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The map label for this gene is cfa [H]

Identifier: 15889271

GI number: 15889271

Start: 1945698

End: 1946930

Strand: Direct

Name: cfa [H]

Synonym: Atu1979

Alternate gene names: 15889271

Gene position: 1945698-1946930 (Clockwise)

Preceding gene: 15889270

Following gene: 15889272

Centisome position: 68.47

GC content: 56.85

Gene sequence:

>1233_bases
ATGACCCCGTTTGAAAATCTCTCGGAACTACCTGCACAGAACACGCGCTTCAACGGTCGTGCTGGCATGGGCACATGGCT
CGTCAACCGGCTGCTGAACAATATCGAGCGCGGACGCCTGCGTGTAACCCTTCCCGGCGGTGGAACCATCGAAAAATCGG
GGCATCAGGAAGGTAGCGAGGCCATTCTCATGCTGCACAACTGGCGGGCCATCCGCAGGGTGCTCGTCAATGGCGATATC
GGCTTCGCGGAAGGCTTCATCGAAAATGACTGGTCTACGCCTGATCTGACGGCACTCATCCGTTTCGCCGCTCAGAATCA
AGATGCATTCGCAAGGTCGACGCGCGGCAGCCTGCCAATGCGTCTCATCAACCGCATGGCACATGCTCTGAACGCCAATA
CCAGACGCGGCAGCCGCCGTAATATCGAAGCACATTACGATCTCGGCAACGAGTTCTACCGGCAATGGCTGGATCCCTCG
ATGCTCTATTCCTCGGCGATTTTCGACGACACCACGCCCACCCTCGAAGCCGCGCAACGGAAGAAACTCGAGCGTATTGC
CGAGAAGCTGCAGCTAACCGGAAATAACAGCGTACTCGAAATCGGCTGCGGCTGGGGTGCACTCGCCATCCACCTCGCCA
CGCAACAGAATGCCGATGTGACCGGCATCACCCTTTCCCCCTCCCAGTTGCGCTGGGCAGAAAATGCAGCAGAGAAAGAA
AGTAAGGCTGGCCGGATCGATCTTCGGCTGCAGGATTACCGCGACGTGCAGGGTCAATTCGACAATATCGTCTCGGTGGA
GATGTTTGAGGCCGTCGGCGAATCCTATTGGCCAAGCTATTTCGAAATGCTGAAACGCTGCCTTAAACCCGGCGGCCGTG
CGGTGCTGCAAATCATCTCCATTGACGAAAGCCGCTTCGATACCTATCGGCGCAAGGCTGACTTCATTCAGAAATACGTC
TTCCCGGGCGGTTTCCTGCCATCCGATTCAGCGCTTGAAAAATCCGTCGGACAAGCCGGCCTGAAACTCACGGAGACGGA
GCTTTTCGGACAGTCCTATGCGCTCACACTGGCAGAATGGCGCCAGCGCTTCCATGCCCGGTGGCAAACGATTTCCCTGC
TCGGCTTCGATGAGCGCTTTCGGCGGCTCTGGGATTATTACCTCTGCTACTGCGAAGCGGGTTTTGCCGAGGGAACCATA
AATGTCGGCCTGTACACGATAGAACACGGATGA

Upstream 100 bases:

>100_bases
ATCTGGCTGAAGGGCGTGCGGCTCAAAAAACGTCCGCTACCGCCCGCCGAGCCTGTCTCTTTCGTTCATCCTTCATCGTC
GCAAATCGAGGCCAGAATTC

Downstream 100 bases:

>100_bases
GGCGGGGCGAACAAGCGGAGAAAGACGATGAAAATCAGCAGATTGGCAATTGTATCCGCCCTCCTCCCGACGCTGGCGGG
CCTCAGTGCGGCAGCAGGCG

Product: cyclopropane-fatty-acyl-phospholipid synthase

Products: NA

Alternate protein names: CFA synthase; Cyclopropane fatty acid synthase [H]

Number of amino acids: Translated: 410; Mature: 409

Protein sequence:

>410_residues
MTPFENLSELPAQNTRFNGRAGMGTWLVNRLLNNIERGRLRVTLPGGGTIEKSGHQEGSEAILMLHNWRAIRRVLVNGDI
GFAEGFIENDWSTPDLTALIRFAAQNQDAFARSTRGSLPMRLINRMAHALNANTRRGSRRNIEAHYDLGNEFYRQWLDPS
MLYSSAIFDDTTPTLEAAQRKKLERIAEKLQLTGNNSVLEIGCGWGALAIHLATQQNADVTGITLSPSQLRWAENAAEKE
SKAGRIDLRLQDYRDVQGQFDNIVSVEMFEAVGESYWPSYFEMLKRCLKPGGRAVLQIISIDESRFDTYRRKADFIQKYV
FPGGFLPSDSALEKSVGQAGLKLTETELFGQSYALTLAEWRQRFHARWQTISLLGFDERFRRLWDYYLCYCEAGFAEGTI
NVGLYTIEHG

Sequences:

