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The map label for this gene is yqeF [C]

Identifier: 57652614

GI number: 57652614

Start: 429930

End: 431111

Strand: Direct

Name: yqeF [C]

Synonym: SACOL0426

Alternate gene names: 57652614

Gene position: 429930-431111 (Clockwise)

Preceding gene: 57652612

Following gene: 57652620

Centisome position: 15.3

GC content: 38.32

Gene sequence:

>1182_bases
ATGACGAGAGTCGTATTAGCAGCAGCATACAGGACACCTATTGGCGTTTTTGGAGGTGCGTTTAAAGACGTGCCAGCCTA
TGATTTAGGTGCGACTTTAATAGAACATATTATTAAAGAGACGGGTTTGAATCCAAGTGAGATTGATGAAGTTATCATCG
GTAACGTACTACAAGCAGGACAAGGACAAAATCCAGCACGAATTGCTGCTATGAAAGGTGGCTTGCCAGAAACAGTACCT
GCATTTACGGTGAATAAAGTATGTGGTTCTGGGTTAAAGTCGATTCAATTAGCATATCAATCTATTGTGACTGGTGAAAA
TGACATCGTGCTAGCTGGCGGTATGGAGAATATGTCTCAATCACCAATGCTTGTCAACAACAGTCGCTTTGGTTTTAAAA
TGGGACATCAATCAATGGTTGATAGCATGGTATATGATGGTTTAACAGATGTATTTAATCAATATCATATGGGTATTACT
GCTGAAAATTTAGCAGAGCAATATGGTATTTCAAGAGAAGAACAAGATACATTTGCTGTAAACTCACAACAAAAAGCAGT
ACGTGCACAGCAAAATGGTGAATTTGATAGTGAAATAGTTCCAGTATCGATTCCTCAACGTAAAGGTGAACCAATCGTAG
TCACTAAGGATGAAGGTGTACGTGAAAATGTATCAGTCGAAAAATTAAGTCGATTAAGACCAGCTTTCAAAAAAGACGGT
ACAGTTACAGCAGGTAATGCATCAGGAATCAATGATGGTGCTGCGATGATGTTAGTCATGTCAGAAGACAAAGCTAAAGA
ATTAAATATCGAACCATTGGCAGTGCTTGATGGCTTTGGAAGTCATGGTGTAGATCCTTCTATTATGGGTATTGCACCAG
TTGGCGCTGTAGAAAAGGCTTTGAAACGTAGTAAAAAAGAATTAAGCGATATTGATGTATTTGAATTAAATGAAGCATTT
GCAGCACAATCATTAGCTGTTGATCGTGAATTAAAATTACCTCCTGAAAAGGTGAATGTTAAAGGTGGCGCTATTGCATT
AGGACATCCTATTGGTGCATCTGGTGCTAGAGTATTAGTGACATTATTGCATCAACTGAATGATGAAGTTGAAACTGGTT
TAACATCATTGTGTATTGGTGGCGGTCAAGCTATCGCTGCAGTTGTATCAAAGTATAAATAA

Upstream 100 bases:

>100_bases
TACGTAGCAATTGGTTTCATAAATTGGATGTTAGTGGCGTATTGGTTCATTAGACGTATTAGTAATAAAATTGTATATAT
CATAAGGAGATGAATATGAC

Downstream 100 bases:

>100_bases
TAAGAAAACAGGTTATCACAACAGTATTAATTACATGTTGGCATAACCTGTTTTTATTTGTTTATGGATTTATTGGGTAA
TATTAGTCATTTGATGGTTT

Product: acetyl-CoA acetyltransferase

Products: NA

Alternate protein names: Acetoacetyl-CoA thiolase [H]

Number of amino acids: Translated: 393; Mature: 392

Protein sequence:

>393_residues
MTRVVLAAAYRTPIGVFGGAFKDVPAYDLGATLIEHIIKETGLNPSEIDEVIIGNVLQAGQGQNPARIAAMKGGLPETVP
AFTVNKVCGSGLKSIQLAYQSIVTGENDIVLAGGMENMSQSPMLVNNSRFGFKMGHQSMVDSMVYDGLTDVFNQYHMGIT
AENLAEQYGISREEQDTFAVNSQQKAVRAQQNGEFDSEIVPVSIPQRKGEPIVVTKDEGVRENVSVEKLSRLRPAFKKDG
TVTAGNASGINDGAAMMLVMSEDKAKELNIEPLAVLDGFGSHGVDPSIMGIAPVGAVEKALKRSKKELSDIDVFELNEAF
AAQSLAVDRELKLPPEKVNVKGGAIALGHPIGASGARVLVTLLHQLNDEVETGLTSLCIGGGQAIAAVVSKYK

