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The map label for this gene is cyaA [H]

Identifier: 15889837

GI number: 15889837

Start: 2554576

End: 2556270

Strand: Direct

Name: cyaA [H]

Synonym: Atu2580

Alternate gene names: 15889837

Gene position: 2554576-2556270 (Clockwise)

Preceding gene: 159185275

Following gene: 159185277

Centisome position: 89.9

GC content: 57.58

Gene sequence:

>1695_bases
ATGATCCGTTTCTTTTCGGAAACCAATTTAAGACGCGCCCGGATCGCATCCGGTCTCATCCTATTTGCTTTCGTTTTTTC
CCACCTCTCCAATCATTCCCTTGCACTCATCTCCATCGACACGGCTGAACGGGCGCGGAAATGGTTCAGCTTGATTTGGC
TTAATCCTGTCAGCAGCCTGCTTTTTTACGGGTCGGTCGTGGTGCATGTCTGCCTTGTACTGCGCTCGCTTTATCTGCGC
AGGACATTGCGCATGCCGCTGCGCGAGGCGCTTCAGGTCATATTCGGACTGTCGATCCCGTTTCTGATCATCGGCCATGC
GGTCAATATCCGCGCCTCACATATGCTTTATGGCATCGACGTCGGTTATTATTCCGTCATCCGGAGGCTGTGGATAAACA
ATCCGGTCAGCGGAGCGTGGCAGAGCCTCGCGTTGATTGTCATCTGGACCCATGGATGCATCGGCCTCTATTTCTGGCTG
CGTTATCGCGACTGGTATCCAAAAATCGCCGGGCTGTTCATGACGGTGGCTGTGATGCTGCCGCTTCTGGCCTTGCTGGG
CTTCAGCGATGCGGGCCGCTGGCTGGAAGAGGTAGATCGGAAATATGCACTTCCTCCGGGGCTTACGGATAACACTATCC
AGAGAGACGAACTGCCGCTGCAAAGGGAGATGGAAACGCGGATCCGGTTCATCACAGGTGCGACCGAGGCAATTTTCGCC
GGCGCGGTGATGCTGGTCTTCGTTTTGCGTGGTGTGCGAAGCTTCCGGCAAAGGCTGACCGCGATTGAAATCCACTATGA
ACAGGGCGTGCAGGCGCGTATTCCGGCCGGCTTCAGTATTCTGGAAGCCAGCAGGCTCGCGGGCATCCCGCATTACTCGG
TCTGTGGCGGCAAGGGGCGCTGCTCGACCTGTCGCGTCAAGGTTCTGAACAGCAAGGGCCCGCTTCCGCCACCCGGAGAT
ATCGAGCAGACCACGCTCCGGCGTATCCACGCCGATTCGGACGTGCGGCTCGGTTGTCAGTTGCGCCCCACCAGCGATCT
CGACATCGCGCTTCTCGTTTCACCGCCCCAGCAAAGCGATCTGCCCGCGGATGCGCAGTCGGCCCGCCCCGGTCGGGAAG
AGGAAATCGCCATTCTCTTCTGCGATCTGCGCAATTTCACCACGCTGTCGGAAGCGAAGCTGCCCTATGATGTGGTCTTC
CTTTTGAACCGCTACTTCACCATCGTCGGCCAGGCCGTCGAACAGGCCGATGGTCATCTCGACAAATTCATCGGCGATGG
CGCCATGGCCCTTTTTGGACTTGGCGAGGATACGGACCGGGCCTGCCGCAACGCCATGAAGGCAGCCGCAACCATATTGC
GGGATATCGCCATCCTGAACGAAGGGTTGGAGAAACAATTCGCCGTCCGCCTGGAAGTGGTGGTTGGCATTCACTCCGGC
CCGAGCATCGTCGGCGTGATGGGATATGGCGCGGCAAAAACCCTGACAGCCATAGGCGATACCGTGAATGTGGCAAGCCG
GCTCGAATCCAAGGCCAAGGAATTCGGCGCCGCCATCGTCGTTTCCGAACCGGCCATCATCCAGGCAGGACAGGATATTG
CCGATCTCAGAAGCGAAAACATCGCCATTCGCGGACGAAACTCGCAGATGAAAGTGTATCTGCTCTCAAGAGAAGAGAGC
GAGCGTTATCTATGA

Upstream 100 bases:

>100_bases
TATCCCGTTTTCCGCGTGGAAATTCGGCGAGACGACCTAAGATTAAGCCACCCGTATTGCATGATGATTCTATTCCGAAC
GGCCATTTGATGGGATTTGC

Downstream 100 bases:

>100_bases
GACAGTCACGGCGCTTTTGTCGTCGGGCGGTCCACCGTCAAATCTTGCGATAGAGAAAATAGCGATCCGTCGGCACGCTT
TCCGGCACCGGCAGCGGTTT

Product: adenylate cyclase

Products: NA

Alternate protein names: ATP pyrophosphate-lyase; Adenylyl cyclase [H]

Number of amino acids: Translated: 564; Mature: 564

Protein sequence:

>564_residues
MIRFFSETNLRRARIASGLILFAFVFSHLSNHSLALISIDTAERARKWFSLIWLNPVSSLLFYGSVVVHVCLVLRSLYLR
RTLRMPLREALQVIFGLSIPFLIIGHAVNIRASHMLYGIDVGYYSVIRRLWINNPVSGAWQSLALIVIWTHGCIGLYFWL
RYRDWYPKIAGLFMTVAVMLPLLALLGFSDAGRWLEEVDRKYALPPGLTDNTIQRDELPLQREMETRIRFITGATEAIFA
GAVMLVFVLRGVRSFRQRLTAIEIHYEQGVQARIPAGFSILEASRLAGIPHYSVCGGKGRCSTCRVKVLNSKGPLPPPGD
IEQTTLRRIHADSDVRLGCQLRPTSDLDIALLVSPPQQSDLPADAQSARPGREEEIAILFCDLRNFTTLSEAKLPYDVVF
LLNRYFTIVGQAVEQADGHLDKFIGDGAMALFGLGEDTDRACRNAMKAAATILRDIAILNEGLEKQFAVRLEVVVGIHSG
PSIVGVMGYGAAKTLTAIGDTVNVASRLESKAKEFGAAIVVSEPAIIQAGQDIADLRSENIAIRGRNSQMKVYLLSREES
ERYL

Sequences:

>Translated_564_residues
MIRFFSETNLRRARIASGLILFAFVFSHLSNHSLALISIDTAERARKWFSLIWLNPVSSLLFYGSVVVHVCLVLRSLYLR
RTLRMPLREALQVIFGLSIPFLIIGHAVNIRASHMLYGIDVGYYSVIRRLWINNPVSGAWQSLALIVIWTHGCIGLYFWL
RYRDWYPKIAGLFMTVAVMLPLLALLGFSDAGRWLEEVDRKYALPPGLTDNTIQRDELPLQREMETRIRFITGATEAIFA
GAVMLVFVLRGVRSFRQRLTAIEIHYEQGVQARIPAGFSILEASRLAGIPHYSVCGGKGRCSTCRVKVLNSKGPLPPPGD
IEQTTLRRIHADSDVRLGCQLRPTSDLDIALLVSPPQQSDLPADAQSARPGREEEIAILFCDLRNFTTLSEAKLPYDVVF
LLNRYFTIVGQAVEQADGHLDKFIGDGAMALFGLGEDTDRACRNAMKAAATILRDIAILNEGLEKQFAVRLEVVVGIHSG
PSIVGVMGYGAAKTLTAIGDTVNVASRLESKAKEFGAAIVVSEPAIIQAGQDIADLRSENIAIRGRNSQMKVYLLSREES
ERYL
>Mature_564_residues
MIRFFSETNLRRARIASGLILFAFVFSHLSNHSLALISIDTAERARKWFSLIWLNPVSSLLFYGSVVVHVCLVLRSLYLR
RTLRMPLREALQVIFGLSIPFLIIGHAVNIRASHMLYGIDVGYYSVIRRLWINNPVSGAWQSLALIVIWTHGCIGLYFWL
RYRDWYPKIAGLFMTVAVMLPLLALLGFSDAGRWLEEVDRKYALPPGLTDNTIQRDELPLQREMETRIRFITGATEAIFA
GAVMLVFVLRGVRSFRQRLTAIEIHYEQGVQARIPAGFSILEASRLAGIPHYSVCGGKGRCSTCRVKVLNSKGPLPPPGD
IEQTTLRRIHADSDVRLGCQLRPTSDLDIALLVSPPQQSDLPADAQSARPGREEEIAILFCDLRNFTTLSEAKLPYDVVF
LLNRYFTIVGQAVEQADGHLDKFIGDGAMALFGLGEDTDRACRNAMKAAATILRDIAILNEGLEKQFAVRLEVVVGIHSG
PSIVGVMGYGAAKTLTAIGDTVNVASRLESKAKEFGAAIVVSEPAIIQAGQDIADLRSENIAIRGRNSQMKVYLLSREES
ERYL

Specific function: May function as a membrane-localized receptor protein [H]

COG id: COG0633

COG function: function code C; Ferredoxin

Gene ontology:

Cell location: Cellular thylakoid membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HAMP domain [H]

Homologues:

