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The map label for this gene is ynaJ [H]

Identifier: 218928382

GI number: 218928382

Start: 1386168

End: 1387664

Strand: Reverse

Name: ynaJ [H]

Synonym: YPO1226

Alternate gene names: 218928382

Gene position: 1387664-1386168 (Counterclockwise)

Preceding gene: 218928384

Following gene: 218928381

Centisome position: 29.82

GC content: 47.36

Gene sequence:

>1497_bases
TTGGCTTACGGGAGTGCTAACTTGCTGGGCAGTGGGGCACTCGCCATTAGTGGTGCCTGGCTGATGTACTTCTACACAAC
GTTTTGCGGACTTTCTGTTGTAGAAGCAGCCACTATCTTTTCAATCGCCAGTATTATTGATGCCATCAGTAACCCGGTAA
TGGGTTATATCACGGATAACTTCTACAATACCCGTTTGGGCCGTATCTTCGGGCGTCGTCGCTTCTTTATCTTACTGGGT
ATCCCACTCGTGTTGGTCTATCCAATGCTGTGGATGAGTGGTTTTGGTTTCTGGTATTACCTACTGACCTATGCGCTGTT
TGAATTAATTTACACCTCCATCATGGTGCCTTATGAAACACTGGCTACCGAGATGACAACCGATTTTGCCAAACGCTCTA
AACTGACAGGTTCTAAAGCAATCTTCGGCAAAGTAGCGAACTTCCTGGCCGCTTTCATTCCAGGTCAATTCATTGCAATT
TATGGCAAAGATTCCGCAACCCCCTTCTTATATACCGGTATCGCTTATGGTCTGATTATGTGCTGCGCCATGATTTGGCT
TTACAGCTCATCATGGGAGCGTCCAGCCAGTGAAGTGGTCAGGGAAACCACCAGTAGTTTAGGTCAGGCACTGAAAAAGC
TGTGTGTTGATATGGCATCGACCTTCCATCTGCGCATTTTCCGCAAGCATCTGGGGATGTATCTGTTCGGTTTTGGTGCT
GAATGGTTGTTCGCATCCGCATTTACCTACTTTATTATTTTTGGCTTGGGACAAGATGCCGCATTGGTTTCGCAGCTCAA
TAGCTTCAGTTCGATTATGCAGCTCATCTCCACCGCTATTTTTATTGGCATCTGCGTAAAAATGGGTTTCGCTCGTCCCT
TCCGTATTGCTCTGCAAGTGGTGATTGTCAGCGTGGTTGCCTACGCAGCACTGTATTTCACCGGTTGGTCTGAAACCACG
ACCGTTATCGTCTTATTCTGCATTACCGCTGTTTTCGGTTTAAGTACTGGTGGGATCTACTATATTCCATGGACAGTTTA
TACCTTCCTGGCCGATGTAGACGAAGTCTTGACCGGGCGTCGCCGTGAAGGAATTTATGCTGGCGCGATGACATTCGCCG
GGAAAATGGTACGTTCGATTATTGTCTTTGCCATGGGCTGGACGTTAAGCCGCTTTGGTTTTGTTTCTGGTCAATCCAGT
CAGCCAGAAATTGCTGTGCAAGCCATCGTGGGTGTCTTTGCCATAGGGGTTATCTCACTGGCATTAGTTGCTATTTACTA
CACCACACAGATGAAACTGGATCGCAAAAATCACAGCATTTTACTGGAAGAAATTGAGCGTATTAAAAATGGCGGTGCCA
TGGCAGATATCCCCGCTCATGCCAGAGCCGTCGCGGAAGAACTGACGGGGTGGAAATATGAACAATGTTGGGGCAATAAC
CCCCTCGGCGTCAAAGAGTCGCCAACCGTCATACCCAAACCGGTTACTGAAAGTTAA

Upstream 100 bases:

>100_bases
TATACCGCTATAAAGAAAACAGTTATTCATTATAAATGAAACATTGTTTTAATTTGAGGTGGCGGTAAACATGAGTAAAC
AGATTTCAACAAGGCATACG

Downstream 100 bases:

>100_bases
TTAATTTCTGGTCGTGACCACAAACCGCACCGGTCCCGCCAGTGCGGTTTTTGCTTCTCCCTTCCCTGAACATGAATGGG
TAGATAAAATATCGGCGTTG

Product: putative transport protein

Products: Proton [Cytoplasm]; Glucuronides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 498; Mature: 497

Protein sequence:

>498_residues
MAYGSANLLGSGALAISGAWLMYFYTTFCGLSVVEAATIFSIASIIDAISNPVMGYITDNFYNTRLGRIFGRRRFFILLG
IPLVLVYPMLWMSGFGFWYYLLTYALFELIYTSIMVPYETLATEMTTDFAKRSKLTGSKAIFGKVANFLAAFIPGQFIAI
YGKDSATPFLYTGIAYGLIMCCAMIWLYSSSWERPASEVVRETTSSLGQALKKLCVDMASTFHLRIFRKHLGMYLFGFGA
EWLFASAFTYFIIFGLGQDAALVSQLNSFSSIMQLISTAIFIGICVKMGFARPFRIALQVVIVSVVAYAALYFTGWSETT
TVIVLFCITAVFGLSTGGIYYIPWTVYTFLADVDEVLTGRRREGIYAGAMTFAGKMVRSIIVFAMGWTLSRFGFVSGQSS
QPEIAVQAIVGVFAIGVISLALVAIYYTTQMKLDRKNHSILLEEIERIKNGGAMADIPAHARAVAEELTGWKYEQCWGNN
PLGVKESPTVIPKPVTES

Sequences:

>Translated_498_residues
MAYGSANLLGSGALAISGAWLMYFYTTFCGLSVVEAATIFSIASIIDAISNPVMGYITDNFYNTRLGRIFGRRRFFILLG
IPLVLVYPMLWMSGFGFWYYLLTYALFELIYTSIMVPYETLATEMTTDFAKRSKLTGSKAIFGKVANFLAAFIPGQFIAI
YGKDSATPFLYTGIAYGLIMCCAMIWLYSSSWERPASEVVRETTSSLGQALKKLCVDMASTFHLRIFRKHLGMYLFGFGA
EWLFASAFTYFIIFGLGQDAALVSQLNSFSSIMQLISTAIFIGICVKMGFARPFRIALQVVIVSVVAYAALYFTGWSETT
TVIVLFCITAVFGLSTGGIYYIPWTVYTFLADVDEVLTGRRREGIYAGAMTFAGKMVRSIIVFAMGWTLSRFGFVSGQSS
QPEIAVQAIVGVFAIGVISLALVAIYYTTQMKLDRKNHSILLEEIERIKNGGAMADIPAHARAVAEELTGWKYEQCWGNN
PLGVKESPTVIPKPVTES
>Mature_497_residues
AYGSANLLGSGALAISGAWLMYFYTTFCGLSVVEAATIFSIASIIDAISNPVMGYITDNFYNTRLGRIFGRRRFFILLGI
PLVLVYPMLWMSGFGFWYYLLTYALFELIYTSIMVPYETLATEMTTDFAKRSKLTGSKAIFGKVANFLAAFIPGQFIAIY
GKDSATPFLYTGIAYGLIMCCAMIWLYSSSWERPASEVVRETTSSLGQALKKLCVDMASTFHLRIFRKHLGMYLFGFGAE
WLFASAFTYFIIFGLGQDAALVSQLNSFSSIMQLISTAIFIGICVKMGFARPFRIALQVVIVSVVAYAALYFTGWSETTT
VIVLFCITAVFGLSTGGIYYIPWTVYTFLADVDEVLTGRRREGIYAGAMTFAGKMVRSIIVFAMGWTLSRFGFVSGQSSQ
PEIAVQAIVGVFAIGVISLALVAIYYTTQMKLDRKNHSILLEEIERIKNGGAMADIPAHARAVAEELTGWKYEQCWGNNP
LGVKESPTVIPKPVTES

Specific function: Unknown

COG id: COG2211

COG function: function code G; Na+/melibiose symporter and related transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:galactoside symporter (TC 2.A.2) family [H]

Homologues:

Organism=Escherichia coli, GI1787902, Length=466, Percent_Identity=21.244635193133, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1786466, Length=449, Percent_Identity=23.162583518931, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI87082306, Length=448, Percent_Identity=23.6607142857143, Blast_Score=65, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001927
- InterPro:   IPR018043 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 55021; Mature: 54890

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYGSANLLGSGALAISGAWLMYFYTTFCGLSVVEAATIFSIASIIDAISNPVMGYITDN
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
FYNTRLGRIFGRRRFFILLGIPLVLVYPMLWMSGFGFWYYLLTYALFELIYTSIMVPYET
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
LATEMTTDFAKRSKLTGSKAIFGKVANFLAAFIPGQFIAIYGKDSATPFLYTGIAYGLIM
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHH
CCAMIWLYSSSWERPASEVVRETTSSLGQALKKLCVDMASTFHLRIFRKHLGMYLFGFGA
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
EWLFASAFTYFIIFGLGQDAALVSQLNSFSSIMQLISTAIFIGICVKMGFARPFRIALQV
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
VIVSVVAYAALYFTGWSETTTVIVLFCITAVFGLSTGGIYYIPWTVYTFLADVDEVLTGR
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHCCC
RREGIYAGAMTFAGKMVRSIIVFAMGWTLSRFGFVSGQSSQPEIAVQAIVGVFAIGVISL
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
ALVAIYYTTQMKLDRKNHSILLEEIERIKNGGAMADIPAHARAVAEELTGWKYEQCWGNN
HHHHHHHHHHHEECCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHCCCC
PLGVKESPTVIPKPVTES
CCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AYGSANLLGSGALAISGAWLMYFYTTFCGLSVVEAATIFSIASIIDAISNPVMGYITDN
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
FYNTRLGRIFGRRRFFILLGIPLVLVYPMLWMSGFGFWYYLLTYALFELIYTSIMVPYET
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
LATEMTTDFAKRSKLTGSKAIFGKVANFLAAFIPGQFIAIYGKDSATPFLYTGIAYGLIM
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHH
CCAMIWLYSSSWERPASEVVRETTSSLGQALKKLCVDMASTFHLRIFRKHLGMYLFGFGA
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
EWLFASAFTYFIIFGLGQDAALVSQLNSFSSIMQLISTAIFIGICVKMGFARPFRIALQV
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
VIVSVVAYAALYFTGWSETTTVIVLFCITAVFGLSTGGIYYIPWTVYTFLADVDEVLTGR
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHCCC
RREGIYAGAMTFAGKMVRSIIVFAMGWTLSRFGFVSGQSSQPEIAVQAIVGVFAIGVISL
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
ALVAIYYTTQMKLDRKNHSILLEEIERIKNGGAMADIPAHARAVAEELTGWKYEQCWGNN
HHHHHHHHHHHEECCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHCCCC
PLGVKESPTVIPKPVTES
CCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; Glucuronides [Periplasm] [C]

Specific reaction: Proton [Periplasm] + Glucuronides [Periplasm] = Proton [Cytoplasm] + Glucuronides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]