Click here to switch to the map view.

The map label for this gene is ctrA [H]

Identifier: 15889704

GI number: 15889704

Start: 2405136

End: 2405840

Strand: Direct

Name: ctrA [H]

Synonym: Atu2434

Alternate gene names: 15889704

Gene position: 2405136-2405840 (Clockwise)

Preceding gene: 15889703

Following gene: 15889705

Centisome position: 84.64

GC content: 58.16

Gene sequence:

>705_bases
ATGCGGGTTCTACTGATTGAAGACGACAGCGCAACAGCGCAGAGCATTGAACTGATGCTCAAGTCGGAGAGCTTTAACGT
CTACACGACCGACCTCGGTGAGGAAGGCGTCGACCTTGGCAAGCTTTACGACTACGACATTATTCTTCTCGACCTCAACC
TGCCCGACATGTCGGGTTACGAGGTGCTGAGAACGCTTCGCCTCTCCAAGGTCAAGACGCCGATCCTCATCCTGTCCGGC
ATGGCCGGCATCGAGGACAAGGTGCGCGGCCTCGGCTTCGGCGCAGACGATTACATGACGAAGCCGTTCCACAAGGATGA
GCTTGTTGCCCGTATTCACGCCATCGTCCGCCGTTCCAAGGGCCATGCGCAGTCGGTCATCTCCACCGGTGAGCTGATCG
TCAATCTCGATGCCAAGACGGTTGAAGTGGGCGGCCAGCGCGTTCACCTGACCGGCAAGGAATATCAGATGCTCGAGCTG
CTTTCGCTGCGCAAGGGCACGACGCTGACCAAGGAAATGTTCCTGAACCACCTTTATGGCGGCATGGACGAGCCGGAACT
GAAGATCATCGACGTCTTCATCTGCAAGCTGCGCAAGAAGCTGGCAAATGCCGCCGGCGGCGCAAATTACATCGAAACCG
TCTGGGGCCGCGGCTATGTTCTGCGCGAGCCTGACGGCGCTGCGGAATTCCTCGAAACCGCCTGA

Upstream 100 bases:

>100_bases
TTGTTAACCATTTGGTGGCAGCCTGCAAATCAGGCAACGTCTGGATCCGCATCGCGCGAGGCAATGATTTACCGGTTCGC
GGGCGGCAAAGGGGATAATT

Downstream 100 bases:

>100_bases
TCCAATAGGGTACAGGACAGTTTTTAAAAGACCCGCTGGCGACAGCGGGTTTTTTGTTGCTCTTTCCTATACCTGTCACA
GGAATGAGCAAGAGAAAGAC

Product: two component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MRVLLIEDDSATAQSIELMLKSESFNVYTTDLGEEGVDLGKLYDYDIILLDLNLPDMSGYEVLRTLRLSKVKTPILILSG
MAGIEDKVRGLGFGADDYMTKPFHKDELVARIHAIVRRSKGHAQSVISTGELIVNLDAKTVEVGGQRVHLTGKEYQMLEL
LSLRKGTTLTKEMFLNHLYGGMDEPELKIIDVFICKLRKKLANAAGGANYIETVWGRGYVLREPDGAAEFLETA

Sequences:

>Translated_234_residues
MRVLLIEDDSATAQSIELMLKSESFNVYTTDLGEEGVDLGKLYDYDIILLDLNLPDMSGYEVLRTLRLSKVKTPILILSG
MAGIEDKVRGLGFGADDYMTKPFHKDELVARIHAIVRRSKGHAQSVISTGELIVNLDAKTVEVGGQRVHLTGKEYQMLEL
LSLRKGTTLTKEMFLNHLYGGMDEPELKIIDVFICKLRKKLANAAGGANYIETVWGRGYVLREPDGAAEFLETA
>Mature_234_residues
MRVLLIEDDSATAQSIELMLKSESFNVYTTDLGEEGVDLGKLYDYDIILLDLNLPDMSGYEVLRTLRLSKVKTPILILSG
MAGIEDKVRGLGFGADDYMTKPFHKDELVARIHAIVRRSKGHAQSVISTGELIVNLDAKTVEVGGQRVHLTGKEYQMLEL
LSLRKGTTLTKEMFLNHLYGGMDEPELKIIDVFICKLRKKLANAAGGANYIETVWGRGYVLREPDGAAEFLETA

Specific function: Essential protein that plays a role in the control of cell division, possibly through the transcriptional regulation of ccrM, rpoD, pleC, minC and ftsZ genes [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790552, Length=224, Percent_Identity=36.1607142857143, Blast_Score=140, Evalue=5e-35,
Organism=Escherichia coli, GI1786784, Length=227, Percent_Identity=35.2422907488987, Blast_Score=140, Evalue=9e-35,
Organism=Escherichia coli, GI1789402, Length=223, Percent_Identity=34.5291479820628, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI1787375, Length=221, Percent_Identity=33.9366515837104, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=33.1818181818182, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=32.4561403508772, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1789809, Length=233, Percent_Identity=30.0429184549356, Blast_Score=110, Evalue=6e-26,
Organism=Escherichia coli, GI1786599, Length=221, Percent_Identity=31.6742081447964, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI1786911, Length=219, Percent_Identity=30.1369863013699, Blast_Score=107, Evalue=6e-25,
Organism=Escherichia coli, GI1790860, Length=222, Percent_Identity=30.1801801801802, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1788394, Length=221, Percent_Identity=31.2217194570136, Blast_Score=104, Evalue=4e-24,
Organism=Escherichia coli, GI1787229, Length=227, Percent_Identity=30.8370044052863, Blast_Score=103, Evalue=9e-24,
Organism=Escherichia coli, GI1790863, Length=227, Percent_Identity=25.9911894273128, Blast_Score=87, Evalue=8e-19,
Organism=Escherichia coli, GI1788550, Length=118, Percent_Identity=27.9661016949153, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790437, Length=160, Percent_Identity=25, Blast_Score=67, Evalue=7e-13,
Organism=Escherichia coli, GI145693140, Length=235, Percent_Identity=25.1063829787234, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1789149, Length=145, Percent_Identity=27.5862068965517, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26009; Mature: 26009

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLLIEDDSATAQSIELMLKSESFNVYTTDLGEEGVDLGKLYDYDIILLDLNLPDMSGY
CEEEEEECCCCHHHHHEEEEECCCCEEEECCCCCCCCCCCEEECEEEEEEEECCCCCCHH
EVLRTLRLSKVKTPILILSGMAGIEDKVRGLGFGADDYMTKPFHKDELVARIHAIVRRSK
HHHHHHHHHHCCCCEEEEECCCCCHHHHHHCCCCCHHCCCCCCCHHHHHHHHHHHHHCCC
GHAQSVISTGELIVNLDAKTVEVGGQRVHLTGKEYQMLELLSLRKGTTLTKEMFLNHLYG
CHHHHHHCCCCEEEEECCEEEEECCCEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHC
GMDEPELKIIDVFICKLRKKLANAAGGANYIETVWGRGYVLREPDGAAEFLETA
CCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCEEEECCCCHHHHHHCC
>Mature Secondary Structure
MRVLLIEDDSATAQSIELMLKSESFNVYTTDLGEEGVDLGKLYDYDIILLDLNLPDMSGY
CEEEEEECCCCHHHHHEEEEECCCCEEEECCCCCCCCCCCEEECEEEEEEEECCCCCCHH
EVLRTLRLSKVKTPILILSGMAGIEDKVRGLGFGADDYMTKPFHKDELVARIHAIVRRSK
HHHHHHHHHHCCCCEEEEECCCCCHHHHHHCCCCCHHCCCCCCCHHHHHHHHHHHHHCCC
GHAQSVISTGELIVNLDAKTVEVGGQRVHLTGKEYQMLELLSLRKGTTLTKEMFLNHLYG
CHHHHHHCCCCEEEEECCEEEEECCCEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHC
GMDEPELKIIDVFICKLRKKLANAAGGANYIETVWGRGYVLREPDGAAEFLETA
CCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCEEEECCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA