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The map label for this gene is ureC

Identifier: 57652222

GI number: 57652222

Start: 2342319

End: 2344034

Strand: Direct

Name: ureC

Synonym: SACOL2282

Alternate gene names: 57652222

Gene position: 2342319-2344034 (Clockwise)

Preceding gene: 57652221

Following gene: 57652223

Centisome position: 83.37

GC content: 37.82

Gene sequence:

>1716_bases
ATGAGCTTTAAAATGACGCAAAATCAATATACGAGCTTATACGGTCCAACTGTTGGAGATTCCATTCGTTTAGGTGATAC
GAATCTATTTGCTCAAATAGAAAAAGACTATGCGGTTTATGGTGAAGAAGCTACTTTTGGTGGTGGTAAATCTATTAGAG
ACGGTATGGCGCAAAATCCTCGTGTAACACGTGATGACGTGAACGTTGCAGACCTTGTCATTTCTAATGCCGTTATTATC
GATTACGATAAAGTGGTTAAAGCTGATATAGGCATTAAAAATGGTTATATTTTCGCCATAGGTAATGCCGGCAACCCAGA
TATAATGGATAATGTCGACATTATTATAGGTTCAACAACAGATATCATTGCCGCTGAAGGTAAAATCGTCACTGCTGGTG
GTATTGATACTCATGTTCATTTTATTAATCCTGAACAAGCAGAGGTCGCATTAGAAAGTGGTATTACGACTCATATTGGT
GGTGGTACTGGTGCTTCAGAAGGTTCTAAAGCAACAACTGTAACTCCAGGTCCATGGCATATTCATAGAATGTTAGAAGC
TGCCGAAGGTTTACCGATTAATGTCGGTTTTACAGGTAAAGGACAAGCAACAAATCCAACTGCACTCATTGAACAAATCA
ATGCCGGAGCAATTGGATTAAAAGTACATGAAGACTGGGGTGCAACACCATCTGCTTTGAGTCATGCATTAGATGTTGCT
GATGAATTTGATGTTCAAATTGCATTACATGCAGATACTTTAAATGAAGCAGGATTTATGGAAGACACAATGGCTGCTGT
TAAAGACCGTGTACTTCATATGTACCATACTGAAGGTGCTGGTGGCGGTCATGCGCCTGATTTAATTAAATCCGCTGCAT
TTTCAAATATTTTACCTTCATCTACAAATCCAACTTTGCCTTATACACATAATACTGTAGATGAACATTTAGATATGGTA
ATGATTACTCACCATTTAAATGCGGCTATTCCTGAAGATATCGCATTCGCAGATTCACGTATTCGTAAAGAAACGATTGC
AGCAGAAGATGTTCTGCAAGATATGGGTGTATTCAGTATGATTAGTTCCGATTCACAAGCAATGGGCCGTGTAGGTGAAG
TAATTACACGAACATGGCAAGTAGCACATCGCATGAAAGAACAACGTGGTCCTTTAGATGGTGATTTTGAACATAATGAT
AATAATCGCATCAAACGTTATATCGCTAAATATACAATTAACCCAGCAATTACACATGGTATTTCTGAATATGTAGGATC
TATCGAGCCGGGCAAACTAGCTGACATTGTCTTATGGGACCCAATTTTCTTTGGGGTTAAACCTGAATTAGTTGTAAAGG
GCGGATTAATTAACTCTGCCGTAAATGGCGATGCAAATGGTTCTATACCTACATCTGAACCGATGAAGTACCGTAAAATG
TATGGTCAATACGGCGGAAACCTTACAAGTACGTCAATGACATTCGTGTCTAAAACTGCTTATGAAAATGGTATCAATCG
TGCATTAAATTTAAAACGCATGGTGCGTCCAGTTAAAAATATTAGACAATTATCTAAAGCAGATATGAAAAATAACAGTG
CAACACCTAAATTAGACGTTGATCCACAAACATATGAAGTATATGTAGATGGAGAAAAAATTACAAGTAATGCAGCAACT
GAGTTACCATTAACTCAAAGATACTTCTTATTCTAG

Upstream 100 bases:

>100_bases
AGTCACGTGTCTATCGCCCAACTGATGAAAATGATGAATATGCAGGTGTATTCGGAGATAACGGTGCTGAAAACGTGAAT
AAAAAAGGAGGAAAAAGATC

Downstream 100 bases:

>100_bases
GAGGAACATAGAATGATTGTTGAAGAAATCCAAGGCAATATTGCCAATTTGTCAAATTCAGAAAAACAAAAGCACGTCGA
AAAAGTATACCTTGAAAATT

Product: urease subunit alpha

Products: NA

Alternate protein names: Urea amidohydrolase subunit alpha

Number of amino acids: Translated: 571; Mature: 570

Protein sequence:

>571_residues
MSFKMTQNQYTSLYGPTVGDSIRLGDTNLFAQIEKDYAVYGEEATFGGGKSIRDGMAQNPRVTRDDVNVADLVISNAVII
DYDKVVKADIGIKNGYIFAIGNAGNPDIMDNVDIIIGSTTDIIAAEGKIVTAGGIDTHVHFINPEQAEVALESGITTHIG
GGTGASEGSKATTVTPGPWHIHRMLEAAEGLPINVGFTGKGQATNPTALIEQINAGAIGLKVHEDWGATPSALSHALDVA
DEFDVQIALHADTLNEAGFMEDTMAAVKDRVLHMYHTEGAGGGHAPDLIKSAAFSNILPSSTNPTLPYTHNTVDEHLDMV
MITHHLNAAIPEDIAFADSRIRKETIAAEDVLQDMGVFSMISSDSQAMGRVGEVITRTWQVAHRMKEQRGPLDGDFEHND
NNRIKRYIAKYTINPAITHGISEYVGSIEPGKLADIVLWDPIFFGVKPELVVKGGLINSAVNGDANGSIPTSEPMKYRKM
YGQYGGNLTSTSMTFVSKTAYENGINRALNLKRMVRPVKNIRQLSKADMKNNSATPKLDVDPQTYEVYVDGEKITSNAAT
ELPLTQRYFLF

Sequences:

>Translated_571_residues
MSFKMTQNQYTSLYGPTVGDSIRLGDTNLFAQIEKDYAVYGEEATFGGGKSIRDGMAQNPRVTRDDVNVADLVISNAVII
DYDKVVKADIGIKNGYIFAIGNAGNPDIMDNVDIIIGSTTDIIAAEGKIVTAGGIDTHVHFINPEQAEVALESGITTHIG
GGTGASEGSKATTVTPGPWHIHRMLEAAEGLPINVGFTGKGQATNPTALIEQINAGAIGLKVHEDWGATPSALSHALDVA
DEFDVQIALHADTLNEAGFMEDTMAAVKDRVLHMYHTEGAGGGHAPDLIKSAAFSNILPSSTNPTLPYTHNTVDEHLDMV
MITHHLNAAIPEDIAFADSRIRKETIAAEDVLQDMGVFSMISSDSQAMGRVGEVITRTWQVAHRMKEQRGPLDGDFEHND
NNRIKRYIAKYTINPAITHGISEYVGSIEPGKLADIVLWDPIFFGVKPELVVKGGLINSAVNGDANGSIPTSEPMKYRKM
YGQYGGNLTSTSMTFVSKTAYENGINRALNLKRMVRPVKNIRQLSKADMKNNSATPKLDVDPQTYEVYVDGEKITSNAAT
ELPLTQRYFLF
>Mature_570_residues
SFKMTQNQYTSLYGPTVGDSIRLGDTNLFAQIEKDYAVYGEEATFGGGKSIRDGMAQNPRVTRDDVNVADLVISNAVIID
YDKVVKADIGIKNGYIFAIGNAGNPDIMDNVDIIIGSTTDIIAAEGKIVTAGGIDTHVHFINPEQAEVALESGITTHIGG
GTGASEGSKATTVTPGPWHIHRMLEAAEGLPINVGFTGKGQATNPTALIEQINAGAIGLKVHEDWGATPSALSHALDVAD
EFDVQIALHADTLNEAGFMEDTMAAVKDRVLHMYHTEGAGGGHAPDLIKSAAFSNILPSSTNPTLPYTHNTVDEHLDMVM
ITHHLNAAIPEDIAFADSRIRKETIAAEDVLQDMGVFSMISSDSQAMGRVGEVITRTWQVAHRMKEQRGPLDGDFEHNDN
NRIKRYIAKYTINPAITHGISEYVGSIEPGKLADIVLWDPIFFGVKPELVVKGGLINSAVNGDANGSIPTSEPMKYRKMY
GQYGGNLTSTSMTFVSKTAYENGINRALNLKRMVRPVKNIRQLSKADMKNNSATPKLDVDPQTYEVYVDGEKITSNAATE
LPLTQRYFLF

Specific function: Unknown

COG id: COG0804

COG function: function code E; Urea amidohydrolase (urease) alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 urease domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): URE1_STAA1 (A7X5M3)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001442864.1
- ProteinModelPortal:   A7X5M3
- SMR:   A7X5M3
- STRING:   A7X5M3
- MEROPS:   M38.982
- EnsemblBacteria:   EBSTAT00000003866
- GeneID:   5561226
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_2274
- eggNOG:   COG0804
- GeneTree:   EBGT00050000025341
- HOGENOM:   HBG357507
- OMA:   TIHAFHT
- ProtClustDB:   PRK13207
- BioCyc:   SAUR418127:SAHV_2274-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01953
- InterPro:   IPR006680
- InterPro:   IPR011059
- InterPro:   IPR011612
- InterPro:   IPR005848
- InterPro:   IPR017951
- InterPro:   IPR017950
- PRINTS:   PR01752
- TIGRFAMs:   TIGR01792

Pfam domain/function: PF01979 Amidohydro_1; PF00449 Urease_alpha; SSF51338 Metalo_hydrolase

EC number: =3.5.1.5

Molecular weight: Translated: 61780; Mature: 61649

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS01120 UREASE_1; PS00145 UREASE_2; PS51368 UREASE_3

Important sites: ACT_SITE 324-324 BINDING 223-223

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFKMTQNQYTSLYGPTVGDSIRLGDTNLFAQIEKDYAVYGEEATFGGGKSIRDGMAQNP
CCCCCCCCCHHHCCCCCCCCEEEECCCCEEEEEECCCEEECCCCCCCCCCHHHCCCCCCC
RVTRDDVNVADLVISNAVIIDYDKVVKADIGIKNGYIFAIGNAGNPDIMDNVDIIIGSTT
CCCCCCCCHHHHHHCCEEEEEHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCEEEEECCC
DIIAAEGKIVTAGGIDTHVHFINPEQAEVALESGITTHIGGGTGASEGSKATTVTPGPWH
CEEEECCEEEEECCCEEEEEEECCCHHHHHHHCCCEEEECCCCCCCCCCCCEEECCCHHH
IHRMLEAAEGLPINVGFTGKGQATNPTALIEQINAGAIGLKVHEDWGATPSALSHALDVA
HHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHCC
DEFDVQIALHADTLNEAGFMEDTMAAVKDRVLHMYHTEGAGGGHAPDLIKSAAFSNILPS
CCCCEEEEEEECCCCCCCCHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHHCCCC
STNPTLPYTHNTVDEHLDMVMITHHLNAAIPEDIAFADSRIRKETIAAEDVLQDMGVFSM
CCCCCCCCCCCCHHHHHCEEEEEHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHH
ISSDSQAMGRVGEVITRTWQVAHRMKEQRGPLDGDFEHNDNNRIKRYIAKYTINPAITHG
HCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHH
ISEYVGSIEPGKLADIVLWDPIFFGVKPELVVKGGLINSAVNGDANGSIPTSEPMKYRKM
HHHHHCCCCCCCEEEEEEECCCCCCCCCCEEEECCCEECCCCCCCCCCCCCCCCHHHHHH
YGQYGGNLTSTSMTFVSKTAYENGINRALNLKRMVRPVKNIRQLSKADMKNNSATPKLDV
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEC
DPQTYEVYVDGEKITSNAATELPLTQRYFLF
CCCEEEEEECCCEECCCCCCCCCCCCHHCCC
>Mature Secondary Structure 
SFKMTQNQYTSLYGPTVGDSIRLGDTNLFAQIEKDYAVYGEEATFGGGKSIRDGMAQNP
CCCCCCCCHHHCCCCCCCCEEEECCCCEEEEEECCCEEECCCCCCCCCCHHHCCCCCCC
RVTRDDVNVADLVISNAVIIDYDKVVKADIGIKNGYIFAIGNAGNPDIMDNVDIIIGSTT
CCCCCCCCHHHHHHCCEEEEEHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCEEEEECCC
DIIAAEGKIVTAGGIDTHVHFINPEQAEVALESGITTHIGGGTGASEGSKATTVTPGPWH
CEEEECCEEEEECCCEEEEEEECCCHHHHHHHCCCEEEECCCCCCCCCCCCEEECCCHHH
IHRMLEAAEGLPINVGFTGKGQATNPTALIEQINAGAIGLKVHEDWGATPSALSHALDVA
HHHHHHHHCCCEEEEEECCCCCCCCHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHCC
DEFDVQIALHADTLNEAGFMEDTMAAVKDRVLHMYHTEGAGGGHAPDLIKSAAFSNILPS
CCCCEEEEEEECCCCCCCCHHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHHCCCC
STNPTLPYTHNTVDEHLDMVMITHHLNAAIPEDIAFADSRIRKETIAAEDVLQDMGVFSM
CCCCCCCCCCCCHHHHHCEEEEEHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHH
ISSDSQAMGRVGEVITRTWQVAHRMKEQRGPLDGDFEHNDNNRIKRYIAKYTINPAITHG
HCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHH
ISEYVGSIEPGKLADIVLWDPIFFGVKPELVVKGGLINSAVNGDANGSIPTSEPMKYRKM
HHHHHCCCCCCCEEEEEEECCCCCCCCCCEEEECCCEECCCCCCCCCCCCCCCCHHHHHH
YGQYGGNLTSTSMTFVSKTAYENGINRALNLKRMVRPVKNIRQLSKADMKNNSATPKLDV
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEC
DPQTYEVYVDGEKITSNAATELPLTQRYFLF
CCCEEEEEECCCEECCCCCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA