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The map label for this gene is pdxK [H]

Identifier: 159185237

GI number: 159185237

Start: 2456221

End: 2457096

Strand: Direct

Name: pdxK [H]

Synonym: Atu2487

Alternate gene names: 159185237

Gene position: 2456221-2457096 (Clockwise)

Preceding gene: 159185234

Following gene: 15889755

Centisome position: 86.44

GC content: 61.99

Gene sequence:

>876_bases
ATGCAGGAAAATACACAGGGCGCCGTCATCGTCATTTCCAGCCACGTCATGCGTGGCTCCGTCGGCAACCGCGCCGCCGT
TTTTGCGCTGGAGACCCTCGGTTATCCGGTCTGGGCGGTGCCCACCATCGTCATGCCCTGGCACCCCGGCCACGGCCCAT
CCACCCGCATGCGCTTTCAGGATGACGACTTCGACAAGGCCATGACCGACCTCGGAAACGCCCAATGGATCGGCGAGGTC
AAGGCTGTTCTGACCGGTTATTTCGGCAGTGCCGCGCAGGTCCGCTCCGTCGCAAGGCTGATCCGCAATCTGAAGGAAAA
GAACCCGGCGCTGGTTTACGCCTGCGACCCGGTCATGGGCGATCTGGGCGGGCTTTATATTCCCCTCGAGACCGCCGAAG
CCATCCGGGATCACCTCATCCCGCTTGCCACCGTCGCCACGCCAAACCGTTACGAACTGGCTTGGATGAGCGGCGCGGAA
CTTGAGACCAACAATGCCATCATGGATGCCGCGCTCGCGCTCGGGCCGCCGAAAATGCTGGTCACCTCAGCCGTACCGAT
GATGACGGGCGGCACCGGCAATCTTTACCTCAGCGGCCGCCACGCCCTGCTTGCCGAACACCGCGCCATCGAAAATGCGC
CGAACGGCCTCGGCGACCTGATGTCGGCGCTGTTCCTCGCCCGCCTGCTGGAAGGCGTGGATGATGAAAAGGCGCTGCAA
CTGGCAACAGCCAGCGTCTTCGAAATCCTGGCCCGCACCAAAAAACGCGGGATGAACGAACTGACGCTCGAGACCGACTC
TTCAAGTCTCTCCACACCCATGGCCATGGTGCAGATGCGTCATCTCTTGCATCCTTCACGCAGCAAGCGCAAATAG

Upstream 100 bases:

>100_bases
CTGTGGAAACCGGCCTTGCGATATGTCATGAGAGCGCATCTTGATCTCTAGGCAGGGGCACTTGCGCGCTTCTGCGATGT
TTGAAAGCAAGAAGGCCGTG

Downstream 100 bases:

>100_bases
CGGCTAGAGCATTTCCAAGGAAAAGTGGCCCCCCGGTTTTCCGTCCGGAAATGCGGCAGACAAGGAGTTGGAGCGGTTTC
GCGGTTCGAAGAAAAGCGAA

Product: pyridoxamine kinase

Products: NA

Alternate protein names: PM kinase [H]

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MQENTQGAVIVISSHVMRGSVGNRAAVFALETLGYPVWAVPTIVMPWHPGHGPSTRMRFQDDDFDKAMTDLGNAQWIGEV
KAVLTGYFGSAAQVRSVARLIRNLKEKNPALVYACDPVMGDLGGLYIPLETAEAIRDHLIPLATVATPNRYELAWMSGAE
LETNNAIMDAALALGPPKMLVTSAVPMMTGGTGNLYLSGRHALLAEHRAIENAPNGLGDLMSALFLARLLEGVDDEKALQ
LATASVFEILARTKKRGMNELTLETDSSSLSTPMAMVQMRHLLHPSRSKRK

Sequences:

