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The map label for this gene is secM [H]

Identifier: 218927759

GI number: 218927759

Start: 608765

End: 609298

Strand: Direct

Name: secM [H]

Synonym: YPO0563

Alternate gene names: 218927759

Gene position: 608765-609298 (Clockwise)

Preceding gene: 218927757

Following gene: 218927760

Centisome position: 13.08

GC content: 50.19

Gene sequence:

>534_bases
GTGATCGGTATTCTAAATCGTTGGCGACAATTTGGCAGACGTTATTTCTGGCCGCATCTCCTGTTGGGGATGGTCGCGGC
GAGTCTTGGTGTGCCATTAAATCTGTCTGGCGTTCCAGACCATGCGGCATTAGCGAACACATCATCCAGCCAAAGTCGTC
AGAATCATGGTACGACAAACTTCAACAGTTTGGCACTGTTGCATGACATACACCGTCGCCTCTCATTCAGTGTAGATTAC
TGGCAACAGCATGCCCTGCGCACGGTCATCCGTCACCTCTCTTTTGCTCTGGCACCACAAGCGGCATATGCACGCGTACA
AGAAGTCGCCGAAACAGAACGGGTTGCTCCATCAAAAATTCAGCAACTCGCGTTACTGGATACGCTAAATGCACTACTGA
CGCATGAATTTAAGCCACCGGCCATTATTCGCTATACAGAACAGGTTGAACGGCCTGTTCTGTCGCCATATAAACCTGGG
CTCTGGCTTGCTCAAGTACAAGGTATTCGTGCCGGTCCTGCCAACTTAAGCTAA

Upstream 100 bases:

>100_bases
TAGCGGTCCGTTTTCTGCTGCAACCGCATCATCGAACAGAACATCTAATAATTGTGGGCGGTTTTCACGCATTGACAAGG
CTCCGGCGGATTTTAAACTC

Downstream 100 bases:

>100_bases
TTATTCTCTTGGTTTATCCCAATTTTATACAACCTTTGGCCGCCGGTTTGGTGGTCTTGTAAGAGATATTAAGAATCATG
CTAATTAAATTATTAACCAA

Product: SecA regulator SecM

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 177; Mature: 177

Protein sequence:

>177_residues
MIGILNRWRQFGRRYFWPHLLLGMVAASLGVPLNLSGVPDHAALANTSSSQSRQNHGTTNFNSLALLHDIHRRLSFSVDY
WQQHALRTVIRHLSFALAPQAAYARVQEVAETERVAPSKIQQLALLDTLNALLTHEFKPPAIIRYTEQVERPVLSPYKPG
LWLAQVQGIRAGPANLS

Sequences:

>Translated_177_residues
MIGILNRWRQFGRRYFWPHLLLGMVAASLGVPLNLSGVPDHAALANTSSSQSRQNHGTTNFNSLALLHDIHRRLSFSVDY
WQQHALRTVIRHLSFALAPQAAYARVQEVAETERVAPSKIQQLALLDTLNALLTHEFKPPAIIRYTEQVERPVLSPYKPG
LWLAQVQGIRAGPANLS
>Mature_177_residues
MIGILNRWRQFGRRYFWPHLLLGMVAASLGVPLNLSGVPDHAALANTSSSQSRQNHGTTNFNSLALLHDIHRRLSFSVDY
WQQHALRTVIRHLSFALAPQAAYARVQEVAETERVAPSKIQQLALLDTLNALLTHEFKPPAIIRYTEQVERPVLSPYKPG
LWLAQVQGIRAGPANLS

Specific function: Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm, cytosol. Periplasm (By similarity). Note=The active form is cytosolic, while the periplasmic form is rapidly degraded, mainly by the tail-specific protease (By similarity) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secM family [H]

Homologues:

Organism=Escherichia coli, GI87081686, Length=180, Percent_Identity=48.8888888888889, Blast_Score=148, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009502
- ProDom:   PD089227 [H]

Pfam domain/function: PF06558 SecM [H]

EC number: NA

Molecular weight: Translated: 19847; Mature: 19847

Theoretical pI: Translated: 10.82; Mature: 10.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGILNRWRQFGRRYFWPHLLLGMVAASLGVPLNLSGVPDHAALANTSSSQSRQNHGTTN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCHHHHHHCCCCC
FNSLALLHDIHRRLSFSVDYWQQHALRTVIRHLSFALAPQAAYARVQEVAETERVAPSKI
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHH
QQLALLDTLNALLTHEFKPPAIIRYTEQVERPVLSPYKPGLWLAQVQGIRAGPANLS
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MIGILNRWRQFGRRYFWPHLLLGMVAASLGVPLNLSGVPDHAALANTSSSQSRQNHGTTN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCHHHHHHCCCCC
FNSLALLHDIHRRLSFSVDYWQQHALRTVIRHLSFALAPQAAYARVQEVAETERVAPSKI
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHH
QQLALLDTLNALLTHEFKPPAIIRYTEQVERPVLSPYKPGLWLAQVQGIRAGPANLS
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA