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The map label for this gene is mtlD [H]

Identifier: 57652177

GI number: 57652177

Start: 2212964

End: 2214070

Strand: Direct

Name: mtlD [H]

Synonym: SACOL2149

Alternate gene names: 57652177

Gene position: 2212964-2214070 (Clockwise)

Preceding gene: 57652176

Following gene: 57652190

Centisome position: 78.77

GC content: 32.88

Gene sequence:

>1107_bases
ATGAAAGCAGTTCACTTTGGTGCTGGTAACATAGGTCGTGGTTTCATTGGTTATATTCTTGCAGACAACAATGTTAAAGT
AACATTTGCAGACGTCAATGAAGAAATCATTAATGCTTTAGCTCATGATCATCAATACGATGTTATTTTAGCTGATGAGT
CTAAAACAACGACGCGCGTGAATAATGTTGATGCAATTAATTCAATGCAACCTTCTGAAGCGTTGAAACAAGCAATTCTA
GAAGCTGATATTATTACAACAGCTGTTGGTGTTAACATACTACCTATTATTGCTAAATCTTTTGCGCCTTTCTTAAAAGA
AAAAACAAACCATGTTAATATTGTTGCTTGTGAGAATGCTATTATGGCAACTGATACATTGAAAAAAGCAGTACTTGATA
TTACTGGCCCTCTTGGTAACAATATTCATTTTGCTAACTCAGCAGTTGATAGAATTGTACCATTACAAAAGAATGAAAAT
ATATTAGACGTTATGGTTGAGCCATTTTACGAATGGGTTGTTGAAAAAGATGCATGGTATGGTCCAGAACTAAACCATAT
TAAATATGTTGATGATTTAACACCATATATTGAGCGTAAATTATTAACTGTGAATACAGGACATGCATATTTAGCGTATG
CTGGTAAATTTGCAGGTAAAGCTACAGTTTTAGATGCAGTTGAAGATAGTTCAATTGAAGCTGGCTTACGCCGTGTTTTA
GCTGAAACTAGTCAATATATTACTAATGAATTTGATTTTACTGAAGCGGAACAAGCTGCTTATGTTGAAAAAATAATAGA
TCGTTTCAACAATTCTTATTTATCTGATGAAGTAACACGTGTCGGACGAGGTACATTACGTAAAATTGGCCCTAAAGATA
GAATTATAAAACCATTAACATATCTTTATAATAAAGATTTAGAACGCACTGGTTTATTAAATACAGCTGCATTGTTATTG
AAGTATGATGATACAGCAGACCAAGAAACTGTTGAGAAAAATAATTACATTAAAGAACACGGTTTAAAAGCGTTTTTAAG
TGAATATGCTAAAGTTGACGATGGCTTAGCCGATGAAATAATTGAAGCGTACAATTCACTTTCATAA

Upstream 100 bases:

>100_bases
AAATTGCAATTACATTTAGCGAAGAAGAAAATGTGGATCGTATCGTTCAAGCAAAATCTGCAGAAGAAATTAAACAAGTA
TTCGAGGAGGCAGATGCATA

Downstream 100 bases:

>100_bases
TTTATTGAGCTTTGTTTGAAACAAGAAGTTTCCAACGTTATTCGTTAACAATCAGTAATAATGTAGTAGTTCCCTTGAAT
TAACAATATTAAATTTCTGA

Product: mannitol-1-phosphate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MKAVHFGAGNIGRGFIGYILADNNVKVTFADVNEEIINALAHDHQYDVILADESKTTTRVNNVDAINSMQPSEALKQAIL
EADIITTAVGVNILPIIAKSFAPFLKEKTNHVNIVACENAIMATDTLKKAVLDITGPLGNNIHFANSAVDRIVPLQKNEN
ILDVMVEPFYEWVVEKDAWYGPELNHIKYVDDLTPYIERKLLTVNTGHAYLAYAGKFAGKATVLDAVEDSSIEAGLRRVL
AETSQYITNEFDFTEAEQAAYVEKIIDRFNNSYLSDEVTRVGRGTLRKIGPKDRIIKPLTYLYNKDLERTGLLNTAALLL
KYDDTADQETVEKNNYIKEHGLKAFLSEYAKVDDGLADEIIEAYNSLS

Sequences:

>Translated_368_residues
MKAVHFGAGNIGRGFIGYILADNNVKVTFADVNEEIINALAHDHQYDVILADESKTTTRVNNVDAINSMQPSEALKQAIL
EADIITTAVGVNILPIIAKSFAPFLKEKTNHVNIVACENAIMATDTLKKAVLDITGPLGNNIHFANSAVDRIVPLQKNEN
ILDVMVEPFYEWVVEKDAWYGPELNHIKYVDDLTPYIERKLLTVNTGHAYLAYAGKFAGKATVLDAVEDSSIEAGLRRVL
AETSQYITNEFDFTEAEQAAYVEKIIDRFNNSYLSDEVTRVGRGTLRKIGPKDRIIKPLTYLYNKDLERTGLLNTAALLL
KYDDTADQETVEKNNYIKEHGLKAFLSEYAKVDDGLADEIIEAYNSLS
>Mature_368_residues
MKAVHFGAGNIGRGFIGYILADNNVKVTFADVNEEIINALAHDHQYDVILADESKTTTRVNNVDAINSMQPSEALKQAIL
EADIITTAVGVNILPIIAKSFAPFLKEKTNHVNIVACENAIMATDTLKKAVLDITGPLGNNIHFANSAVDRIVPLQKNEN
ILDVMVEPFYEWVVEKDAWYGPELNHIKYVDDLTPYIERKLLTVNTGHAYLAYAGKFAGKATVLDAVEDSSIEAGLRRVL
AETSQYITNEFDFTEAEQAAYVEKIIDRFNNSYLSDEVTRVGRGTLRKIGPKDRIIKPLTYLYNKDLERTGLLNTAALLL
KYDDTADQETVEKNNYIKEHGLKAFLSEYAKVDDGLADEIIEAYNSLS

Specific function: Unknown

COG id: COG0246

COG function: function code G; Mannitol-1-phosphate/altronate dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannitol dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1790028, Length=388, Percent_Identity=36.8556701030928, Blast_Score=244, Evalue=9e-66,
Organism=Escherichia coli, GI1788497, Length=206, Percent_Identity=26.6990291262136, Blast_Score=78, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR023028
- InterPro:   IPR000669
- InterPro:   IPR013118
- InterPro:   IPR023027
- InterPro:   IPR013131
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01232 Mannitol_dh; PF08125 Mannitol_dh_C [H]

EC number: =1.1.1.17 [H]

Molecular weight: Translated: 40952; Mature: 40952

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS00974 MANNITOL_DHGENASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAVHFGAGNIGRGFIGYILADNNVKVTFADVNEEIINALAHDHQYDVILADESKTTTRV
CCEEEECCCCCCCCEEEEEEECCCEEEEEECCCHHHHHHHHCCCCEEEEEECCCCCCEEC
NNVDAINSMQPSEALKQAILEADIITTAVGVNILPIIAKSFAPFLKEKTNHVNIVACENA
CCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC
IMATDTLKKAVLDITGPLGNNIHFANSAVDRIVPLQKNENILDVMVEPFYEWVVEKDAWY
HHHHHHHHHHHHHHCCCCCCCEEECCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCC
GPELNHIKYVDDLTPYIERKLLTVNTGHAYLAYAGKFAGKATVLDAVEDSSIEAGLRRVL
CCCCCCEEEHHHHHHHHCCEEEEEECCCEEEEECCCCCCCHHHHHHHCCHHHHHHHHHHH
AETSQYITNEFDFTEAEQAAYVEKIIDRFNNSYLSDEVTRVGRGTLRKIGPKDRIIKPLT
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHCCCHHHHHHHHH
YLYNKDLERTGLLNTAALLLKYDDTADQETVEKNNYIKEHGLKAFLSEYAKVDDGLADEI
HHHCCCCHHHCCHHHEEEEEEECCCCCHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHH
IEAYNSLS
HHHHHCCC
>Mature Secondary Structure
MKAVHFGAGNIGRGFIGYILADNNVKVTFADVNEEIINALAHDHQYDVILADESKTTTRV
CCEEEECCCCCCCCEEEEEEECCCEEEEEECCCHHHHHHHHCCCCEEEEEECCCCCCEEC
NNVDAINSMQPSEALKQAILEADIITTAVGVNILPIIAKSFAPFLKEKTNHVNIVACENA
CCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC
IMATDTLKKAVLDITGPLGNNIHFANSAVDRIVPLQKNENILDVMVEPFYEWVVEKDAWY
HHHHHHHHHHHHHHCCCCCCCEEECCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCC
GPELNHIKYVDDLTPYIERKLLTVNTGHAYLAYAGKFAGKATVLDAVEDSSIEAGLRRVL
CCCCCCEEEHHHHHHHHCCEEEEEECCCEEEEECCCCCCCHHHHHHHCCHHHHHHHHHHH
AETSQYITNEFDFTEAEQAAYVEKIIDRFNNSYLSDEVTRVGRGTLRKIGPKDRIIKPLT
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHCCCHHHHHHHHH
YLYNKDLERTGLLNTAALLLKYDDTADQETVEKNNYIKEHGLKAFLSEYAKVDDGLADEI
HHHCCCCHHHCCHHHEEEEEEECCCCCHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHH
IEAYNSLS
HHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA