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The map label for this gene is ltaS

Identifier: 57651555

GI number: 57651555

Start: 798690

End: 800630

Strand: Direct

Name: ltaS

Synonym: SACOL0778

Alternate gene names: 57651555

Gene position: 798690-800630 (Clockwise)

Preceding gene: 57651554

Following gene: 57651556

Centisome position: 28.43

GC content: 31.12

Gene sequence:

>1941_bases
ATGAGTTCACAAAAAAAGAAAATTAGTCTTTTTGCGTTCTTCTTATTAACCGTAATAACGATTACCTTGAAGACGTATTT
TTCTTATTATGTTGATTTTTCTTTAGGTGTTAAAGGTTTAGTACAAAACTTAATATTATTGATGAATCCTTATAGTTTAG
TAGCACTGGTTTTAAGTGTGTTCCTATTCTTTAAAGGCAAAAAAGCATTTTGGTTCATGTTCATAGGCGGCTTCTTATTG
ACGTTCCTATTATATGCCAATGTTGTGTACTTTAGATTCTTCTCTGATTTTTTAACGTTTAGTACTTTAAACCAAGTAGG
TAACGTAGAATCTATGGGTGGTGCGGTTAGTGCATCATTCAAATGGTATGACTTTGTTTATTTCATTGATACGTTAGTTT
ACTTATTCATTTTAATATTTAAAACAAAATGGTTAGACACAAAAGCATTTAGTAAGAAATTTGTTCCTGTCGTAATGGCG
GCTTCAGTAGCATTATTCTTCTTAAACTTAGCTTTTGCTGAAACTGACAGACCAGAATTATTAACACGTACATTTGACCA
TAAATATTTAGTGAAATATTTAGGACCTTATAACTTTACAGTATACGATGGTGTTAAAACTATCGAAAATAATCAACAAA
AAGCGCTAGCATCTGAAGATGACTTAACAAAAGTATTAAATTATACGAAACAACGTCAAACAGAGCCTAACCCAGAATAT
TATGGGGTGGCAAAGAAGAAAAATATTATTAAGATTCATTTAGAAAGTTTCCAAACCTTCTTAATTAATAAAAAGGTTAA
TGGTAAAGAAGTAACACCGTTTTTAAACAAATTATCAAGTGGGAAAGAGCAATTCACATACTTCCCTAACTTTTTCCATC
AAACAGGTCAAGGTAAAACATCTGACTCTGAATTTACAATGGATAACAGTTTATACGGTTTACCGCAAGGTTCTGCCTTT
TCATTAAAAGGAGATAATACGTATCAGTCATTACCAGCAATTTTAGATCAAAAGCAAGGCTACAAATCTGATGTCATGCA
CGGTGACTATAAAACATTCTGGAACAGAGACCAAGTATATAAACACTTTGGTATCGATAAATTCTATGATGCAACATACT
ATGACATGTCAGATAAAAACGTTGTAAACTTAGGCTTGAAAGACAAAATTTTCTTTAAAGATTCTGCTAATTATCAAGCT
AAGATGAAATCACCATTCTATTCTCATTTAATTACATTGACTAACCACTATCCATTCACATTAGATGAAAAGGATGCAAC
TATTGAGAAATCAAACACAGGTGATGCAACAGTTGATGGTTATATTCAAACAGCACGTTATTTAGACGAAGCATTAGAAG
AATATATTAATGACTTGAAGAAAAAAGGATTATATGACAATTCAGTGATTATGATTTATGGTGACCACTATGGTATCTCT
GAAAACCATAACAATGCCATGGAAAAACTATTAGGTGAAAAAATCACACCGGCTAAATTTACAGATTTAAACAGAACTGG
TTTCTGGATTAAAATCCCTGGTAAATCTGGTGGTATCAATAATGAATATGCTGGTCAAGTCGATGTAATGCCAACAATTT
TACATTTGGCTGGTATAGATACGAAGAACTATTTAATGTTCGGTACTGATTTATTCTCTAAAGGTCATAATCAAGTAGTT
CCATTCAGAAATGGTGACTTTATAACAAAAGATTATAAATATGTTAATGGTAAGATTTATTCTAATAAAAATAATGAACT
CATAACTACTCAACCAGCTGATTTCGAAAAGAATAAAAAGCAAGTTGAAAAGGATCTCGAAATGAGTGACAACGTGCTTA
ATGGTGATTTGTTTAGATTCTACAAAAATCCAGACTTCAAAAAGGTAAATCCTTCGAAGTATAAATATGAAACAGGACCT
AAAGCAAACTCTAAAAAATAA

