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The map label for this gene is yusP [H]

Identifier: 57652186

GI number: 57652186

Start: 2237711

End: 2239054

Strand: Reverse

Name: yusP [H]

Synonym: SACOL2159

Alternate gene names: 57652186

Gene position: 2239054-2237711 (Counterclockwise)

Preceding gene: 57652187

Following gene: 57652185

Centisome position: 79.7

GC content: 30.73

Gene sequence:

>1344_bases
ATGCGATTAAAGTCAATCATAACTGTTATAGCTTTAATATTAATTATGTTTATGTCAGCGATTGAATCATCTATTATTTC
GCTTGCATTACCTACAATTAAACAAGATTTAAATGCAGGAAATTTAATTTCATTAATTTTCACAGCGTATTTTATCGCAT
TAGTAATTGCCAATCCTATAGTGGGCGAATTACTTTCGAGATTTAAAATTATTTATGTGGCAATTGCAGGATTACTTTTA
TTTAGTATAGGTAGTTTTATGTGTGGTTTAAGTACTAATTTTACTATGCTAATTATATCACGCGTGATACAAGGTTTTGG
ATCAGGTGTATTGATGTCATTATCGCAAATTGTTCCAAAGTTAGCATTTGAAATTCCGTTACGATATAAAATTATGGGCA
TAGTTGGCAGTGTTTGGGGTATTTCGAGTATCATTGGGCCACTTCTAGGTGGTGGTATATTAGAATTTGCAACATGGCAT
TGGTTATTCTACATAAATATACCGATTGCGATCATTGCCATTATATTAGTTATATGGACATTTCATTTTCCAGAGGAAGA
AACAGTTGCTAAATCAAAATTTGATACTAAAGGGCTCACGCTATTTTATGTATTTATTGGATTGATTATGTTTGCTTTAT
TAAACCAACAGCTGTTACTTTTAAATTTCTTGAGTTTTATCTTAGCTATCGTTGTGGCAATGTGTTTATTTAAAGTAGAA
AAACATGTTTCTTCACCATTTTTACCTGTGGTTGAATTTAATCGTTCGATTACTTTAGTTTTTATAACTGACCTTCTAAC
AGCTATTTGTTTAATGGGATTCAATTTATATATTCCAGTCTACCTTCAAGAACAACTAGGATTATCTCCATTGCAAAGTG
GATTGGTTATTTTTCCTTTATCTGTAGCTTGGATTACATTGAATTTTAATTTACATCGAATTGAAGCAAAACTATCAAGG
AAAGTTATTTACTTACTATCATTTACATTGCTACTAGTAAGTAGTATTATCATTTCATTTGGTATTAAATTGCCGGTACT
TATAGCATTTGTGTTAATTTTGGCAGGATTAAGTTTTGGATATATTTATACGAAAGATAGTGTGATTGTCCAAGAGGAAA
CTAGCCCATTACAAATGAAGAAAATGATGTCATTTTATGGATTAACTAAAAATCTTGGGGCATCAATAGGTTCAACAATA
ATGGGATATCTTTATGCGATACAATCAGGAATCTTTGGTCCAAACTTACACAATGTGTTAAGTGCTGTTGCTGTAATTAG
CATTGGGCTTATTGTTTTATGGGTCGTATTTTTTAAAGAACAGTCATCTCAATCAAAAGAATAG

Upstream 100 bases:

>100_bases
AATTATCGTTAAGATTTGAAAGTCAAAAGTGTTTATACATATGAAAACCAATTATTTGTAAATAAAATCTTATAAATAAA
TATATAGAAGGAGGTATTTC

Downstream 100 bases:

>100_bases
AATTATGATTAAAATTGATGTAGTGTAATTAAAGTAAGAAATAATAAATTTCCTAGATACTAGATAAATCGTTCAATATT
TTATTAATAAGGAGGCCAAT

Product: drug transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MRLKSIITVIALILIMFMSAIESSIISLALPTIKQDLNAGNLISLIFTAYFIALVIANPIVGELLSRFKIIYVAIAGLLL
FSIGSFMCGLSTNFTMLIISRVIQGFGSGVLMSLSQIVPKLAFEIPLRYKIMGIVGSVWGISSIIGPLLGGGILEFATWH
WLFYINIPIAIIAIILVIWTFHFPEEETVAKSKFDTKGLTLFYVFIGLIMFALLNQQLLLLNFLSFILAIVVAMCLFKVE
KHVSSPFLPVVEFNRSITLVFITDLLTAICLMGFNLYIPVYLQEQLGLSPLQSGLVIFPLSVAWITLNFNLHRIEAKLSR
KVIYLLSFTLLLVSSIIISFGIKLPVLIAFVLILAGLSFGYIYTKDSVIVQEETSPLQMKKMMSFYGLTKNLGASIGSTI
MGYLYAIQSGIFGPNLHNVLSAVAVISIGLIVLWVVFFKEQSSQSKE

Sequences:

>Translated_447_residues
MRLKSIITVIALILIMFMSAIESSIISLALPTIKQDLNAGNLISLIFTAYFIALVIANPIVGELLSRFKIIYVAIAGLLL
FSIGSFMCGLSTNFTMLIISRVIQGFGSGVLMSLSQIVPKLAFEIPLRYKIMGIVGSVWGISSIIGPLLGGGILEFATWH
WLFYINIPIAIIAIILVIWTFHFPEEETVAKSKFDTKGLTLFYVFIGLIMFALLNQQLLLLNFLSFILAIVVAMCLFKVE
KHVSSPFLPVVEFNRSITLVFITDLLTAICLMGFNLYIPVYLQEQLGLSPLQSGLVIFPLSVAWITLNFNLHRIEAKLSR
KVIYLLSFTLLLVSSIIISFGIKLPVLIAFVLILAGLSFGYIYTKDSVIVQEETSPLQMKKMMSFYGLTKNLGASIGSTI
MGYLYAIQSGIFGPNLHNVLSAVAVISIGLIVLWVVFFKEQSSQSKE
>Mature_447_residues
MRLKSIITVIALILIMFMSAIESSIISLALPTIKQDLNAGNLISLIFTAYFIALVIANPIVGELLSRFKIIYVAIAGLLL
FSIGSFMCGLSTNFTMLIISRVIQGFGSGVLMSLSQIVPKLAFEIPLRYKIMGIVGSVWGISSIIGPLLGGGILEFATWH
WLFYINIPIAIIAIILVIWTFHFPEEETVAKSKFDTKGLTLFYVFIGLIMFALLNQQLLLLNFLSFILAIVVAMCLFKVE
KHVSSPFLPVVEFNRSITLVFITDLLTAICLMGFNLYIPVYLQEQLGLSPLQSGLVIFPLSVAWITLNFNLHRIEAKLSR
KVIYLLSFTLLLVSSIIISFGIKLPVLIAFVLILAGLSFGYIYTKDSVIVQEETSPLQMKKMMSFYGLTKNLGASIGSTI
MGYLYAIQSGIFGPNLHNVLSAVAVISIGLIVLWVVFFKEQSSQSKE

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. EmrB family [H]

Homologues:

Organism=Escherichia coli, GI87081983, Length=437, Percent_Identity=27.6887871853547, Blast_Score=124, Evalue=9e-30,
Organism=Escherichia coli, GI1790195, Length=409, Percent_Identity=22.9828850855746, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI1789042, Length=425, Percent_Identity=25.6470588235294, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1788710, Length=331, Percent_Identity=29.3051359516616, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI1788392, Length=414, Percent_Identity=23.1884057971014, Blast_Score=86, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6322958, Length=182, Percent_Identity=26.3736263736264, Blast_Score=76, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6323735, Length=306, Percent_Identity=25.1633986928105, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6321663, Length=149, Percent_Identity=28.1879194630872, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004638
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 49411; Mature: 49411

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLKSIITVIALILIMFMSAIESSIISLALPTIKQDLNAGNLISLIFTAYFIALVIANPI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCHH
VGELLSRFKIIYVAIAGLLLFSIGSFMCGLSTNFTMLIISRVIQGFGSGVLMSLSQIVPK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHH
LAFEIPLRYKIMGIVGSVWGISSIIGPLLGGGILEFATWHWLFYINIPIAIIAIILVIWT
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEEHHHHHHHHHHHHHHH
FHFPEEETVAKSKFDTKGLTLFYVFIGLIMFALLNQQLLLLNFLSFILAIVVAMCLFKVE
CCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
KHVSSPFLPVVEFNRSITLVFITDLLTAICLMGFNLYIPVYLQEQLGLSPLQSGLVIFPL
HHHCCCCCHHEECCCCEEEEEHHHHHHHHHHCCCHHHHHEEEHHHCCCCHHHCCCEEEEE
SVAWITLNFNLHRIEAKLSRKVIYLLSFTLLLVSSIIISFGIKLPVLIAFVLILAGLSFG
EEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCC
YIYTKDSVIVQEETSPLQMKKMMSFYGLTKNLGASIGSTIMGYLYAIQSGIFGPNLHNVL
EEEECCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
SAVAVISIGLIVLWVVFFKEQSSQSKE
HHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MRLKSIITVIALILIMFMSAIESSIISLALPTIKQDLNAGNLISLIFTAYFIALVIANPI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCHH
VGELLSRFKIIYVAIAGLLLFSIGSFMCGLSTNFTMLIISRVIQGFGSGVLMSLSQIVPK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHH
LAFEIPLRYKIMGIVGSVWGISSIIGPLLGGGILEFATWHWLFYINIPIAIIAIILVIWT
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEEHHHHHHHHHHHHHHH
FHFPEEETVAKSKFDTKGLTLFYVFIGLIMFALLNQQLLLLNFLSFILAIVVAMCLFKVE
CCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
KHVSSPFLPVVEFNRSITLVFITDLLTAICLMGFNLYIPVYLQEQLGLSPLQSGLVIFPL
HHHCCCCCHHEECCCCEEEEEHHHHHHHHHHCCCHHHHHEEEHHHCCCCHHHCCCEEEEE
SVAWITLNFNLHRIEAKLSRKVIYLLSFTLLLVSSIIISFGIKLPVLIAFVLILAGLSFG
EEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCC
YIYTKDSVIVQEETSPLQMKKMMSFYGLTKNLGASIGSTIMGYLYAIQSGIFGPNLHNVL
EEEECCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
SAVAVISIGLIVLWVVFFKEQSSQSKE
HHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]