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The map label for this gene is mraY

Identifier: 15889381

GI number: 15889381

Start: 2061155

End: 2062255

Strand: Reverse

Name: mraY

Synonym: Atu2097

Alternate gene names: 15889381

Gene position: 2062255-2061155 (Counterclockwise)

Preceding gene: 15889382

Following gene: 15889380

Centisome position: 72.57

GC content: 58.95

Gene sequence:

>1101_bases
ATGCTGATCTGGCTCGTCGAACTGTCGGACAAAGTTCAACTGTTCAACCTCTTCCGGTACATCACCTTCCGGGCGGGTGC
TGCAATGTTCACCTCTGCGTTGATCGTGTTCCTGTTCGGACCGGCGATCATCAACTCGCTGCGCGTGCGCCAGGGCAAGG
GCCAGCCGATCCGCGCCGACGGGCCGCAGACGCATTTCAAGAAGGCCGGTACGCCGACCATGGGCGGACTGATGATCCTT
GCGGGCATTCTCGGCGGTTCGCTGCTCTGGGGTGACCTGTCGAACGTCTATGTCGTTGCCGTTCTGATGGTGACGCTCGG
TTTCGGCGCCATCGGCTTTTACGACGATTATCTGAAGGTGACGAAGCAGAGCGACAAGGGTTTCTCCGGCAAGGCCCGTC
TCGGCATCGAATTTCTGATTGCGGCGATTGCCGTGTTCTTCATGATGAAGATGGCGCTTGCCTCCGCACCGCATGGCGGC
ACGCTCGGCAGCTCCATCGCCTTTCCCTTCTTCAAGGAATTCGTGATCAATCTCGGTTATTTCTTCGTACTGTTCGGTGC
TTTTGTCATCGTCGGTGCGGGCAATGCGGTGAACCTGACCGATGGTCTCGATGGTCTCGCCATCGTGCCGGTCATGATCG
CTGCCGCCACCTTCGGCGTGATCGCCTATCTCGCCGGTAATGCGGTTTTTGCCAATTACCTGCAGATCAATTTCGTGCCC
GGTACGGGTGAACTCGCCGTCATCGTCGGTGCCGTCATCGGCGCGGGCCTCGGTTTTCTGTGGTTCAATGCGCCGCCCGC
CGCCATCTTCATGGGCGATACGGGTTCGCTGGCGCTCGGCGGTCTGATTGGCTCCATCGCCGTCGCCACCAAGCATGAGA
TCGTCATGGTCATCGTTGGTGGTCTGTTCGTCATGGAAACGCTGTCGGTCATCATCCAGGTCTTCTGGTTTAAACGCACC
GGCCGCCGCGTCTTCCTGATGGCGCCGATCCATCACCATTTCGAGAAAAAGGGCTGGACGGAAAGCCAGGTGGTTATCCG
TTTCTGGATCATCTCCGTCGGCCTCGCGCTGCTCGGTCTTGCCACCCTGAAGCTGAGGTGA

Upstream 100 bases:

>100_bases
GGCTTGGTTTCGGCAAGATTGTCGCCGCCCTGCTTGACAAGTATCCGGCATTCCCCGAGACGGAACGCCAAGTCTGAAAT
AGCCTTTTGAAAGGGCAATT

Downstream 100 bases:

>100_bases
GCGATGATCCCGGTCACGTCGTTTAGGGGTAAGAAAGTCGCTCTCTTCGGGCTCGGCGGTTCCGGTCTCGTCACCGCCCG
CGCGCTGGTTGCCGGTGGTG

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MLIWLVELSDKVQLFNLFRYITFRAGAAMFTSALIVFLFGPAIINSLRVRQGKGQPIRADGPQTHFKKAGTPTMGGLMIL
AGILGGSLLWGDLSNVYVVAVLMVTLGFGAIGFYDDYLKVTKQSDKGFSGKARLGIEFLIAAIAVFFMMKMALASAPHGG
TLGSSIAFPFFKEFVINLGYFFVLFGAFVIVGAGNAVNLTDGLDGLAIVPVMIAAATFGVIAYLAGNAVFANYLQINFVP
GTGELAVIVGAVIGAGLGFLWFNAPPAAIFMGDTGSLALGGLIGSIAVATKHEIVMVIVGGLFVMETLSVIIQVFWFKRT
GRRVFLMAPIHHHFEKKGWTESQVVIRFWIISVGLALLGLATLKLR

Sequences:

>Translated_366_residues
MLIWLVELSDKVQLFNLFRYITFRAGAAMFTSALIVFLFGPAIINSLRVRQGKGQPIRADGPQTHFKKAGTPTMGGLMIL
AGILGGSLLWGDLSNVYVVAVLMVTLGFGAIGFYDDYLKVTKQSDKGFSGKARLGIEFLIAAIAVFFMMKMALASAPHGG
TLGSSIAFPFFKEFVINLGYFFVLFGAFVIVGAGNAVNLTDGLDGLAIVPVMIAAATFGVIAYLAGNAVFANYLQINFVP
GTGELAVIVGAVIGAGLGFLWFNAPPAAIFMGDTGSLALGGLIGSIAVATKHEIVMVIVGGLFVMETLSVIIQVFWFKRT
GRRVFLMAPIHHHFEKKGWTESQVVIRFWIISVGLALLGLATLKLR
>Mature_366_residues
MLIWLVELSDKVQLFNLFRYITFRAGAAMFTSALIVFLFGPAIINSLRVRQGKGQPIRADGPQTHFKKAGTPTMGGLMIL
AGILGGSLLWGDLSNVYVVAVLMVTLGFGAIGFYDDYLKVTKQSDKGFSGKARLGIEFLIAAIAVFFMMKMALASAPHGG
TLGSSIAFPFFKEFVINLGYFFVLFGAFVIVGAGNAVNLTDGLDGLAIVPVMIAAATFGVIAYLAGNAVFANYLQINFVP
GTGELAVIVGAVIGAGLGFLWFNAPPAAIFMGDTGSLALGGLIGSIAVATKHEIVMVIVGGLFVMETLSVIIQVFWFKRT
GRRVFLMAPIHHHFEKKGWTESQVVIRFWIISVGLALLGLATLKLR

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily

Homologues:

Organism=Escherichia coli, GI1786275, Length=367, Percent_Identity=50.408719346049, Blast_Score=335, Evalue=2e-93,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MRAY_AGRT5 (Q8UDM5)

Other databases:

- EMBL:   AE007869
- PIR:   AB2834
- PIR:   F97611
- RefSeq:   NP_355062.1
- STRING:   Q8UDM5
- GeneID:   1134135
- GenomeReviews:   AE007869_GR
- KEGG:   atu:Atu2097
- eggNOG:   COG0472
- HOGENOM:   HBG708263
- OMA:   TFWQFRN
- PhylomeDB:   Q8UDM5
- ProtClustDB:   PRK00108
- BioCyc:   ATUM176299-1:ATU2097-MONOMER
- HAMAP:   MF_00038
- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480
- PANTHER:   PTHR22926
- PANTHER:   PTHR22926:SF3
- TIGRFAMs:   TIGR00445

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1

EC number: =2.7.8.13

Molecular weight: Translated: 39127; Mature: 39127

Theoretical pI: Translated: 10.31; Mature: 10.31

Prosite motif: PS01347 MRAY_1; PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xf9caf98)-; HASH(0xf5b78f4)-; HASH(0xfb26a94)-; HASH(0xe83b394)-; HASH(0xfe4bb60)-; HASH(0xf59a424)-; HASH(0xf10f0f4)-; HASH(0xf7f0f80)-; HASH(0xfe431e0)-; HASH(0xfbe34b0)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIWLVELSDKVQLFNLFRYITFRAGAAMFTSALIVFLFGPAIINSLRVRQGKGQPIRAD
CEEEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
GPQTHFKKAGTPTMGGLMILAGILGGSLLWGDLSNVYVVAVLMVTLGFGAIGFYDDYLKV
CCHHHHHCCCCCCHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHH
TKQSDKGFSGKARLGIEFLIAAIAVFFMMKMALASAPHGGTLGSSIAFPFFKEFVINLGY
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
FFVLFGAFVIVGAGNAVNLTDGLDGLAIVPVMIAAATFGVIAYLAGNAVFANYLQINFVP
HHHHHHHHHHEECCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEEC
GTGELAVIVGAVIGAGLGFLWFNAPPAAIFMGDTGSLALGGLIGSIAVATKHEIVMVIVG
CCCCHHHHHHHHHHCCHHEEEECCCCCEEEECCCCCHHHHHHHHHHHHHCCCCEEEEHHH
GLFVMETLSVIIQVFWFKRTGRRVFLMAPIHHHFEKKGWTESQVVIRFWIISVGLALLGL
HHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
ATLKLR
HHHCCH
>Mature Secondary Structure
MLIWLVELSDKVQLFNLFRYITFRAGAAMFTSALIVFLFGPAIINSLRVRQGKGQPIRAD
CEEEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
GPQTHFKKAGTPTMGGLMILAGILGGSLLWGDLSNVYVVAVLMVTLGFGAIGFYDDYLKV
CCHHHHHCCCCCCHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHH
TKQSDKGFSGKARLGIEFLIAAIAVFFMMKMALASAPHGGTLGSSIAFPFFKEFVINLGY
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
FFVLFGAFVIVGAGNAVNLTDGLDGLAIVPVMIAAATFGVIAYLAGNAVFANYLQINFVP
HHHHHHHHHHEECCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEEC
GTGELAVIVGAVIGAGLGFLWFNAPPAAIFMGDTGSLALGGLIGSIAVATKHEIVMVIVG
CCCCHHHHHHHHHHCCHHEEEECCCCCEEEECCCCCHHHHHHHHHHHHHCCCCEEEEHHH
GLFVMETLSVIIQVFWFKRTGRRVFLMAPIHHHFEKKGWTESQVVIRFWIISVGLALLGL
HHHHHHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
ATLKLR
HHHCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194