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The map label for this gene is metQ

Identifier: 218928240

GI number: 218928240

Start: 1213727

End: 1214542

Strand: Reverse

Name: metQ

Synonym: YPO1071

Alternate gene names: 218928240

Gene position: 1214542-1213727 (Counterclockwise)

Preceding gene: 218928241

Following gene: 218928239

Centisome position: 26.1

GC content: 44.61

Gene sequence:

>816_bases
ATGTCTTTAAAATTCAAATCTATCGCAGCAATTAGTGCGCTGATTGGTACCTTGACTTTGGTGGGTTGCGGCCCGACGGA
AAAAGCGCCAAACCATATTAAAGTTGGCGTTATTGTCGGTGCAGAGCAACAAGTTGCCGAAGTGGCTCAGAAAGTGGCTA
AAGAAAAGTACGGTCTGGACGTTGAACTGGTGACATTCAATGACTATGTGTTACCAAACGAAGCACTGAGCAAAGGGGAT
ATCGACCTTAACGCTTTCCAGCATAAACCTTATCTGGATCAGCAAATCAAAGACCGTGGCTACAAACTGGTTTCTGTTGG
CAACTCGTTCGTTTACCCCATTGCCGGCTATTCCAAGAAAATCAAGTCACTGGATGAACTACAACCTGGATCTCAGGTCG
CCCTACCAAATGACCCTACTAATTTGGGCCGTTCTCTGTTATTGCTACAAAGCGTTGGTCTGATTAAGCTGAAAGACGGT
GTTGGCCTGCTGCCAACCGTATTAGATGTGGTTGAGAACCCTAAAAATCTGAAACTGGTTGAGTTGGAAGCACCTCAATT
ACCACGTTCTTTGGATGACCAACAAATCGCTCTGGCGATTATCAATACCACTTACGCTAGCCAAATTGGCCTGACACCAG
CTAAAGATGGTCTGTTTGTGGAAGATAAAGAATCACCGTATGTGAATCTGATTGTTGCCCGCGAAGACAATAAAGATGCG
GAAAATGTGAAAAAATTTGTTCAGGCTTACCAGTCTGACGAAGTTTATGATGCAGCGAATAAAGCATTCAACGGTGGCGC
AGTAAAAGGCTGGTAA

Upstream 100 bases:

>100_bases
TGGTGATCGGATAGTCAAAGCCGTTACGCACAAATAGTGATTAATCAGCGACTGCCTCACACAGCGGCGCATCTTAACGA
ATGTCTATAGAGGAAGGGAT

Downstream 100 bases:

>100_bases
TCTTTAATTACCTCTTTTATTGAATATATCGACAAGACGGGCTATAGCCCGTCTTGTTATTTGAATAATAGATTGCTTCA
ATAGCACAACTTAAATGAAT

Product: DL-methionine transporter substrate-binding subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 271; Mature: 270

Protein sequence:

>271_residues
MSLKFKSIAAISALIGTLTLVGCGPTEKAPNHIKVGVIVGAEQQVAEVAQKVAKEKYGLDVELVTFNDYVLPNEALSKGD
IDLNAFQHKPYLDQQIKDRGYKLVSVGNSFVYPIAGYSKKIKSLDELQPGSQVALPNDPTNLGRSLLLLQSVGLIKLKDG
VGLLPTVLDVVENPKNLKLVELEAPQLPRSLDDQQIALAIINTTYASQIGLTPAKDGLFVEDKESPYVNLIVAREDNKDA
ENVKKFVQAYQSDEVYDAANKAFNGGAVKGW

Sequences:

>Translated_271_residues
MSLKFKSIAAISALIGTLTLVGCGPTEKAPNHIKVGVIVGAEQQVAEVAQKVAKEKYGLDVELVTFNDYVLPNEALSKGD
IDLNAFQHKPYLDQQIKDRGYKLVSVGNSFVYPIAGYSKKIKSLDELQPGSQVALPNDPTNLGRSLLLLQSVGLIKLKDG
VGLLPTVLDVVENPKNLKLVELEAPQLPRSLDDQQIALAIINTTYASQIGLTPAKDGLFVEDKESPYVNLIVAREDNKDA
ENVKKFVQAYQSDEVYDAANKAFNGGAVKGW
>Mature_270_residues
SLKFKSIAAISALIGTLTLVGCGPTEKAPNHIKVGVIVGAEQQVAEVAQKVAKEKYGLDVELVTFNDYVLPNEALSKGDI
DLNAFQHKPYLDQQIKDRGYKLVSVGNSFVYPIAGYSKKIKSLDELQPGSQVALPNDPTNLGRSLLLLQSVGLIKLKDGV
GLLPTVLDVVENPKNLKLVELEAPQLPRSLDDQQIALAIINTTYASQIGLTPAKDGLFVEDKESPYVNLIVAREDNKDAE
NVKKFVQAYQSDEVYDAANKAFNGGAVKGW

Specific function: This protein is a component of a D-methionine permease, a binding protein-dependent, ATP-driven transport system

COG id: COG1464

COG function: function code P; ABC-type metal ion transport system, periplasmic component/surface antigen

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nlpA lipoprotein family

Homologues:

Organism=Escherichia coli, GI1786396, Length=271, Percent_Identity=90.4059040590406, Blast_Score=499, Evalue=1e-143,
Organism=Escherichia coli, GI1790093, Length=249, Percent_Identity=62.2489959839357, Blast_Score=328, Evalue=2e-91,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): METQ_YERPE (Q8ZH40)

Other databases:

- EMBL:   AL590842
- EMBL:   AE009952
- EMBL:   AE017042
- PIR:   AG0131
- RefSeq:   NP_670405.1
- RefSeq:   NP_994085.1
- RefSeq:   YP_002346115.1
- ProteinModelPortal:   Q8ZH40
- SMR:   Q8ZH40
- IntAct:   Q8ZH40
- GeneID:   1148053
- GeneID:   1173912
- GeneID:   2763768
- GenomeReviews:   AE009952_GR
- GenomeReviews:   AE017042_GR
- GenomeReviews:   AL590842_GR
- KEGG:   ype:YPO1071
- KEGG:   ypk:y3106
- KEGG:   ypm:YP_2778
- HOGENOM:   HBG661773
- OMA:   TYASQIN
- ProtClustDB:   PRK11063
- BioCyc:   YPES187410:Y3106-MONOMER
- BioCyc:   YPES214092:YPO1071-MONOMER
- InterPro:   IPR004872
- InterPro:   IPR004478
- TIGRFAMs:   TIGR00363

Pfam domain/function: PF03180 Lipoprotein_9

EC number: NA

Molecular weight: Translated: 29377; Mature: 29246

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS51257 PROKAR_LIPOPROTEIN; PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLKFKSIAAISALIGTLTLVGCGPTEKAPNHIKVGVIVGAEQQVAEVAQKVAKEKYGLD
CCCCHHHHHHHHHHHHHHEEEECCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHCCC
VELVTFNDYVLPNEALSKGDIDLNAFQHKPYLDQQIKDRGYKLVSVGNSFVYPIAGYSKK
EEEEEECCEECCCHHHCCCCCCEEHCCCCCCHHHHHHHCCEEEEEECCCEEEECCCHHHH
IKSLDELQPGSQVALPNDPTNLGRSLLLLQSVGLIKLKDGVGLLPTVLDVVENPKNLKLV
HHHHHHCCCCCEEECCCCHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHCCCCCEEEE
ELEAPQLPRSLDDQQIALAIINTTYASQIGLTPAKDGLFVEDKESPYVNLIVAREDNKDA
EECCCCCCCCCCCCEEEEEEEEHHHHHHCCCCCCCCCEEEECCCCCEEEEEEEECCCCCH
ENVKKFVQAYQSDEVYDAANKAFNGGAVKGW
HHHHHHHHHHCCCCHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SLKFKSIAAISALIGTLTLVGCGPTEKAPNHIKVGVIVGAEQQVAEVAQKVAKEKYGLD
CCCHHHHHHHHHHHHHHEEEECCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHCCC
VELVTFNDYVLPNEALSKGDIDLNAFQHKPYLDQQIKDRGYKLVSVGNSFVYPIAGYSKK
EEEEEECCEECCCHHHCCCCCCEEHCCCCCCHHHHHHHCCEEEEEECCCEEEECCCHHHH
IKSLDELQPGSQVALPNDPTNLGRSLLLLQSVGLIKLKDGVGLLPTVLDVVENPKNLKLV
HHHHHHCCCCCEEECCCCHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHCCCCCEEEE
ELEAPQLPRSLDDQQIALAIINTTYASQIGLTPAKDGLFVEDKESPYVNLIVAREDNKDA
EECCCCCCCCCCCCEEEEEEEEHHHHHHCCCCCCCCCEEEECCCCCEEEEEEEECCCCCH
ENVKKFVQAYQSDEVYDAANKAFNGGAVKGW
HHHHHHHHHHCCCCHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430