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The map label for this gene is mdtO [H]

Identifier: 218927812

GI number: 218927812

Start: 679933

End: 681702

Strand: Reverse

Name: mdtO [H]

Synonym: YPO0618

Alternate gene names: 218927812

Gene position: 681702-679933 (Counterclockwise)

Preceding gene: 218927813

Following gene: 218927811

Centisome position: 14.65

GC content: 52.71

Gene sequence:

>1770_bases
ATGATATACGGCATCCCTGAATCTGCGATTAGTTGCTATCTCATTATTTTTGTTATGAAGCCGGATGGTGTAGAGAGCAT
GGTGATGGCCGTGGCGATAACGATCCTGGTGTCGTTGGTCGTCGGGTTGGTATTTCTGCTTATCCATTTCACCCTAGAGG
CCGCACCACTGCGCATGGCGGCCTTGATTGTCAGCTCGTTTCTCTTTCTCTATCTCGGATCGGCCAGTAAGCTCGGCCCG
GTAGGGAGTATTATTGCGTTGGTTATCGCTTATGTGATGACGTTACTGAGCAATATCCCAATGGGAGAAGTGGCCACGCG
GGGGCTGTTGTATGCCTGGTTGATGGCTGTTTCACCGATGTTGCTGATTATTGGGTTTAACCTTTTCTTTGGCCGAGCAC
CACAGACGTTATTGCGGGCCAGCTTAGCGGAGCGGTTATCCACGGTCGCCGAGACATTACGGTACCCCAATGCCGCCAAT
ATGGCGCGGGTTGGAGAACAGCTACAGGAAGGGCAACATGAGCATCAACAGCGGGCGCTTTTTGTTCGTATCTTTCATCT
ACGGCCCTCGGCTGAAGCGGCCTGGCTTGAAAGTGCCGTAAAAAGCAGTTACCGGCTACTCTTGGTAACCTCGGCGTTAC
CTCCTACCTCACCAGAGGCCGTGCGCCTTGAGCTTGCGGCCTACTGTAGTGATGCGGCTCAGGCGATTGCCAGCGGTGAT
CTCGCGGCCCCCCCTCACTTCGCGATTGAGGATACCAGCGATGAAATCAATGAAATCAGAAACGCGCTGATCGCACTGGC
AAATGCGGATAATGGGCAAGACCTGGACGCCCCGAAATCCTCATTCTTTGCAGCAGACGCATTGACTAACCCTGTTCATC
AGCAGTTTGCCCTGAAAACCACCGCCGCGGCTCTGATTTGCTACCTGATCTACACCGCACTGGATTGGCAGGACATTCAT
ACTGCCATGATCACTTGCTATGTTGCCGCACTCGGTACAACAGGTGAGACGGTTCATAAACTGGTCTTGCGGATTATAGG
GTGTCTGATCGGGGCATTGATGGGGGTACTGTCGATTATTTTCATTATTCCCCACATGAGTGATATCGGGCAATTAATGG
CGCTGGTATTTGGCTGCATTCTAGTGGCCGCTTGGGTGTCATGTGGCAGCGAACGTATCGCGTATGCTGGCGTACAGGTT
GGGTTGGCCTTCCTGCTTACCGTGCTGCAAGGTTTTGGGCCAAGTACCGATATGGGTGTCGCACTCGATAGGGTGCTGGG
TATCTTGCTGGGTAATCTGGTGGTGTACTTGATTTTTAGCCGGCTGTGGCCAGTCGCGATTACCGATGCGGTGCATGTAC
ATATTAGTCGCGCCTTGAAGGGGCTGACAAATTTAGCCGCGCTCTCGCCGGATGCCCGGCCTGCAGCGCTCAGAGAGGCC
ACAACTGTCGAGGCGGAGATTACCAAGGCGCAGGAAGAGTTGGCGCTAATTCCCTTTGAGCCAGTACAATTTCGCCCCTC
ACGGAAAGAGTGCGCACGCCTACAGGCCATCTTGGCAGAAATGGGCAAATTGTGCCCTGTTCTGTTTCTACCCACGGAAA
AGTCAGCGTCTGATGTGGAACAACTGCGCCAGCTCTCGGCTGGGAGCGATGCCATGACATTATCGGATGAGCAAGGACAG
AATAGCGGGTCTTTACGGCAAGAGTTATCACCTATTAATCTTACAATTCAACAACGTATAAAGCGGCTTGAGGAACTTCT
AGGAATTTAA

Upstream 100 bases:

>100_bases
CATAATCCGTCAGGCGAAAGCTGACTTAGCCTTTTTCCCAGGGCGGGTGGCGATGGCGTGGCGTGTTGCCGTGCTATGTG
CATTGATGGCGATGATCGCC

Downstream 100 bases:

>100_bases
TGACATGATGACGCACGCAGTATTGACTGCCCGGATAGCCAAAATAAGCCTGACTTGCTCGATATTGAGTTGGAGCCTGT
TGATCGTAGGTTGTGCTACA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 589; Mature: 589

Protein sequence:

>589_residues
MIYGIPESAISCYLIIFVMKPDGVESMVMAVAITILVSLVVGLVFLLIHFTLEAAPLRMAALIVSSFLFLYLGSASKLGP
VGSIIALVIAYVMTLLSNIPMGEVATRGLLYAWLMAVSPMLLIIGFNLFFGRAPQTLLRASLAERLSTVAETLRYPNAAN
MARVGEQLQEGQHEHQQRALFVRIFHLRPSAEAAWLESAVKSSYRLLLVTSALPPTSPEAVRLELAAYCSDAAQAIASGD
LAAPPHFAIEDTSDEINEIRNALIALANADNGQDLDAPKSSFFAADALTNPVHQQFALKTTAAALICYLIYTALDWQDIH
TAMITCYVAALGTTGETVHKLVLRIIGCLIGALMGVLSIIFIIPHMSDIGQLMALVFGCILVAAWVSCGSERIAYAGVQV
GLAFLLTVLQGFGPSTDMGVALDRVLGILLGNLVVYLIFSRLWPVAITDAVHVHISRALKGLTNLAALSPDARPAALREA
TTVEAEITKAQEELALIPFEPVQFRPSRKECARLQAILAEMGKLCPVLFLPTEKSASDVEQLRQLSAGSDAMTLSDEQGQ
NSGSLRQELSPINLTIQQRIKRLEELLGI

Sequences:

>Translated_589_residues
MIYGIPESAISCYLIIFVMKPDGVESMVMAVAITILVSLVVGLVFLLIHFTLEAAPLRMAALIVSSFLFLYLGSASKLGP
VGSIIALVIAYVMTLLSNIPMGEVATRGLLYAWLMAVSPMLLIIGFNLFFGRAPQTLLRASLAERLSTVAETLRYPNAAN
MARVGEQLQEGQHEHQQRALFVRIFHLRPSAEAAWLESAVKSSYRLLLVTSALPPTSPEAVRLELAAYCSDAAQAIASGD
LAAPPHFAIEDTSDEINEIRNALIALANADNGQDLDAPKSSFFAADALTNPVHQQFALKTTAAALICYLIYTALDWQDIH
TAMITCYVAALGTTGETVHKLVLRIIGCLIGALMGVLSIIFIIPHMSDIGQLMALVFGCILVAAWVSCGSERIAYAGVQV
GLAFLLTVLQGFGPSTDMGVALDRVLGILLGNLVVYLIFSRLWPVAITDAVHVHISRALKGLTNLAALSPDARPAALREA
TTVEAEITKAQEELALIPFEPVQFRPSRKECARLQAILAEMGKLCPVLFLPTEKSASDVEQLRQLSAGSDAMTLSDEQGQ
NSGSLRQELSPINLTIQQRIKRLEELLGI
>Mature_589_residues
MIYGIPESAISCYLIIFVMKPDGVESMVMAVAITILVSLVVGLVFLLIHFTLEAAPLRMAALIVSSFLFLYLGSASKLGP
VGSIIALVIAYVMTLLSNIPMGEVATRGLLYAWLMAVSPMLLIIGFNLFFGRAPQTLLRASLAERLSTVAETLRYPNAAN
MARVGEQLQEGQHEHQQRALFVRIFHLRPSAEAAWLESAVKSSYRLLLVTSALPPTSPEAVRLELAAYCSDAAQAIASGD
LAAPPHFAIEDTSDEINEIRNALIALANADNGQDLDAPKSSFFAADALTNPVHQQFALKTTAAALICYLIYTALDWQDIH
TAMITCYVAALGTTGETVHKLVLRIIGCLIGALMGVLSIIFIIPHMSDIGQLMALVFGCILVAAWVSCGSERIAYAGVQV
GLAFLLTVLQGFGPSTDMGVALDRVLGILLGNLVVYLIFSRLWPVAITDAVHVHISRALKGLTNLAALSPDARPAALREA
TTVEAEITKAQEELALIPFEPVQFRPSRKECARLQAILAEMGKLCPVLFLPTEKSASDVEQLRQLSAGSDAMTLSDEQGQ
NSGSLRQELSPINLTIQQRIKRLEELLGI

Specific function: Could be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride [H]

COG id: COG1289

COG function: function code S; Predicted membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MdtO family [H]

Homologues:

Organism=Escherichia coli, GI87082367, Length=465, Percent_Identity=28.1720430107527, Blast_Score=155, Evalue=7e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006726 [H]

Pfam domain/function: PF04632 FUSC [H]

EC number: NA

Molecular weight: Translated: 63487; Mature: 63487

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIYGIPESAISCYLIIFVMKPDGVESMVMAVAITILVSLVVGLVFLLIHFTLEAAPLRMA
CCCCCCHHHHHEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALIVSSFLFLYLGSASKLGPVGSIIALVIAYVMTLLSNIPMGEVATRGLLYAWLMAVSPM
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
LLIIGFNLFFGRAPQTLLRASLAERLSTVAETLRYPNAANMARVGEQLQEGQHEHQQRAL
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
FVRIFHLRPSAEAAWLESAVKSSYRLLLVTSALPPTSPEAVRLELAAYCSDAAQAIASGD
HHHHEECCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCC
LAAPPHFAIEDTSDEINEIRNALIALANADNGQDLDAPKSSFFAADALTNPVHQQFALKT
CCCCCCCEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHH
TAAALICYLIYTALDWQDIHTAMITCYVAALGTTGETVHKLVLRIIGCLIGALMGVLSII
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FIIPHMSDIGQLMALVFGCILVAAWVSCGSERIAYAGVQVGLAFLLTVLQGFGPSTDMGV
HHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
ALDRVLGILLGNLVVYLIFSRLWPVAITDAVHVHISRALKGLTNLAALSPDARPAALREA
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
TTVEAEITKAQEELALIPFEPVQFRPSRKECARLQAILAEMGKLCPVLFLPTEKSASDVE
HHHHHHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHH
QLRQLSAGSDAMTLSDEQGQNSGSLRQELSPINLTIQQRIKRLEELLGI
HHHHHCCCCCCEEECCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIYGIPESAISCYLIIFVMKPDGVESMVMAVAITILVSLVVGLVFLLIHFTLEAAPLRMA
CCCCCCHHHHHEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALIVSSFLFLYLGSASKLGPVGSIIALVIAYVMTLLSNIPMGEVATRGLLYAWLMAVSPM
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
LLIIGFNLFFGRAPQTLLRASLAERLSTVAETLRYPNAANMARVGEQLQEGQHEHQQRAL
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
FVRIFHLRPSAEAAWLESAVKSSYRLLLVTSALPPTSPEAVRLELAAYCSDAAQAIASGD
HHHHEECCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCC
LAAPPHFAIEDTSDEINEIRNALIALANADNGQDLDAPKSSFFAADALTNPVHQQFALKT
CCCCCCCEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHH
TAAALICYLIYTALDWQDIHTAMITCYVAALGTTGETVHKLVLRIIGCLIGALMGVLSII
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FIIPHMSDIGQLMALVFGCILVAAWVSCGSERIAYAGVQVGLAFLLTVLQGFGPSTDMGV
HHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
ALDRVLGILLGNLVVYLIFSRLWPVAITDAVHVHISRALKGLTNLAALSPDARPAALREA
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
TTVEAEITKAQEELALIPFEPVQFRPSRKECARLQAILAEMGKLCPVLFLPTEKSASDVE
HHHHHHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHH
QLRQLSAGSDAMTLSDEQGQNSGSLRQELSPINLTIQQRIKRLEELLGI
HHHHHCCCCCCEEECCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]