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The map label for this gene is shlB [H]

Identifier: 218927795

GI number: 218927795

Start: 647586

End: 649274

Strand: Direct

Name: shlB [H]

Synonym: YPO0598

Alternate gene names: 218927795

Gene position: 647586-649274 (Clockwise)

Preceding gene: 218927788

Following gene: 218927796

Centisome position: 13.92

GC content: 54.17

Gene sequence:

>1689_bases
ATGTCGCGTTTTTATTATTCTATATTAGTGGCTGGCGTATTATTGAAAATAGTGGCTATTCCAGATGCCAGTTATGGCGC
GGAATTAGCGCCCGTTCAACAAAGTATTCACCAACAGGAGCGGCAACGGGCACTTGAAGAGCGCCTGGCTCCGCCGACGC
CGGATGTGCGCTTATCTGCGCCCTCGGCCTTTTTTAGCCGTATTATTTTTCCGCTGGAGACACCCTGTTTTGTTATTAAT
CGGATAAAAATCAGTGGGGCCGAGCCATTGCCCCGTTGGTTGCCGTTGCAACGCATTGCCGATCAAGCGCAAGGCCAGTG
TCTGGGGGCCAAGGGCATTAACCTGCTAATGAGCCAAATGCAGAACCGTTTGGTCGATCACGGCTATGTGACTACCCGAG
TGCTGGCCCCACAGCAGGATTTAAACAGCGGCACGCTGGCGCTAAACGTCGTGCCCGGCAAAATACGCGGTGTGGAACTG
ACGCCAGACAGTAATAGGTATGTCACGTTATTCAGCGCTTTTCCTGCCCGTGCCGGGACGCTGTTGGATTTACGCGATAT
CGAACAAGGCTTGGAAAATCTACAGCGTGTTCCCACGGTGCAAGCCAATATGGTGTTGATCCCAGGCTCTGCCCCCGGTG
AGACGGATATCATTCTGAACTGGCAACAGCGAAAAATGTGGCGGCTGGCAGCCTCACTGGATGATTCGGGTACCCGCAGC
ACTGGCCGCTATCAAGGGGGGGCGACGTTGTTTCTGGATAACCCGCTTTCTCTGAGTGATCTTTTTTATGTCTCAGCTGG
TGGCGCACTGCAACGCCGTGGCGATAAAGGCACGAATAATCTGACCGGCCATTACTCATTGCCATTCGGTTATTGGACCG
CAGGCATGACCGCCAGCCGTTATGACTATTACCAGGCCGTTGCGGGCCTGAATGGCGATATCAACTACCGAGGTGAAAGT
GAGAACGTGGCGTTCCAACTCAGCCGGTTGTTGCACCGTAATGCCAGCCAGAAAACCACCTTTACCTACGATGTGCTAAC
CCGTTCGTCGAAAAACTATATCAACGATACCGAAGTGGAAGTACAGCGCCGCCGCACCTCGGCCTGGCGGATCGGGCTAC
AACACCGCCACTTTATCTCGCAGGCGATTTTGGATGCCGGTATCAGCTATCAGCGTGGCACCCGCTGGTTTGGTGCCATA
CCCGCGCAGGAAGAGTATTTCGGCGAAGCCACCGCCCTGAGCAAAATTCTGCGATTGAATGCGCAACTGGATATTCCTTT
TGTGGTTATGGCGCAAAACCTCCATTACAACCTGCAATATCAGCGCCAAAGTACCAACACGCCACTGACGCCGCAGGATC
AGTTCTCCATTGGTGGCCGCTGGTCGGTGCGTGGTTTTAATGGTGAGCGCACGCTGATTGCCGATCGCGGCTGGTGGGTG
CGCAATGATATCGGCTGGTATCTGCCGCTACCGGGGCATGAGCTGTATGTCGGTGTGGATTACGGCGAAGTCGGTGGTCG
TAGTGGCGCTTATCTGTTAGGCCGCCATTTGGCGGGCAGTGCGGTCGGGGTACGTGGCAACGTACTGAATACCCGCTATG
ACCTGTTTGCGGGGAAACCGCTCTCTAAACCTAATGGTTTCAAAACCGATTCGCTGGCGGTGGGTTTTAACCTGAATTGG
CTGTACTGA

Upstream 100 bases:

>100_bases
TTAACTATAAAATTATTAGGAATCACGTCATTATGATTATCGTGGCGTAACGTAATGATTATGTTTATGTACCCCAAGCT
CTTGGGGAAGGGAACTCCTC

Downstream 100 bases:

>100_bases
TGTGTCCGATTAACGTTAATTAACTTAACTCTCTGGGATGAGCCATGAATAAAAACCTGTACCGTATTGTTTTTAATCAA
GCGCGCGGCATGTTGATGGT

Product: putative hemolysin activator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 562; Mature: 561

Protein sequence:

>562_residues
MSRFYYSILVAGVLLKIVAIPDASYGAELAPVQQSIHQQERQRALEERLAPPTPDVRLSAPSAFFSRIIFPLETPCFVIN
RIKISGAEPLPRWLPLQRIADQAQGQCLGAKGINLLMSQMQNRLVDHGYVTTRVLAPQQDLNSGTLALNVVPGKIRGVEL
TPDSNRYVTLFSAFPARAGTLLDLRDIEQGLENLQRVPTVQANMVLIPGSAPGETDIILNWQQRKMWRLAASLDDSGTRS
TGRYQGGATLFLDNPLSLSDLFYVSAGGALQRRGDKGTNNLTGHYSLPFGYWTAGMTASRYDYYQAVAGLNGDINYRGES
ENVAFQLSRLLHRNASQKTTFTYDVLTRSSKNYINDTEVEVQRRRTSAWRIGLQHRHFISQAILDAGISYQRGTRWFGAI
PAQEEYFGEATALSKILRLNAQLDIPFVVMAQNLHYNLQYQRQSTNTPLTPQDQFSIGGRWSVRGFNGERTLIADRGWWV
RNDIGWYLPLPGHELYVGVDYGEVGGRSGAYLLGRHLAGSAVGVRGNVLNTRYDLFAGKPLSKPNGFKTDSLAVGFNLNW
LY

Sequences:

>Translated_562_residues
MSRFYYSILVAGVLLKIVAIPDASYGAELAPVQQSIHQQERQRALEERLAPPTPDVRLSAPSAFFSRIIFPLETPCFVIN
RIKISGAEPLPRWLPLQRIADQAQGQCLGAKGINLLMSQMQNRLVDHGYVTTRVLAPQQDLNSGTLALNVVPGKIRGVEL
TPDSNRYVTLFSAFPARAGTLLDLRDIEQGLENLQRVPTVQANMVLIPGSAPGETDIILNWQQRKMWRLAASLDDSGTRS
TGRYQGGATLFLDNPLSLSDLFYVSAGGALQRRGDKGTNNLTGHYSLPFGYWTAGMTASRYDYYQAVAGLNGDINYRGES
ENVAFQLSRLLHRNASQKTTFTYDVLTRSSKNYINDTEVEVQRRRTSAWRIGLQHRHFISQAILDAGISYQRGTRWFGAI
PAQEEYFGEATALSKILRLNAQLDIPFVVMAQNLHYNLQYQRQSTNTPLTPQDQFSIGGRWSVRGFNGERTLIADRGWWV
RNDIGWYLPLPGHELYVGVDYGEVGGRSGAYLLGRHLAGSAVGVRGNVLNTRYDLFAGKPLSKPNGFKTDSLAVGFNLNW
LY
>Mature_561_residues
SRFYYSILVAGVLLKIVAIPDASYGAELAPVQQSIHQQERQRALEERLAPPTPDVRLSAPSAFFSRIIFPLETPCFVINR
IKISGAEPLPRWLPLQRIADQAQGQCLGAKGINLLMSQMQNRLVDHGYVTTRVLAPQQDLNSGTLALNVVPGKIRGVELT
PDSNRYVTLFSAFPARAGTLLDLRDIEQGLENLQRVPTVQANMVLIPGSAPGETDIILNWQQRKMWRLAASLDDSGTRST
GRYQGGATLFLDNPLSLSDLFYVSAGGALQRRGDKGTNNLTGHYSLPFGYWTAGMTASRYDYYQAVAGLNGDINYRGESE
NVAFQLSRLLHRNASQKTTFTYDVLTRSSKNYINDTEVEVQRRRTSAWRIGLQHRHFISQAILDAGISYQRGTRWFGAIP
AQEEYFGEATALSKILRLNAQLDIPFVVMAQNLHYNLQYQRQSTNTPLTPQDQFSIGGRWSVRGFNGERTLIADRGWWVR
NDIGWYLPLPGHELYVGVDYGEVGGRSGAYLLGRHLAGSAVGVRGNVLNTRYDLFAGKPLSKPNGFKTDSLAVGFNLNWL
Y

Specific function: Member of a two partner secretion pathway (TPS) in which it mediates the secretion of hemolysin [H]

COG id: COG2831

COG function: function code U; Hemolysin activation/secretion protein

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tpsB (TC 1.B.20) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005565
- InterPro:   IPR013686 [H]

Pfam domain/function: PF08479 POTRA_2; PF03865 ShlB [H]

EC number: NA

Molecular weight: Translated: 62638; Mature: 62507

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRFYYSILVAGVLLKIVAIPDASYGAELAPVQQSIHQQERQRALEERLAPPTPDVRLSA
CCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECC
PSAFFSRIIFPLETPCFVINRIKISGAEPLPRWLPLQRIADQAQGQCLGAKGINLLMSQM
CHHHHHHHHCCCCCCEEEEEEEEECCCCCCCHHCCHHHHHHHHCCCEECCCHHHHHHHHH
QNRLVDHGYVTTRVLAPQQDLNSGTLALNVVPGKIRGVELTPDSNRYVTLFSAFPARAGT
HHHHHCCCCEEEEEECCCCCCCCCEEEEEEECCCEEEEEECCCCCCEEEEEEECCCCCCC
LLDLRDIEQGLENLQRVPTVQANMVLIPGSAPGETDIILNWQQRKMWRLAASLDDSGTRS
EEEHHHHHHHHHHHHHCCCEECCEEEECCCCCCCCEEEEEHHHHHHHHHHHCCCCCCCCC
TGRYQGGATLFLDNPLSLSDLFYVSAGGALQRRGDKGTNNLTGHYSLPFGYWTAGMTASR
CCCCCCCEEEEECCCCCCCCEEEEECCCHHHCCCCCCCCCCCEEEECCCHHHCCCCCCHH
YDYYQAVAGLNGDINYRGESENVAFQLSRLLHRNASQKTTFTYDVLTRSSKNYINDTEVE
HHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCCCHHH
VQRRRTSAWRIGLQHRHFISQAILDAGISYQRGTRWFGAIPAQEEYFGEATALSKILRLN
HHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCEEEECCCCCHHHCCHHHHHHHHHHHC
AQLDIPFVVMAQNLHYNLQYQRQSTNTPLTPQDQFSIGGRWSVRGFNGERTLIADRGWWV
CCCCCCEEEEEECCEEEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCEEEEECCCEEE
RNDIGWYLPLPGHELYVGVDYGEVGGRSGAYLLGRHLAGSAVGVRGNVLNTRYDLFAGKP
ECCCCEEEECCCCEEEEEECHHCCCCCCCCEEEEHHHCCCEEEECCCEECCEEEEEECCC
LSKPNGFKTDSLAVGFNLNWLY
CCCCCCCCCCCEEEEEEEEEEC
>Mature Secondary Structure 
SRFYYSILVAGVLLKIVAIPDASYGAELAPVQQSIHQQERQRALEERLAPPTPDVRLSA
CHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECC
PSAFFSRIIFPLETPCFVINRIKISGAEPLPRWLPLQRIADQAQGQCLGAKGINLLMSQM
CHHHHHHHHCCCCCCEEEEEEEEECCCCCCCHHCCHHHHHHHHCCCEECCCHHHHHHHHH
QNRLVDHGYVTTRVLAPQQDLNSGTLALNVVPGKIRGVELTPDSNRYVTLFSAFPARAGT
HHHHHCCCCEEEEEECCCCCCCCCEEEEEEECCCEEEEEECCCCCCEEEEEEECCCCCCC
LLDLRDIEQGLENLQRVPTVQANMVLIPGSAPGETDIILNWQQRKMWRLAASLDDSGTRS
EEEHHHHHHHHHHHHHCCCEECCEEEECCCCCCCCEEEEEHHHHHHHHHHHCCCCCCCCC
TGRYQGGATLFLDNPLSLSDLFYVSAGGALQRRGDKGTNNLTGHYSLPFGYWTAGMTASR
CCCCCCCEEEEECCCCCCCCEEEEECCCHHHCCCCCCCCCCCEEEECCCHHHCCCCCCHH
YDYYQAVAGLNGDINYRGESENVAFQLSRLLHRNASQKTTFTYDVLTRSSKNYINDTEVE
HHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCCCHHH
VQRRRTSAWRIGLQHRHFISQAILDAGISYQRGTRWFGAIPAQEEYFGEATALSKILRLN
HHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCEEEECCCCCHHHCCHHHHHHHHHHHC
AQLDIPFVVMAQNLHYNLQYQRQSTNTPLTPQDQFSIGGRWSVRGFNGERTLIADRGWWV
CCCCCCEEEEEECCEEEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCEEEEECCCEEE
RNDIGWYLPLPGHELYVGVDYGEVGGRSGAYLLGRHLAGSAVGVRGNVLNTRYDLFAGKP
ECCCCEEEECCCCEEEEEECHHCCCCCCCCEEEEHHHCCCEEEECCCEECCEEEEEECCC
LSKPNGFKTDSLAVGFNLNWLY
CCCCCCCCCCCEEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3290200 [H]