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The map label for this gene is djlA

Identifier: 218927694

GI number: 218927694

Start: 528654

End: 529487

Strand: Direct

Name: djlA

Synonym: YPO0496

Alternate gene names: 218927694

Gene position: 528654-529487 (Clockwise)

Preceding gene: 218927687

Following gene: 218927697

Centisome position: 11.36

GC content: 50.0

Gene sequence:

>834_bases
ATGCGGTATTGGGGAAAACTGCTCGGTCTGGTATTGGGCGTAATGTATGCTCCTGGCGTTGTTGGAGCGCTATTGGGGCT
ACTTGTTGGCCATATGGTAGACAGGGCGCTTGGCGCAAAACGCCGCGGTTTTTTTGCTGATCAACAGACACGGCAATCAC
TTTTTTTCCGTACCACTTTTCAAGTCATGGGGCATTTAACCAAGGCTAAAGGGCGTGTTACGGAGGTTGATATCCAACTC
GCCAGCCAACTAATGGATAGGATGCAATTACATGGCGCTGCCAGAACAGCGGCACAGCAAGCGTTTCGTGAAGGGAAAGA
AAGCCACTTTCCGTTGCGAAAGGCGTTGCAGGAATTTCGCCGTGTTTGTTTTGGCCGTTTTGACTTAATTCGGATATTTC
TGGAAATTCAATTACAGGCCGCATTTGCCGATGGTTCCTTGCATCCTAACGAGCGTCAAGTGCTGTATGTGATTGCTGAA
GAGTTAGGGATCTCCCGTGGTCAATTCGATCAATTCCTGCGTATGTTCGATGGGGGGCGTCAATTTGGTGGTCATGGAGG
GTGGCAAGGCCAGCAAGGGGGCTATTCCCAAAGTGGTTACCAGCGAGCTTCCCAGGGCCCGACTCTGGAAGATGCTTGTA
AAGTCTTGGGGGTAAATAGCAGTGATGACAGTGTGGCCATCAAGCGTGCTTACCGTAAGTTAATGGGGGAACATCACCCG
GATAAGCTGGTTGCCAAAGGGTTACCCCCAGAGATGATGGAAATGGCGAAGCAAAAAGCGCAGGAAATTCAGGCTGCGTA
TGATTTGATCAAACGCGAGAAAGGGTTTAAGTGA

Upstream 100 bases:

>100_bases
TTAAATCTGGCCGTTTACACGTCTCGCCGTTAGGCGCTGAGCTAAATGCCGAGTATGATAATGCAAATTTTGGCTGACGG
CATGGTGAATTGAGGAGTAT

Downstream 100 bases:

>100_bases
CTTTTTTATTGATCAGTAAGTGACTGGGGTGAACGAAAGCAGCCAATACACACGCAGTTTGAAGTATGACGGGTATATAG
TGATCGGTTTCAGTTGCTGG

Product: Dna-J like membrane chaperone protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
MRYWGKLLGLVLGVMYAPGVVGALLGLLVGHMVDRALGAKRRGFFADQQTRQSLFFRTTFQVMGHLTKAKGRVTEVDIQL
ASQLMDRMQLHGAARTAAQQAFREGKESHFPLRKALQEFRRVCFGRFDLIRIFLEIQLQAAFADGSLHPNERQVLYVIAE
ELGISRGQFDQFLRMFDGGRQFGGHGGWQGQQGGYSQSGYQRASQGPTLEDACKVLGVNSSDDSVAIKRAYRKLMGEHHP
DKLVAKGLPPEMMEMAKQKAQEIQAAYDLIKREKGFK

Sequences:

>Translated_277_residues
MRYWGKLLGLVLGVMYAPGVVGALLGLLVGHMVDRALGAKRRGFFADQQTRQSLFFRTTFQVMGHLTKAKGRVTEVDIQL
ASQLMDRMQLHGAARTAAQQAFREGKESHFPLRKALQEFRRVCFGRFDLIRIFLEIQLQAAFADGSLHPNERQVLYVIAE
ELGISRGQFDQFLRMFDGGRQFGGHGGWQGQQGGYSQSGYQRASQGPTLEDACKVLGVNSSDDSVAIKRAYRKLMGEHHP
DKLVAKGLPPEMMEMAKQKAQEIQAAYDLIKREKGFK
>Mature_277_residues
MRYWGKLLGLVLGVMYAPGVVGALLGLLVGHMVDRALGAKRRGFFADQQTRQSLFFRTTFQVMGHLTKAKGRVTEVDIQL
ASQLMDRMQLHGAARTAAQQAFREGKESHFPLRKALQEFRRVCFGRFDLIRIFLEIQLQAAFADGSLHPNERQVLYVIAE
ELGISRGQFDQFLRMFDGGRQFGGHGGWQGQQGGYSQSGYQRASQGPTLEDACKVLGVNSSDDSVAIKRAYRKLMGEHHP
DKLVAKGLPPEMMEMAKQKAQEIQAAYDLIKREKGFK

Specific function: Regulatory dnaK co-chaperone. Direct interaction between dnaK and djlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the rcsB/rcsC phosphotransfer sig

COG id: COG1076

COG function: function code O; DnaJ-domain-containing proteins 1

Gene ontology:

Cell location: Cell inner membrane; Single-pass type III membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain

Homologues:

Organism=Escherichia coli, GI1786241, Length=277, Percent_Identity=68.2310469314079, Blast_Score=376, Evalue=1e-105,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DJLA_YERPE (Q74Q30)

Other databases:

- EMBL:   AL590842
- EMBL:   AE009952
- EMBL:   AE017042
- PIR:   AF0061
- RefSeq:   NP_670976.1
- RefSeq:   NP_994954.1
- RefSeq:   YP_002345569.1
- ProteinModelPortal:   Q74Q30
- SMR:   Q74Q30
- GeneID:   1148626
- GeneID:   1173341
- GeneID:   2763372
- GenomeReviews:   AE009952_GR
- GenomeReviews:   AE017042_GR
- GenomeReviews:   AL590842_GR
- KEGG:   ype:YPO0496
- KEGG:   ypk:y3679
- KEGG:   ypm:YP_3683
- HOGENOM:   HBG508481
- OMA:   LRACWRM
- ProtClustDB:   PRK09430
- BioCyc:   YPES187410:Y3679-MONOMER
- BioCyc:   YPES214092:YPO0496-MONOMER
- HAMAP:   MF_01153
- InterPro:   IPR001623
- InterPro:   IPR007791
- InterPro:   IPR015609
- InterPro:   IPR003095
- Gene3D:   G3DSA:1.10.287.110
- PANTHER:   PTHR11821
- PRINTS:   PR00625
- SMART:   SM00271

Pfam domain/function: PF00226 DnaJ; PF05099 TerB; SSF46565 DnaJ_N

EC number: NA

Molecular weight: Translated: 31065; Mature: 31065

Theoretical pI: Translated: 10.37; Mature: 10.37

Prosite motif: PS00636 DNAJ_1; PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x4ed55df8)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCH
>Mature Secondary Structure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HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430