Upstream 100 bases:

>100_bases
AACTTTTAAACGCACTTATTAATTAACTACATAATGTTAATATCTAATTTATTCAAGTACTTTCGCAAGATTTATTATCT
AAATAACGGGGGAAAGAATC

Downstream 100 bases:

>100_bases
TATCTAAACACGAACTCGGATTGATAAAATATCAATCCGGGTTTTTATTATGTTCTTTTATATTATGTTTTACATTATAT
GTGTTGATAAAAAGGTATAT

Product: sulfatase family protein

Products: NA

Alternate protein names: LTA synthase; Polyglycerol phosphate synthase

Number of amino acids: Translated: 646; Mature: 645

Protein sequence:

>646_residues
MSSQKKKISLFAFFLLTVITITLKTYFSYYVDFSLGVKGLVQNLILLMNPYSLVALVLSVFLFFKGKKAFWFMFIGGFLL
TFLLYANVVYFRFFSDFLTFSTLNQVGNVESMGGAVSASFKWYDFVYFIDTLVYLFILIFKTKWLDTKAFSKKFVPVVMA
ASVALFFLNLAFAETDRPELLTRTFDHKYLVKYLGPYNFTVYDGVKTIENNQQKALASEDDLTKVLNYTKQRQTEPNPEY
YGVAKKKNIIKIHLESFQTFLINKKVNGKEVTPFLNKLSSGKEQFTYFPNFFHQTGQGKTSDSEFTMDNSLYGLPQGSAF
SLKGDNTYQSLPAILDQKQGYKSDVMHGDYKTFWNRDQVYKHFGIDKFYDATYYDMSDKNVVNLGLKDKIFFKDSANYQA
KMKSPFYSHLITLTNHYPFTLDEKDATIEKSNTGDATVDGYIQTARYLDEALEEYINDLKKKGLYDNSVIMIYGDHYGIS
ENHNNAMEKLLGEKITPAKFTDLNRTGFWIKIPGKSGGINNEYAGQVDVMPTILHLAGIDTKNYLMFGTDLFSKGHNQVV
PFRNGDFITKDYKYVNGKIYSNKNNELITTQPADFEKNKKQVEKDLEMSDNVLNGDLFRFYKNPDFKKVNPSKYKYETGP
KANSKK

Sequences:

>Translated_646_residues
MSSQKKKISLFAFFLLTVITITLKTYFSYYVDFSLGVKGLVQNLILLMNPYSLVALVLSVFLFFKGKKAFWFMFIGGFLL
TFLLYANVVYFRFFSDFLTFSTLNQVGNVESMGGAVSASFKWYDFVYFIDTLVYLFILIFKTKWLDTKAFSKKFVPVVMA
ASVALFFLNLAFAETDRPELLTRTFDHKYLVKYLGPYNFTVYDGVKTIENNQQKALASEDDLTKVLNYTKQRQTEPNPEY
YGVAKKKNIIKIHLESFQTFLINKKVNGKEVTPFLNKLSSGKEQFTYFPNFFHQTGQGKTSDSEFTMDNSLYGLPQGSAF
SLKGDNTYQSLPAILDQKQGYKSDVMHGDYKTFWNRDQVYKHFGIDKFYDATYYDMSDKNVVNLGLKDKIFFKDSANYQA
KMKSPFYSHLITLTNHYPFTLDEKDATIEKSNTGDATVDGYIQTARYLDEALEEYINDLKKKGLYDNSVIMIYGDHYGIS
ENHNNAMEKLLGEKITPAKFTDLNRTGFWIKIPGKSGGINNEYAGQVDVMPTILHLAGIDTKNYLMFGTDLFSKGHNQVV
PFRNGDFITKDYKYVNGKIYSNKNNELITTQPADFEKNKKQVEKDLEMSDNVLNGDLFRFYKNPDFKKVNPSKYKYETGP
KANSKK
>Mature_645_residues
SSQKKKISLFAFFLLTVITITLKTYFSYYVDFSLGVKGLVQNLILLMNPYSLVALVLSVFLFFKGKKAFWFMFIGGFLLT
FLLYANVVYFRFFSDFLTFSTLNQVGNVESMGGAVSASFKWYDFVYFIDTLVYLFILIFKTKWLDTKAFSKKFVPVVMAA
SVALFFLNLAFAETDRPELLTRTFDHKYLVKYLGPYNFTVYDGVKTIENNQQKALASEDDLTKVLNYTKQRQTEPNPEYY
GVAKKKNIIKIHLESFQTFLINKKVNGKEVTPFLNKLSSGKEQFTYFPNFFHQTGQGKTSDSEFTMDNSLYGLPQGSAFS
LKGDNTYQSLPAILDQKQGYKSDVMHGDYKTFWNRDQVYKHFGIDKFYDATYYDMSDKNVVNLGLKDKIFFKDSANYQAK
MKSPFYSHLITLTNHYPFTLDEKDATIEKSNTGDATVDGYIQTARYLDEALEEYINDLKKKGLYDNSVIMIYGDHYGISE
NHNNAMEKLLGEKITPAKFTDLNRTGFWIKIPGKSGGINNEYAGQVDVMPTILHLAGIDTKNYLMFGTDLFSKGHNQVVP
FRNGDFITKDYKYVNGKIYSNKNNELITTQPADFEKNKKQVEKDLEMSDNVLNGDLFRFYKNPDFKKVNPSKYKYETGPK
ANSKK

