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The map label for this gene is sohB [H]

Identifier: 159184399

GI number: 159184399

Start: 625105

End: 625887

Strand: Direct

Name: sohB [H]

Synonym: Atu0637

Alternate gene names: 159184399

Gene position: 625105-625887 (Clockwise)

Preceding gene: 15887977

Following gene: 15887979

Centisome position: 22.0

GC content: 60.41

Gene sequence:

>783_bases
ATGGCCGGCGGCAACCAGTTCCGCCCCGCCCTCAATCTCGCCTCCTACGCGCCGCTGCTTGAAAAGGCCTTCGCCGTCAA
GGACGCCCCGGCGGTTGCCATCTCGCTGAATTCGCCAGGCGGCTCGCCGGTGCAGGCGCGGATGATCTATAATCGTATCC
GCCAGCTTGCCGAGGAAAAGGACAAGAAGGTTCTGATCTTCGTGGAAGACGTGGCTGCCTCCGGCGGCTACATGATTGCG
CTTGCTGGCGATGAGATCATCGCCGACCCCACCTCCATCGTCGGTTCGATCGGCGTCGTATCCGGCGGCTTCGGTTTTCC
GGAAATGCTGCGGAAGATCGGCGTGGAGCGCCGCGTCTATACCGCTGGCGAAAACAAGGTCATCCTCGATCCGTTCCAGC
CGGAAAAGGAAGGCGATATCGATTACCTGAAGTCCTTGCAGGTCGAAATCCACAATGTCTTCATTGATATGGTCAAGATG
CGCCGGGGCTCGAAGCTGAAGGGCGACGACGCACTCTTTTCCGGCCTGTTCTGGACCGGCATGCGTGGCCTCGACCTCGG
CCTGATTGACGGGCTGGGCGACATGCGCGAGGTTTTGCGCCGCCGTTACGGGACAAAGGTCAAGCTTCAACTCATCAGCG
GCGGGCGTTCGCTGTTCGGCAAAAAAGTGCCTGGCGTGAATATGGCGCTCGGCCTCAATGCTGAAAGGCTCGCGGCAGGC
GCCGTCTCGGGTCTTGCGGAGGTTGCCGAAGAAAAGGCATTGTGGTCGCGTTTCGGTCTATGA

Upstream 100 bases:

>100_bases
ACGCGAGGATTGATTGGTGGGTTTTCTGAAGCATCTGGTGCCGAAACGCTTTCGCAAAAAAGAGCTCGTCATACCCGTCG
TGCGCATGCAGGGCGCGATC

Downstream 100 bases:

>100_bases
TGTCGCAGGAATAAGGCCTTATGGCGCAGCTCATTACAATTCTTCTTCTGCTGGTGGGGTCCATCATCCTCTATCGCCGC
TTTGTTCGCGATGCGGAAAA

Product: proteinase sohB

Products: NA

Alternate protein names: Sodium/proton antiporter nhaA [H]

Number of amino acids: Translated: 260; Mature: 259

Protein sequence:

>260_residues
MAGGNQFRPALNLASYAPLLEKAFAVKDAPAVAISLNSPGGSPVQARMIYNRIRQLAEEKDKKVLIFVEDVAASGGYMIA
LAGDEIIADPTSIVGSIGVVSGGFGFPEMLRKIGVERRVYTAGENKVILDPFQPEKEGDIDYLKSLQVEIHNVFIDMVKM
RRGSKLKGDDALFSGLFWTGMRGLDLGLIDGLGDMREVLRRRYGTKVKLQLISGGRSLFGKKVPGVNMALGLNAERLAAG
AVSGLAEVAEEKALWSRFGL

Sequences:

>Translated_260_residues
MAGGNQFRPALNLASYAPLLEKAFAVKDAPAVAISLNSPGGSPVQARMIYNRIRQLAEEKDKKVLIFVEDVAASGGYMIA
LAGDEIIADPTSIVGSIGVVSGGFGFPEMLRKIGVERRVYTAGENKVILDPFQPEKEGDIDYLKSLQVEIHNVFIDMVKM
RRGSKLKGDDALFSGLFWTGMRGLDLGLIDGLGDMREVLRRRYGTKVKLQLISGGRSLFGKKVPGVNMALGLNAERLAAG
AVSGLAEVAEEKALWSRFGL
>Mature_259_residues
AGGNQFRPALNLASYAPLLEKAFAVKDAPAVAISLNSPGGSPVQARMIYNRIRQLAEEKDKKVLIFVEDVAASGGYMIAL
AGDEIIADPTSIVGSIGVVSGGFGFPEMLRKIGVERRVYTAGENKVILDPFQPEKEGDIDYLKSLQVEIHNVFIDMVKMR
RGSKLKGDDALFSGLFWTGMRGLDLGLIDGLGDMREVLRRRYGTKVKLQLISGGRSLFGKKVPGVNMALGLNAERLAAGA
VSGLAEVAEEKALWSRFGL

Specific function: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons [H]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1787527, Length=176, Percent_Identity=32.3863636363636, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788064, Length=176, Percent_Identity=31.25, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023171
- InterPro:   IPR004670
- InterPro:   IPR002142 [H]

Pfam domain/function: PF06965 Na_H_antiport_1; PF01343 Peptidase_S49 [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 28029; Mature: 27898

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGGNQFRPALNLASYAPLLEKAFAVKDAPAVAISLNSPGGSPVQARMIYNRIRQLAEEK
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHC
DKKVLIFVEDVAASGGYMIALAGDEIIADPTSIVGSIGVVSGGFGFPEMLRKIGVERRVY
CCEEEEEEEEECCCCCEEEEEECCCEECCHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEE
TAGENKVILDPFQPEKEGDIDYLKSLQVEIHNVFIDMVKMRRGSKLKGDDALFSGLFWTG
ECCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHC
MRGLDLGLIDGLGDMREVLRRRYGTKVKLQLISGGRSLFGKKVPGVNMALGLNAERLAAG
CCCCCHHHHCCCHHHHHHHHHHCCCEEEEEEECCCHHHHCCCCCCCEEEECCCHHHHHHH
AVSGLAEVAEEKALWSRFGL
HHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AGGNQFRPALNLASYAPLLEKAFAVKDAPAVAISLNSPGGSPVQARMIYNRIRQLAEEK
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHC
DKKVLIFVEDVAASGGYMIALAGDEIIADPTSIVGSIGVVSGGFGFPEMLRKIGVERRVY
CCEEEEEEEEECCCCCEEEEEECCCEECCHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEE
TAGENKVILDPFQPEKEGDIDYLKSLQVEIHNVFIDMVKMRRGSKLKGDDALFSGLFWTG
ECCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHC
MRGLDLGLIDGLGDMREVLRRRYGTKVKLQLISGGRSLFGKKVPGVNMALGLNAERLAAG
CCCCCHHHHCCCHHHHHHHHHHCCCEEEEEEECCCHHHHCCCCCCCEEEECCCHHHHHHH
AVSGLAEVAEEKALWSRFGL
HHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA