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The map label for this gene is aroK [H]

Identifier: 57651932

GI number: 57651932

Start: 1630028

End: 1630552

Strand: Reverse

Name: aroK [H]

Synonym: SACOL1596

Alternate gene names: 57651932

Gene position: 1630552-1630028 (Counterclockwise)

Preceding gene: 57651933

Following gene: 57651931

Centisome position: 58.04

GC content: 28.38

Gene sequence:

>525_bases
ATGAATCATGATAAATCACCAATAATTTTAATTGGTTTCATGGGTACCGGTAAATCTACGATTGGTAAATACGTTGCAGA
TGAGCAAAATTTATCATTTATTGATATAGATTCATATATCGAAGAGAAGTATAAGTTAACAATACCAGAAATATTTTGTA
AACATGGTGAACAATATTTCAGGAATTTAGAGTTCACATGTTTGCAAGAATGTATTAACACTGCAGATATAATTGCTACT
GGTGGTGGTATTATTGAGAGTGAAGAGGCATTTAATTTTTTGAAAAATCAAAAAAACATTATTTGGTTAGATTGTAATAT
TGATATTATATATAGTCGAATCAATGATGACCCACATCGACCTAATGCAAATAATAAGACAATCAAGCAGTTAAATGACT
TGTATTGCTCGCGGAATTTAAGATATAATGAAATCGCATTCAAGAAATTTGATAGTCATTTGCTATCAATTTCAGAAATA
TATTATGAATTGCTAAATTTAATAAAAGCGAGTGATCAGTATTAG

Upstream 100 bases:

>100_bases
TTTTATATCAGTCAATATAGTTTAAAATTAAAGACATTATATAATATTGAAACTGACTATAACTATAAGATTGTTTTGTT
ATTGAAAGAAGGGAAAACGC

Downstream 100 bases:

>100_bases
AGAGAATAGAGCGTTAAGACTCTATCGCCGAAGGTGCAAGTAATTTATTACGAAACTCTCAGGCAAAAGGATAATACTGT
AACGCGTTCCTGAATTGGTG

Product: shikimate kinase

Products: NA

Alternate protein names: SK [H]

Number of amino acids: Translated: 174; Mature: 174

Protein sequence:

>174_residues
MNHDKSPIILIGFMGTGKSTIGKYVADEQNLSFIDIDSYIEEKYKLTIPEIFCKHGEQYFRNLEFTCLQECINTADIIAT
GGGIIESEEAFNFLKNQKNIIWLDCNIDIIYSRINDDPHRPNANNKTIKQLNDLYCSRNLRYNEIAFKKFDSHLLSISEI
YYELLNLIKASDQY

Sequences:

>Translated_174_residues
MNHDKSPIILIGFMGTGKSTIGKYVADEQNLSFIDIDSYIEEKYKLTIPEIFCKHGEQYFRNLEFTCLQECINTADIIAT
GGGIIESEEAFNFLKNQKNIIWLDCNIDIIYSRINDDPHRPNANNKTIKQLNDLYCSRNLRYNEIAFKKFDSHLLSISEI
YYELLNLIKASDQY
>Mature_174_residues
MNHDKSPIILIGFMGTGKSTIGKYVADEQNLSFIDIDSYIEEKYKLTIPEIFCKHGEQYFRNLEFTCLQECINTADIIAT
GGGIIESEEAFNFLKNQKNIIWLDCNIDIIYSRINDDPHRPNANNKTIKQLNDLYCSRNLRYNEIAFKKFDSHLLSISEI
YYELLNLIKASDQY

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate [H]

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786587, Length=150, Percent_Identity=29.3333333333333, Blast_Score=85, Evalue=2e-18,
Organism=Escherichia coli, GI87082255, Length=146, Percent_Identity=34.9315068493151, Blast_Score=84, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR023000 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.71 [H]

Molecular weight: Translated: 20222; Mature: 20222

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS01128 SHIKIMATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHDKSPIILIGFMGTGKSTIGKYVADEQNLSFIDIDSYIEEKYKLTIPEIFCKHGEQYF
CCCCCCCEEEEEECCCCHHHHHHHHCCCCCCEEEEHHHHHHHHHEECHHHHHHHHHHHHH
RNLEFTCLQECINTADIIATGGGIIESEEAFNFLKNQKNIIWLDCNIDIIYSRINDDPHR
HCCCHHHHHHHHCHHHEEECCCCCEECHHHHHHHHCCCCEEEEECCCEEEEEECCCCCCC
PNANNKTIKQLNDLYCSRNLRYNEIAFKKFDSHLLSISEIYYELLNLIKASDQY
CCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNHDKSPIILIGFMGTGKSTIGKYVADEQNLSFIDIDSYIEEKYKLTIPEIFCKHGEQYF
CCCCCCCEEEEEECCCCHHHHHHHHCCCCCCEEEEHHHHHHHHHEECHHHHHHHHHHHHH
RNLEFTCLQECINTADIIATGGGIIESEEAFNFLKNQKNIIWLDCNIDIIYSRINDDPHR
HCCCHHHHHHHHCHHHEEECCCCCEECHHHHHHHHCCCCEEEEECCCEEEEEECCCCCCC
PNANNKTIKQLNDLYCSRNLRYNEIAFKKFDSHLLSISEIYYELLNLIKASDQY
CCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA