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The map label for this gene is katA [H]

Identifier: 218928366

GI number: 218928366

Start: 1359182

End: 1360624

Strand: Reverse

Name: katA [H]

Synonym: YPO1207

Alternate gene names: 218928366

Gene position: 1360624-1359182 (Counterclockwise)

Preceding gene: 218928368

Following gene: 218928364

Centisome position: 29.24

GC content: 49.41

Gene sequence:

>1443_bases
ATGATGAGCAAGAAGAAAGGATTAACCACCGCGGCAGGCGCTCCCGTTGTCGATAATAATAATGTTATTACGGCTGGCCG
CCGTGGCCCGATGCTACTGCAAGATGTTTGGTTCCTGGAAAAATTAGCCCATTTTGACCGTGAAGTGATCCCTGAGCGCC
GCATGCATGCTAAAGGCTCCGGTGCATACGGTACGTTCACCGTGACTCATGATATTACCCAATATACTCGCGCAAAAATT
TTCTCAGAGATCGGTAAAAAAACAGACATGTTTGTCCGCTTCTCCACTGTGGCCGGTGAACGCGGTGCTGCAGATGCTGA
ACGTGATATCCGTGGTTTTGCCATGAAGTTTTATACCGAGGAAGGCAACTGGGATTTGGTTGGTAACGATACACCGGTCT
TCTATTTACGTGATCCACTGAAGTTCCCGGACCTGAACCACGTGGTCAAACGCGACCCTCGTACCAACCTGCGTAACCCG
GTTTATAAATGGGATTTCTTCTCTCAACTGCCAGAGGCGCTGCATCAGTTAACCATCGATTTCAGTGACCGTGGCTTGCC
AAAATCTTACCGTCATATGCACGGTTTCGGTAGCCATACCTTTAGCCTAATCAATGCCAATAATGAACGTTTTTGGGTTA
AATTCCATTTCCGTTGCCAGCAAGGCATTGAAAACCTGATGGACGATGAAGCCGAAAAACTGATTGGTTCTGATAGAGAA
AGCTCGCAGCGTGATCTGTATGAAGCGATTGAGCGCGGTGACTTCCCGCGTTGGAAACTACAGATTCAGGTAATGCCGGA
GCACGAAGCATCACAAACACCTTATAACCCATTTGATCTGACTAAAGTCTGGCCGCACGGTGATTACCCGCTGATCGATG
TCGGCTACTTCGAATTGAATCGCAACCCGGAAAACTACTTCGCTGAAGTGGAACAATCCTCATTCAATCCAGCTAACGTT
GTCCCTGGGATCAGTTTCTCCCCAGACCGCATGTTACAAGGCCGCCTGTTCTCATACGGTGATGCCGCCCGCTATCGTTT
AGGGGTTAACCATCATCAGATCCCGGTGAACAGTGCTAAATGTCCGTTCCATAATTATCATCGTGACGGCGCAATGCGCG
TTGATGGTAACAGTGGTAATGGCGCAACCTATGAGCCAAACAGCTTTGGCCTGTTCCAAGAACAGCCTGATTTCAGCGAA
CCGCCACTGACATTGGAAGGGGCGGCAGATCATTGGAATCACCGCGAAGACACCGACTATTTCTCTCAACCACGGGCGCT
GTTTAACCTGCTCAGTGAAGAAGAGCATCAACGCATGTTCACCCGTATTGCGGGTGAGTTATCGCAAGTTCCTGAAGCTA
TCCAACGCCGCCAGATAGCGTTGTTTACGCAGGTTGACCCGGCTTATGGCGCCGGTGTGAAAAAAGCACTTGGCCTGAAT
TAA

Upstream 100 bases:

>100_bases
CGTGTTTTTGTTAAAATTATTATCTTGTCAATCACGTTTTTGACGCGATATCACGCTTAAACCCAAAACCGCAATCAATT
CAACAGCCATACTGGAGAAC

Downstream 100 bases:

>100_bases
ACCCGATCAGCCCCTTTGAACTGCACCCCAAATGTTGGATAACCCCCTGACATTTGGAGGTGTATTTTTATGGCTTATCC
CGTGTCTTCCTAACCCGCTT

Product: catalase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 480; Mature: 480

Protein sequence:

>480_residues
MMSKKKGLTTAAGAPVVDNNNVITAGRRGPMLLQDVWFLEKLAHFDREVIPERRMHAKGSGAYGTFTVTHDITQYTRAKI
FSEIGKKTDMFVRFSTVAGERGAADAERDIRGFAMKFYTEEGNWDLVGNDTPVFYLRDPLKFPDLNHVVKRDPRTNLRNP
VYKWDFFSQLPEALHQLTIDFSDRGLPKSYRHMHGFGSHTFSLINANNERFWVKFHFRCQQGIENLMDDEAEKLIGSDRE
SSQRDLYEAIERGDFPRWKLQIQVMPEHEASQTPYNPFDLTKVWPHGDYPLIDVGYFELNRNPENYFAEVEQSSFNPANV
VPGISFSPDRMLQGRLFSYGDAARYRLGVNHHQIPVNSAKCPFHNYHRDGAMRVDGNSGNGATYEPNSFGLFQEQPDFSE
PPLTLEGAADHWNHREDTDYFSQPRALFNLLSEEEHQRMFTRIAGELSQVPEAIQRRQIALFTQVDPAYGAGVKKALGLN

Sequences:

>Translated_480_residues
MMSKKKGLTTAAGAPVVDNNNVITAGRRGPMLLQDVWFLEKLAHFDREVIPERRMHAKGSGAYGTFTVTHDITQYTRAKI
FSEIGKKTDMFVRFSTVAGERGAADAERDIRGFAMKFYTEEGNWDLVGNDTPVFYLRDPLKFPDLNHVVKRDPRTNLRNP
VYKWDFFSQLPEALHQLTIDFSDRGLPKSYRHMHGFGSHTFSLINANNERFWVKFHFRCQQGIENLMDDEAEKLIGSDRE
SSQRDLYEAIERGDFPRWKLQIQVMPEHEASQTPYNPFDLTKVWPHGDYPLIDVGYFELNRNPENYFAEVEQSSFNPANV
VPGISFSPDRMLQGRLFSYGDAARYRLGVNHHQIPVNSAKCPFHNYHRDGAMRVDGNSGNGATYEPNSFGLFQEQPDFSE
PPLTLEGAADHWNHREDTDYFSQPRALFNLLSEEEHQRMFTRIAGELSQVPEAIQRRQIALFTQVDPAYGAGVKKALGLN
>Mature_480_residues
MMSKKKGLTTAAGAPVVDNNNVITAGRRGPMLLQDVWFLEKLAHFDREVIPERRMHAKGSGAYGTFTVTHDITQYTRAKI
FSEIGKKTDMFVRFSTVAGERGAADAERDIRGFAMKFYTEEGNWDLVGNDTPVFYLRDPLKFPDLNHVVKRDPRTNLRNP
VYKWDFFSQLPEALHQLTIDFSDRGLPKSYRHMHGFGSHTFSLINANNERFWVKFHFRCQQGIENLMDDEAEKLIGSDRE
SSQRDLYEAIERGDFPRWKLQIQVMPEHEASQTPYNPFDLTKVWPHGDYPLIDVGYFELNRNPENYFAEVEQSSFNPANV
VPGISFSPDRMLQGRLFSYGDAARYRLGVNHHQIPVNSAKCPFHNYHRDGAMRVDGNSGNGATYEPNSFGLFQEQPDFSE
PPLTLEGAADHWNHREDTDYFSQPRALFNLLSEEEHQRMFTRIAGELSQVPEAIQRRQIALFTQVDPAYGAGVKKALGLN

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=479, Percent_Identity=53.6534446764092, Blast_Score=518, Evalue=1e-147,
Organism=Escherichia coli, GI48994891, Length=494, Percent_Identity=42.3076923076923, Blast_Score=372, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI71998444, Length=479, Percent_Identity=52.1920668058455, Blast_Score=510, Evalue=1e-145,
Organism=Caenorhabditis elegans, GI25147792, Length=479, Percent_Identity=49.6868475991649, Blast_Score=486, Evalue=1e-137,
Organism=Caenorhabditis elegans, GI25151141, Length=475, Percent_Identity=49.8947368421053, Blast_Score=485, Evalue=1e-137,
Organism=Saccharomyces cerevisiae, GI6320462, Length=483, Percent_Identity=44.9275362318841, Blast_Score=397, Evalue=1e-111,
Organism=Saccharomyces cerevisiae, GI6321525, Length=507, Percent_Identity=34.7140039447732, Blast_Score=299, Evalue=8e-82,
Organism=Drosophila melanogaster, GI17981717, Length=482, Percent_Identity=50.4149377593361, Blast_Score=469, Evalue=1e-132,
Organism=Drosophila melanogaster, GI19920968, Length=480, Percent_Identity=46.0416666666667, Blast_Score=444, Evalue=1e-125,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 55024; Mature: 55024

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00438 CATALASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSKKKGLTTAAGAPVVDNNNVITAGRRGPMLLQDVWFLEKLAHFDREVIPERRMHAKGS
CCCCCCCCCCCCCCCEECCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCCC
GAYGTFTVTHDITQYTRAKIFSEIGKKTDMFVRFSTVAGERGAADAERDIRGFAMKFYTE
CCEEEEEEEHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCHHHHHHHEEEEEEEC
EGNWDLVGNDTPVFYLRDPLKFPDLNHVVKRDPRTNLRNPVYKWDFFSQLPEALHQLTID
CCCEEEECCCCCEEEEECCCCCCCCHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHEEEC
FSDRGLPKSYRHMHGFGSHTFSLINANNERFWVKFHFRCQQGIENLMDDEAEKLIGSDRE
CCCCCCCHHHHHHCCCCCCEEEEEECCCCEEEEEEEEEHHHHHHHHHHHHHHHHHCCCCC
SSQRDLYEAIERGDFPRWKLQIQVMPEHEASQTPYNPFDLTKVWPHGDYPLIDVGYFELN
HHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCCEEECCCCCCCEEEEEEEEEC
RNPENYFAEVEQSSFNPANVVPGISFSPDRMLQGRLFSYGDAARYRLGVNHHQIPVNSAK
CCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCHHHCCCCCHHEEECCCCCCCCCCCCC
CPFHNYHRDGAMRVDGNSGNGATYEPNSFGLFQEQPDFSEPPLTLEGAADHWNHREDTDY
CCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCHHCCCCCCCCHH
FSQPRALFNLLSEEEHQRMFTRIAGELSQVPEAIQRRQIALFTQVDPAYGAGVKKALGLN
HHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCHHCCCHHHHHCCC
>Mature Secondary Structure
MMSKKKGLTTAAGAPVVDNNNVITAGRRGPMLLQDVWFLEKLAHFDREVIPERRMHAKGS
CCCCCCCCCCCCCCCEECCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCCC
GAYGTFTVTHDITQYTRAKIFSEIGKKTDMFVRFSTVAGERGAADAERDIRGFAMKFYTE
CCEEEEEEEHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCHHHHHHHEEEEEEEC
EGNWDLVGNDTPVFYLRDPLKFPDLNHVVKRDPRTNLRNPVYKWDFFSQLPEALHQLTID
CCCEEEECCCCCEEEEECCCCCCCCHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHEEEC
FSDRGLPKSYRHMHGFGSHTFSLINANNERFWVKFHFRCQQGIENLMDDEAEKLIGSDRE
CCCCCCCHHHHHHCCCCCCEEEEEECCCCEEEEEEEEEHHHHHHHHHHHHHHHHHCCCCC
SSQRDLYEAIERGDFPRWKLQIQVMPEHEASQTPYNPFDLTKVWPHGDYPLIDVGYFELN
HHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCCEEECCCCCCCEEEEEEEEEC
RNPENYFAEVEQSSFNPANVVPGISFSPDRMLQGRLFSYGDAARYRLGVNHHQIPVNSAK
CCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCHHHCCCCCHHEEECCCCCCCCCCCCC
CPFHNYHRDGAMRVDGNSGNGATYEPNSFGLFQEQPDFSEPPLTLEGAADHWNHREDTDY
CCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCHHCCCCCCCCHH
FSQPRALFNLLSEEEHQRMFTRIAGELSQVPEAIQRRQIALFTQVDPAYGAGVKKALGLN
HHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCHHCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7786407; 7791219; 8901874; 12486720 [H]