Organism=Homo sapiens, GI4504217, Length=211, Percent_Identity=28.436018957346, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI222080083, Length=196, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=6e-12,
Organism=Homo sapiens, GI134152694, Length=208, Percent_Identity=25.9615384615385, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI167830411, Length=192, Percent_Identity=29.6875, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI4580422, Length=189, Percent_Identity=29.1005291005291, Blast_Score=68, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17561804, Length=212, Percent_Identity=27.8301886792453, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI193207841, Length=232, Percent_Identity=28.8793103448276, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17534655, Length=177, Percent_Identity=31.638418079096, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17561800, Length=210, Percent_Identity=29.0476190476191, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17561802, Length=198, Percent_Identity=29.2929292929293, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI193206632, Length=169, Percent_Identity=29.585798816568, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI212645052, Length=202, Percent_Identity=31.1881188118812, Blast_Score=70, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17534657, Length=177, Percent_Identity=29.9435028248588, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17534659, Length=182, Percent_Identity=27.4725274725275, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71990146, Length=210, Percent_Identity=29.0476190476191, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17561794, Length=160, Percent_Identity=29.375, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI221330468, Length=267, Percent_Identity=25.0936329588015, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI221330470, Length=267, Percent_Identity=25.0936329588015, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI161076872, Length=187, Percent_Identity=26.7379679144385, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28574512, Length=187, Percent_Identity=26.7379679144385, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI116008008, Length=185, Percent_Identity=25.4054054054054, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI62484298, Length=185, Percent_Identity=25.4054054054054, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI62484477, Length=185, Percent_Identity=25.4054054054054, Blast_Score=69, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00211 Guanylate_cyc; PF00672 HAMP [H]

EC number: =4.6.1.1 [H]

Molecular weight: Translated: 62687; Mature: 62687

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: PS50125 GUANYLATE_CYCLASES_2 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRFFSETNLRRARIASGLILFAFVFSHLSNHSLALISIDTAERARKWFSLIWLNPVSSL
CEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHH
LFYGSVVVHVCLVLRSLYLRRTLRMPLREALQVIFGLSIPFLIIGHAVNIRASHMLYGID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCEEEEECEEEEEEC
VGYYSVIRRLWINNPVSGAWQSLALIVIWTHGCIGLYFWLRYRDWYPKIAGLFMTVAVML
HHHHHHHHHHHCCCCCCHHHHHHEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PLLALLGFSDAGRWLEEVDRKYALPPGLTDNTIQRDELPLQREMETRIRFITGATEAIFA
HHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHH
GAVMLVFVLRGVRSFRQRLTAIEIHYEQGVQARIPAGFSILEASRLAGIPHYSVCGGKGR
HHHHHHHHHHHHHHHHHHHHEEEEEECCCCCEECCCCHHHHHHHHHCCCCCCEECCCCCC
CSTCRVKVLNSKGPLPPPGDIEQTTLRRIHADSDVRLGCQLRPTSDLDIALLVSPPQQSD
CCEEEEEEECCCCCCCCCCCCHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEECCCCCCC
LPADAQSARPGREEEIAILFCDLRNFTTLSEAKLPYDVVFLLNRYFTIVGQAVEQADGHL
CCCCCCCCCCCCCCCEEEEEEECCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHH
DKFIGDGAMALFGLGEDTDRACRNAMKAAATILRDIAILNEGLEKQFAVRLEVVVGIHSG
HHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHEEEEEEEEECCC
PSIVGVMGYGAAKTLTAIGDTVNVASRLESKAKEFGAAIVVSEPAIIQAGQDIADLRSEN
CCEEEEECCCHHHHHHHHCCHHHHHHHHHHHHHHHCCEEEEECCHHEECCCCHHHHCCCC
IAIRGRNSQMKVYLLSREESERYL
EEEEECCCCEEEEEEECCCCCCCC
>Mature Secondary Structure
MIRFFSETNLRRARIASGLILFAFVFSHLSNHSLALISIDTAERARKWFSLIWLNPVSSL
CEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHH
LFYGSVVVHVCLVLRSLYLRRTLRMPLREALQVIFGLSIPFLIIGHAVNIRASHMLYGID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCEEEEECEEEEEEC
VGYYSVIRRLWINNPVSGAWQSLALIVIWTHGCIGLYFWLRYRDWYPKIAGLFMTVAVML
HHHHHHHHHHHCCCCCCHHHHHHEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PLLALLGFSDAGRWLEEVDRKYALPPGLTDNTIQRDELPLQREMETRIRFITGATEAIFA
HHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHH
GAVMLVFVLRGVRSFRQRLTAIEIHYEQGVQARIPAGFSILEASRLAGIPHYSVCGGKGR
HHHHHHHHHHHHHHHHHHHHEEEEEECCCCCEECCCCHHHHHHHHHCCCCCCEECCCCCC
CSTCRVKVLNSKGPLPPPGDIEQTTLRRIHADSDVRLGCQLRPTSDLDIALLVSPPQQSD
CCEEEEEEECCCCCCCCCCCCHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEECCCCCCC
LPADAQSARPGREEEIAILFCDLRNFTTLSEAKLPYDVVFLLNRYFTIVGQAVEQADGHL
CCCCCCCCCCCCCCCEEEEEEECCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHH
DKFIGDGAMALFGLGEDTDRACRNAMKAAATILRDIAILNEGLEKQFAVRLEVVVGIHSG
HHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHEEEEEEEEECCC
PSIVGVMGYGAAKTLTAIGDTVNVASRLESKAKEFGAAIVVSEPAIIQAGQDIADLRSEN
CCEEEEECCCHHHHHHHHCCHHHHHHHHHHHHHHHCCEEEEECCHHEECCCCHHHHCCCC
IAIRGRNSQMKVYLLSREESERYL
EEEEECCCCEEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7601856 [H]