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The map label for this gene is cat1 [H]

Identifier: 159184290

GI number: 159184290

Start: 389381

End: 390877

Strand: Direct

Name: cat1 [H]

Synonym: Atu0396

Alternate gene names: 159184290

Gene position: 389381-390877 (Clockwise)

Preceding gene: 159184289

Following gene: 159184291

Centisome position: 13.7

GC content: 59.32

Gene sequence:

>1497_bases
ATGCTTGAAAAGCGTATCCGCAACGCGTCCCTCTTGAACAGGATCGTCAGCGCCGAAGAGGCCGCCAGTCTCATTCAGGA
TGGCATGACGGTGGGCATGAGCGGTTTTACGCGCGCCGGTGAAGCCAAGGCAGTGCCGCTGGCGCTGGCCGAGCGCGCCA
AGACCAACCCCATGAAAATCACCCTGATGACCGGCGCCTCCCTCGGCAACGATCTCGACAAGACCATGGTCGAGGCCGGC
ATGCTGGCGCGCCGCATGCCGTTCCAGTCCGATCCGGCTTTGCGCAAGGCGATCAATGACGGCAGGGTGATGTTCATCGA
TCAGCATCTTTCCGAAACGGTCGAGCAATTGCGCGGCGGTCAGATCCATGGCGTTGATATCGCCATTGTCGAGGCGGTGG
CAATCACGGCGGAAGGCGGCATCGTACCCACCACCTCGGTTGGTAATTCCGCAAGTTTCGCCATTCTGGCCGATAAGGTC
ATCGTCGAGATCAACCTGTCGCAGCCCGAGGTGCTGGAAGGGCTGCATGATATCTTCATTCCCGCCAAGCGCCCGACCCG
TATGCCCATCCCCGTCGTGGCGACGGATAGCCGTGTCGGCCTGCCTTTCATTCCGGTGCCGCCGGAAAAGATCGCTGCCA
TTGTGCTGAGCGACAAGAGCGACAGTTTTTCGACAGTGCTGCCGCCGGATGACGAGACGAAGGCGATTGCCGGCCATCTC
ACCGAATTCCTGCTGAATGAGGTCCGTCATGGCCGCATGACGCATGAACTCCAGCCGTTGCAGGCAGGCATCGGCACCAT
CGCCAATGCCGTGATGCACGGGTTCATCGATACGCCGTTTCACGATCTCAAAATGTATTCGGAGGTCCTGCAGGATTCGA
CCTTCGAACTGTTCGATGCGGGCAAGCTGACCTTCGCCTCCGGTTCGTCAATCACGCTCTCCTCCGCCATGAACGAGCAG
GTCATGCCACGATTGTCCGAGTATAAGAGCAGACTGATCCTTCGCCCGCAGGAGGTCAGCAACCATCCGGAAGTCATCCG
CCGCCTCGGCATCATCGGCATCAACACAGCTCTGGAATTCGATATTTACGGAAATGTCAATTCCACTCATGTCGGTGGCA
CTCACATGATGAACGGCATCGGCGGTTCGGGTGATTTTGCCCGCAACGCTTACATGTCCATCTTCGTGACGAAATCCATC
GCCAAGGGCGGTGCCATTTCCAGCGTCGTGCCCATGGTCAGCCATGTCGACCATACCGAACACGATGTCGATATTCTCGT
CACAGAAACGGGCCTAGCCGATCTGCGCGGTCTGGCCCCGCGCGAGCGCGCAGCGGTCATCATCGCAAACTGCGTGCATC
CCAGCTATCGCGATGCGCTGACGGATTATTACCAGCGAGCAGCGGCGCGGGGCGGGCACACGCCGCATCTCATCGAAGAA
GCGCTGTCATGGCACAATGCGCTTCGGGAAAGAGGCACCATGCTGCCGCAGCGATAG

Upstream 100 bases:

>100_bases
GATCTATGTCAGTTTCATCGATCAAACTGCACGCCATAGTCGCCCGAGAGGTGGCCAACCGAATGCCGTGCCATCGTGAT
GACAGATCATGGAGAAGTGC

Downstream 100 bases:

>100_bases
GCGGGCGTTTTCCGGCCTGTCGCCCGGCAATTGGGTCCGTTCGGACACACCGGGGCGGAAAGTGTCGCTGATCCGCGTTG
GTTGCTGGCGCGGCAGTTCC

Product: coenzyme A transferase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 498; Mature: 498

Protein sequence:

>498_residues
MLEKRIRNASLLNRIVSAEEAASLIQDGMTVGMSGFTRAGEAKAVPLALAERAKTNPMKITLMTGASLGNDLDKTMVEAG
MLARRMPFQSDPALRKAINDGRVMFIDQHLSETVEQLRGGQIHGVDIAIVEAVAITAEGGIVPTTSVGNSASFAILADKV
IVEINLSQPEVLEGLHDIFIPAKRPTRMPIPVVATDSRVGLPFIPVPPEKIAAIVLSDKSDSFSTVLPPDDETKAIAGHL
TEFLLNEVRHGRMTHELQPLQAGIGTIANAVMHGFIDTPFHDLKMYSEVLQDSTFELFDAGKLTFASGSSITLSSAMNEQ
VMPRLSEYKSRLILRPQEVSNHPEVIRRLGIIGINTALEFDIYGNVNSTHVGGTHMMNGIGGSGDFARNAYMSIFVTKSI
AKGGAISSVVPMVSHVDHTEHDVDILVTETGLADLRGLAPRERAAVIIANCVHPSYRDALTDYYQRAAARGGHTPHLIEE
ALSWHNALRERGTMLPQR

Sequences:

>Translated_498_residues
MLEKRIRNASLLNRIVSAEEAASLIQDGMTVGMSGFTRAGEAKAVPLALAERAKTNPMKITLMTGASLGNDLDKTMVEAG
MLARRMPFQSDPALRKAINDGRVMFIDQHLSETVEQLRGGQIHGVDIAIVEAVAITAEGGIVPTTSVGNSASFAILADKV
IVEINLSQPEVLEGLHDIFIPAKRPTRMPIPVVATDSRVGLPFIPVPPEKIAAIVLSDKSDSFSTVLPPDDETKAIAGHL
TEFLLNEVRHGRMTHELQPLQAGIGTIANAVMHGFIDTPFHDLKMYSEVLQDSTFELFDAGKLTFASGSSITLSSAMNEQ
VMPRLSEYKSRLILRPQEVSNHPEVIRRLGIIGINTALEFDIYGNVNSTHVGGTHMMNGIGGSGDFARNAYMSIFVTKSI
AKGGAISSVVPMVSHVDHTEHDVDILVTETGLADLRGLAPRERAAVIIANCVHPSYRDALTDYYQRAAARGGHTPHLIEE
ALSWHNALRERGTMLPQR
>Mature_498_residues
MLEKRIRNASLLNRIVSAEEAASLIQDGMTVGMSGFTRAGEAKAVPLALAERAKTNPMKITLMTGASLGNDLDKTMVEAG
MLARRMPFQSDPALRKAINDGRVMFIDQHLSETVEQLRGGQIHGVDIAIVEAVAITAEGGIVPTTSVGNSASFAILADKV
IVEINLSQPEVLEGLHDIFIPAKRPTRMPIPVVATDSRVGLPFIPVPPEKIAAIVLSDKSDSFSTVLPPDDETKAIAGHL
TEFLLNEVRHGRMTHELQPLQAGIGTIANAVMHGFIDTPFHDLKMYSEVLQDSTFELFDAGKLTFASGSSITLSSAMNEQ
VMPRLSEYKSRLILRPQEVSNHPEVIRRLGIIGINTALEFDIYGNVNSTHVGGTHMMNGIGGSGDFARNAYMSIFVTKSI
AKGGAISSVVPMVSHVDHTEHDVDILVTETGLADLRGLAPRERAAVIIANCVHPSYRDALTDYYQRAAARGGHTPHLIEE
ALSWHNALRERGTMLPQR

Specific function: Forms succinyl-CoA from succinate and acetyl-CoA [H]

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=487, Percent_Identity=44.7638603696099, Blast_Score=412, Evalue=1e-116,
Organism=Saccharomyces cerevisiae, GI6319456, Length=514, Percent_Identity=44.5525291828794, Blast_Score=426, Evalue=1e-120,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702
- InterPro:   IPR006472
- InterPro:   IPR017821 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro; PF04223 CitF [H]

EC number: NA

Molecular weight: Translated: 53895; Mature: 53895

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEKRIRNASLLNRIVSAEEAASLIQDGMTVGMSGFTRAGEAKAVPLALAERAKTNPMKI
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCEEE
TLMTGASLGNDLDKTMVEAGMLARRMPFQSDPALRKAINDGRVMFIDQHLSETVEQLRGG
EEEECCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCEEEEHHHHHHHHHHHCCC
QIHGVDIAIVEAVAITAEGGIVPTTSVGNSASFAILADKVIVEINLSQPEVLEGLHDIFI
CCCCEEEEEEEEEEEEECCCEEECCCCCCCCEEEEEEEEEEEEEECCCCHHHHHHHHHCC
PAKRPTRMPIPVVATDSRVGLPFIPVPPEKIAAIVLSDKSDSFSTVLPPDDETKAIAGHL
CCCCCCCCCCEEEECCCCCCCCCCCCCHHHEEEEEEECCCCCCCCCCCCCCCHHHHHHHH
TEFLLNEVRHGRMTHELQPLQAGIGTIANAVMHGFIDTPFHDLKMYSEVLQDSTFELFDA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHCC
GKLTFASGSSITLSSAMNEQVMPRLSEYKSRLILRPQEVSNHPEVIRRLGIIGINTALEF
CCEEEECCCCEEEHHHHCHHHHHHHHHHHHHEEECCHHHCCCHHHHHHHCCEEECCEEEE
DIYGNVNSTHVGGTHMMNGIGGSGDFARNAYMSIFVTKSIAKGGAISSVVPMVSHVDHTE
EEECCCCCCCCCCHHHHCCCCCCCCHHHHHHEEEEEEHHHHCCCCHHHHHHHHHHCCCCC
HDVDILVTETGLADLRGLAPRERAAVIIANCVHPSYRDALTDYYQRAAARGGHTPHLIEE
CCEEEEEECCCHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHH
ALSWHNALRERGTMLPQR
HHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLEKRIRNASLLNRIVSAEEAASLIQDGMTVGMSGFTRAGEAKAVPLALAERAKTNPMKI
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCEEE
TLMTGASLGNDLDKTMVEAGMLARRMPFQSDPALRKAINDGRVMFIDQHLSETVEQLRGG
EEEECCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCEEEEHHHHHHHHHHHCCC
QIHGVDIAIVEAVAITAEGGIVPTTSVGNSASFAILADKVIVEINLSQPEVLEGLHDIFI
CCCCEEEEEEEEEEEEECCCEEECCCCCCCCEEEEEEEEEEEEEECCCCHHHHHHHHHCC
PAKRPTRMPIPVVATDSRVGLPFIPVPPEKIAAIVLSDKSDSFSTVLPPDDETKAIAGHL
CCCCCCCCCCEEEECCCCCCCCCCCCCHHHEEEEEEECCCCCCCCCCCCCCCHHHHHHHH
TEFLLNEVRHGRMTHELQPLQAGIGTIANAVMHGFIDTPFHDLKMYSEVLQDSTFELFDA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHCC
GKLTFASGSSITLSSAMNEQVMPRLSEYKSRLILRPQEVSNHPEVIRRLGIIGINTALEF
CCEEEECCCCEEEHHHHCHHHHHHHHHHHHHEEECCHHHCCCHHHHHHHCCEEECCEEEE
DIYGNVNSTHVGGTHMMNGIGGSGDFARNAYMSIFVTKSIAKGGAISSVVPMVSHVDHTE
EEECCCCCCCCCCHHHHCCCCCCCCHHHHHHEEEEEEHHHHCCCCHHHHHHHHHHCCCCC
HDVDILVTETGLADLRGLAPRERAAVIIANCVHPSYRDALTDYYQRAAARGGHTPHLIEE
CCEEEEEECCCHHHHHCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCHHHHHH
ALSWHNALRERGTMLPQR
HHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]