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The map label for this gene is argG

Identifier: 57651652

GI number: 57651652

Start: 966915

End: 968120

Strand: Reverse

Name: argG

Synonym: SACOL0964

Alternate gene names: 57651652

Gene position: 968120-966915 (Counterclockwise)

Preceding gene: 57651653

Following gene: 57651651

Centisome position: 34.46

GC content: 35.32

Gene sequence:

>1206_bases
ATGAAAGAGAAAATTGTTTTAGCATATTCAGGAGGACTAGATACAAGTGTGGCCGTTCAATGGCTTATCGACAAAGGATA
CGACGTTGTAGCTTGTTGCCTAGATGTTGGTGAAGGTAAAGATTTAGACATCGTTTATAAAAAAGCTTTAGATATGGGAG
CAGTTGAATGTCATATTATTGATGCAACAAAAGAATTTAGTGATGAGTATGTAAGTTATGCAATCAAAGGAAATTTAATG
TATGAAAATGCATATCCATTAGTTTCAGCTTTATCAAGACCATTAATCGCTAAAAAATTAGTAGAGATTGCTGAGAAAAC
AAATTCAGTAGGTATTGCACATGGTTGTACTGGTAAAGGGAATGACCAAGTACGTTTCGAAGTTGCCATTAAAGCATTAA
ACCCATCATTGAAAGCATTCGCACCTGTACGTGAGTGGGCATGGAGTCGTGAAGAAGAAATCGATTATGCAATTAAACAT
AATATCCCTGTATCAATCAACCATGATTCACCTTATTCTATCGATCAAAATCTATGGGGCAGAGCGAATGAATGTGGTAT
TTTAGAAGATCCTTATGCTGCGCCACCAGAGGATGCGTTCGATCTAACAAATGCTTTAGAAGAAACACCAGATACTGCTG
ATGAAATCATTTTAACGTTTGATAAAGGCATCCCAGTTCAAATTGATGGCAAAACATATGAATTAGACGATTTAATTTTA
ACGTTGAATGCATTAGCTGGTAAGCATGGTATCGGAAGAATTGACCATGTAGAAAATAGACTTGTAGGTATCAAATCAAG
AGAAATTTATGAGGCACCTGCTGCAGAAGTTATTTTAAAAGCGCATAAAGCATTAGAAACGATTACGTTAACGAAAGATG
TCGCACACTTTAAACCAATCATTGAGAAGCAATTTGCTGAACAACTATACAATGGACTTTGGTTCTCACCTTTAACTGAT
AGCTTGAAATTATTTATTGATAGTACTCAGCAATACGTAAGTGGTGATGTCAGAATTAAATTATTCAAAGGTAATGCCAT
CGTGAATGGTAGAAAATCACCTTACACATTATATGATGAAAAATTAGCAACTTATACAAAAGAAGATGCATTTAATCAAG
ACGCTGCTGTTGGCTTTATCGATATCTATGGTTTACCTACTCAAGTAAATGCGATGTTGCATGGAGGCTATAGCAATGAG
CAATAA

Upstream 100 bases:

>100_bases
TTTATGAATAAATATGTAAAATAATGGTTTTATTTTCATTAAAAGTTTGCTATCATGTGTTCATACGAAATATTCAGATA
ACTACAATGAGGTGAATTTT

Downstream 100 bases:

>100_bases
AGCTTGGGGCGGTAGATTTGAAGTACAACCTGAAGAGTGGGTTGACGACTTTAACGCATCCATTACTTTTGATCAAACGC
TCATAGATCAAGATATCGAA

Product: argininosuccinate synthase

Products: NA

Alternate protein names: Citrulline--aspartate ligase

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MKEKIVLAYSGGLDTSVAVQWLIDKGYDVVACCLDVGEGKDLDIVYKKALDMGAVECHIIDATKEFSDEYVSYAIKGNLM
YENAYPLVSALSRPLIAKKLVEIAEKTNSVGIAHGCTGKGNDQVRFEVAIKALNPSLKAFAPVREWAWSREEEIDYAIKH
NIPVSINHDSPYSIDQNLWGRANECGILEDPYAAPPEDAFDLTNALEETPDTADEIILTFDKGIPVQIDGKTYELDDLIL
TLNALAGKHGIGRIDHVENRLVGIKSREIYEAPAAEVILKAHKALETITLTKDVAHFKPIIEKQFAEQLYNGLWFSPLTD
SLKLFIDSTQQYVSGDVRIKLFKGNAIVNGRKSPYTLYDEKLATYTKEDAFNQDAAVGFIDIYGLPTQVNAMLHGGYSNE
Q

Sequences:

>Translated_401_residues
MKEKIVLAYSGGLDTSVAVQWLIDKGYDVVACCLDVGEGKDLDIVYKKALDMGAVECHIIDATKEFSDEYVSYAIKGNLM
YENAYPLVSALSRPLIAKKLVEIAEKTNSVGIAHGCTGKGNDQVRFEVAIKALNPSLKAFAPVREWAWSREEEIDYAIKH
NIPVSINHDSPYSIDQNLWGRANECGILEDPYAAPPEDAFDLTNALEETPDTADEIILTFDKGIPVQIDGKTYELDDLIL
TLNALAGKHGIGRIDHVENRLVGIKSREIYEAPAAEVILKAHKALETITLTKDVAHFKPIIEKQFAEQLYNGLWFSPLTD
SLKLFIDSTQQYVSGDVRIKLFKGNAIVNGRKSPYTLYDEKLATYTKEDAFNQDAAVGFIDIYGLPTQVNAMLHGGYSNE
Q
>Mature_401_residues
MKEKIVLAYSGGLDTSVAVQWLIDKGYDVVACCLDVGEGKDLDIVYKKALDMGAVECHIIDATKEFSDEYVSYAIKGNLM
YENAYPLVSALSRPLIAKKLVEIAEKTNSVGIAHGCTGKGNDQVRFEVAIKALNPSLKAFAPVREWAWSREEEIDYAIKH
NIPVSINHDSPYSIDQNLWGRANECGILEDPYAAPPEDAFDLTNALEETPDTADEIILTFDKGIPVQIDGKTYELDDLIL
TLNALAGKHGIGRIDHVENRLVGIKSREIYEAPAAEVILKAHKALETITLTKDVAHFKPIIEKQFAEQLYNGLWFSPLTD
SLKLFIDSTQQYVSGDVRIKLFKGNAIVNGRKSPYTLYDEKLATYTKEDAFNQDAAVGFIDIYGLPTQVNAMLHGGYSNE
Q

Specific function: Arginine biosynthesis; seventh step. [C]

COG id: COG0137

COG function: function code E; Argininosuccinate synthase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the argininosuccinate synthase family. Type 1 subfamily

Homologues:

Organism=Homo sapiens, GI53759107, Length=394, Percent_Identity=39.8477157360406, Blast_Score=292, Evalue=4e-79,
Organism=Homo sapiens, GI16950633, Length=394, Percent_Identity=39.8477157360406, Blast_Score=292, Evalue=4e-79,
Organism=Escherichia coli, GI1789563, Length=412, Percent_Identity=28.1553398058252, Blast_Score=144, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6324514, Length=400, Percent_Identity=37.25, Blast_Score=266, Evalue=3e-72,
Organism=Drosophila melanogaster, GI21358151, Length=410, Percent_Identity=37.5609756097561, Blast_Score=276, Evalue=1e-74,

Paralogues:

None

Copy number: 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): ASSY_STAA1 (A7X0H5)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001441546.1
- ProteinModelPortal:   A7X0H5
- SMR:   A7X0H5
- STRING:   A7X0H5
- EnsemblBacteria:   EBSTAT00000004386
- GeneID:   5559896
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_0956
- eggNOG:   COG0137
- GeneTree:   EBGT00050000023900
- HOGENOM:   HBG335267
- OMA:   VAVDVGQ
- ProtClustDB:   PRK00509
- BioCyc:   SAUR418127:SAHV_0956-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00005
- InterPro:   IPR001518
- InterPro:   IPR018223
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11587
- TIGRFAMs:   TIGR00032

Pfam domain/function: PF00764 Arginosuc_synth

EC number: =6.3.4.5

Molecular weight: Translated: 44456; Mature: 44456

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS00564 ARGININOSUCCIN_SYN_1; PS00565 ARGININOSUCCIN_SYN_2

Important sites: BINDING 85-85 BINDING 115-115 BINDING 117-117 BINDING 121-121 BINDING 121-121 BINDING 122-122 BINDING 125-125 BINDING 173-173 BINDING 258-258 BINDING 270-270

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEKIVLAYSGGLDTSVAVQWLIDKGYDVVACCLDVGEGKDLDIVYKKALDMGAVECHII
CCCEEEEEECCCCCHHHHHEEHHHCCCCEEEEEEECCCCCCCHHHHHHHCCCCCEEEEEE
DATKEFSDEYVSYAIKGNLMYENAYPLVSALSRPLIAKKLVEIAEKTNSVGIAHGCTGKG
ECHHHHHHHHEEEEEECCEEECCCCHHHHHHHCHHHHHHHHHHHHHCCCCEEEECCCCCC
NDQVRFEVAIKALNPSLKAFAPVREWAWSREEEIDYAIKHNIPVSINHDSPYSIDQNLWG
CCEEEEEEEEEECCCCHHHHHHHHHHCCCCCCCCCEEEECCCCEEECCCCCCCCCHHHCC
RANECGILEDPYAAPPEDAFDLTNALEETPDTADEIILTFDKGIPVQIDGKTYELDDLIL
CCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCEEECCCEEEHHHHHH
TLNALAGKHGIGRIDHVENRLVGIKSREIYEAPAAEVILKAHKALETITLTKDVAHFKPI
HHHHHHCCCCCCCHHHHHHHEEECCCCHHHCCCHHHHHHHHHHHHHHEEEHHHHHHHHHH
IEKQFAEQLYNGLWFSPLTDSLKLFIDSTQQYVSGDVRIKLFKGNAIVNGRKSPYTLYDE
HHHHHHHHHHCCEECCCCHHHHHHHHHCHHHHCCCCEEEEEEECCEEECCCCCCCEEHHH
KLATYTKEDAFNQDAAVGFIDIYGLPTQVNAMLHGGYSNEQ
HHHHHHHHHCCCCCCCEEEEEEECCCHHEEEEEECCCCCCC
>Mature Secondary Structure
MKEKIVLAYSGGLDTSVAVQWLIDKGYDVVACCLDVGEGKDLDIVYKKALDMGAVECHII
CCCEEEEEECCCCCHHHHHEEHHHCCCCEEEEEEECCCCCCCHHHHHHHCCCCCEEEEEE
DATKEFSDEYVSYAIKGNLMYENAYPLVSALSRPLIAKKLVEIAEKTNSVGIAHGCTGKG
ECHHHHHHHHEEEEEECCEEECCCCHHHHHHHCHHHHHHHHHHHHHCCCCEEEECCCCCC
NDQVRFEVAIKALNPSLKAFAPVREWAWSREEEIDYAIKHNIPVSINHDSPYSIDQNLWG
CCEEEEEEEEEECCCCHHHHHHHHHHCCCCCCCCCEEEECCCCEEECCCCCCCCCHHHCC
RANECGILEDPYAAPPEDAFDLTNALEETPDTADEIILTFDKGIPVQIDGKTYELDDLIL
CCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCEEECCCEEEHHHHHH
TLNALAGKHGIGRIDHVENRLVGIKSREIYEAPAAEVILKAHKALETITLTKDVAHFKPI
HHHHHHCCCCCCCHHHHHHHEEECCCCHHHCCCHHHHHHHHHHHHHHEEEHHHHHHHHHH
IEKQFAEQLYNGLWFSPLTDSLKLFIDSTQQYVSGDVRIKLFKGNAIVNGRKSPYTLYDE
HHHHHHHHHHCCEECCCCHHHHHHHHHCHHHHCCCCEEEEEEECCEEECCCCCCCEEHHH
KLATYTKEDAFNQDAAVGFIDIYGLPTQVNAMLHGGYSNEQ
HHHHHHHHHCCCCCCCEEEEEEECCCHHEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA