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The map label for this gene is dapB [H]

Identifier: 218927678

GI number: 218927678

Start: 510813

End: 511634

Strand: Direct

Name: dapB [H]

Synonym: YPO0480

Alternate gene names: 218927678

Gene position: 510813-511634 (Clockwise)

Preceding gene: 218927677

Following gene: 218927679

Centisome position: 10.98

GC content: 50.24

Gene sequence:

>822_bases
ATGACTGATTCAACAATTCGTATTGCTATTGTCGGCGCGGGTGGACGGATGGGGCGGCAATTAATTCAAGCCGTTACGCA
GATGGAAGGCGTTGTCTTAGGGGCGGCTATCGAGCGTAAAGGGTCCACGTTGGTAGGCAGTGATGCGGGTGAGCTGGCGG
GTGTTGGCTTGTTAAATGTCATTGTTGGCGATGATTTATCCCAACTTACTGATAATTTTGACGTACTGATCGACTTTACC
CGCCCAGAAGGTACGTTGGAACATTTAGCTATTTGCCGTCAGCATCGGAAAGCGATGGTGATTGGTACCACGGGTTTTGA
TGAGGCAGGTAAAGCGGCCATTAGTGAGGCTGCGGCAGACATTGGTATTGTGTTCGCAGCGAACTTCAGTGTTGGGGTGA
ATGTGGTACTGAAATTGCTGGAAAAGGCGGCGAAAGTCATGGGCGATTATACCGATATTGAAATTATCGAAGCCCATCAC
CGCCACAAAGTGGATGCACCATCAGGAACGGCGCTGGCAATGGGTGAGGCGATTGCTGATGCTATGGGGCGCTCCTTGAA
AGATTGTGCAGTTTATAGCCGTGAAGGCTATACCGGTGAGCGTAAACCGGGGACCATCGGTTTCGCGACCGTGCGTGCTG
GCGATATTGTGGGTGAACACACGGCAATGTTTGCTGATATCGGCGAACGGGTTGAGATCACTCACAAAGCGACGAGCCGG
ATGACTTTTGCCCATGGTGCGGTTAAGTCTGCCATTTGGCTTGGTAAGCATGATAATGGCTTGTTTGATATGCGTGATGT
ACTGAATCTTAACGAACTTTAA

Upstream 100 bases:

>100_bases
ATCATTTTTTTCTAATACAGATTAAATAGGCTGGTAGAGTCAATAGCCGGCGGCTAATCTGAACCCTGGTCAGGGTAGAG
GACACATTTTAAGGGGACGT

Downstream 100 bases:

>100_bases
TGCTTTAAATTACAACCAGTGATGTGGTTGTTTTTATCATAATCATTTGATAATAGGGCAATATTTTATTATCCTTTTTT
ATTTTAAATTTAAAATAAGC

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR [H]

Number of amino acids: Translated: 273; Mature: 272

Protein sequence:

>273_residues
MTDSTIRIAIVGAGGRMGRQLIQAVTQMEGVVLGAAIERKGSTLVGSDAGELAGVGLLNVIVGDDLSQLTDNFDVLIDFT
RPEGTLEHLAICRQHRKAMVIGTTGFDEAGKAAISEAAADIGIVFAANFSVGVNVVLKLLEKAAKVMGDYTDIEIIEAHH
RHKVDAPSGTALAMGEAIADAMGRSLKDCAVYSREGYTGERKPGTIGFATVRAGDIVGEHTAMFADIGERVEITHKATSR
MTFAHGAVKSAIWLGKHDNGLFDMRDVLNLNEL

Sequences:

>Translated_273_residues
MTDSTIRIAIVGAGGRMGRQLIQAVTQMEGVVLGAAIERKGSTLVGSDAGELAGVGLLNVIVGDDLSQLTDNFDVLIDFT
RPEGTLEHLAICRQHRKAMVIGTTGFDEAGKAAISEAAADIGIVFAANFSVGVNVVLKLLEKAAKVMGDYTDIEIIEAHH
RHKVDAPSGTALAMGEAIADAMGRSLKDCAVYSREGYTGERKPGTIGFATVRAGDIVGEHTAMFADIGERVEITHKATSR
MTFAHGAVKSAIWLGKHDNGLFDMRDVLNLNEL
>Mature_272_residues
TDSTIRIAIVGAGGRMGRQLIQAVTQMEGVVLGAAIERKGSTLVGSDAGELAGVGLLNVIVGDDLSQLTDNFDVLIDFTR
PEGTLEHLAICRQHRKAMVIGTTGFDEAGKAAISEAAADIGIVFAANFSVGVNVVLKLLEKAAKVMGDYTDIEIIEAHHR
HKVDAPSGTALAMGEAIADAMGRSLKDCAVYSREGYTGERKPGTIGFATVRAGDIVGEHTAMFADIGERVEITHKATSRM
TFAHGAVKSAIWLGKHDNGLFDMRDVLNLNEL

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786214, Length=273, Percent_Identity=79.4871794871795, Blast_Score=421, Evalue=1e-119,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040 [H]

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N [H]

EC number: =1.3.1.26 [H]

Molecular weight: Translated: 28888; Mature: 28757

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDSTIRIAIVGAGGRMGRQLIQAVTQMEGVVLGAAIERKGSTLVGSDAGELAGVGLLNV
CCCCEEEEEEEECCCHHHHHHHHHHHHHCCEEEEEEHHCCCCEEECCCCCHHHHHHHEEE
IVGDDLSQLTDNFDVLIDFTRPEGTLEHLAICRQHRKAMVIGTTGFDEAGKAAISEAAAD
ECCCCHHHHCCCCEEEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHC
IGIVFAANFSVGVNVVLKLLEKAAKVMGDYTDIEIIEAHHRHKVDAPSGTALAMGEAIAD
EEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHCCCCCCCCCCHHHHHHHHHH
AMGRSLKDCAVYSREGYTGERKPGTIGFATVRAGDIVGEHTAMFADIGERVEITHKATSR
HHCCCHHHHHHCCCCCCCCCCCCCCEEEEEEECCCHHCHHHHHHHHCCCEEEEEEHHHHH
MTFAHGAVKSAIWLGKHDNGLFDMRDVLNLNEL
HHHHHHHHHHHEEECCCCCCCCHHHHHHCCCCC
>Mature Secondary Structure 
TDSTIRIAIVGAGGRMGRQLIQAVTQMEGVVLGAAIERKGSTLVGSDAGELAGVGLLNV
CCCEEEEEEEECCCHHHHHHHHHHHHHCCEEEEEEHHCCCCEEECCCCCHHHHHHHEEE
IVGDDLSQLTDNFDVLIDFTRPEGTLEHLAICRQHRKAMVIGTTGFDEAGKAAISEAAAD
ECCCCHHHHCCCCEEEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHC
IGIVFAANFSVGVNVVLKLLEKAAKVMGDYTDIEIIEAHHRHKVDAPSGTALAMGEAIAD
EEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHCCCCCCCCCCHHHHHHHHHH
AMGRSLKDCAVYSREGYTGERKPGTIGFATVRAGDIVGEHTAMFADIGERVEITHKATSR
HHCCCHHHHHHCCCCCCCCCCCCCCEEEEEEECCCHHCHHHHHHHHCCCEEEEEEHHHHH
MTFAHGAVKSAIWLGKHDNGLFDMRDVLNLNEL
HHHHHHHHHHHEEECCCCCCCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA