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The map label for this gene is fabF [H]

Identifier: 159184614

GI number: 159184614

Start: 1086634

End: 1087896

Strand: Direct

Name: fabF [H]

Synonym: Atu1097

Alternate gene names: 159184614

Gene position: 1086634-1087896 (Clockwise)

Preceding gene: 159184613

Following gene: 15888438

Centisome position: 38.24

GC content: 61.92

Gene sequence:

>1263_bases
ATGAGGCGTGTCGTTATCACCGGTACCGGCATGGTATCTCCTCTTGGATGCGGAACGGAAGTGACCTGGGAGCGGCTGTT
GGCCGGCCAGAATGGTGCCCGTCTCGTGACTGAATTCGAGGTCGAAGACCTGCCCGCAAAGATCGCCTGCCGCATTCCCG
TCGGCGACGGCTCCAACGGCACCTTCAATGCCGATGACTGGATGGAGCCCAAGGAACAACGCAAGGTCGATCCTTTCATT
CTCTACGGCATGGCTGCCGCCGACATGGCGCTTGCCGACGCAAACTGGCATCCGGAAACGGACGACGACCAGATCGCTAC
CGGCGTTCTGATCGGCTCCGGCATTGGCGGTCTGGAAGGCATTGTCGAGGCGGGTTACACGCTGCGCGACAAGGGCCCAC
GCCGCATTTCTCCATTCTTCATTCCCGGCCGTCTGATCAACCTCGTATCCGGTCAGGTTTCCATTCGCCACAAGCTGCGT
GGACCGAATCATTCCGTGGTAACGGCCTGCTCGACCGGCGCACACGCTATCGGCGACGCCGCCCGACTGATCGCGCTTGG
CGATGCCGAGGTCATGGTCGCCGGTGGTGCCGAATCGCCGGTCTGCCGCATTTCGCTCGCCGGATTTGCCGCCTGCAAGG
CGCTCTCCACCCAGCACAATGACGATCCGCAAAAGGCCTCGCGCCCCTATGATCGCGACCGCGACGGTTTCGTCATGGGC
GAGGGTGCCGGCATCGTTGTTCTCGAAGAACTCGAACACGCCAAGGCGCGCGGCGCGAAGATTTACGCCGAAGTCGTCGG
TTATGGCCTGTCCGGCGATGCCTTCCACATCACGGCGCCGTCCGAGGATGGCGACGGTGCGTATCGCTGCATGTCCATGG
CGCTGAAGCGCGCTGGCCTCACGCCTGACGATATCGACTATATCAACGCCCACGGCACCTCCACCATGGCCGACACGATC
GAGCTTGGCGCGGTCGAACGTCTGGTCGGCGAATCTGCTCCGAAGATTTCCATGTCTTCCACCAAGTCGGCCACCGGCCA
TCTTCTCGGCGCTGCCGGCGCAATCGAGGCGATTTTCGCGACGCTTGCGATCCGCGACAATATCGTTCCGCCGACGCTCA
ACCTCGACAATCCCGATGTCGAGACGAAGATAGACCTCGTGCCGCACAAGGCCCGCAAGCGGCAGGTCAATGTGGCGCTT
TCGAATTCCTTCGGTTTCGGCGGCACCAACGCATCGCTCGTGCTGCGTCGTTACGAAGCATAA

Upstream 100 bases:

>100_bases
ATACAAAGATTAGACATACTGCAGCCTGCTGTGCGTGCTATCCCATGGTGCCCGGTGTTGCAGAAAGACCGATGATTTGG
ATAAGGGCGGAGCATTGGCG

Downstream 100 bases:

>100_bases
TCGCGGCGGCGACACGCCGTCGCTGAAGGTGTCCCGCGCCGCAAGCCGTTCGTGGTTTCTGCGGCGCTCCCTGCGGGCGC
TGACAAAGCATGTTCTTTCC

Product: 3-oxoacyl-(acyl carrier protein) synthase II

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MRRVVITGTGMVSPLGCGTEVTWERLLAGQNGARLVTEFEVEDLPAKIACRIPVGDGSNGTFNADDWMEPKEQRKVDPFI
LYGMAAADMALADANWHPETDDDQIATGVLIGSGIGGLEGIVEAGYTLRDKGPRRISPFFIPGRLINLVSGQVSIRHKLR
GPNHSVVTACSTGAHAIGDAARLIALGDAEVMVAGGAESPVCRISLAGFAACKALSTQHNDDPQKASRPYDRDRDGFVMG
EGAGIVVLEELEHAKARGAKIYAEVVGYGLSGDAFHITAPSEDGDGAYRCMSMALKRAGLTPDDIDYINAHGTSTMADTI
ELGAVERLVGESAPKISMSSTKSATGHLLGAAGAIEAIFATLAIRDNIVPPTLNLDNPDVETKIDLVPHKARKRQVNVAL
SNSFGFGGTNASLVLRRYEA

Sequences:

>Translated_420_residues
MRRVVITGTGMVSPLGCGTEVTWERLLAGQNGARLVTEFEVEDLPAKIACRIPVGDGSNGTFNADDWMEPKEQRKVDPFI
LYGMAAADMALADANWHPETDDDQIATGVLIGSGIGGLEGIVEAGYTLRDKGPRRISPFFIPGRLINLVSGQVSIRHKLR
GPNHSVVTACSTGAHAIGDAARLIALGDAEVMVAGGAESPVCRISLAGFAACKALSTQHNDDPQKASRPYDRDRDGFVMG
EGAGIVVLEELEHAKARGAKIYAEVVGYGLSGDAFHITAPSEDGDGAYRCMSMALKRAGLTPDDIDYINAHGTSTMADTI
ELGAVERLVGESAPKISMSSTKSATGHLLGAAGAIEAIFATLAIRDNIVPPTLNLDNPDVETKIDLVPHKARKRQVNVAL
SNSFGFGGTNASLVLRRYEA
>Mature_420_residues
MRRVVITGTGMVSPLGCGTEVTWERLLAGQNGARLVTEFEVEDLPAKIACRIPVGDGSNGTFNADDWMEPKEQRKVDPFI
LYGMAAADMALADANWHPETDDDQIATGVLIGSGIGGLEGIVEAGYTLRDKGPRRISPFFIPGRLINLVSGQVSIRHKLR
GPNHSVVTACSTGAHAIGDAARLIALGDAEVMVAGGAESPVCRISLAGFAACKALSTQHNDDPQKASRPYDRDRDGFVMG
EGAGIVVLEELEHAKARGAKIYAEVVGYGLSGDAFHITAPSEDGDGAYRCMSMALKRAGLTPDDIDYINAHGTSTMADTI
ELGAVERLVGESAPKISMSSTKSATGHLLGAAGAIEAIFATLAIRDNIVPPTLNLDNPDVETKIDLVPHKARKRQVNVAL
SNSFGFGGTNASLVLRRYEA

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Has a preference for short chain acid substrates and may function to supply the octanoic substrates for lipoic acid biosynthes

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=418, Percent_Identity=51.1961722488038, Blast_Score=426, Evalue=1e-119,
Organism=Homo sapiens, GI223972627, Length=188, Percent_Identity=44.6808510638298, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI41872631, Length=361, Percent_Identity=25.7617728531856, Blast_Score=97, Evalue=3e-20,
Organism=Escherichia coli, GI1787337, Length=418, Percent_Identity=52.3923444976077, Blast_Score=393, Evalue=1e-110,
Organism=Escherichia coli, GI1788663, Length=421, Percent_Identity=38.0047505938242, Blast_Score=263, Evalue=2e-71,
Organism=Caenorhabditis elegans, GI71983541, Length=426, Percent_Identity=38.4976525821596, Blast_Score=266, Evalue=1e-71,
Organism=Caenorhabditis elegans, GI71983535, Length=266, Percent_Identity=43.984962406015, Blast_Score=207, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI212642053, Length=430, Percent_Identity=26.2790697674419, Blast_Score=111, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI17550940, Length=323, Percent_Identity=25.077399380805, Blast_Score=89, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6320904, Length=446, Percent_Identity=40.8071748878924, Blast_Score=298, Evalue=1e-81,
Organism=Drosophila melanogaster, GI24644341, Length=426, Percent_Identity=46.0093896713615, Blast_Score=362, Evalue=1e-100,
Organism=Drosophila melanogaster, GI19920632, Length=361, Percent_Identity=24.6537396121884, Blast_Score=85, Evalue=7e-17,
Organism=Drosophila melanogaster, GI221330659, Length=361, Percent_Identity=24.6537396121884, Blast_Score=85, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24581345, Length=361, Percent_Identity=24.6537396121884, Blast_Score=80, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 44348; Mature: 44348

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: PS00606 B_KETOACYL_SYNTHASE ; PS00107 PROTEIN_KINASE_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRVVITGTGMVSPLGCGTEVTWERLLAGQNGARLVTEFEVEDLPAKIACRIPVGDGSNG
CCEEEEECCCCCCCCCCCCHHHHHHHHCCCCCCEEEEEEECCCCCCEEEEEEECCCCCCC
TFNADDWMEPKEQRKVDPFILYGMAAADMALADANWHPETDDDQIATGVLIGSGIGGLEG
CCCCHHCCCCHHHCCCCCEEEEEHHHHHHEEECCCCCCCCCCCCEEEEEEEECCCCHHHH
IVEAGYTLRDKGPRRISPFFIPGRLINLVSGQVSIRHKLRGPNHSVVTACSTGAHAIGDA
HHHCCCEEECCCCCCCCCEEECHHHHHHHCCCEEEEEECCCCCCCEEEEECCCCHHHCCC
ARLIALGDAEVMVAGGAESPVCRISLAGFAACKALSTQHNDDPQKASRPYDRDRDGFVMG
EEEEEECCCEEEEECCCCCCEEEEEEHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCEEEE
EGAGIVVLEELEHAKARGAKIYAEVVGYGLSGDAFHITAPSEDGDGAYRCMSMALKRAGL
CCCCEEEEECHHHHHHCCCEEEEHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCC
TPDDIDYINAHGTSTMADTIELGAVERLVGESAPKISMSSTKSATGHLLGAAGAIEAIFA
CCCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCEEEHHHHHHHHHH
TLAIRDNIVPPTLNLDNPDVETKIDLVPHKARKRQVNVALSNSFGFGGTNASLVLRRYEA
HHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEEEECCCCCCCCCCEEEEEEECC
>Mature Secondary Structure
MRRVVITGTGMVSPLGCGTEVTWERLLAGQNGARLVTEFEVEDLPAKIACRIPVGDGSNG
CCEEEEECCCCCCCCCCCCHHHHHHHHCCCCCCEEEEEEECCCCCCEEEEEEECCCCCCC
TFNADDWMEPKEQRKVDPFILYGMAAADMALADANWHPETDDDQIATGVLIGSGIGGLEG
CCCCHHCCCCHHHCCCCCEEEEEHHHHHHEEECCCCCCCCCCCCEEEEEEEECCCCHHHH
IVEAGYTLRDKGPRRISPFFIPGRLINLVSGQVSIRHKLRGPNHSVVTACSTGAHAIGDA
HHHCCCEEECCCCCCCCCEEECHHHHHHHCCCEEEEEECCCCCCCEEEEECCCCHHHCCC
ARLIALGDAEVMVAGGAESPVCRISLAGFAACKALSTQHNDDPQKASRPYDRDRDGFVMG
EEEEEECCCEEEEECCCCCCEEEEEEHHHHHHHHHCCCCCCCHHHHCCCCCCCCCCEEEE
EGAGIVVLEELEHAKARGAKIYAEVVGYGLSGDAFHITAPSEDGDGAYRCMSMALKRAGL
CCCCEEEEECHHHHHHCCCEEEEHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCC
TPDDIDYINAHGTSTMADTIELGAVERLVGESAPKISMSSTKSATGHLLGAAGAIEAIFA
CCCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCEEEHHHHHHHHHH
TLAIRDNIVPPTLNLDNPDVETKIDLVPHKARKRQVNVALSNSFGFGGTNASLVLRRYEA
HHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEEEECCCCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10784042; 11481430 [H]