Sequences:

>Translated_393_residues
MTRVVLAAAYRTPIGVFGGAFKDVPAYDLGATLIEHIIKETGLNPSEIDEVIIGNVLQAGQGQNPARIAAMKGGLPETVP
AFTVNKVCGSGLKSIQLAYQSIVTGENDIVLAGGMENMSQSPMLVNNSRFGFKMGHQSMVDSMVYDGLTDVFNQYHMGIT
AENLAEQYGISREEQDTFAVNSQQKAVRAQQNGEFDSEIVPVSIPQRKGEPIVVTKDEGVRENVSVEKLSRLRPAFKKDG
TVTAGNASGINDGAAMMLVMSEDKAKELNIEPLAVLDGFGSHGVDPSIMGIAPVGAVEKALKRSKKELSDIDVFELNEAF
AAQSLAVDRELKLPPEKVNVKGGAIALGHPIGASGARVLVTLLHQLNDEVETGLTSLCIGGGQAIAAVVSKYK
>Mature_392_residues
TRVVLAAAYRTPIGVFGGAFKDVPAYDLGATLIEHIIKETGLNPSEIDEVIIGNVLQAGQGQNPARIAAMKGGLPETVPA
FTVNKVCGSGLKSIQLAYQSIVTGENDIVLAGGMENMSQSPMLVNNSRFGFKMGHQSMVDSMVYDGLTDVFNQYHMGITA
ENLAEQYGISREEQDTFAVNSQQKAVRAQQNGEFDSEIVPVSIPQRKGEPIVVTKDEGVRENVSVEKLSRLRPAFKKDGT
VTAGNASGINDGAAMMLVMSEDKAKELNIEPLAVLDGFGSHGVDPSIMGIAPVGAVEKALKRSKKELSDIDVFELNEAFA
AQSLAVDRELKLPPEKVNVKGGAIALGHPIGASGARVLVTLLHQLNDEVETGLTSLCIGGGQAIAAVVSKYK

Specific function: Unknown

COG id: COG0183

COG function: function code I; Acetyl-CoA acetyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiolase family [H]

Homologues:

Organism=Homo sapiens, GI148539872, Length=391, Percent_Identity=50.6393861892583, Blast_Score=383, Evalue=1e-106,
Organism=Homo sapiens, GI167614485, Length=388, Percent_Identity=45.1030927835052, Blast_Score=329, Evalue=2e-90,
Organism=Homo sapiens, GI4557237, Length=392, Percent_Identity=44.1326530612245, Blast_Score=321, Evalue=7e-88,
Organism=Homo sapiens, GI4501853, Length=392, Percent_Identity=44.6428571428571, Blast_Score=301, Evalue=5e-82,
Organism=Homo sapiens, GI4504327, Length=427, Percent_Identity=33.7236533957845, Blast_Score=209, Evalue=3e-54,
Organism=Homo sapiens, GI194353979, Length=393, Percent_Identity=35.1145038167939, Blast_Score=193, Evalue=3e-49,
Organism=Escherichia coli, GI87082165, Length=392, Percent_Identity=53.0612244897959, Blast_Score=418, Evalue=1e-118,
Organism=Escherichia coli, GI1788554, Length=393, Percent_Identity=53.4351145038168, Blast_Score=390, Evalue=1e-109,
Organism=Escherichia coli, GI1787663, Length=401, Percent_Identity=40.8977556109726, Blast_Score=290, Evalue=1e-79,
Organism=Escherichia coli, GI48994986, Length=401, Percent_Identity=42.8927680798005, Blast_Score=273, Evalue=2e-74,
Organism=Escherichia coli, GI1788683, Length=400, Percent_Identity=31, Blast_Score=189, Evalue=3e-49,
Organism=Caenorhabditis elegans, GI133906874, Length=390, Percent_Identity=45.6410256410256, Blast_Score=334, Evalue=4e-92,
Organism=Caenorhabditis elegans, GI25147385, Length=386, Percent_Identity=41.1917098445596, Blast_Score=292, Evalue=2e-79,
Organism=Caenorhabditis elegans, GI17535921, Length=391, Percent_Identity=41.4322250639386, Blast_Score=278, Evalue=3e-75,
Organism=Caenorhabditis elegans, GI17551802, Length=429, Percent_Identity=33.5664335664336, Blast_Score=209, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI17535917, Length=392, Percent_Identity=31.3775510204082, Blast_Score=177, Evalue=1e-44,
Organism=Saccharomyces cerevisiae, GI6325229, Length=394, Percent_Identity=45.6852791878173, Blast_Score=309, Evalue=6e-85,
Organism=Saccharomyces cerevisiae, GI6322031, Length=394, Percent_Identity=40.1015228426396, Blast_Score=251, Evalue=2e-67,
Organism=Drosophila melanogaster, GI24655093, Length=392, Percent_Identity=52.0408163265306, Blast_Score=399, Evalue=1e-111,
Organism=Drosophila melanogaster, GI17648125, Length=389, Percent_Identity=44.4730077120823, Blast_Score=318, Evalue=6e-87,
Organism=Drosophila melanogaster, GI24640423, Length=392, Percent_Identity=43.1122448979592, Blast_Score=306, Evalue=1e-83,
Organism=Drosophila melanogaster, GI17137578, Length=425, Percent_Identity=30.8235294117647, Blast_Score=185, Evalue=4e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020615
- InterPro:   IPR020610
- InterPro:   IPR020617
- InterPro:   IPR020613
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: =2.3.1.9 [H]

Molecular weight: Translated: 41676; Mature: 41545

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS00098 THIOLASE_1 ; PS00737 THIOLASE_2 ; PS00099 THIOLASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRVVLAAAYRTPIGVFGGAFKDVPAYDLGATLIEHIIKETGLNPSEIDEVIIGNVLQAG
CCEEEEEEHHHCCHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
QGQNPARIAAMKGGLPETVPAFTVNKVCGSGLKSIQLAYQSIVTGENDIVLAGGMENMSQ
CCCCCCEEEEECCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEECCCCCCCC
SPMLVNNSRFGFKMGHQSMVDSMVYDGLTDVFNQYHMGITAENLAEQYGISREEQDTFAV
CCEEEECCCCCEECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHEE
NSQQKAVRAQQNGEFDSEIVPVSIPQRKGEPIVVTKDEGVRENVSVEKLSRLRPAFKKDG
CCHHHHHHHHHCCCCCCCEEEEECCCCCCCCEEEECCCCCCCCCCHHHHHHHCHHHHCCC
TVTAGNASGINDGAAMMLVMSEDKAKELNIEPLAVLDGFGSHGVDPSIMGIAPVGAVEKA
CEEECCCCCCCCCEEEEEEEECCCCCCCCCCCEEEECCCCCCCCCCCCEEECCHHHHHHH
LKRSKKELSDIDVFELNEAFAAQSLAVDRELKLPPEKVNVKGGAIALGHPIGASGARVLV
HHHHHHHHHCCCCEECHHHHHHHHHHCCCCCCCCHHHCCCCCCEEEECCCCCCCHHHHHH
TLLHQLNDEVETGLTSLCIGGGQAIAAVVSKYK
HHHHHHCHHHHHCHHHHHHCCCHHHHHHHHHCC
>Mature Secondary Structure 
TRVVLAAAYRTPIGVFGGAFKDVPAYDLGATLIEHIIKETGLNPSEIDEVIIGNVLQAG
CEEEEEEHHHCCHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
QGQNPARIAAMKGGLPETVPAFTVNKVCGSGLKSIQLAYQSIVTGENDIVLAGGMENMSQ
CCCCCCEEEEECCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEECCCCCCCC
SPMLVNNSRFGFKMGHQSMVDSMVYDGLTDVFNQYHMGITAENLAEQYGISREEQDTFAV
CCEEEECCCCCEECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCHHEE
NSQQKAVRAQQNGEFDSEIVPVSIPQRKGEPIVVTKDEGVRENVSVEKLSRLRPAFKKDG
CCHHHHHHHHHCCCCCCCEEEEECCCCCCCCEEEECCCCCCCCCCHHHHHHHCHHHHCCC
TVTAGNASGINDGAAMMLVMSEDKAKELNIEPLAVLDGFGSHGVDPSIMGIAPVGAVEKA
CEEECCCCCCCCCEEEEEEEECCCCCCCCCCCEEEECCCCCCCCCCCCEEECCHHHHHHH
LKRSKKELSDIDVFELNEAFAAQSLAVDRELKLPPEKVNVKGGAIALGHPIGASGARVLV
HHHHHHHHHCCCCEECHHHHHHHHHHCCCCCCCCHHHCCCCCCEEEECCCCCCCHHHHHH
TLLHQLNDEVETGLTSLCIGGGQAIAAVVSKYK
HHHHHHCHHHHHCHHHHHHCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA