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The map label for this gene is fabD [H]

Identifier: 15888434

GI number: 15888434

Start: 1083983

End: 1084978

Strand: Direct

Name: fabD [H]

Synonym: Atu1094

Alternate gene names: 15888434

Gene position: 1083983-1084978 (Clockwise)

Preceding gene: 159184611

Following gene: 15888435

Centisome position: 38.15

GC content: 62.45

Gene sequence:

>996_bases
ATGGAAGTCCGAAAGAATAAAGGCAAGGCCAGACAAGAAGGACGACATCCCATGGGTATTGCATTCACATTTCCCGGTCA
GGGAAGCCAGGCCGTCGGCATGGGCAAGGAGCTGGCGGACACCTACCCGGAAGCGCGCGCCGTGTTTCAGGAAGTCGACG
ACGCGCTCGACCAGAAGCTTTCCGACATCATGTGGAACGGACCGGAAGAAACGCTGACGCTGACGGCCAACGCTCAGCCG
GCGCTCATGGCCGTTTCGATGGCGGTGATGCGCGTTCTGGAAGCGCGTGGCCTGAAGCTGTCCGATACGGTGTCTTATGT
GGCCGGCCATTCGCTCGGTGAATATTCGGCGCTCTGTGCCGCCGGCACCTTCTCGATTGCCGATACCGCCCGTCTTCTGC
GCATCCGCGGCAATGCCATGCAGGCCGCCGTGCCGGTCGGCGAGGGTGCCATGGCTGCAATCATCGGGCTCGAGCACGAT
GCCGTTTCCGCCATTTGCGAGGAAGCCGGCATTCTCGGCGTCTGCCAGATCGCCAACGACAATGGCGGCGGCCAGCTGGT
CATTTCTGGTAGCAAGACTGCCGTTGAAAAGGCCGCAGCGATCGCTTCCGAAAAGGGCGCCAAGCGCGCCATCATGCTGC
CGGTTTCCGCCCCCTTCCACTCCGCGCTGATGGCGCCGGCGGCGGAAGCGATGCGCGAGGCGCTGGCGAAAGTTGAAAAG
CACAATCCGGTCGTGCCTGTTGTCGCCAATGTGCGCGCCGCTCCCGTTTCCGACGCCAATGAGATTGCCGCTTTGCTGGT
CGAGCAGGTGACGGGCCAGGTGCGCTGGCGCGAGACGGTGGAATGGTTTGCCGCCAATAACGTGACCCAGCTTTACGAAA
TCGGCTCCGGCAAGGTGCTGACAGGCCTTGCCCGCCGTATCGACAAGACGGTGAACGGCGTTGCCGTCAACGGTGCGGCC
GATATCGACCAGCTGCTAGCCACGCTTATCGGCTAA

Upstream 100 bases:

>100_bases
GAAAAAATATGACTAAAAGAAAGGGGAAAACGGGTTTGTAAAACCCCGGGCAATGGCCCGTTATAGGGCTTCAAGCTTGA
CTTCGCCGACGGGAATGTGA

Downstream 100 bases:

>100_bases
GGCGGAAGAGCCCCATAATATCCATCGGGCGCGACAGCGCCAACCATTTGGTCCGAAGCTCTAAAGAAGGAATAGGACAT
GTTAGATTTAACAGGCCGCA

Product: malonyl-CoA:acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MEVRKNKGKARQEGRHPMGIAFTFPGQGSQAVGMGKELADTYPEARAVFQEVDDALDQKLSDIMWNGPEETLTLTANAQP
ALMAVSMAVMRVLEARGLKLSDTVSYVAGHSLGEYSALCAAGTFSIADTARLLRIRGNAMQAAVPVGEGAMAAIIGLEHD
AVSAICEEAGILGVCQIANDNGGGQLVISGSKTAVEKAAAIASEKGAKRAIMLPVSAPFHSALMAPAAEAMREALAKVEK
HNPVVPVVANVRAAPVSDANEIAALLVEQVTGQVRWRETVEWFAANNVTQLYEIGSGKVLTGLARRIDKTVNGVAVNGAA
DIDQLLATLIG

Sequences:

