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The map label for this gene is rlmM [H]

Identifier: 218928199

GI number: 218928199

Start: 1171394

End: 1172500

Strand: Direct

Name: rlmM [H]

Synonym: YPO1031

Alternate gene names: 218928199

Gene position: 1171394-1172500 (Clockwise)

Preceding gene: 218928198

Following gene: 218928203

Centisome position: 25.17

GC content: 45.98

Gene sequence:

>1107_bases
ATGAATAATAAAATTGCTTTATATTGCCGCTCCGGCTTTGAGAAAGAGTGTGCGGCAGAAATAACAGAGAAGGCTGCACA
GCTCGAAATCTTTGGTTTTGCACGGGTAAAAGAAAACAGTGGCTATGTATTGTTTGAATGCTACCAGTTAGAGGATGCGG
ATCGACTCATCCGTGAAATACCGTTCCGCGAGTTTATTTTCGCCCGCCAAATGATGGTGGTGGGGGAGTTATTGAAAGAC
TTACCCCCAGAAGACCGTGTGTCACCGATCGTGGGAATGTTGGTTGGCGTTATTGAAAAAGCTGGCGAGTTACGTGTTGA
GGTGGCCGACACCAATGAAAGCAAAGAGTTACTCAAATTTTGCCGTAAGCTGACGGTACCTTTGCGTAGTGCTTTGCGTG
AACAGAAAATTCTGTCCGCTCGTGAGAATGCACATCGGCCAGTGGTGCATGTGTTCTTTATTGCGCCGGGTTGTTGTTAT
GTTGGTTATTCTTACAGCAATAATAACTCTCCATTCTATATGGGGATCCCTCGACTTAAATTCCCCTCCGATGCACCAAG
TCGCTCAACCTTAAAACTGGAAGAGGCATTCCATGTATTTATCCCCGCGGATGAATGGGAGGAGCGTTTAGCCAGTGGTA
TGCATGCTGTCGATTTAGGCGCTTGTCCCGGTGGCTGGACTTATCAATTAGTTCAACGCAGCATGATGATACAAGCGGTT
GATAATGGTTTGATGGCACAAAGCCTGATGGATACGGGGCAGGTCACACATCACCGTGCTGATGGTTTTAAGTATGAGCC
TACACGCAGCAATATTTATTGGTTAGTGTGTGACATGGTGGAAAAACCAACAAAAGTCACGCAGCTTATCACCAAATGGC
TAGTCAATGGTTGGTGCCGTGAAGCGATCTTCAACCTGAAATTACCAATGAAAAAGCGTTATGAAGAAGTTGTACAAAAT
TTAGCAATGATGGATGAGCAGTTGAAAGAAAACGGTATTAATGCTGATATCCATGCCAAACAGCTCTACCATGATCGCGA
AGAAGTTACGGTGCATGTCCGTCGTATCTGGTCGGGTGCACCGGGCCGCCGTGATGAGCGTTATTAG

Upstream 100 bases:

>100_bases
CTGTGGATATATATCACGCCAGTAGGCGGAGTCTGTTTTCTGGCGGGATGGATTTTGATGTTGATTGGCGCACTGCGTCT
AAGAAAAAGGGCAGAACGCC

Downstream 100 bases:

>100_bases
GTTTTAGCGATAGCGTAACATCATATTTAAGGGGCCTGTTGGCCCCTGAGGTTATTGACAAAGTGCCCGCGACGGAGAGA
ACAGGCAGATCGTAAAGACG

Product: putative RNA 2'-O-ribose methyltransferase

Products: NA

Alternate protein names: 23S rRNA 2'-O-ribose methyltransferase rlmM [H]

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MNNKIALYCRSGFEKECAAEITEKAAQLEIFGFARVKENSGYVLFECYQLEDADRLIREIPFREFIFARQMMVVGELLKD
LPPEDRVSPIVGMLVGVIEKAGELRVEVADTNESKELLKFCRKLTVPLRSALREQKILSARENAHRPVVHVFFIAPGCCY
VGYSYSNNNSPFYMGIPRLKFPSDAPSRSTLKLEEAFHVFIPADEWEERLASGMHAVDLGACPGGWTYQLVQRSMMIQAV
DNGLMAQSLMDTGQVTHHRADGFKYEPTRSNIYWLVCDMVEKPTKVTQLITKWLVNGWCREAIFNLKLPMKKRYEEVVQN
LAMMDEQLKENGINADIHAKQLYHDREEVTVHVRRIWSGAPGRRDERY

Sequences:

>Translated_368_residues
MNNKIALYCRSGFEKECAAEITEKAAQLEIFGFARVKENSGYVLFECYQLEDADRLIREIPFREFIFARQMMVVGELLKD
LPPEDRVSPIVGMLVGVIEKAGELRVEVADTNESKELLKFCRKLTVPLRSALREQKILSARENAHRPVVHVFFIAPGCCY
VGYSYSNNNSPFYMGIPRLKFPSDAPSRSTLKLEEAFHVFIPADEWEERLASGMHAVDLGACPGGWTYQLVQRSMMIQAV
DNGLMAQSLMDTGQVTHHRADGFKYEPTRSNIYWLVCDMVEKPTKVTQLITKWLVNGWCREAIFNLKLPMKKRYEEVVQN
LAMMDEQLKENGINADIHAKQLYHDREEVTVHVRRIWSGAPGRRDERY
>Mature_368_residues
MNNKIALYCRSGFEKECAAEITEKAAQLEIFGFARVKENSGYVLFECYQLEDADRLIREIPFREFIFARQMMVVGELLKD
LPPEDRVSPIVGMLVGVIEKAGELRVEVADTNESKELLKFCRKLTVPLRSALREQKILSARENAHRPVVHVFFIAPGCCY
VGYSYSNNNSPFYMGIPRLKFPSDAPSRSTLKLEEAFHVFIPADEWEERLASGMHAVDLGACPGGWTYQLVQRSMMIQAV
DNGLMAQSLMDTGQVTHHRADGFKYEPTRSNIYWLVCDMVEKPTKVTQLITKWLVNGWCREAIFNLKLPMKKRYEEVVQN
LAMMDEQLKENGINADIHAKQLYHDREEVTVHVRRIWSGAPGRRDERY

Specific function: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA [H]

COG id: COG2933

COG function: function code R; Predicted SAM-dependent methyltransferase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RlmE family. RlmM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789171, Length=365, Percent_Identity=78.0821917808219, Blast_Score=610, Evalue=1e-176,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011224
- InterPro:   IPR002877 [H]

Pfam domain/function: PF01728 FtsJ [H]

EC number: NA

Molecular weight: Translated: 42307; Mature: 42307

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNKIALYCRSGFEKECAAEITEKAAQLEIFGFARVKENSGYVLFECYQLEDADRLIREI
CCCCEEEEECCCCCHHHHHHHHHHHHHEEEEEEEEEECCCCEEEEEEEECCCHHHHHHHC
PFREFIFARQMMVVGELLKDLPPEDRVSPIVGMLVGVIEKAGELRVEVADTNESKELLKF
CHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHH
CRKLTVPLRSALREQKILSARENAHRPVVHVFFIAPGCCYVGYSYSNNNSPFYMGIPRLK
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEEEECCCCCCEEECCCCCC
FPSDAPSRSTLKLEEAFHVFIPADEWEERLASGMHAVDLGACPGGWTYQLVQRSMMIQAV
CCCCCCCCCEEEEECCEEEEECCHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHH
DNGLMAQSLMDTGQVTHHRADGFKYEPTRSNIYWLVCDMVEKPTKVTQLITKWLVNGWCR
HCHHHHHHHHHCCHHHHCCCCCCEECCCCCCEEEEEEEHHCCCHHHHHHHHHHHHHHHHH
EAIFNLKLPMKKRYEEVVQNLAMMDEQLKENGINADIHAKQLYHDREEVTVHVRRIWSGA
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHCCHHHHHHHHHHHHCCC
PGRRDERY
CCCCCCCC
>Mature Secondary Structure
MNNKIALYCRSGFEKECAAEITEKAAQLEIFGFARVKENSGYVLFECYQLEDADRLIREI
CCCCEEEEECCCCCHHHHHHHHHHHHHEEEEEEEEEECCCCEEEEEEEECCCHHHHHHHC
PFREFIFARQMMVVGELLKDLPPEDRVSPIVGMLVGVIEKAGELRVEVADTNESKELLKF
CHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHH
CRKLTVPLRSALREQKILSARENAHRPVVHVFFIAPGCCYVGYSYSNNNSPFYMGIPRLK
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEEEECCCCCCEEECCCCCC
FPSDAPSRSTLKLEEAFHVFIPADEWEERLASGMHAVDLGACPGGWTYQLVQRSMMIQAV
CCCCCCCCCEEEEECCEEEEECCHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHH
DNGLMAQSLMDTGQVTHHRADGFKYEPTRSNIYWLVCDMVEKPTKVTQLITKWLVNGWCR
HCHHHHHHHHHCCHHHHCCCCCCEECCCCCCEEEEEEEHHCCCHHHHHHHHHHHHHHHHH
EAIFNLKLPMKKRYEEVVQNLAMMDEQLKENGINADIHAKQLYHDREEVTVHVRRIWSGA
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHCCHHHHHHHHHHHHCCC
PGRRDERY
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA