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The map label for this gene is omp38 [H]

Identifier: 218928146

GI number: 218928146

Start: 1080541

End: 1082277

Strand: Reverse

Name: omp38 [H]

Synonym: YPO0974

Alternate gene names: 218928146

Gene position: 1082277-1080541 (Counterclockwise)

Preceding gene: 218928147

Following gene: 218928145

Centisome position: 23.26

GC content: 62.64

Gene sequence:

>1737_bases
ATGAGTCGGTGGTGGCAACGTGGGTTGTGGCTCTGGGCGGGTTTGCTGGCGGTCATCTTGTGTCTGGCATTTCTGCCGCT
CTCCCCGTGGGGGCGCTGGCTGATGCTGGCATGGGTGGTGCTGATTTGCATGCTGGGCGGGTCGCGGGCAGGGCGGCAAG
CGGCCGGTGCATCCTCTGATCCGCTGTTCGCCGGGTTGGCAACTGAAAACGGTCTTCTGCCTGAAAACAGTCGCTTACCG
GTGGTGTTGGTATGTGGTGATGGTCTGGCGTCATGGTTTGGTCGCGAACGGTCACACCAGAGTGCACAGGGCTGCTGGCT
GCGGGTGGATGATATCAGCACCCTGCGGCAGTTTGCCCGACAACTGCTGTGGCAACGGCCGGAATGGGCCGCTCAGTTGG
CGGTGATGATGGTCGTGAACCCGCAGCAACGCCGCGATGAGCGCCTGCTGGCCGCCGATCTGCAAGAGCTGCGCTGGCAA
CTGATGCAACTGCGCCGCGATAGCCGCCATCCTGTTCCCTTGCTCCTGAGCAGCACGGTGGCCACCTCGGTTGCCCGTGA
TACGGTCTGGCTGTCACAGCAGCAGACACCGCCGCTGACACTCTGGTCAACCGTCTCGACGCCGGGCTCTCTGGCCGACT
GGCAGCGTGCGGAAAGCCGTGCCGTACAGGCTGAACGACTGAAACAGGCGGTGCTGTTCAGCAGCCAGCATGACTGGCTG
AACGCACAGGTGCTGCCGGTATTGCAGGCACCCAATGCGGATGTTGACCCCCTTGCCCCGCAACAGATTATTCAACAGCA
GGTTGCCAGTCTGGCCGATCCGGTGCCTGCCTCGCTGTGGCAGCACTGGCTGGCGGCGCATACCACGCTGACACAGGTGG
CGGGTTGGCATCCACCGCCGCCCGCCGCCCATGACGCCTTACCGCTGCCGGATTTTGTCTTTTCAGCGCTTCCTCTCGGC
AGCGGGGTGTCGTCACGCCGTCGGGTACTGCGCCATGGTGTCACCTTACTGACGTTGGCGGCGATGGTGGCGTTGTGCAG
CAGCGCCTGGCAGAACCGGCAACTGTTGCACCGGGTGGCCTTTGATATCCGTCAGTACCACAGCGTGGCGATGACGGATT
ATTCCCCGAAAGCGCAGGCGGTGGCGGTATTACACCGTGATGCGGGGCTGCTTGATGAAGGGTACCGCAACGGTGAACCG
CTGCGTCTGGGCCTGGGGTTATATCGGGGGGAGCGGCTGCGCCCGCCGCTGTTGGCGGCGATCAAAAGCTACATCCCGCC
GCCTCCTCCGCCTCCCGCGCCACCGGCGCCGAAAACCGTGCGTCTCGACAGCCTGTCACTGTTCGATGTGGGTAAATTCA
CGCTGAATGCGGGGTCCACCAAAATGCTGGTCACGGCGCTGATCGACATCAAAGCCAAACCCGGCTGGCTGATCGTGGTG
GCGGGTCACACCGACATCACCGGCGATGCGCAGGCCAACCACATTCTGTCGCTTAAACGCGCCGAAGCATTACGGGACTG
GATGCTGTCAACCAGCGACGTCTCGCCGACCTGCTTTGCGGTGCAAGGTTACGGGGCCACACGCCCTATCGCCGACAACG
ATACTCCCGACGGTCGGGCGCTCAACCGCCGGGTCGAAATCAGTCTGGTACCGCAGGCTGATGCCTGTCAGGGGCCGGAT
GTAAAAACAGCGTCACAGGATGAAAGTGACGTATCAACGCAAGAAATGGAGAAGTAA

Upstream 100 bases:

>100_bases
TACGGCTCGGGCTGGCTGCGCTGATGGTCGCGCTGTTGTGGTGGGGCCTTGATCACTGGCTGTCCGGTCTGTTAGCCACC
TTACTGCCGGAGCCGGTGTA

Downstream 100 bases:

>100_bases
ACCATGGCAATTCCAGTTTATCTGTGGCTGAAAGACGACGGCGGTGCGGACATCAAGGGTTCTGTTGATGTGCAAAGCCG
TGAAGGCAGCATTGAGATCG

Product: putative OmpA family membrane protein

Products: NA

Alternate protein names: Outer membrane protein ompA; Outer membrane protein ompAb [H]

Number of amino acids: Translated: 578; Mature: 577

Protein sequence:

>578_residues
MSRWWQRGLWLWAGLLAVILCLAFLPLSPWGRWLMLAWVVLICMLGGSRAGRQAAGASSDPLFAGLATENGLLPENSRLP
VVLVCGDGLASWFGRERSHQSAQGCWLRVDDISTLRQFARQLLWQRPEWAAQLAVMMVVNPQQRRDERLLAADLQELRWQ
LMQLRRDSRHPVPLLLSSTVATSVARDTVWLSQQQTPPLTLWSTVSTPGSLADWQRAESRAVQAERLKQAVLFSSQHDWL
NAQVLPVLQAPNADVDPLAPQQIIQQQVASLADPVPASLWQHWLAAHTTLTQVAGWHPPPPAAHDALPLPDFVFSALPLG
SGVSSRRRVLRHGVTLLTLAAMVALCSSAWQNRQLLHRVAFDIRQYHSVAMTDYSPKAQAVAVLHRDAGLLDEGYRNGEP
LRLGLGLYRGERLRPPLLAAIKSYIPPPPPPPAPPAPKTVRLDSLSLFDVGKFTLNAGSTKMLVTALIDIKAKPGWLIVV
AGHTDITGDAQANHILSLKRAEALRDWMLSTSDVSPTCFAVQGYGATRPIADNDTPDGRALNRRVEISLVPQADACQGPD
VKTASQDESDVSTQEMEK

Sequences:

>Translated_578_residues
MSRWWQRGLWLWAGLLAVILCLAFLPLSPWGRWLMLAWVVLICMLGGSRAGRQAAGASSDPLFAGLATENGLLPENSRLP
VVLVCGDGLASWFGRERSHQSAQGCWLRVDDISTLRQFARQLLWQRPEWAAQLAVMMVVNPQQRRDERLLAADLQELRWQ
LMQLRRDSRHPVPLLLSSTVATSVARDTVWLSQQQTPPLTLWSTVSTPGSLADWQRAESRAVQAERLKQAVLFSSQHDWL
NAQVLPVLQAPNADVDPLAPQQIIQQQVASLADPVPASLWQHWLAAHTTLTQVAGWHPPPPAAHDALPLPDFVFSALPLG
SGVSSRRRVLRHGVTLLTLAAMVALCSSAWQNRQLLHRVAFDIRQYHSVAMTDYSPKAQAVAVLHRDAGLLDEGYRNGEP
LRLGLGLYRGERLRPPLLAAIKSYIPPPPPPPAPPAPKTVRLDSLSLFDVGKFTLNAGSTKMLVTALIDIKAKPGWLIVV
AGHTDITGDAQANHILSLKRAEALRDWMLSTSDVSPTCFAVQGYGATRPIADNDTPDGRALNRRVEISLVPQADACQGPD
VKTASQDESDVSTQEMEK
>Mature_577_residues
SRWWQRGLWLWAGLLAVILCLAFLPLSPWGRWLMLAWVVLICMLGGSRAGRQAAGASSDPLFAGLATENGLLPENSRLPV
VLVCGDGLASWFGRERSHQSAQGCWLRVDDISTLRQFARQLLWQRPEWAAQLAVMMVVNPQQRRDERLLAADLQELRWQL
MQLRRDSRHPVPLLLSSTVATSVARDTVWLSQQQTPPLTLWSTVSTPGSLADWQRAESRAVQAERLKQAVLFSSQHDWLN
AQVLPVLQAPNADVDPLAPQQIIQQQVASLADPVPASLWQHWLAAHTTLTQVAGWHPPPPAAHDALPLPDFVFSALPLGS
GVSSRRRVLRHGVTLLTLAAMVALCSSAWQNRQLLHRVAFDIRQYHSVAMTDYSPKAQAVAVLHRDAGLLDEGYRNGEPL
RLGLGLYRGERLRPPLLAAIKSYIPPPPPPPAPPAPKTVRLDSLSLFDVGKFTLNAGSTKMLVTALIDIKAKPGWLIVVA
GHTDITGDAQANHILSLKRAEALRDWMLSTSDVSPTCFAVQGYGATRPIADNDTPDGRALNRRVEISLVPQADACQGPDV
KTASQDESDVSTQEMEK

Specific function: Porin. Induces apoptosis in human laryngeal epithelial HEp-2 cells through caspases-dependent and AIF-dependent pathways. Purified omp38 enters the cells and localizes to the mitochondria, which leads to a release of proapoptotic molecules such as cytochr

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 OmpA-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011250
- InterPro:   IPR006664
- InterPro:   IPR006665
- InterPro:   IPR008722 [H]

Pfam domain/function: PF00691 OmpA; PF05736 OprF [H]

EC number: NA

Molecular weight: Translated: 63590; Mature: 63459

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: PS51123 OMPA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRWWQRGLWLWAGLLAVILCLAFLPLSPWGRWLMLAWVVLICMLGGSRAGRQAAGASSD
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
PLFAGLATENGLLPENSRLPVVLVCGDGLASWFGRERSHQSAQGCWLRVDDISTLRQFAR
CEEEEECCCCCCCCCCCCCCEEEEECCHHHHHHCCHHCCCCCCCCEEEECCHHHHHHHHH
QLLWQRPEWAAQLAVMMVVNPQQRRDERLLAADLQELRWQLMQLRRDSRHPVPLLLSSTV
HHHCCCCHHHHHEEEHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHH
ATSVARDTVWLSQQQTPPLTLWSTVSTPGSLADWQRAESRAVQAERLKQAVLFSSQHDWL
HHHHHHHHHEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
NAQVLPVLQAPNADVDPLAPQQIIQQQVASLADPVPASLWQHWLAAHTTLTQVAGWHPPP
CCEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
PAAHDALPLPDFVFSALPLGSGVSSRRRVLRHGVTLLTLAAMVALCSSAWQNRQLLHRVA
CCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FDIRQYHSVAMTDYSPKAQAVAVLHRDAGLLDEGYRNGEPLRLGLGLYRGERLRPPLLAA
HHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHCCCCCCCCEEEECCHHCCCCCCCHHHHH
IKSYIPPPPPPPAPPAPKTVRLDSLSLFDVGKFTLNAGSTKMLVTALIDIKAKPGWLIVV
HHHHCCCCCCCCCCCCCCEEEECCCCEEECCCEEECCCCHHHHHHHHHHEECCCCEEEEE
AGHTDITGDAQANHILSLKRAEALRDWMLSTSDVSPTCFAVQGYGATRPIADNDTPDGRA
ECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCH
LNRRVEISLVPQADACQGPDVKTASQDESDVSTQEMEK
HCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHCC
>Mature Secondary Structure 
SRWWQRGLWLWAGLLAVILCLAFLPLSPWGRWLMLAWVVLICMLGGSRAGRQAAGASSD
CHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
PLFAGLATENGLLPENSRLPVVLVCGDGLASWFGRERSHQSAQGCWLRVDDISTLRQFAR
CEEEEECCCCCCCCCCCCCCEEEEECCHHHHHHCCHHCCCCCCCCEEEECCHHHHHHHHH
QLLWQRPEWAAQLAVMMVVNPQQRRDERLLAADLQELRWQLMQLRRDSRHPVPLLLSSTV
HHHCCCCHHHHHEEEHEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHH
ATSVARDTVWLSQQQTPPLTLWSTVSTPGSLADWQRAESRAVQAERLKQAVLFSSQHDWL
HHHHHHHHHEECCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
NAQVLPVLQAPNADVDPLAPQQIIQQQVASLADPVPASLWQHWLAAHTTLTQVAGWHPPP
CCEEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
PAAHDALPLPDFVFSALPLGSGVSSRRRVLRHGVTLLTLAAMVALCSSAWQNRQLLHRVA
CCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FDIRQYHSVAMTDYSPKAQAVAVLHRDAGLLDEGYRNGEPLRLGLGLYRGERLRPPLLAA
HHHHHHHHHHCCCCCCCHHHHHHHHHCCCCHHCCCCCCCCEEEECCHHCCCCCCCHHHHH
IKSYIPPPPPPPAPPAPKTVRLDSLSLFDVGKFTLNAGSTKMLVTALIDIKAKPGWLIVV
HHHHCCCCCCCCCCCCCCEEEECCCCEEECCCEEECCCCHHHHHHHHHHEECCCCEEEEE
AGHTDITGDAQANHILSLKRAEALRDWMLSTSDVSPTCFAVQGYGATRPIADNDTPDGRA
ECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCH
LNRRVEISLVPQADACQGPDVKTASQDESDVSTQEMEK
HCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA