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The map label for this gene is qor [C]

Identifier: 57652203

GI number: 57652203

Start: 2258850

End: 2259851

Strand: Reverse

Name: qor [C]

Synonym: SACOL2177

Alternate gene names: 57652203

Gene position: 2259851-2258850 (Counterclockwise)

Preceding gene: 57652204

Following gene: 57652202

Centisome position: 80.44

GC content: 34.63

Gene sequence:

>1002_bases
ATGAAAATGATAGGATTTGAGAAGCCCTTTAAATTGGAAGAAGGAAATTTATTTAAAGTATACGAACAAAGAAAGCCAAC
GCCAGAAAACGATGATATCTTAGTCAAAGTAAATAGCATTAGTGTAAATCCTGTAGATACAAAGCAACGACAAATGGAAG
TCACTCAAGCACCTCGTGTACTTGGGTTTGATGCTATTGGTACTGTTGAAGCTATCGGACCAGACGTTACATTATTTAGT
CCGGGTGACGTTGTATTTTATGCTGGATCGCCAAATAGACAAGGATCAAATGCGACATATCAATTGGTGTCAGAAGCTAT
AGTTGCAAAAGCACCACACAACATAAGTGCTAATGAAGCGGTTAGTCTACCGCTAACTGGTATTACGGCATATGAAACGT
TTTTTGATACATTTAAAATTTCTACGAATCCTGCTGAAAACGAAGGGAAGTCTGTCTTAATCATTAATGGTGCCGGTGGT
GTAGGCAGTATAGCCACTCAAATTGCTAAACGGTATGGTTTAACTGTCATTACAACAGCATCACGACAAGAAACAACAGA
GTGGTGTGAAAAGATGGGCGCAGATATCGTATTGAATCATAAAGAGGATTTAGTGCGTCAATTTAAAGAAATTCCATTAG
TAGATTATATATTTTGCACCTATAATACAGACTTGTATTACAATACTATGATTGAACTGATAAAACCATTAGGGCATATT
ACGACTATCGTAGCTTTTAATGAAGATCAAGATTTAAATGCATTAAAATTAAAAAGTATAACATTTACACATGAATTTAT
GTTTGCGCGTCCAATTCATCGAACGCCTGATATGATTAAACAACATGAGTATTTAGAAGATATTACGAAAAATATAGAAT
CAGGGCATTACCAACCAACAACGACACAAGTTTTTGAAGGTTTATCACCTGAAAACTTATATCAAGCACATCAATTGTTG
GAAAAACAATCAATGATTGGAAAATTAGTAATTAATATATAG

Upstream 100 bases:

>100_bases
ATATATTCAAATGAAAAAGGAGTCATGATGCTGCGATATAAGCACACATGGCTTCTATTTTGTATAATAAGAAATAAGTT
CATAAATGAGGTGAAACGAT

Downstream 100 bases:

>100_bases
ATTAGTAAGTAAAGTCGCCTTATGCAGAAAATACTGTATAGGCGACTTATTTTTTGTGTCTAGCGACTATTGATTCTAAA
CGGAAATATGGCAACTTTGC

Product: alcohol dehydrogenase, zinc-containing

Products: aldehyde; ketone; NADH; H+

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MKMIGFEKPFKLEEGNLFKVYEQRKPTPENDDILVKVNSISVNPVDTKQRQMEVTQAPRVLGFDAIGTVEAIGPDVTLFS
PGDVVFYAGSPNRQGSNATYQLVSEAIVAKAPHNISANEAVSLPLTGITAYETFFDTFKISTNPAENEGKSVLIINGAGG
VGSIATQIAKRYGLTVITTASRQETTEWCEKMGADIVLNHKEDLVRQFKEIPLVDYIFCTYNTDLYYNTMIELIKPLGHI
TTIVAFNEDQDLNALKLKSITFTHEFMFARPIHRTPDMIKQHEYLEDITKNIESGHYQPTTTQVFEGLSPENLYQAHQLL
EKQSMIGKLVINI

Sequences:

>Translated_333_residues
MKMIGFEKPFKLEEGNLFKVYEQRKPTPENDDILVKVNSISVNPVDTKQRQMEVTQAPRVLGFDAIGTVEAIGPDVTLFS
PGDVVFYAGSPNRQGSNATYQLVSEAIVAKAPHNISANEAVSLPLTGITAYETFFDTFKISTNPAENEGKSVLIINGAGG
VGSIATQIAKRYGLTVITTASRQETTEWCEKMGADIVLNHKEDLVRQFKEIPLVDYIFCTYNTDLYYNTMIELIKPLGHI
TTIVAFNEDQDLNALKLKSITFTHEFMFARPIHRTPDMIKQHEYLEDITKNIESGHYQPTTTQVFEGLSPENLYQAHQLL
EKQSMIGKLVINI
>Mature_333_residues
MKMIGFEKPFKLEEGNLFKVYEQRKPTPENDDILVKVNSISVNPVDTKQRQMEVTQAPRVLGFDAIGTVEAIGPDVTLFS
PGDVVFYAGSPNRQGSNATYQLVSEAIVAKAPHNISANEAVSLPLTGITAYETFFDTFKISTNPAENEGKSVLIINGAGG
VGSIATQIAKRYGLTVITTASRQETTEWCEKMGADIVLNHKEDLVRQFKEIPLVDYIFCTYNTDLYYNTMIELIKPLGHI
TTIVAFNEDQDLNALKLKSITFTHEFMFARPIHRTPDMIKQHEYLEDITKNIESGHYQPTTTQVFEGLSPENLYQAHQLL
EKQSMIGKLVINI

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI47519420, Length=331, Percent_Identity=26.5861027190332, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI194239676, Length=180, Percent_Identity=32.2222222222222, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI194239674, Length=180, Percent_Identity=32.2222222222222, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI13236495, Length=180, Percent_Identity=32.2222222222222, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI22538446, Length=207, Percent_Identity=29.951690821256, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI22538444, Length=207, Percent_Identity=29.951690821256, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI24308257, Length=236, Percent_Identity=27.9661016949153, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI28557745, Length=184, Percent_Identity=30.4347826086957, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1790485, Length=202, Percent_Identity=32.6732673267327, Blast_Score=72, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71987554, Length=358, Percent_Identity=25.1396648044693, Blast_Score=81, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17507255, Length=326, Percent_Identity=24.8466257668712, Blast_Score=76, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6319520, Length=190, Percent_Identity=32.6315789473684, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR014182
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: 1.1.1.1

Molecular weight: Translated: 37270; Mature: 37270

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS01162 QOR_ZETA_CRYSTAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMIGFEKPFKLEEGNLFKVYEQRKPTPENDDILVKVNSISVNPVDTKQRQMEVTQAPRV
CCCCCCCCCCEECCCCEEEEEHHCCCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHCCCE
LGFDAIGTVEAIGPDVTLFSPGDVVFYAGSPNRQGSNATYQLVSEAIVAKAPHNISANEA
ECCCCCCCHHHCCCCEEEECCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCE
VSLPLTGITAYETFFDTFKISTNPAENEGKSVLIINGAGGVGSIATQIAKRYGLTVITTA
EECCCCCHHHHHHHHHHEEECCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCEEEEEC
SRQETTEWCEKMGADIVLNHKEDLVRQFKEIPLVDYIFCTYNTDLYYNTMIELIKPLGHI
CCHHHHHHHHHCCCCEEEECHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHE
TTIVAFNEDQDLNALKLKSITFTHEFMFARPIHRTPDMIKQHEYLEDITKNIESGHYQPT
EEEEEECCCCCCCEEEEEEEEEEHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
TTQVFEGLSPENLYQAHQLLEKQSMIGKLVINI
HHHHHCCCCHHHHHHHHHHHHHHHHHHEEEECC
>Mature Secondary Structure
MKMIGFEKPFKLEEGNLFKVYEQRKPTPENDDILVKVNSISVNPVDTKQRQMEVTQAPRV
CCCCCCCCCCEECCCCEEEEEHHCCCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHCCCE
LGFDAIGTVEAIGPDVTLFSPGDVVFYAGSPNRQGSNATYQLVSEAIVAKAPHNISANEA
ECCCCCCCHHHCCCCEEEECCCCEEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCE
VSLPLTGITAYETFFDTFKISTNPAENEGKSVLIINGAGGVGSIATQIAKRYGLTVITTA
EECCCCCHHHHHHHHHHEEECCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCEEEEEC
SRQETTEWCEKMGADIVLNHKEDLVRQFKEIPLVDYIFCTYNTDLYYNTMIELIKPLGHI
CCHHHHHHHHHCCCCEEEECHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHE
TTIVAFNEDQDLNALKLKSITFTHEFMFARPIHRTPDMIKQHEYLEDITKNIESGHYQPT
EEEEEECCCCCCCEEEEEEEEEEHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
TTQVFEGLSPENLYQAHQLLEKQSMIGKLVINI
HHHHHCCCCHHHHHHHHHHHHHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: alcohol; NAD+

Specific reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11418146 [H]