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The map label for this gene is entA [H]

Identifier: 57651993

GI number: 57651993

Start: 1685330

End: 1686034

Strand: Reverse

Name: entA [H]

Synonym: SACOL1657

Alternate gene names: 57651993

Gene position: 1686034-1685330 (Counterclockwise)

Preceding gene: 57651994

Following gene: 57651991

Centisome position: 60.01

GC content: 28.79

Gene sequence:

>705_bases
TTGTTAGAAGGAATTTTTACAAATTCAGCGAGTGCAATCGAATATTCAGACTTACATCATAAAAGTAAGTTTGATTCAAA
GCGTCTAAGTAATGCTAAGATGTCATTCATCAATCCAACTCAGCTTGAAAATAAAAACACAAACGATAGACTGTTGAAGC
ATGATTTGTTATTTCATGACATGTTCGTAAATGATGATTGGAAAAAGGATTTTAAAGTTGAATTTGAAAATGAGGCACTT
TCAAAGAAATTTATAAATAAGGATATCGATATATTTGCTGGAAATTATGGATACGGATGTCATGGGGGAGCAACCAATAA
AACGCAATGTAGTTATGGTGGTGTTACTTTAAGTGACAATAATAAATACGATGATTATAAGAATATACCTTGTAATTTAT
GGATTGACGGACATCAAACAGAAATAGAACTAACTGCAGTAAAAACGAAAAAGAAAATTGTTACTATTCAAGAATTAGAG
GTTCAATTAAGAAATTATTTGAATGAGAAGTATAAGTTGTACGAACAAGGTGGCGACATTGTTAAAGGGTATGTTAAATA
TTATAATGATGATGAACAAAATGTAGAATATGATTTTTATAATTTAAATGGTGAGTATGGTCGTGAGGTATTAAAAATGT
ATGCTGATAATAAAACTATCAATAGTGACAAATTGCATTTAGATATCTATTTATTCAAATCATAA

Upstream 100 bases:

>100_bases
AGCGGTTCTTTATCATTTATGTCTCGCTCTCAAATGTAAATTAATAATTGTTTTGGGGGAGTTTGAAGTTAAATATTTAA
CAGGATTTATTTTAATATTA

Downstream 100 bases:

>100_bases
TTTAATTAAGTTAATCATTAATAATCTTTGACAGTGAAATATAAAGTACCTGTCATTATGTTGTTACAAATAAAAACAGC
AGTAAGGATGCTAACACTTA

Product: enterotoxin type A

Products: NA

Alternate protein names: SEA [H]

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MLEGIFTNSASAIEYSDLHHKSKFDSKRLSNAKMSFINPTQLENKNTNDRLLKHDLLFHDMFVNDDWKKDFKVEFENEAL
SKKFINKDIDIFAGNYGYGCHGGATNKTQCSYGGVTLSDNNKYDDYKNIPCNLWIDGHQTEIELTAVKTKKKIVTIQELE
VQLRNYLNEKYKLYEQGGDIVKGYVKYYNDDEQNVEYDFYNLNGEYGREVLKMYADNKTINSDKLHLDIYLFKS

Sequences:

>Translated_234_residues
MLEGIFTNSASAIEYSDLHHKSKFDSKRLSNAKMSFINPTQLENKNTNDRLLKHDLLFHDMFVNDDWKKDFKVEFENEAL
SKKFINKDIDIFAGNYGYGCHGGATNKTQCSYGGVTLSDNNKYDDYKNIPCNLWIDGHQTEIELTAVKTKKKIVTIQELE
VQLRNYLNEKYKLYEQGGDIVKGYVKYYNDDEQNVEYDFYNLNGEYGREVLKMYADNKTINSDKLHLDIYLFKS
>Mature_234_residues
MLEGIFTNSASAIEYSDLHHKSKFDSKRLSNAKMSFINPTQLENKNTNDRLLKHDLLFHDMFVNDDWKKDFKVEFENEAL
SKKFINKDIDIFAGNYGYGCHGGATNKTQCSYGGVTLSDNNKYDDYKNIPCNLWIDGHQTEIELTAVKTKKKIVTIQELE
VQLRNYLNEKYKLYEQGGDIVKGYVKYYNDDEQNVEYDFYNLNGEYGREVLKMYADNKTINSDKLHLDIYLFKS

Specific function: Staphylococcal enterotoxins cause the intoxication staphylococcal food poisoning syndrome. The illness is characterized by high fever, hypotension, diarrhea, shock, and in some cases death [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the staphylococcal/streptococcal toxin family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008992
- InterPro:   IPR006126
- InterPro:   IPR006173
- InterPro:   IPR016091
- InterPro:   IPR013307
- InterPro:   IPR006123
- InterPro:   IPR006177 [H]

Pfam domain/function: PF02876 Stap_Strp_tox_C; PF01123 Stap_Strp_toxin [H]

EC number: NA

Molecular weight: Translated: 27338; Mature: 27338

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: PS00277 STAPH_STREP_TOXIN_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEGIFTNSASAIEYSDLHHKSKFDSKRLSNAKMSFINPTQLENKNTNDRLLKHDLLFHD
CCCCEECCCCCEEEHHHHHHHHHCCHHHHCCCEEEECCCHHCCCCCCCHHHHHHHHHHHH
MFVNDDWKKDFKVEFENEALSKKFINKDIDIFAGNYGYGCHGGATNKTQCSYGGVTLSDN
EECCCCCCCCEEEEECCHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCEECCCCEEECCC
NKYDDYKNIPCNLWIDGHQTEIELTAVKTKKKIVTIQELEVQLRNYLNEKYKLYEQGGDI
CCCCCCCCCCEEEEECCCCEEEEEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHCCCHH
VKGYVKYYNDDEQNVEYDFYNLNGEYGREVLKMYADNKTINSDKLHLDIYLFKS
HHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCCCCCEEEEEEEEECC
>Mature Secondary Structure
MLEGIFTNSASAIEYSDLHHKSKFDSKRLSNAKMSFINPTQLENKNTNDRLLKHDLLFHD
CCCCEECCCCCEEEHHHHHHHHHCCHHHHCCCEEEECCCHHCCCCCCCHHHHHHHHHHHH
MFVNDDWKKDFKVEFENEALSKKFINKDIDIFAGNYGYGCHGGATNKTQCSYGGVTLSDN
EECCCCCCCCEEEEECCHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCEECCCCEEECCC
NKYDDYKNIPCNLWIDGHQTEIELTAVKTKKKIVTIQELEVQLRNYLNEKYKLYEQGGDI
CCCCCCCCCCEEEEECCCCEEEEEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHCCCHH
VKGYVKYYNDDEQNVEYDFYNLNGEYGREVLKMYADNKTINSDKLHLDIYLFKS
HHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCCCCCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3335483; 3584106; 7628431; 8943278; 7552730; 9191070 [H]