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The map label for this gene is clpB3 [H]

Identifier: 218928144

GI number: 218928144

Start: 1076980

End: 1079628

Strand: Reverse

Name: clpB3 [H]

Synonym: YPO0971

Alternate gene names: 218928144

Gene position: 1079628-1076980 (Counterclockwise)

Preceding gene: 218928145

Following gene: 218928143

Centisome position: 23.2

GC content: 58.51

Gene sequence:

>2649_bases
ATGACAACGCATTCAGCACACTTATTACGCCGCTTAAATCCCTATTGCGCACAGGCACTGGCCGGTGCTGCCACCCTGTG
TCAGACCCGCGCCCATGCCGAGATCACTGTCGAACACTGGTTGTTAAAACTGCTGGAGCAGGGCGAAGGCGATATCACGG
TGATTGCCCGGCGTTATGAGTGGGACATGGACAGCTTGTGGCAAGGGTTACTGGCCTATCTGGATACTTTGCCGCGCACG
GTACAGGGTAAACCCCAACTGTCCGCCGCGTTGCAGCAACTGATCAAAAGTGCCTGGCTGGATGCCTCGTTGCAGGAAAA
TGCTGATGCGGTGCGCTCGGTTCATCTAATGGCAGCGCTGATAAATTCGCCATCATTATTGGCCGCCGATGCCGCCTGGC
CGTTGCTCAGCCTGAGCACTACCCAACTACACCGCTTGTTGCCGTTGCTGGACAGCCAATCCGACGAACGCCCTGAAATA
CAGCAGGCCGCAGCACTGGCAGACAGCCCGGTCAATCTGACCGATGAGGCCGCGACGGTTACCTCCGCCAGTGGTCAGCC
GCAACTGAATGACGCGCTGCAAGCGGCGCTGGATAAATTTACCCTCGATGTCACCGCCAAAGCCCGTGCCAACCAGATTG
ATCCGATTTTTGGCCGCGACAGCGAAATCCGCCAGATGATCGACATCCTGTCGCGCCGCCGTAAAAACAACCCGATTTTG
GTGGGTGAACCGGGTGTGGGGAAAACCGCCTTGGTTGAAGGGCTGGCACTGCGCATTGCCGAGGGCAACGTACCGGACAG
CCTGAAAACCGTCAGTGTGCGCACACTGGATTTGGGTCTGTTACAGGCCGGTGCCGGGGTCAAAGGCGAGTTCGAACAGC
GCCTGAAAAATGTTATCGAGGCGGTGCAACAATCCCCCAGCCCGGTGCTGCTGTTTATCGACGAAGCCCACACCATTATC
GGGGCCGGTAATCAGGCCGGTGGTGCCGATGCGGCCAACCTGCTGAAACCGGCACTGGCGCGTGGCGAACTGCGCACCAT
CGCCGCCACCACCTGGTCCGAATACAAACAGTATTTTGAACGCGATGCCGCACTGGAGCGCCGCTTCCAGATGGTCAAAG
TGGACGAGCCGGATGATGACACCGCCTGCCTGATGCTGCGTGGCCTGAAAGAACGTTACGCCACCCATCACGGCGTGCAT
ATTCTGGACGCCGCTATCACCGCAGCGGTTACCCTGTCGCGCCGCTTCCTGACCGGCCGCCAACTGCCGGACAAAGCGGT
GGATCTGCTCGATACCGCCGGTGCCCGGGTGCGCATGAGCATTGACACCTTGCCGACTGCGCTGATGGCGATTAACGCCG
AGCTGGCCGCACTGGCGATGGAGCAACAGGCCATCGAACAGGACCTGCTCCTGCTGCCGAATGTCAGTTCAACGCGCTTA
CCTGAGATTGAGCAACGCCGCGCCGCGCTGGCGGTTGGGCAGCACACACTCGAACAGCAATATAAAGAAGAAAAACGGCT
GACCACCCTGATTATCGAGGCGCGTCAGGATATCGCCAACGTGGCACATCTGGTCGCGTTGCAGGAGGAACTCGTTCAGA
TCCAAGGCAACGCGCCGCTGCTGTCGCTGGACGTTGATGTGCGCACTGTTGCGGCTGTGATCGCCGACTGGACCGGCGTG
CCGCTGAGCAGTCTGTTGAAAGACGAACAGACCGATTTGTTGCAACTGGAAAACCATCTCGCCACCCGCGTAGTCGGGCA
GGATACGGCGCTGGGTGCGCTGGCGCAACGGCTGCGGGCGGCGAAAACCGGGCTGACATCAGAGAATGGCCCGCTGGGGG
TGTTCCTGCTGGTCGGGCCGAGTGGGATCGGCAAAACCGAAACCGCGCTGGCACTGGCCGACAGCCTGTTCGGCGGCGAG
AAATCGCTGATCACCATCAACTTATCGGAGTATCAGGAAGCTCACACCGTCTCCCAGTTGAAAGGGTCGCCCCCAGGTTA
TGTTGGCTACGGTCAGGGTGGTGTATTAACCGAAGCGGTACGTAAACGGCCTTACAGCGTGGTGCTGCTGGATGAAGTGG
AAAAAGCCCATCGTGATGTGCTGAACCTGTTCTATCAGGTGTTTGACCGGGGGTTCATGCGCGACGGTGAAGGGCGCGAA
ATTGATTTTCGTAACACAGTGATCCTAATGACGGCCAATTTAGGCAGTGATCATCTGATGCAGTTACTGGATGAACAACC
GGAAGCGACGCACAGTGATTTACACGAGCTGCTGCGCCCGATCCTGCGCGATCATTTCCAGCCCGCGCTATTAGCCCGCT
TCCAGACCTTGATCTACCGCCCACTGAATGCCATCGCATTGCGCACCATCGTCGAGATGAAACTGGCACAGGTCGCTAAA
CGCCTGAACAAACATTACGGCCTGCACTGCACCATTGAGGAAAGCCTCTACGACACACTGGTCGCCGCCTGCCTGCTGCC
GGACACCGGCGCACGCAACATCGACAGCCTGCTCAATCAACAAATCTTACCGGTATTGAGCCAGCAGCTGTTAAGCCGCA
TGAGCGAGCAACAGCGCACCACCTCGCTGACGCTGGGCTGGGATGAAGCCGACGGCATTACCCTTGAATTTGAAGGAGGC
GAAAAATGA

Upstream 100 bases:

>100_bases
TGTGCGCTGTCCGTGTGCAAACTGACTGCGACAATAACGCCAACTGAAACCGGCTTACTTATCCGGTATCGCAAAGGTTT
CGCAAACAAGGAAGATCTTA

Downstream 100 bases:

>100_bases
ATACCACTCTCCCGACTCTTCGGTTTGACCATAGCCACCACAAACTGGTGGTCCGCGACAGCACCGCCGCCGTTGATGTG
CTGGGCTTTGAAGGCCACGA

Product: Clp ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 882; Mature: 881

Protein sequence:

>882_residues
MTTHSAHLLRRLNPYCAQALAGAATLCQTRAHAEITVEHWLLKLLEQGEGDITVIARRYEWDMDSLWQGLLAYLDTLPRT
VQGKPQLSAALQQLIKSAWLDASLQENADAVRSVHLMAALINSPSLLAADAAWPLLSLSTTQLHRLLPLLDSQSDERPEI
QQAAALADSPVNLTDEAATVTSASGQPQLNDALQAALDKFTLDVTAKARANQIDPIFGRDSEIRQMIDILSRRRKNNPIL
VGEPGVGKTALVEGLALRIAEGNVPDSLKTVSVRTLDLGLLQAGAGVKGEFEQRLKNVIEAVQQSPSPVLLFIDEAHTII
GAGNQAGGADAANLLKPALARGELRTIAATTWSEYKQYFERDAALERRFQMVKVDEPDDDTACLMLRGLKERYATHHGVH
ILDAAITAAVTLSRRFLTGRQLPDKAVDLLDTAGARVRMSIDTLPTALMAINAELAALAMEQQAIEQDLLLLPNVSSTRL
PEIEQRRAALAVGQHTLEQQYKEEKRLTTLIIEARQDIANVAHLVALQEELVQIQGNAPLLSLDVDVRTVAAVIADWTGV
PLSSLLKDEQTDLLQLENHLATRVVGQDTALGALAQRLRAAKTGLTSENGPLGVFLLVGPSGIGKTETALALADSLFGGE
KSLITINLSEYQEAHTVSQLKGSPPGYVGYGQGGVLTEAVRKRPYSVVLLDEVEKAHRDVLNLFYQVFDRGFMRDGEGRE
IDFRNTVILMTANLGSDHLMQLLDEQPEATHSDLHELLRPILRDHFQPALLARFQTLIYRPLNAIALRTIVEMKLAQVAK
RLNKHYGLHCTIEESLYDTLVAACLLPDTGARNIDSLLNQQILPVLSQQLLSRMSEQQRTTSLTLGWDEADGITLEFEGG
EK

Sequences:

>Translated_882_residues
MTTHSAHLLRRLNPYCAQALAGAATLCQTRAHAEITVEHWLLKLLEQGEGDITVIARRYEWDMDSLWQGLLAYLDTLPRT
VQGKPQLSAALQQLIKSAWLDASLQENADAVRSVHLMAALINSPSLLAADAAWPLLSLSTTQLHRLLPLLDSQSDERPEI
QQAAALADSPVNLTDEAATVTSASGQPQLNDALQAALDKFTLDVTAKARANQIDPIFGRDSEIRQMIDILSRRRKNNPIL
VGEPGVGKTALVEGLALRIAEGNVPDSLKTVSVRTLDLGLLQAGAGVKGEFEQRLKNVIEAVQQSPSPVLLFIDEAHTII
GAGNQAGGADAANLLKPALARGELRTIAATTWSEYKQYFERDAALERRFQMVKVDEPDDDTACLMLRGLKERYATHHGVH
ILDAAITAAVTLSRRFLTGRQLPDKAVDLLDTAGARVRMSIDTLPTALMAINAELAALAMEQQAIEQDLLLLPNVSSTRL
PEIEQRRAALAVGQHTLEQQYKEEKRLTTLIIEARQDIANVAHLVALQEELVQIQGNAPLLSLDVDVRTVAAVIADWTGV
PLSSLLKDEQTDLLQLENHLATRVVGQDTALGALAQRLRAAKTGLTSENGPLGVFLLVGPSGIGKTETALALADSLFGGE
KSLITINLSEYQEAHTVSQLKGSPPGYVGYGQGGVLTEAVRKRPYSVVLLDEVEKAHRDVLNLFYQVFDRGFMRDGEGRE
IDFRNTVILMTANLGSDHLMQLLDEQPEATHSDLHELLRPILRDHFQPALLARFQTLIYRPLNAIALRTIVEMKLAQVAK
RLNKHYGLHCTIEESLYDTLVAACLLPDTGARNIDSLLNQQILPVLSQQLLSRMSEQQRTTSLTLGWDEADGITLEFEGG
EK
>Mature_881_residues
TTHSAHLLRRLNPYCAQALAGAATLCQTRAHAEITVEHWLLKLLEQGEGDITVIARRYEWDMDSLWQGLLAYLDTLPRTV
QGKPQLSAALQQLIKSAWLDASLQENADAVRSVHLMAALINSPSLLAADAAWPLLSLSTTQLHRLLPLLDSQSDERPEIQ
QAAALADSPVNLTDEAATVTSASGQPQLNDALQAALDKFTLDVTAKARANQIDPIFGRDSEIRQMIDILSRRRKNNPILV
GEPGVGKTALVEGLALRIAEGNVPDSLKTVSVRTLDLGLLQAGAGVKGEFEQRLKNVIEAVQQSPSPVLLFIDEAHTIIG
AGNQAGGADAANLLKPALARGELRTIAATTWSEYKQYFERDAALERRFQMVKVDEPDDDTACLMLRGLKERYATHHGVHI
LDAAITAAVTLSRRFLTGRQLPDKAVDLLDTAGARVRMSIDTLPTALMAINAELAALAMEQQAIEQDLLLLPNVSSTRLP
EIEQRRAALAVGQHTLEQQYKEEKRLTTLIIEARQDIANVAHLVALQEELVQIQGNAPLLSLDVDVRTVAAVIADWTGVP
LSSLLKDEQTDLLQLENHLATRVVGQDTALGALAQRLRAAKTGLTSENGPLGVFLLVGPSGIGKTETALALADSLFGGEK
SLITINLSEYQEAHTVSQLKGSPPGYVGYGQGGVLTEAVRKRPYSVVLLDEVEKAHRDVLNLFYQVFDRGFMRDGEGREI
DFRNTVILMTANLGSDHLMQLLDEQPEATHSDLHELLRPILRDHFQPALLARFQTLIYRPLNAIALRTIVEMKLAQVAKR
LNKHYGLHCTIEESLYDTLVAACLLPDTGARNIDSLLNQQILPVLSQQLLSRMSEQQRTTSLTLGWDEADGITLEFEGGE
K

Specific function: Required for secretion of hcp1 probably by providing the energy source for its translocation [H]

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=299, Percent_Identity=33.7792642140468, Blast_Score=162, Evalue=1e-39,
Organism=Escherichia coli, GI1788943, Length=690, Percent_Identity=43.4782608695652, Blast_Score=557, Evalue=1e-160,
Organism=Escherichia coli, GI1787109, Length=270, Percent_Identity=44.8148148148148, Blast_Score=243, Evalue=5e-65,
Organism=Saccharomyces cerevisiae, GI6320464, Length=696, Percent_Identity=41.5229885057471, Blast_Score=469, Evalue=1e-133,
Organism=Saccharomyces cerevisiae, GI6323002, Length=707, Percent_Identity=37.4823196605375, Blast_Score=445, Evalue=1e-125,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR017729
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 96521; Mature: 96389

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS00870 CLPAB_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTHSAHLLRRLNPYCAQALAGAATLCQTRAHAEITVEHWLLKLLEQGEGDITVIARRYE
CCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHCCCCCEEEEEEECC
WDMDSLWQGLLAYLDTLPRTVQGKPQLSAALQQLIKSAWLDASLQENADAVRSVHLMAAL
CCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
INSPSLLAADAAWPLLSLSTTQLHRLLPLLDSQSDERPEIQQAAALADSPVNLTDEAATV
HCCCCEEECCCCCCHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCHHEE
TSASGQPQLNDALQAALDKFTLDVTAKARANQIDPIFGRDSEIRQMIDILSRRRKNNPIL
ECCCCCCCHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEE
VGEPGVGKTALVEGLALRIAEGNVPDSLKTVSVRTLDLGLLQAGAGVKGEFEQRLKNVIE
EECCCCCHHHHHHHHHHEEECCCCCCCHHEEEEEEEHHHHHHCCCCCCHHHHHHHHHHHH
AVQQSPSPVLLFIDEAHTIIGAGNQAGGADAANLLKPALARGELRTIAATTWSEYKQYFE
HHHCCCCCEEEEEECCCEEEECCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
RDAALERRFQMVKVDEPDDDTACLMLRGLKERYATHHGVHILDAAITAAVTLSRRFLTGR
HHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCC
QLPDKAVDLLDTAGARVRMSIDTLPTALMAINAELAALAMEQQAIEQDLLLLPNVSSTRL
CCCHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCC
PEIEQRRAALAVGQHTLEQQYKEEKRLTTLIIEARQDIANVAHLVALQEELVQIQGNAPL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
LSLDVDVRTVAAVIADWTGVPLSSLLKDEQTDLLQLENHLATRVVGQDTALGALAQRLRA
EEECCHHHHHHHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
AKTGLTSENGPLGVFLLVGPSGIGKTETALALADSLFGGEKSLITINLSEYQEAHTVSQL
HHCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHH
KGSPPGYVGYGQGGVLTEAVRKRPYSVVLLDEVEKAHRDVLNLFYQVFDRGFMRDGEGRE
CCCCCCEECCCCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCE
IDFRNTVILMTANLGSDHLMQLLDEQPEATHSDLHELLRPILRDHFQPALLARFQTLIYR
EECCCEEEEEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
PLNAIALRTIVEMKLAQVAKRLNKHYGLHCTIEESLYDTLVAACLLPDTGARNIDSLLNQ
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHCCCCCCCHHHHHHHH
QILPVLSQQLLSRMSEQQRTTSLTLGWDEADGITLEFEGGEK
HHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCEEEEECCCCC
>Mature Secondary Structure 
TTHSAHLLRRLNPYCAQALAGAATLCQTRAHAEITVEHWLLKLLEQGEGDITVIARRYE
CCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHCCCCCEEEEEEECC
WDMDSLWQGLLAYLDTLPRTVQGKPQLSAALQQLIKSAWLDASLQENADAVRSVHLMAAL
CCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
INSPSLLAADAAWPLLSLSTTQLHRLLPLLDSQSDERPEIQQAAALADSPVNLTDEAATV
HCCCCEEECCCCCCHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCCCHHEE
TSASGQPQLNDALQAALDKFTLDVTAKARANQIDPIFGRDSEIRQMIDILSRRRKNNPIL
ECCCCCCCHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEE
VGEPGVGKTALVEGLALRIAEGNVPDSLKTVSVRTLDLGLLQAGAGVKGEFEQRLKNVIE
EECCCCCHHHHHHHHHHEEECCCCCCCHHEEEEEEEHHHHHHCCCCCCHHHHHHHHHHHH
AVQQSPSPVLLFIDEAHTIIGAGNQAGGADAANLLKPALARGELRTIAATTWSEYKQYFE
HHHCCCCCEEEEEECCCEEEECCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
RDAALERRFQMVKVDEPDDDTACLMLRGLKERYATHHGVHILDAAITAAVTLSRRFLTGR
HHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCC
QLPDKAVDLLDTAGARVRMSIDTLPTALMAINAELAALAMEQQAIEQDLLLLPNVSSTRL
CCCHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCC
PEIEQRRAALAVGQHTLEQQYKEEKRLTTLIIEARQDIANVAHLVALQEELVQIQGNAPL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCE
LSLDVDVRTVAAVIADWTGVPLSSLLKDEQTDLLQLENHLATRVVGQDTALGALAQRLRA
EEECCHHHHHHHHHHCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
AKTGLTSENGPLGVFLLVGPSGIGKTETALALADSLFGGEKSLITINLSEYQEAHTVSQL
HHCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHH
KGSPPGYVGYGQGGVLTEAVRKRPYSVVLLDEVEKAHRDVLNLFYQVFDRGFMRDGEGRE
CCCCCCEECCCCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCE
IDFRNTVILMTANLGSDHLMQLLDEQPEATHSDLHELLRPILRDHFQPALLARFQTLIYR
EECCCEEEEEEECCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
PLNAIALRTIVEMKLAQVAKRLNKHYGLHCTIEESLYDTLVAACLLPDTGARNIDSLLNQ
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHCCCCCCCHHHHHHHH
QILPVLSQQLLSRMSEQQRTTSLTLGWDEADGITLEFEGGEK
HHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]