Click here to switch to the map view.

The map label for this gene is murC [H]

Identifier: 57652038

GI number: 57652038

Start: 1835781

End: 1837094

Strand: Reverse

Name: murC [H]

Synonym: SACOL1790

Alternate gene names: 57652038

Gene position: 1837094-1835781 (Counterclockwise)

Preceding gene: 57652039

Following gene: 57652037

Centisome position: 65.39

GC content: 31.28

Gene sequence:

>1314_bases
ATGACACACTATCATTTTGTCGGAATTAAAGGTTCTGGCATGAGTTCATTAGCACAAATCATGCATGATTTAGGACATGA
AGTTCAAGGATCGGATATTGAGAACTACGTATTTACAGAAGTTGCTCTTAGAAATAAGGGGATAAAAATATTACCATTTG
ATGCTAATAACATAAAAGAAGATATGGTAGTTATACAAGGTAATGCATTCGCGAGTAGCCATGAAGAAATAGTACGTGCA
CATCAATTGAAATTAGATGTTGTAAGTTATAATGATTTTTTAGGACAGATTATTGATCAATATACTTCAGTAGCTGTAAC
TGGTGCACATGGTAAAACTTCTACAACAGGTTTATTATCACATGTTATGAATGGTGATAAAAAGACTTCATTTTTAATTG
GTGATGGCACAGGTATGGGATTGCCTGAAAGTGATTATTTCGCTTTTGAGGCATGTGAATATAGACGTCACTTTTTAAGT
TATAAACCTGATTACGCAATTATGACAAATATTGATTTCGATCATCCTGATTATTTTAAAGATATTAATGATGTTTTTGA
TGCATTCCAAGAAATGGCACATAATGTTAAAAAAGGTATTATTGCTTGGGGTGATGATGAACATCTACGTAAAATTGAAG
CAGATGTTCCAATTTATTATTATGGATTTAAAGATTCGGATGACATTTATGCTCAAAATATTCAAATTACGGATAAAGGT
ACTGCTTTTGATGTGTATGTGGATGGTGAGTTTTATGATCACTTCCTGTCTCCACAATATGGTGACCATACAGTTTTAAA
TGCATTAGCTGTAATTGCGATTAGTTATTTAGAGAAGCTAGATGTTACAAATATTAAAGAAGCATTAGAAACGTTTGGTG
GTGTTAAACGTCGTTTCAATGAAACTACAATTGCAAATCAAGTTATTGTAGATGATTATGCACACCATCCAAGAGAAATT
AGTGCTACAATTGAAACAGCACGAAAGAAATATCCACATAAAGAAGTTGTTGCAGTATTTCAACCACACACTTTCTCTAG
AACACAGGCATTTTTAAATGAATTTGCAGAAAGTTTAAGTAAAGCAGATCGTGTATTCTTATGTGAAATTTTTGGATCAA
TTAGAGAAAATACTGGCGCATTAACGATACAAGATTTAATTGATAAAATTGAAGGTGCATCGTTAATTAATGAAGATTCT
ATTAATGTATTAGAACAATTTGATAATGCTGTTATTTTATTTATGGGTGCAGGTGATATTCAAAAATTACAAAATGCATA
TTTAGATAAATTAGGCATGAAAAATGCGTTTTAA

Upstream 100 bases:

>100_bases
TCGGTTATGTTTCGAGTGCTAATGGTTCAAAACCAAGGGATGTTTATGTTACGGAAGCAGATTTAAATAAAGAATAATTA
TGAGTAAGGAGTTTTATATA

Downstream 100 bases:

>100_bases
TATGTTTATAATAGAGTAGTATGGGTATTTATTATTAATGACATTATTACATGTTAATTAGGAGGCGTTTTTAATGGATT
GGATTTTACCAATTGCTGGA

Product: UDP-N-acetylmuramate--L-alanine ligase

Products: NA

Alternate protein names: UDP-N-acetylmuramoyl-L-alanine synthetase [H]

Number of amino acids: Translated: 437; Mature: 436

Protein sequence:

>437_residues
MTHYHFVGIKGSGMSSLAQIMHDLGHEVQGSDIENYVFTEVALRNKGIKILPFDANNIKEDMVVIQGNAFASSHEEIVRA
HQLKLDVVSYNDFLGQIIDQYTSVAVTGAHGKTSTTGLLSHVMNGDKKTSFLIGDGTGMGLPESDYFAFEACEYRRHFLS
YKPDYAIMTNIDFDHPDYFKDINDVFDAFQEMAHNVKKGIIAWGDDEHLRKIEADVPIYYYGFKDSDDIYAQNIQITDKG
TAFDVYVDGEFYDHFLSPQYGDHTVLNALAVIAISYLEKLDVTNIKEALETFGGVKRRFNETTIANQVIVDDYAHHPREI
SATIETARKKYPHKEVVAVFQPHTFSRTQAFLNEFAESLSKADRVFLCEIFGSIRENTGALTIQDLIDKIEGASLINEDS
INVLEQFDNAVILFMGAGDIQKLQNAYLDKLGMKNAF

Sequences:

>Translated_437_residues
MTHYHFVGIKGSGMSSLAQIMHDLGHEVQGSDIENYVFTEVALRNKGIKILPFDANNIKEDMVVIQGNAFASSHEEIVRA
HQLKLDVVSYNDFLGQIIDQYTSVAVTGAHGKTSTTGLLSHVMNGDKKTSFLIGDGTGMGLPESDYFAFEACEYRRHFLS
YKPDYAIMTNIDFDHPDYFKDINDVFDAFQEMAHNVKKGIIAWGDDEHLRKIEADVPIYYYGFKDSDDIYAQNIQITDKG
TAFDVYVDGEFYDHFLSPQYGDHTVLNALAVIAISYLEKLDVTNIKEALETFGGVKRRFNETTIANQVIVDDYAHHPREI
SATIETARKKYPHKEVVAVFQPHTFSRTQAFLNEFAESLSKADRVFLCEIFGSIRENTGALTIQDLIDKIEGASLINEDS
INVLEQFDNAVILFMGAGDIQKLQNAYLDKLGMKNAF
>Mature_436_residues
THYHFVGIKGSGMSSLAQIMHDLGHEVQGSDIENYVFTEVALRNKGIKILPFDANNIKEDMVVIQGNAFASSHEEIVRAH
QLKLDVVSYNDFLGQIIDQYTSVAVTGAHGKTSTTGLLSHVMNGDKKTSFLIGDGTGMGLPESDYFAFEACEYRRHFLSY
KPDYAIMTNIDFDHPDYFKDINDVFDAFQEMAHNVKKGIIAWGDDEHLRKIEADVPIYYYGFKDSDDIYAQNIQITDKGT
AFDVYVDGEFYDHFLSPQYGDHTVLNALAVIAISYLEKLDVTNIKEALETFGGVKRRFNETTIANQVIVDDYAHHPREIS
ATIETARKKYPHKEVVAVFQPHTFSRTQAFLNEFAESLSKADRVFLCEIFGSIRENTGALTIQDLIDKIEGASLINEDSI
NVLEQFDNAVILFMGAGDIQKLQNAYLDKLGMKNAF

Specific function: Cell wall formation [H]

COG id: COG0773

COG function: function code M; UDP-N-acetylmuramate-alanine ligase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MurCDEF family [H]

Homologues:

Organism=Escherichia coli, GI1790680, Length=387, Percent_Identity=29.4573643410853, Blast_Score=144, Evalue=8e-36,
Organism=Escherichia coli, GI1786279, Length=456, Percent_Identity=30.0438596491228, Blast_Score=144, Evalue=8e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004101
- InterPro:   IPR013221
- InterPro:   IPR000713
- InterPro:   IPR016040
- InterPro:   IPR005758 [H]

Pfam domain/function: PF01225 Mur_ligase; PF02875 Mur_ligase_C; PF08245 Mur_ligase_M [H]

EC number: =6.3.2.8 [H]

Molecular weight: Translated: 49189; Mature: 49058

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHYHFVGIKGSGMSSLAQIMHDLGHEVQGSDIENYVFTEVALRNKGIKILPFDANNIKE
CCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCC
DMVVIQGNAFASSHEEIVRAHQLKLDVVSYNDFLGQIIDQYTSVAVTGAHGKTSTTGLLS
CEEEEECCCCCCHHHHHHHHHHHEEEEECHHHHHHHHHHHHHHEEEECCCCCCHHHHHHH
HVMNGDKKTSFLIGDGTGMGLPESDYFAFEACEYRRHFLSYKPDYAIMTNIDFDHPDYFK
HHHCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHH
DINDVFDAFQEMAHNVKKGIIAWGDDEHLRKIEADVPIYYYGFKDSDDIYAQNIQITDKG
HHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHCCCCEEEECCCCCCCEEEEEEEEECCC
TAFDVYVDGEFYDHFLSPQYGDHTVLNALAVIAISYLEKLDVTNIKEALETFGGVKRRFN
CEEEEEECCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHC
ETTIANQVIVDDYAHHPREISATIETARKKYPHKEVVAVFQPHTFSRTQAFLNEFAESLS
HHHHHHHHEEHHHCCCCHHHHHHHHHHHHHCCCHHEEEEECCCCHHHHHHHHHHHHHHHH
KADRVFLCEIFGSIRENTGALTIQDLIDKIEGASLINEDSINVLEQFDNAVILFMGAGDI
HHCCEEHHHHHHHHHCCCCCEEHHHHHHHHCCCCCCCCCHHHHHHHCCCEEEEEECCCHH
QKLQNAYLDKLGMKNAF
HHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
THYHFVGIKGSGMSSLAQIMHDLGHEVQGSDIENYVFTEVALRNKGIKILPFDANNIKE
CCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCCC
DMVVIQGNAFASSHEEIVRAHQLKLDVVSYNDFLGQIIDQYTSVAVTGAHGKTSTTGLLS
CEEEEECCCCCCHHHHHHHHHHHEEEEECHHHHHHHHHHHHHHEEEECCCCCCHHHHHHH
HVMNGDKKTSFLIGDGTGMGLPESDYFAFEACEYRRHFLSYKPDYAIMTNIDFDHPDYFK
HHHCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHH
DINDVFDAFQEMAHNVKKGIIAWGDDEHLRKIEADVPIYYYGFKDSDDIYAQNIQITDKG
HHHHHHHHHHHHHHHHHCCCEEECCHHHHHHHHCCCCEEEECCCCCCCEEEEEEEEECCC
TAFDVYVDGEFYDHFLSPQYGDHTVLNALAVIAISYLEKLDVTNIKEALETFGGVKRRFN
CEEEEEECCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHC
ETTIANQVIVDDYAHHPREISATIETARKKYPHKEVVAVFQPHTFSRTQAFLNEFAESLS
HHHHHHHHEEHHHCCCCHHHHHHHHHHHHHCCCHHEEEEECCCCHHHHHHHHHHHHHHHH
KADRVFLCEIFGSIRENTGALTIQDLIDKIEGASLINEDSINVLEQFDNAVILFMGAGDI
HHCCEEHHHHHHHHHCCCCCEEHHHHHHHHCCCCCCCCCHHHHHHHCCCEEEEEECCCHH
QKLQNAYLDKLGMKNAF
HHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA