BacMap

Definition	Sulfolobus tokodaii str. 7 chromosome, complete genome.
Accession	NC_003106
Length	2,694,756

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The map label for this gene is yvrD [H]

Identifier: 15921565

GI number: 15921565

Start: 1299285

End: 1300082

Strand: Direct

Name: yvrD [H]

Synonym: ST1299

Alternate gene names: 15921565

Gene position: 1299285-1300082 (Clockwise)

Preceding gene: 15921564

Following gene: 15921566

Centisome position: 48.22

GC content: 32.08

Gene sequence:

>798_bases
ATGAATGTCGATATAAACGGTAAAAGAGTCTTAATAACTGCATCCACTGAAGGAATAGGTAAAGGTCTAGCAAGAACCCT
ATCACGAGAAGGATGTAAAATTATTATTACTTCTAGGAATGAACATAAGGTTAAATCTACTGTTGAAGAGCTGAAAAAAT
ACAACCCTGAAGTTTACGGTTACGTATCAGATTTAACCAATTATTCAAACTTAGAAGCCTTAGTTAAATTTATGTTAGAA
AAAATCGGAGGCATTGATGTTCTCATTTTTAATTCTGGAAATCCTCCTTCTGAACCTTCTTATTTTGATGAAACTTCAAT
AGAGGACTGGGAGTATTCTGTTAAACTCTATTTACTAAGTGCAATAAAACTTACTAAACTGGTTTTGCCCTATATGAAGT
CGCAAAGATGGGGCAGGATTTTATATTTATCTTCATGGACAATTAAACAACCTCAAAGAATTTTTGTCTTAGCAGATGTG
TCCAGATCTTCAATTGTTCAATTAACTAAGATTCTCTCTAAAGAACTAGGAAGCTATAACATTACTGTTAATACAATACT
AATGGGAAGTTTTGAGACAGAAGGGGCAAAAAGAAGTCTTAAAAAATTAGCAGAGAAACAAAAGATAGATTTCGAAGAGT
TATGGAAAAAGGAAGTAATAGAAAGATCTCCGTTAAAAAGAACTGGTGATATTGAAAAAGAATTAGGTTCGCTTATTGCA
TATCTAATTTCTGATTATGCTTCATATATAACAGGTTCCGTAATACAAATAGATGGAGGTACTAGTGATGCAATATAA

Upstream 100 bases:

>100_bases
AAAATTACCAGCTTATTTCCATAGATTTAATATCTACTGTAGGCAAAAGTAAACTAGTAGCCGACACTTATATTAAAAAG
AATTTTTCATAATTAATGAG

Downstream 100 bases:

>100_bases
GTATTAAAGGACTCCTTTAACTTTGGCTTAAGTTACTCATGGTATTACACCTTACAATACTTGACAAAATGTTTATAAAA
TTGTTTGAACAAGTACTATA

Product: reductase

Products: 3-oxoacyl-[acyl-carrier protein]; NADPH; H+

Alternate protein names: NA

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MNVDINGKRVLITASTEGIGKGLARTLSREGCKIIITSRNEHKVKSTVEELKKYNPEVYGYVSDLTNYSNLEALVKFMLE
KIGGIDVLIFNSGNPPSEPSYFDETSIEDWEYSVKLYLLSAIKLTKLVLPYMKSQRWGRILYLSSWTIKQPQRIFVLADV
SRSSIVQLTKILSKELGSYNITVNTILMGSFETEGAKRSLKKLAEKQKIDFEELWKKEVIERSPLKRTGDIEKELGSLIA
YLISDYASYITGSVIQIDGGTSDAI

Sequences:

>Translated_265_residues
MNVDINGKRVLITASTEGIGKGLARTLSREGCKIIITSRNEHKVKSTVEELKKYNPEVYGYVSDLTNYSNLEALVKFMLE
KIGGIDVLIFNSGNPPSEPSYFDETSIEDWEYSVKLYLLSAIKLTKLVLPYMKSQRWGRILYLSSWTIKQPQRIFVLADV
SRSSIVQLTKILSKELGSYNITVNTILMGSFETEGAKRSLKKLAEKQKIDFEELWKKEVIERSPLKRTGDIEKELGSLIA
YLISDYASYITGSVIQIDGGTSDAI
>Mature_265_residues
MNVDINGKRVLITASTEGIGKGLARTLSREGCKIIITSRNEHKVKSTVEELKKYNPEVYGYVSDLTNYSNLEALVKFMLE
KIGGIDVLIFNSGNPPSEPSYFDETSIEDWEYSVKLYLLSAIKLTKLVLPYMKSQRWGRILYLSSWTIKQPQRIFVLADV
SRSSIVQLTKILSKELGSYNITVNTILMGSFETEGAKRSLKKLAEKQKIDFEELWKKEVIERSPLKRTGDIEKELGSLIA
YLISDYASYITGSVIQIDGGTSDAI

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=254, Percent_Identity=31.496062992126, Blast_Score=115, Evalue=4e-26,
Organism=Homo sapiens, GI5031737, Length=249, Percent_Identity=30.5220883534137, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI126723750, Length=259, Percent_Identity=27.4131274131274, Blast_Score=94, Evalue=9e-20,
Organism=Homo sapiens, GI33667109, Length=187, Percent_Identity=31.0160427807487, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI126723191, Length=182, Percent_Identity=30.2197802197802, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI19923817, Length=267, Percent_Identity=25.4681647940075, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI7705925, Length=265, Percent_Identity=24.1509433962264, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI4503301, Length=236, Percent_Identity=25.8474576271186, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI66933014, Length=260, Percent_Identity=27.3076923076923, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI59889578, Length=239, Percent_Identity=25.9414225941423, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI4503817, Length=240, Percent_Identity=25.4166666666667, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI7706318, Length=198, Percent_Identity=28.7878787878788, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI32455239, Length=226, Percent_Identity=23.4513274336283, Blast_Score=66, Evalue=4e-11,
Organism=Homo sapiens, GI5031765, Length=226, Percent_Identity=23.4513274336283, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI87082100, Length=262, Percent_Identity=30.9160305343511, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1787905, Length=259, Percent_Identity=25.0965250965251, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1787335, Length=258, Percent_Identity=25.1937984496124, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1790717, Length=254, Percent_Identity=26.7716535433071, Blast_Score=97, Evalue=9e-22,
Organism=Escherichia coli, GI1789208, Length=257, Percent_Identity=24.9027237354086, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1788459, Length=257, Percent_Identity=27.2373540856031, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI87082160, Length=256, Percent_Identity=23.828125, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789057, Length=258, Percent_Identity=24.4186046511628, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1789378, Length=258, Percent_Identity=23.6434108527132, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787545, Length=272, Percent_Identity=23.8970588235294, Blast_Score=61, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17560676, Length=253, Percent_Identity=30.4347826086957, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17561402, Length=258, Percent_Identity=32.1705426356589, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17562910, Length=266, Percent_Identity=31.9548872180451, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17560332, Length=263, Percent_Identity=30.7984790874525, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI115534694, Length=263, Percent_Identity=26.615969581749, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17559104, Length=263, Percent_Identity=28.1368821292776, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17538486, Length=264, Percent_Identity=27.6515151515151, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17560150, Length=264, Percent_Identity=27.2727272727273, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17562904, Length=264, Percent_Identity=28.4090909090909, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17538480, Length=276, Percent_Identity=28.2608695652174, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17568967, Length=199, Percent_Identity=27.1356783919598, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17562906, Length=270, Percent_Identity=27.4074074074074, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17562908, Length=272, Percent_Identity=26.8382352941176, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17562990, Length=264, Percent_Identity=26.1363636363636, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17560220, Length=265, Percent_Identity=25.2830188679245, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17531453, Length=277, Percent_Identity=27.4368231046931, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17551412, Length=268, Percent_Identity=27.6119402985075, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI193204405, Length=268, Percent_Identity=26.4925373134328, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71994604, Length=253, Percent_Identity=23.7154150197628, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI72000259, Length=264, Percent_Identity=26.8939393939394, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17508651, Length=255, Percent_Identity=25.0980392156863, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71994600, Length=254, Percent_Identity=24.0157480314961, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17563726, Length=264, Percent_Identity=25, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17544670, Length=270, Percent_Identity=24.8148148148148, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=261, Percent_Identity=28.735632183908, Blast_Score=78, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6322861, Length=203, Percent_Identity=26.6009852216749, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322227, Length=198, Percent_Identity=28.2828282828283, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21355319, Length=256, Percent_Identity=27.34375, Blast_Score=103, Evalue=9e-23,
Organism=Drosophila melanogaster, GI23397609, Length=253, Percent_Identity=30.0395256916996, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI28571526, Length=257, Percent_Identity=30.7392996108949, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21357041, Length=257, Percent_Identity=30.3501945525292, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24639444, Length=261, Percent_Identity=27.9693486590038, Blast_Score=88, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24644339, Length=268, Percent_Identity=28.3582089552239, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24584748, Length=185, Percent_Identity=28.6486486486486, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI161076933, Length=185, Percent_Identity=28.6486486486486, Blast_Score=71, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24644337, Length=260, Percent_Identity=28.0769230769231, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24640492, Length=146, Percent_Identity=31.5068493150685, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24584744, Length=193, Percent_Identity=27.979274611399, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100

Molecular weight: Translated: 29868; Mature: 29868

Theoretical pI: Translated: 9.04; Mature: 9.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVDINGKRVLITASTEGIGKGLARTLSREGCKIIITSRNEHKVKSTVEELKKYNPEVYG
CCCCCCCCEEEEEECCCHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHCCCCEEE
YVSDLTNYSNLEALVKFMLEKIGGIDVLIFNSGNPPSEPSYFDETSIEDWEYSVKLYLLS
EHHHHCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
AIKLTKLVLPYMKSQRWGRILYLSSWTIKQPQRIFVLADVSRSSIVQLTKILSKELGSYN
HHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEEEECCHHHHHHHHHHHHHHCCCEE
ITVNTILMGSFETEGAKRSLKKLAEKQKIDFEELWKKEVIERSPLKRTGDIEKELGSLIA
EEEEEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
YLISDYASYITGSVIQIDGGTSDAI
HHHHHHHHHHCCCEEEECCCCCCCC
>Mature Secondary Structure
MNVDINGKRVLITASTEGIGKGLARTLSREGCKIIITSRNEHKVKSTVEELKKYNPEVYG
CCCCCCCCEEEEEECCCHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHCCCCEEE
YVSDLTNYSNLEALVKFMLEKIGGIDVLIFNSGNPPSEPSYFDETSIEDWEYSVKLYLLS
EHHHHCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
AIKLTKLVLPYMKSQRWGRILYLSSWTIKQPQRIFVLADVSRSSIVQLTKILSKELGSYN
HHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEEEEEECCHHHHHHHHHHHHHHCCCEE
ITVNTILMGSFETEGAKRSLKKLAEKQKIDFEELWKKEVIERSPLKRTGDIEKELGSLIA
EEEEEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
YLISDYASYITGSVIQIDGGTSDAI
HHHHHHHHHHCCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (3R)-3-hydroxyacyl-[acyl-carrier protein]; NADP+

Specific reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ = 3-oxoacyl-[acyl-carrier protein] + NADPH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]