>Translated_410_residues
MTPFENLSELPAQNTRFNGRAGMGTWLVNRLLNNIERGRLRVTLPGGGTIEKSGHQEGSEAILMLHNWRAIRRVLVNGDI
GFAEGFIENDWSTPDLTALIRFAAQNQDAFARSTRGSLPMRLINRMAHALNANTRRGSRRNIEAHYDLGNEFYRQWLDPS
MLYSSAIFDDTTPTLEAAQRKKLERIAEKLQLTGNNSVLEIGCGWGALAIHLATQQNADVTGITLSPSQLRWAENAAEKE
SKAGRIDLRLQDYRDVQGQFDNIVSVEMFEAVGESYWPSYFEMLKRCLKPGGRAVLQIISIDESRFDTYRRKADFIQKYV
FPGGFLPSDSALEKSVGQAGLKLTETELFGQSYALTLAEWRQRFHARWQTISLLGFDERFRRLWDYYLCYCEAGFAEGTI
NVGLYTIEHG
>Mature_409_residues
TPFENLSELPAQNTRFNGRAGMGTWLVNRLLNNIERGRLRVTLPGGGTIEKSGHQEGSEAILMLHNWRAIRRVLVNGDIG
FAEGFIENDWSTPDLTALIRFAAQNQDAFARSTRGSLPMRLINRMAHALNANTRRGSRRNIEAHYDLGNEFYRQWLDPSM
LYSSAIFDDTTPTLEAAQRKKLERIAEKLQLTGNNSVLEIGCGWGALAIHLATQQNADVTGITLSPSQLRWAENAAEKES
KAGRIDLRLQDYRDVQGQFDNIVSVEMFEAVGESYWPSYFEMLKRCLKPGGRAVLQIISIDESRFDTYRRKADFIQKYVF
PGGFLPSDSALEKSVGQAGLKLTETELFGQSYALTLAEWRQRFHARWQTISLLGFDERFRRLWDYYLCYCEAGFAEGTIN
VGLYTIEHG

Specific function: Transfers a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge [H]

COG id: COG2230

COG function: function code M; Cyclopropane fatty acid synthase and related methyltransferases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CFA/CMAS family [H]

Homologues:

Organism=Escherichia coli, GI1787951, Length=333, Percent_Identity=35.7357357357357, Blast_Score=185, Evalue=5e-48,
Organism=Caenorhabditis elegans, GI133904226, Length=391, Percent_Identity=36.8286445012788, Blast_Score=254, Evalue=7e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003333 [H]

Pfam domain/function: PF02353 CMAS [H]

EC number: =2.1.1.79 [H]

Molecular weight: Translated: 46525; Mature: 46394

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPFENLSELPAQNTRFNGRAGMGTWLVNRLLNNIERGRLRVTLPGGGTIEKSGHQEGSE
CCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCC
AILMLHNWRAIRRVLVNGDIGFAEGFIENDWSTPDLTALIRFAAQNQDAFARSTRGSLPM
EEEEEECHHHHHHHHHCCCCCHHCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHCCCCCHH
RLINRMAHALNANTRRGSRRNIEAHYDLGNEFYRQWLDPSMLYSSAIFDDTTPTLEAAQR
HHHHHHHHHHCCCCCCCCCCCCEEEECCCHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHH
KKLERIAEKLQLTGNNSVLEIGCGWGALAIHLATQQNADVTGITLSPSQLRWAENAAEKE
HHHHHHHHHHEECCCCCEEEEECCCCEEEEEEEECCCCCEEEEEECHHHHHHHHHHHHHH
SKAGRIDLRLQDYRDVQGQFDNIVSVEMFEAVGESYWPSYFEMLKRCLKPGGRAVLQIIS
HCCCEEEEEEHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEEEE
IDESRFDTYRRKADFIQKYVFPGGFLPSDSALEKSVGQAGLKLTETELFGQSYALTLAEW
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCEEEHHHHHCCHHHHHHHHH
RQRFHARWQTISLLGFDERFRRLWDYYLCYCEAGFAEGTINVGLYTIEHG
HHHHHHHHHEEEEECHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEECC
>Mature Secondary Structure 
TPFENLSELPAQNTRFNGRAGMGTWLVNRLLNNIERGRLRVTLPGGGTIEKSGHQEGSE
CCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCC
AILMLHNWRAIRRVLVNGDIGFAEGFIENDWSTPDLTALIRFAAQNQDAFARSTRGSLPM
EEEEEECHHHHHHHHHCCCCCHHCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHCCCCCHH
RLINRMAHALNANTRRGSRRNIEAHYDLGNEFYRQWLDPSMLYSSAIFDDTTPTLEAAQR
HHHHHHHHHHCCCCCCCCCCCCEEEECCCHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHH
KKLERIAEKLQLTGNNSVLEIGCGWGALAIHLATQQNADVTGITLSPSQLRWAENAAEKE
HHHHHHHHHHEECCCCCEEEEECCCCEEEEEEEECCCCCEEEEEECHHHHHHHHHHHHHH
SKAGRIDLRLQDYRDVQGQFDNIVSVEMFEAVGESYWPSYFEMLKRCLKPGGRAVLQIIS
HCCCEEEEEEHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEEEE
IDESRFDTYRRKADFIQKYVFPGGFLPSDSALEKSVGQAGLKLTETELFGQSYALTLAEW
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCEEEHHHHHCCHHHHHHHHH
RQRFHARWQTISLLGFDERFRRLWDYYLCYCEAGFAEGTINVGLYTIEHG
HHHHHHHHHEEEEECHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]