>Translated_291_residues
MQENTQGAVIVISSHVMRGSVGNRAAVFALETLGYPVWAVPTIVMPWHPGHGPSTRMRFQDDDFDKAMTDLGNAQWIGEV
KAVLTGYFGSAAQVRSVARLIRNLKEKNPALVYACDPVMGDLGGLYIPLETAEAIRDHLIPLATVATPNRYELAWMSGAE
LETNNAIMDAALALGPPKMLVTSAVPMMTGGTGNLYLSGRHALLAEHRAIENAPNGLGDLMSALFLARLLEGVDDEKALQ
LATASVFEILARTKKRGMNELTLETDSSSLSTPMAMVQMRHLLHPSRSKRK
>Mature_291_residues
MQENTQGAVIVISSHVMRGSVGNRAAVFALETLGYPVWAVPTIVMPWHPGHGPSTRMRFQDDDFDKAMTDLGNAQWIGEV
KAVLTGYFGSAAQVRSVARLIRNLKEKNPALVYACDPVMGDLGGLYIPLETAEAIRDHLIPLATVATPNRYELAWMSGAE
LETNNAIMDAALALGPPKMLVTSAVPMMTGGTGNLYLSGRHALLAEHRAIENAPNGLGDLMSALFLARLLEGVDDEKALQ
LATASVFEILARTKKRGMNELTLETDSSSLSTPMAMVQMRHLLHPSRSKRK

Specific function: Phosphorylates B6 vitamers; functions in a salvage pathway. Uses pyridoxamine [H]

COG id: COG2240

COG function: function code H; Pyridoxal/pyridoxine/pyridoxamine kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxine kinase family [H]

Homologues:

Organism=Homo sapiens, GI4505701, Length=265, Percent_Identity=29.0566037735849, Blast_Score=116, Evalue=2e-26,
Organism=Escherichia coli, GI1788758, Length=267, Percent_Identity=29.2134831460674, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1787924, Length=279, Percent_Identity=29.3906810035842, Blast_Score=100, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI17507759, Length=287, Percent_Identity=29.2682926829268, Blast_Score=114, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI17507757, Length=296, Percent_Identity=28.7162162162162, Blast_Score=107, Evalue=7e-24,
Organism=Saccharomyces cerevisiae, GI6320806, Length=230, Percent_Identity=30, Blast_Score=100, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6324354, Length=307, Percent_Identity=25.7328990228013, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI45553007, Length=292, Percent_Identity=27.3972602739726, Blast_Score=118, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013749
- InterPro:   IPR004625 [H]

Pfam domain/function: PF08543 Phos_pyr_kin [H]

EC number: =2.7.1.35 [H]

Molecular weight: Translated: 31532; Mature: 31532

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQENTQGAVIVISSHVMRGSVGNRAAVFALETLGYPVWAVPTIVMPWHPGHGPSTRMRFQ
CCCCCCCEEEEEECHHHHCCCCCCCEEEEHHHHCCCHHHCCEEEECCCCCCCCCCCCCCC
DDDFDKAMTDLGNAQWIGEVKAVLTGYFGSAAQVRSVARLIRNLKEKNPALVYACDPVMG
CCHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEEECCCHHH
DLGGLYIPLETAEAIRDHLIPLATVATPNRYELAWMSGAELETNNAIMDAALALGPPKML
CCCCEEEEHHHHHHHHHHCCCCEEECCCCCEEEEEECCCCCCCCCHHHHHHHHCCCHHHH
VTSAVPMMTGGTGNLYLSGRHALLAEHRAIENAPNGLGDLMSALFLARLLEGVDDEKALQ
HHHCCCEEECCCCCEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHH
LATASVFEILARTKKRGMNELTLETDSSSLSTPMAMVQMRHLLHPSRSKRK
HHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MQENTQGAVIVISSHVMRGSVGNRAAVFALETLGYPVWAVPTIVMPWHPGHGPSTRMRFQ
CCCCCCCEEEEEECHHHHCCCCCCCEEEEHHHHCCCHHHCCEEEECCCCCCCCCCCCCCC
DDDFDKAMTDLGNAQWIGEVKAVLTGYFGSAAQVRSVARLIRNLKEKNPALVYACDPVMG
CCHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEEECCCHHH
DLGGLYIPLETAEAIRDHLIPLATVATPNRYELAWMSGAELETNNAIMDAALALGPPKML
CCCCEEEEHHHHHHHHHHCCCCEEECCCCCEEEEEECCCCCCCCCHHHHHHHHCCCHHHH
VTSAVPMMTGGTGNLYLSGRHALLAEHRAIENAPNGLGDLMSALFLARLLEGVDDEKALQ
HHHCCCEEECCCCCEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHH
LATASVFEILARTKKRGMNELTLETDSSSLSTPMAMVQMRHLLHPSRSKRK
HHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA