Click here to switch to the map view.

The map label for this gene is manX [H]

Identifier: 218928010

GI number: 218928010

Start: 914680

End: 915177

Strand: Direct

Name: manX [H]

Synonym: YPO0834

Alternate gene names: 218928010

Gene position: 914680-915177 (Clockwise)

Preceding gene: 218928009

Following gene: 218928011

Centisome position: 19.65

GC content: 50.8

Gene sequence:

>498_bases
ATGACTCGGCCAAATATCGTCTGGACTCGTATTGATGAGCGTTTACTTCATGGACAGATCCGCATTACCTGGGGAAAGCA
CACCGAAGCCAATTTAATTCTGGTGGCCAATGATGACGCTGCCGATGGCCCAAACTCGGCTTTCATGCAGGCGGGAATGA
AAGCCTCCGCTGGCGGTGAATATGCAGTGCGCTTTTTCAGTATCCAGAAAACAATTGATGTCATCCATAAAGCCTCTCCT
CAGCAGAAGGTTTTCATTCTGTGTAACTCCCCGACGGATGTTGCGCGTTTGGTCGAAGGCGGTGTGCCAATTACTCAGTG
CAACGTGGGCAATATGCACTACCACGACGGTAAACGTCAGATTGCCAAAACAGTCTCTGTGGATGAAAAAGATCTGGATG
CTTTCCAACGTATGGCCGCGCTTGGCGTGGCCTGTACGGTGCAGAACACACCAGACCAAACGCCAATCAATGTGATTGAG
CTGGCCGCCAGGGCATAA

Upstream 100 bases:

>100_bases
ACAACACGCCGGATAGCCCATCTCCAACGGGTGAAATCAATCGCGTGGTGCAAGGTGTGACTATTTATCCATTTAAAAAA
TAACACACAGGAATATCCCT

Downstream 100 bases:

>100_bases
ATCGACGACTTATTACGCCAAGACATAGGGAATTAAAGGATAAATTATGCTTTTTGAAGCTACGTTAGTCGGAATCTGGG
CCTTCTTGTGCGGTATCGAC

Product: putative PTS transport protein

Products: NA

Alternate protein names: EIIB-Aga'; PTS system N-acetylgalactosamine-specific EIIB component 2 [H]

Number of amino acids: Translated: 165; Mature: 164

Protein sequence:

>165_residues
MTRPNIVWTRIDERLLHGQIRITWGKHTEANLILVANDDAADGPNSAFMQAGMKASAGGEYAVRFFSIQKTIDVIHKASP
QQKVFILCNSPTDVARLVEGGVPITQCNVGNMHYHDGKRQIAKTVSVDEKDLDAFQRMAALGVACTVQNTPDQTPINVIE
LAARA

Sequences:

>Translated_165_residues
MTRPNIVWTRIDERLLHGQIRITWGKHTEANLILVANDDAADGPNSAFMQAGMKASAGGEYAVRFFSIQKTIDVIHKASP
QQKVFILCNSPTDVARLVEGGVPITQCNVGNMHYHDGKRQIAKTVSVDEKDLDAFQRMAALGVACTVQNTPDQTPINVIE
LAARA
>Mature_164_residues
TRPNIVWTRIDERLLHGQIRITWGKHTEANLILVANDDAADGPNSAFMQAGMKASAGGEYAVRFFSIQKTIDVIHKASPQ
QKVFILCNSPTDVARLVEGGVPITQCNVGNMHYHDGKRQIAKTVSVDEKDLDAFQRMAALGVACTVQNTPDQTPINVIEL
AARA

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG3444

COG function: function code G; Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIB type-4 domain [H]

Homologues:

Organism=Escherichia coli, GI87082217, Length=158, Percent_Identity=48.1012658227848, Blast_Score=158, Evalue=2e-40,
Organism=Escherichia coli, GI1789527, Length=151, Percent_Identity=44.3708609271523, Blast_Score=131, Evalue=3e-32,
Organism=Escherichia coli, GI1788120, Length=157, Percent_Identity=36.3057324840764, Blast_Score=99, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004720
- InterPro:   IPR018455 [H]

Pfam domain/function: PF03830 PTSIIB_sorb [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 18054; Mature: 17923

Theoretical pI: Translated: 7.56; Mature: 7.56

Prosite motif: PS51101 PTS_EIIB_TYPE_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRPNIVWTRIDERLLHGQIRITWGKHTEANLILVANDDAADGPNSAFMQAGMKASAGGE
CCCCCEEEEEHHHHHHCCEEEEEECCCCCCEEEEEECCCCCCCCCHHHHHCCCCCCCCCC
YAVRFFSIQKTIDVIHKASPQQKVFILCNSPTDVARLVEGGVPITQCNVGNMHYHDGKRQ
EEEEEEHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHCCCCEEEECCCCEEEECCHHH
IAKTVSVDEKDLDAFQRMAALGVACTVQNTPDQTPINVIELAARA
HHHHCCCCHHHHHHHHHHHHHCEEEEECCCCCCCCHHHHEEEECC
>Mature Secondary Structure 
TRPNIVWTRIDERLLHGQIRITWGKHTEANLILVANDDAADGPNSAFMQAGMKASAGGE
CCCCEEEEEHHHHHHCCEEEEEECCCCCCEEEEEECCCCCCCCCHHHHHCCCCCCCCCC
YAVRFFSIQKTIDVIHKASPQQKVFILCNSPTDVARLVEGGVPITQCNVGNMHYHDGKRQ
EEEEEEHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHHCCCCEEEECCCCEEEECCHHH
IAKTVSVDEKDLDAFQRMAALGVACTVQNTPDQTPINVIELAARA
HHHHCCCCHHHHHHHHHHHHHCEEEEECCCCCCCCHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503; 8932697 [H]