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The map label for this gene is accA [H]

Identifier: 218928228

GI number: 218928228

Start: 1204374

End: 1205333

Strand: Direct

Name: accA [H]

Synonym: YPO1060

Alternate gene names: 218928228

Gene position: 1204374-1205333 (Clockwise)

Preceding gene: 218928227

Following gene: 218928229

Centisome position: 25.88

GC content: 48.12

Gene sequence:

>960_bases
ATGAGTCTGAATTTTCTTGATTTTGAACAGCCGATTGCAGAGCTGGAAGCGAAAATTGACTCGCTGACTGCAGTCAGCCG
TCAAGACGAAAAATTAGATATTAATCTGGATGAAGAGGTCCAGCGTCTGCGTGAGAAAAGTGTTGAGCTGACGCGGAAAA
TTTTCTCGGACCTCGGCGCATGGCAGATTGCCCAATTGGCACGCCATCCTCGTCGTCCTTATACCCTGGATTATATCGCT
AATATCTTTACCGATTTCGAAGAGCTGGCTGGTGATCGTGCTTATGCCGATGATAAAGCTATTGTTGGCGGTATTGCACG
TCTGGATGGGCGCCCGGTGATGATTATTGGTCATCAAAAAGGGCGTGAAACCAAAGAGAAGATCCGTCGTAACTTTGGTA
TGCCAGCACCAGAAGGGTATCGTAAAGCTTTACGTCTGATGGAAATGGCTGAACGCTTTAAGTTACCCATTATTACTTTC
ATCGATACACCGGGGGCTTATCCGGGTGTTGGGGCGGAAGAACGTGGTCAATCAGAAGCGATTGCGCGCAACTTGCGTGA
AATGTCACGACTGAATGTCCCTATCGTCTGTACCGTGATTGGTGAAGGTGGATCTGGTGGTGCGTTGGCTATCGGTGTGG
GTGATAAAGTGAATATGCTGCAATACAGCACTTATTCTGTTATCTCTCCAGAAGGTTGCGCCTCTATTCTGTGGAAAAGT
GCGGATAAAGCGCCATTAGCCGCAGAAGCGATGGGCATTACTGCACATCGCCTAAAAGAACTGAAGATGATTGACTCAGT
GATCCCCGAGCCGTTGGGGGGCGCACATCGCGATTACGCCGCGATTGCTATCTCACTGAAAGCGCAACTGTTGGCAGATC
TCAATGATTTGGATGTGCTGAATGACGAAGAGTTATTGAATCGTCGTTATCAGCGCTTGATGAACTACGGCTATTGCTGA

Upstream 100 bases:

>100_bases
CACATGGCGCGTGACGCCCACCGATCGCTTATTAATCGATTTGCGAACGTTGGTAGGTAATGAGCAAGTGGAACTGGAAT
TTGACTAAAATAGGAATGCT

Downstream 100 bases:

>100_bases
GTTGATTGCCAACTGATAAAAGCCGGTGCGGAATTTAAGCGCCGGTTTTTTTTATCTATTTTTTACTGAAGACCCGAATT
TAGTTAAGCAATCTATACCC

Product: acetyl-CoA carboxylase carboxyltransferase subunit alpha

Products: NA

Alternate protein names: ACCase subunit alpha; Acetyl-CoA carboxylase carboxyltransferase subunit alpha [H]

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MSLNFLDFEQPIAELEAKIDSLTAVSRQDEKLDINLDEEVQRLREKSVELTRKIFSDLGAWQIAQLARHPRRPYTLDYIA
NIFTDFEELAGDRAYADDKAIVGGIARLDGRPVMIIGHQKGRETKEKIRRNFGMPAPEGYRKALRLMEMAERFKLPIITF
IDTPGAYPGVGAEERGQSEAIARNLREMSRLNVPIVCTVIGEGGSGGALAIGVGDKVNMLQYSTYSVISPEGCASILWKS
ADKAPLAAEAMGITAHRLKELKMIDSVIPEPLGGAHRDYAAIAISLKAQLLADLNDLDVLNDEELLNRRYQRLMNYGYC

Sequences:

>Translated_319_residues
MSLNFLDFEQPIAELEAKIDSLTAVSRQDEKLDINLDEEVQRLREKSVELTRKIFSDLGAWQIAQLARHPRRPYTLDYIA
NIFTDFEELAGDRAYADDKAIVGGIARLDGRPVMIIGHQKGRETKEKIRRNFGMPAPEGYRKALRLMEMAERFKLPIITF
IDTPGAYPGVGAEERGQSEAIARNLREMSRLNVPIVCTVIGEGGSGGALAIGVGDKVNMLQYSTYSVISPEGCASILWKS
ADKAPLAAEAMGITAHRLKELKMIDSVIPEPLGGAHRDYAAIAISLKAQLLADLNDLDVLNDEELLNRRYQRLMNYGYC
>Mature_318_residues
SLNFLDFEQPIAELEAKIDSLTAVSRQDEKLDINLDEEVQRLREKSVELTRKIFSDLGAWQIAQLARHPRRPYTLDYIAN
IFTDFEELAGDRAYADDKAIVGGIARLDGRPVMIIGHQKGRETKEKIRRNFGMPAPEGYRKALRLMEMAERFKLPIITFI
DTPGAYPGVGAEERGQSEAIARNLREMSRLNVPIVCTVIGEGGSGGALAIGVGDKVNMLQYSTYSVISPEGCASILWKSA
DKAPLAAEAMGITAHRLKELKMIDSVIPEPLGGAHRDYAAIAISLKAQLLADLNDLDVLNDEELLNRRYQRLMNYGYC

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-Co

COG id: COG0825

COG function: function code I; Acetyl-CoA carboxylase alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccA family [H]

Homologues:

Organism=Escherichia coli, GI1786382, Length=319, Percent_Identity=90.282131661442, Blast_Score=590, Evalue=1e-170,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001095
- InterPro:   IPR011763 [H]

Pfam domain/function: PF03255 ACCA [H]

EC number: =6.4.1.2 [H]

Molecular weight: Translated: 35496; Mature: 35365

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLNFLDFEQPIAELEAKIDSLTAVSRQDEKLDINLDEEVQRLREKSVELTRKIFSDLGA
CCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHCCH
WQIAQLARHPRRPYTLDYIANIFTDFEELAGDRAYADDKAIVGGIARLDGRPVMIIGHQK
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEEECCC
GRETKEKIRRNFGMPAPEGYRKALRLMEMAERFKLPIITFIDTPGAYPGVGAEERGQSEA
CCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHCCHHHH
IARNLREMSRLNVPIVCTVIGEGGSGGALAIGVGDKVNMLQYSTYSVISPEGCASILWKS
HHHHHHHHHHCCCCEEEEEEECCCCCCEEEEECCCCCCEEEECCCCEECCHHHHHHHHHC
ADKAPLAAEAMGITAHRLKELKMIDSVIPEPLGGAHRDYAAIAISLKAQLLADLNDLDVL
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
NDEELLNRRYQRLMNYGYC
CHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SLNFLDFEQPIAELEAKIDSLTAVSRQDEKLDINLDEEVQRLREKSVELTRKIFSDLGA
CCCCCCHHHHHHHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHCCH
WQIAQLARHPRRPYTLDYIANIFTDFEELAGDRAYADDKAIVGGIARLDGRPVMIIGHQK
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCEEEEEECCC
GRETKEKIRRNFGMPAPEGYRKALRLMEMAERFKLPIITFIDTPGAYPGVGAEERGQSEA
CCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHCCHHHH
IARNLREMSRLNVPIVCTVIGEGGSGGALAIGVGDKVNMLQYSTYSVISPEGCASILWKS
HHHHHHHHHHCCCCEEEEEEECCCCCCEEEEECCCCCCEEEECCCCEECCHHHHHHHHHC
ADKAPLAAEAMGITAHRLKELKMIDSVIPEPLGGAHRDYAAIAISLKAQLLADLNDLDVL
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCC
NDEELLNRRYQRLMNYGYC
CHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]