>Translated_331_residues
MEVRKNKGKARQEGRHPMGIAFTFPGQGSQAVGMGKELADTYPEARAVFQEVDDALDQKLSDIMWNGPEETLTLTANAQP
ALMAVSMAVMRVLEARGLKLSDTVSYVAGHSLGEYSALCAAGTFSIADTARLLRIRGNAMQAAVPVGEGAMAAIIGLEHD
AVSAICEEAGILGVCQIANDNGGGQLVISGSKTAVEKAAAIASEKGAKRAIMLPVSAPFHSALMAPAAEAMREALAKVEK
HNPVVPVVANVRAAPVSDANEIAALLVEQVTGQVRWRETVEWFAANNVTQLYEIGSGKVLTGLARRIDKTVNGVAVNGAA
DIDQLLATLIG
>Mature_331_residues
MEVRKNKGKARQEGRHPMGIAFTFPGQGSQAVGMGKELADTYPEARAVFQEVDDALDQKLSDIMWNGPEETLTLTANAQP
ALMAVSMAVMRVLEARGLKLSDTVSYVAGHSLGEYSALCAAGTFSIADTARLLRIRGNAMQAAVPVGEGAMAAIIGLEHD
AVSAICEEAGILGVCQIANDNGGGQLVISGSKTAVEKAAAIASEKGAKRAIMLPVSAPFHSALMAPAAEAMREALAKVEK
HNPVVPVVANVRAAPVSDANEIAALLVEQVTGQVRWRETVEWFAANNVTQLYEIGSGKVLTGLARRIDKTVNGVAVNGAA
DIDQLLATLIG

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=318, Percent_Identity=32.3899371069182, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI27477045, Length=105, Percent_Identity=37.1428571428571, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1787334, Length=298, Percent_Identity=47.3154362416107, Blast_Score=233, Evalue=2e-62,
Organism=Caenorhabditis elegans, GI71984332, Length=293, Percent_Identity=29.0102389078498, Blast_Score=123, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17550940, Length=290, Percent_Identity=28.6206896551724, Blast_Score=98, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24665753, Length=311, Percent_Identity=32.7974276527331, Blast_Score=133, Evalue=2e-31,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 34580; Mature: 34580

Theoretical pI: Translated: 5.44; Mature: 5.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVRKNKGKARQEGRHPMGIAFTFPGQGSQAVGMGKELADTYPEARAVFQEVDDALDQKL
CCCCCCCCCHHHCCCCCCEEEEECCCCCCCCCCCCHHHHHHCHHHHHHHHHHHHHHHHHH
SDIMWNGPEETLTLTANAQPALMAVSMAVMRVLEARGLKLSDTVSYVAGHSLGEYSALCA
HHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHH
AGTFSIADTARLLRIRGNAMQAAVPVGEGAMAAIIGLEHDAVSAICEEAGILGVCQIAND
CCCCHHHHHHHHHHHCCCCCEEEEECCCCCEEEEEECCHHHHHHHHHHCCCEEEEEEECC
NGGGQLVISGSKTAVEKAAAIASEKGAKRAIMLPVSAPFHSALMAPAAEAMREALAKVEK
CCCCEEEEECCHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
HNPVVPVVANVRAAPVSDANEIAALLVEQVTGQVRWRETVEWFAANNVTQLYEIGSGKVL
CCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHEEHCCCCCHHH
TGLARRIDKTVNGVAVNGAADIDQLLATLIG
HHHHHHHHHHHCCEEECCHHHHHHHHHHHCC
>Mature Secondary Structure
MEVRKNKGKARQEGRHPMGIAFTFPGQGSQAVGMGKELADTYPEARAVFQEVDDALDQKL
CCCCCCCCCHHHCCCCCCEEEEECCCCCCCCCCCCHHHHHHCHHHHHHHHHHHHHHHHHH
SDIMWNGPEETLTLTANAQPALMAVSMAVMRVLEARGLKLSDTVSYVAGHSLGEYSALCA
HHHHCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHH
AGTFSIADTARLLRIRGNAMQAAVPVGEGAMAAIIGLEHDAVSAICEEAGILGVCQIAND
CCCCHHHHHHHHHHHCCCCCEEEEECCCCCEEEEEECCHHHHHHHHHHCCCEEEEEEECC
NGGGQLVISGSKTAVEKAAAIASEKGAKRAIMLPVSAPFHSALMAPAAEAMREALAKVEK
CCCCEEEEECCHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
HNPVVPVVANVRAAPVSDANEIAALLVEQVTGQVRWRETVEWFAANNVTQLYEIGSGKVL
CCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHEEHCCCCCHHH
TGLARRIDKTVNGVAVNGAADIDQLLATLIG
HHHHHHHHHHHCCEEECCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9534248; 9384377 [H]