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The map label for this gene is rcsB [H]

Identifier: 218928377

GI number: 218928377

Start: 1376533

End: 1377186

Strand: Reverse

Name: rcsB [H]

Synonym: YPO1218

Alternate gene names: 218928377

Gene position: 1377186-1376533 (Counterclockwise)

Preceding gene: 218928378

Following gene: 218928374

Centisome position: 29.59

GC content: 39.6

Gene sequence:

>654_bases
ATGAACAACCTTAATGTAATTATTGCTGATGACCATCCAATTGTTTTGTTTGGCATCCGAAAGTCGCTTGAGCAAATTGA
ATGGGTAAACGTTGTCGGAGAATTTGAAGACTCCACTGCGCTTATTAACAATTTGTCCAAACTTGATGCCAACGTGCTAA
TTACTGACCTCTCTATGCCAGGGGATAAGTATGGTGATGGCATCACATTAATCAAATATATAAAACGACATTATCCAGAT
TTGGCTATAATTGTCTTAACTATGAATAATAATCCGGCTATCTTAAGTTCTGTCTTGGACTTAGATATCGACGGAATAGT
ATTGAAACAGGGCGCACCCGCTGACTTACCTAAGGCATTGGCCGCATTACAAAAAGGGAAGAAATTCACTCCTGAAAGCG
TAGCCAAACTACTCGAAAAAATCAGTGCCAATGGTTACGGTGACAAGCGTTTGTCACCAAAAGAAAGTGAAGTTTTGCGA
CTCTTTGCTGAAGGTTTTCTGGTAACAGAAATTGCCAGAAAACTTAACCGCAGTATCAAGACCATTAGCAGCCAGAAGAA
ATCTGCAATGCTAAAGCTGGGCGTTGATAACGATATCGCTTTGCTAAATTATCTTTCGTCTGTGACAATTAGCCAAGTGG
ATAAAGAACTGTAA

Upstream 100 bases:

>100_bases
AACAGCATATCGCAGATGGCGATCGGTTGAAGATCGAAAATAGCATCAGTCAGATTGATTTTTTCATCACCAGACTGTTG
CAGGAAGGTAACCCATAACC

Downstream 100 bases:

>100_bases
TTTTTGCCCCGCTCGACTCTCAAGCCCAGTTTTGCTCTGCAATACTGGGCTTATTAATTAATGAAATCTAACGTGATCGC
CGTACTTGGTCACTGTAGTA

Product: transcriptional regulator RcsB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MNNLNVIIADDHPIVLFGIRKSLEQIEWVNVVGEFEDSTALINNLSKLDANVLITDLSMPGDKYGDGITLIKYIKRHYPD
LAIIVLTMNNNPAILSSVLDLDIDGIVLKQGAPADLPKALAALQKGKKFTPESVAKLLEKISANGYGDKRLSPKESEVLR
LFAEGFLVTEIARKLNRSIKTISSQKKSAMLKLGVDNDIALLNYLSSVTISQVDKEL

Sequences:

>Translated_217_residues
MNNLNVIIADDHPIVLFGIRKSLEQIEWVNVVGEFEDSTALINNLSKLDANVLITDLSMPGDKYGDGITLIKYIKRHYPD
LAIIVLTMNNNPAILSSVLDLDIDGIVLKQGAPADLPKALAALQKGKKFTPESVAKLLEKISANGYGDKRLSPKESEVLR
LFAEGFLVTEIARKLNRSIKTISSQKKSAMLKLGVDNDIALLNYLSSVTISQVDKEL
>Mature_217_residues
MNNLNVIIADDHPIVLFGIRKSLEQIEWVNVVGEFEDSTALINNLSKLDANVLITDLSMPGDKYGDGITLIKYIKRHYPD
LAIIVLTMNNNPAILSSVLDLDIDGIVLKQGAPADLPKALAALQKGKKFTPESVAKLLEKISANGYGDKRLSPKESEVLR
LFAEGFLVTEIARKLNRSIKTISSQKKSAMLKLGVDNDIALLNYLSSVTISQVDKEL

Specific function: Also stimulates ftsZ expression. This suggests that rcsB is a regulator implicated in the regulation of more than one cellular function [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788546, Length=216, Percent_Identity=91.2037037037037, Blast_Score=400, Evalue=1e-113,
Organism=Escherichia coli, GI1788222, Length=204, Percent_Identity=27.9411764705882, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1788521, Length=200, Percent_Identity=30, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI1790102, Length=203, Percent_Identity=30.0492610837438, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1786747, Length=206, Percent_Identity=27.6699029126214, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1788712, Length=191, Percent_Identity=26.1780104712042, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23815; Mature: 23815

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNLNVIIADDHPIVLFGIRKSLEQIEWVNVVGEFEDSTALINNLSKLDANVLITDLSMP
CCCCEEEEECCCCEEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEEECCCC
GDKYGDGITLIKYIKRHYPDLAIIVLTMNNNPAILSSVLDLDIDGIVLKQGAPADLPKAL
CCCCCCCHHHHHHHHHHCCCEEEEEEEECCCHHHHHHHHHCCCCCEEECCCCCCCHHHHH
AALQKGKKFTPESVAKLLEKISANGYGDKRLSPKESEVLRLFAEGFLVTEIARKLNRSIK
HHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TISSQKKSAMLKLGVDNDIALLNYLSSVTISQVDKEL
HHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNNLNVIIADDHPIVLFGIRKSLEQIEWVNVVGEFEDSTALINNLSKLDANVLITDLSMP
CCCCEEEEECCCCEEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEEECCCC
GDKYGDGITLIKYIKRHYPDLAIIVLTMNNNPAILSSVLDLDIDGIVLKQGAPADLPKAL
CCCCCCCHHHHHHHHHHCCCEEEEEEEECCCHHHHHHHHHCCCCCEEECCCCCCCHHHHH
AALQKGKKFTPESVAKLLEKISANGYGDKRLSPKESEVLRLFAEGFLVTEIARKLNRSIK
HHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TISSQKKSAMLKLGVDNDIALLNYLSSVTISQVDKEL
HHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]