Click here to switch to the map view.

The map label for this gene is rbsK [H]

Identifier: 57652528

GI number: 57652528

Start: 293821

End: 294735

Strand: Reverse

Name: rbsK [H]

Synonym: SACOL0253

Alternate gene names: 57652528

Gene position: 294735-293821 (Counterclockwise)

Preceding gene: 57652529

Following gene: 57652527

Centisome position: 10.49

GC content: 37.6

Gene sequence:

>915_bases
ATGACCAACAAAGTTGTTATTTTAGGTTCAACGAATGTCGATCAATTTTTAACAGTTGAAAGATATGCACAACCAGGCGA
AACATTACATGTTGAAGAAGCACAAAAAGCATTCGGCGGAGGTAAAGGTGCCAACCAGGCTATTGCCACTGCACGCATGC
AAGCAGACACAACATTTATTACTAAAATTGGCACTGATGGCGTTGCTGATTTCATCTTAGAAGATTTTAAAGTAGCTCAT
ATTGATACATCATATATTATCAAAACAGCTGAAGCAAAAACGGGCCAAGCCTTTATCACTGTGAATGCAGAAGGACAAAA
CACCATCTATGTTTATGGTGGTGCGAATATGACGATGACACCTGAAGATGTTATTAACGCAAAAGACGCTATAATCAATG
CAGACTTTGTCGTTGCACAATTAGAAGTACCCATCCCGGCTATTATATCTGCATTTGAAATTGCCAAGGCACATGGTGTG
ACGACAGTATTAAATCCTGCACCAGCGAAAGCATTACCTAATGAATTATTATCATTAATCGATATTATTGTGCCAAACGA
AACAGAAGCCGAATTGTTATCTGGGATTAAAGTAACTAATGAACAATCTATGAAAGACAATGCCAATTACTTTTTATCTA
TAGGCATTAAGACTGTTTTGATTACGCTAGGTAAGCAAGGTACATATTTTGCTACTAAAAATCAAAGCCAACACATCGAA
GCTTATAAAGTAAATGCGATTGATACAACTGCTGCAGGCGACACATTTATTGGTGCATTTGTCAGTCGCTTAAACAAGTC
GCAAGATAACTTAGCAGATGCTATTGATTTTGGTAATAAAGCGAGCTCACTCACTGTACAAAAACACGGCGCGCAAGCAT
CTATTCCTCTACTAGAAGAAGTAAATCAAGTTTAA

Upstream 100 bases:

>100_bases
TAAAGGTAATATTCGTACTGGTGAAACAACGCCCTACTCTAATATTGCATTAGAATCGAATGTTACTTTTTAAAAGTTAT
AACTTGAAAGGAGCGTACAC

Downstream 100 bases:

>100_bases
ATGAATCAAACACAGCTATGATATGAAGGTTTAGCATATAACATGCAACATTCGTATATCATGGCTGTGCTTTTTTATCT
TTATAAAACATCATCTATTA

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MTNKVVILGSTNVDQFLTVERYAQPGETLHVEEAQKAFGGGKGANQAIATARMQADTTFITKIGTDGVADFILEDFKVAH
IDTSYIIKTAEAKTGQAFITVNAEGQNTIYVYGGANMTMTPEDVINAKDAIINADFVVAQLEVPIPAIISAFEIAKAHGV
TTVLNPAPAKALPNELLSLIDIIVPNETEAELLSGIKVTNEQSMKDNANYFLSIGIKTVLITLGKQGTYFATKNQSQHIE
AYKVNAIDTTAAGDTFIGAFVSRLNKSQDNLADAIDFGNKASSLTVQKHGAQASIPLLEEVNQV

Sequences:

>Translated_304_residues
MTNKVVILGSTNVDQFLTVERYAQPGETLHVEEAQKAFGGGKGANQAIATARMQADTTFITKIGTDGVADFILEDFKVAH
IDTSYIIKTAEAKTGQAFITVNAEGQNTIYVYGGANMTMTPEDVINAKDAIINADFVVAQLEVPIPAIISAFEIAKAHGV
TTVLNPAPAKALPNELLSLIDIIVPNETEAELLSGIKVTNEQSMKDNANYFLSIGIKTVLITLGKQGTYFATKNQSQHIE
AYKVNAIDTTAAGDTFIGAFVSRLNKSQDNLADAIDFGNKASSLTVQKHGAQASIPLLEEVNQV
>Mature_303_residues
TNKVVILGSTNVDQFLTVERYAQPGETLHVEEAQKAFGGGKGANQAIATARMQADTTFITKIGTDGVADFILEDFKVAHI
DTSYIIKTAEAKTGQAFITVNAEGQNTIYVYGGANMTMTPEDVINAKDAIINADFVVAQLEVPIPAIISAFEIAKAHGVT
TVLNPAPAKALPNELLSLIDIIVPNETEAELLSGIKVTNEQSMKDNANYFLSIGIKTVLITLGKQGTYFATKNQSQHIEA
YKVNAIDTTAAGDTFIGAFVSRLNKSQDNLADAIDFGNKASSLTVQKHGAQASIPLLEEVNQV

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=292, Percent_Identity=36.986301369863, Blast_Score=175, Evalue=4e-44,
Organism=Escherichia coli, GI1790193, Length=298, Percent_Identity=40.6040268456376, Blast_Score=218, Evalue=5e-58,
Organism=Escherichia coli, GI87082343, Length=306, Percent_Identity=27.4509803921569, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI87081971, Length=275, Percent_Identity=26.1818181818182, Blast_Score=84, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17532905, Length=303, Percent_Identity=36.6336633663366, Blast_Score=177, Evalue=5e-45,
Organism=Saccharomyces cerevisiae, GI6319884, Length=338, Percent_Identity=28.698224852071, Blast_Score=108, Evalue=1e-24,
Organism=Drosophila melanogaster, GI20128807, Length=302, Percent_Identity=34.7682119205298, Blast_Score=150, Evalue=9e-37,
Organism=Drosophila melanogaster, GI24583886, Length=300, Percent_Identity=28.6666666666667, Blast_Score=116, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 32449; Mature: 32318

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNKVVILGSTNVDQFLTVERYAQPGETLHVEEAQKAFGGGKGANQAIATARMQADTTFI
CCCCEEEEECCCHHHHEEHHHHCCCCCEEEHHHHHHHHCCCCCCCHHHHHHHHHCCCEEE
TKIGTDGVADFILEDFKVAHIDTSYIIKTAEAKTGQAFITVNAEGQNTIYVYGGANMTMT
EECCCCHHHHHHHHCCEEEEECHHHEEEECCCCCCEEEEEEECCCCEEEEEEECCCEEEC
PEDVINAKDAIINADFVVAQLEVPIPAIISAFEIAKAHGVTTVLNPAPAKALPNELLSLI
HHHHHCCHHHEEECCEEEEEECCCHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHH
DIIVPNETEAELLSGIKVTNEQSMKDNANYFLSIGIKTVLITLGKQGTYFATKNQSQHIE
HHHCCCCCHHHHHCCCEECCCCCCCCCCCEEEEECCEEEEEEECCCCCEEEECCCCCCEE
AYKVNAIDTTAAGDTFIGAFVSRLNKSQDNLADAIDFGNKASSLTVQKHGAQASIPLLEE
EEEEECEECCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHH
VNQV
HCCC
>Mature Secondary Structure 
TNKVVILGSTNVDQFLTVERYAQPGETLHVEEAQKAFGGGKGANQAIATARMQADTTFI
CCCEEEEECCCHHHHEEHHHHCCCCCEEEHHHHHHHHCCCCCCCHHHHHHHHHCCCEEE
TKIGTDGVADFILEDFKVAHIDTSYIIKTAEAKTGQAFITVNAEGQNTIYVYGGANMTMT
EECCCCHHHHHHHHCCEEEEECHHHEEEECCCCCCEEEEEEECCCCEEEEEEECCCEEEC
PEDVINAKDAIINADFVVAQLEVPIPAIISAFEIAKAHGVTTVLNPAPAKALPNELLSLI
HHHHHCCHHHEEECCEEEEEECCCHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHHHH
DIIVPNETEAELLSGIKVTNEQSMKDNANYFLSIGIKTVLITLGKQGTYFATKNQSQHIE
HHHCCCCCHHHHHCCCEECCCCCCCCCCCEEEEECCEEEEEEECCCCCEEEECCCCCCEE
AYKVNAIDTTAAGDTFIGAFVSRLNKSQDNLADAIDFGNKASSLTVQKHGAQASIPLLEE
EEEEECEECCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHH
VNQV
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]