Click here to switch to the map view.

The map label for this gene is ubiG [H]

Identifier: 218928374

GI number: 218928374

Start: 1369739

End: 1370467

Strand: Reverse

Name: ubiG [H]

Synonym: YPO1215

Alternate gene names: 218928374

Gene position: 1370467-1369739 (Counterclockwise)

Preceding gene: 218928377

Following gene: 218928373

Centisome position: 29.45

GC content: 49.93

Gene sequence:

>729_bases
ATGCGAGCCAAAACGACAAGCCGCCATCATAACGTTGATGAGCAAGAAATCGCTAAATTTGAAGCTGTTGCCTCCCGCTG
GTGGGATTTAGAAGGCGAATTTAAGCCTCTCCACCGTATTAATCCCCTGCGCCTCAACTATATCTTGCAGCGCTCAGGCG
GTATTTTTGAGAAAAAAGTGCTGGATGTCGGCTGTGGTGGCGGGATTCTGGCCGAAAGCATGGCGCGTGAAGGCGCGCAA
GTGACTGGCCTGGATATGGGCTACGAGCCGCTACAAGTTGCGCGTCTGCATGCTCTGGAAACTGGCGTCAAACTCGAGTA
TGTGCAGGAAACCGTTGAAAATCATGCGCAGCAACACCCGCAACACTACGATGTAGTGACCTGCATGGAGATGCTCGAAC
ATGTACCGGATCCTGCTTCCGTGGTACGGGCCTGTGCACAATTGGTCAAACCGGGTGGGCATGTTTTCTTTTCGACCATT
AACCGTAATACCAAGTCTTGGCTAATGGCCGTCGTTGGTGCCGAATATCTATTGAAAATGGTGCCTAAAGGCACACATGA
TGCGAAAAAGTTTATCCGCCCGTCAGAGTTAATAGGCTGGGTAGATCAAACGCCATTGCTTGAACGCCATATTATCGGGC
TACATTACAACCCGATCACCGACCATTTTAAGCTTGGCCGCAATGTTGATGTAAATTATATGGTGCATACACAACGGGAC
AGCGAATAG

Upstream 100 bases:

>100_bases
CCACAGCTCACGCCCTCGGCAACGTCGAGCACGAAGGCTAATACAAAAGATGGGGAACATGTATAATCCGCGCAAAGAAA
CAAAACAGTGAGAACCCATC

Downstream 100 bases:

>100_bases
ATCAGCCGTAGAACCCACTGGGAGCAGGGCTAAGCACCTGCTCTTCCTGGCTTTTCCCCCTCGCAGTTATCCCTTTATAT
GCTGTTAATCGCCAGATCAG

Product: 3-demethylubiquinone-9 3-methyltransferase

Products: NA

Alternate protein names: 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase; DHHB methyltransferase [H]

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MRAKTTSRHHNVDEQEIAKFEAVASRWWDLEGEFKPLHRINPLRLNYILQRSGGIFEKKVLDVGCGGGILAESMAREGAQ
VTGLDMGYEPLQVARLHALETGVKLEYVQETVENHAQQHPQHYDVVTCMEMLEHVPDPASVVRACAQLVKPGGHVFFSTI
NRNTKSWLMAVVGAEYLLKMVPKGTHDAKKFIRPSELIGWVDQTPLLERHIIGLHYNPITDHFKLGRNVDVNYMVHTQRD
SE

Sequences:

>Translated_242_residues
MRAKTTSRHHNVDEQEIAKFEAVASRWWDLEGEFKPLHRINPLRLNYILQRSGGIFEKKVLDVGCGGGILAESMAREGAQ
VTGLDMGYEPLQVARLHALETGVKLEYVQETVENHAQQHPQHYDVVTCMEMLEHVPDPASVVRACAQLVKPGGHVFFSTI
NRNTKSWLMAVVGAEYLLKMVPKGTHDAKKFIRPSELIGWVDQTPLLERHIIGLHYNPITDHFKLGRNVDVNYMVHTQRD
SE
>Mature_242_residues
MRAKTTSRHHNVDEQEIAKFEAVASRWWDLEGEFKPLHRINPLRLNYILQRSGGIFEKKVLDVGCGGGILAESMAREGAQ
VTGLDMGYEPLQVARLHALETGVKLEYVQETVENHAQQHPQHYDVVTCMEMLEHVPDPASVVRACAQLVKPGGHVFFSTI
NRNTKSWLMAVVGAEYLLKMVPKGTHDAKKFIRPSELIGWVDQTPLLERHIIGLHYNPITDHFKLGRNVDVNYMVHTQRD
SE

Specific function: Ubiquinone biosynthesis. [C]

COG id: COG2227

COG function: function code H; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiG/COQ3 family [H]

Homologues:

Organism=Homo sapiens, GI118600965, Length=248, Percent_Identity=32.258064516129, Blast_Score=158, Evalue=4e-39,
Organism=Escherichia coli, GI1788564, Length=238, Percent_Identity=80.2521008403361, Blast_Score=411, Evalue=1e-116,
Organism=Caenorhabditis elegans, GI115533050, Length=241, Percent_Identity=31.9502074688797, Blast_Score=129, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6324476, Length=250, Percent_Identity=31.6, Blast_Score=130, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24585589, Length=235, Percent_Identity=33.1914893617021, Blast_Score=142, Evalue=3e-34,
Organism=Drosophila melanogaster, GI281365311, Length=260, Percent_Identity=30.3846153846154, Blast_Score=138, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216
- InterPro:   IPR010233 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: =2.1.1.64 [H]

Molecular weight: Translated: 27467; Mature: 27467

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAKTTSRHHNVDEQEIAKFEAVASRWWDLEGEFKPLHRINPLRLNYILQRSGGIFEKKV
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHCCCCCHHHHH
LDVGCGGGILAESMAREGAQVTGLDMGYEPLQVARLHALETGVKLEYVQETVENHAQQHP
HCCCCCCHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
QHYDVVTCMEMLEHVPDPASVVRACAQLVKPGGHVFFSTINRNTKSWLMAVVGAEYLLKM
CHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHH
VPKGTHDAKKFIRPSELIGWVDQTPLLERHIIGLHYNPITDHFKLGRNVDVNYMVHTQRD
CCCCCHHHHHHCCHHHHHCCCCCCCHHHHHEEEEECCCCCHHHHCCCCCCEEEEEECCCC
SE
CC
>Mature Secondary Structure
MRAKTTSRHHNVDEQEIAKFEAVASRWWDLEGEFKPLHRINPLRLNYILQRSGGIFEKKV
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHCCCCHHHHHHHHCCCCCHHHHH
LDVGCGGGILAESMAREGAQVTGLDMGYEPLQVARLHALETGVKLEYVQETVENHAQQHP
HCCCCCCHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
QHYDVVTCMEMLEHVPDPASVVRACAQLVKPGGHVFFSTINRNTKSWLMAVVGAEYLLKM
CHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHH
VPKGTHDAKKFIRPSELIGWVDQTPLLERHIIGLHYNPITDHFKLGRNVDVNYMVHTQRD
CCCCCHHHHHHCCHHHHHCCCCCCCHHHHHEEEEECCCCCHHHHCCCCCCEEEEEECCCC
SE
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA