]

COG id: COG2202

COG function: function code T; FOG: PAS/PAC domain

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=134, Percent_Identity=40.2985074626866, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1788195, Length=168, Percent_Identity=31.547619047619, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1789453, Length=106, Percent_Identity=40.5660377358491, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788194, Length=96, Percent_Identity=43.75, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787690, Length=74, Percent_Identity=55.4054054054054, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00015 MCPsignal; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: NA

Molecular weight: Translated: 46124; Mature: 45993

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSIDNAVPMIIFKPDGTVVQVNKLFLAAMGYQKDEVIGKHHKIFCDPQYAASDAYRRHW
CCCCCCCCCEEEECCCCCEEEHHHHHHHHHCCCHHHHCCCCCEEEECCCHHHHHHHHHHH
QLLNEGRPISDNIKRIRKDGNVIWLQGTYTPVVDRQGNVIEIIKIASDVTERILQSQEHQ
HHHHCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHH
SLLEALNRSMGMITFTPQGIILAANDNLLNVIGYSLADIQHKSHQILCLPEFAHSEEYHQ
HHHHHHHHCCCEEEECCCCEEEEECCCCHHHHHHHHHHHCCCCCEEEEECCHHCCHHHHH
HWQRLARGEFIIGRFERLNRRGERVWLEASYNPIMDNEGNVLKVVKIAQDITALMLQQEQ
HHHHHHCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCEEHHHHHHHHHHHHHHHHHH
EENLIRDVHHLSLTTDRSASQGAEIVQQAVRGMQEVESIARETSDVVSDLGRCSQEIGSI
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VEAIRKISSQTNLLAINASIEAAHAGEHGRGFSVVASEVRLLADQSRKAASEIEQMTKTI
HHHHHHHCCCCCEEEEECCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QNGVTAAIKGMGTCVEQAGGGVILTQDAGEVINLVNVGMQDVVKLMTTFSQVKNQ
HHCHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TSIDNAVPMIIFKPDGTVVQVNKLFLAAMGYQKDEVIGKHHKIFCDPQYAASDAYRRHW
CCCCCCCCEEEECCCCCEEEHHHHHHHHHCCCHHHHCCCCCEEEECCCHHHHHHHHHHH
QLLNEGRPISDNIKRIRKDGNVIWLQGTYTPVVDRQGNVIEIIKIASDVTERILQSQEHQ
HHHHCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHH
SLLEALNRSMGMITFTPQGIILAANDNLLNVIGYSLADIQHKSHQILCLPEFAHSEEYHQ
HHHHHHHHCCCEEEECCCCEEEEECCCCHHHHHHHHHHHCCCCCEEEEECCHHCCHHHHH
HWQRLARGEFIIGRFERLNRRGERVWLEASYNPIMDNEGNVLKVVKIAQDITALMLQQEQ
HHHHHHCCCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCEEHHHHHHHHHHHHHHHHHH
EENLIRDVHHLSLTTDRSASQGAEIVQQAVRGMQEVESIARETSDVVSDLGRCSQEIGSI
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VEAIRKISSQTNLLAINASIEAAHAGEHGRGFSVVASEVRLLADQSRKAASEIEQMTKTI
HHHHHHHCCCCCEEEEECCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QNGVTAAIKGMGTCVEQAGGGVILTQDAGEVINLVNVGMQDVVKLMTTFSQVKNQ
HHCHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]