Specific function: Catalyzes the polymerization of lipoteichoic acid (LTA) polyglycerol phosphate, a reaction that presumably uses phosphatidylglycerol (PG) as substrate. Is required for staphylococcal growth and cell division process

COG id: COG1368

COG function: function code M; Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily

Gene ontology:

Cell location: Processed glycerol phosphate lipoteichoic acid synthase:Secreted

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LTA synthase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LTAS_STAA3 (Q2FIS2)

Other databases:

- EMBL:   CP000255
- RefSeq:   YP_493406.1
- ProteinModelPortal:   Q2FIS2
- STRING:   Q2FIS2
- EnsemblBacteria:   EBSTAT00000037644
- GeneID:   3913858
- GenomeReviews:   CP000255_GR
- KEGG:   saa:SAUSA300_0703
- eggNOG:   COG1368
- GeneTree:   EBGT00050000024670
- HOGENOM:   HBG425954
- OMA:   PQGSAYS
- ProtClustDB:   CLSK884851
- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR012160
- InterPro:   IPR000917
- Gene3D:   G3DSA:3.40.720.10
- PIRSF:   PIRSF005091

Pfam domain/function: PF00884 Sulfatase; SSF53649 Alkaline_phosphatase_core

EC number: NA

Molecular weight: Translated: 74401; Mature: 74270

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: NA

Important sites: ACT_SITE 300-300 BINDING 416-416

Signals:

None

Transmembrane regions:

HASH(0xb385bc4)-; HASH(0xc9cfb9c)-; HASH(0xcd75234)-; HASH(0xd683f78)-; HASH(0xd6c6e74)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSQKKKISLFAFFLLTVITITLKTYFSYYVDFSLGVKGLVQNLILLMNPYSLVALVLSV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHH
FLFFKGKKAFWFMFIGGFLLTFLLYANVVYFRFFSDFLTFSTLNQVGNVESMGGAVSASF
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCEECCC
KWYDFVYFIDTLVYLFILIFKTKWLDTKAFSKKFVPVVMAASVALFFLNLAFAETDRPEL
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
LTRTFDHKYLVKYLGPYNFTVYDGVKTIENNQQKALASEDDLTKVLNYTKQRQTEPNPEY
HHHHCCHHHHHHHCCCCCEEEECCHHHHCCCHHHHCCCHHHHHHHHHHHHHHCCCCCCCE
YGVAKKKNIIKIHLESFQTFLINKKVNGKEVTPFLNKLSSGKEQFTYFPNFFHQTGQGKT
EEECCCCCEEEEEHHHHHHHHEECCCCCCHHHHHHHHHCCCCHHEEECCHHHHHCCCCCC
SDSEFTMDNSLYGLPQGSAFSLKGDNTYQSLPAILDQKQGYKSDVMHGDYKTFWNRDQVY
CCCCEEECCCEECCCCCCEEEECCCCHHHHHHHHHHHCCCCHHHCCCCCHHHHCCHHHHH
KHFGIDKFYDATYYDMSDKNVVNLGLKDKIFFKDSANYQAKMKSPFYSHLITLTNHYPFT
HHCCCCHHCCCEEEECCCCCEEEECCCCEEEEECCCCCCEECCCCHHHHHHHHCCCCCEE
LDEKDATIEKSNTGDATVDGYIQTARYLDEALEEYINDLKKKGLYDNSVIMIYGDHYGIS
ECCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCC
ENHNNAMEKLLGEKITPAKFTDLNRTGFWIKIPGKSGGINNEYAGQVDVMPTILHLAGID
CCCHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCC
TKNYLMFGTDLFSKGHNQVVPFRNGDFITKDYKYVNGKIYSNKNNELITTQPADFEKNKK
CCCEEEEEHHHHHCCCCEEECCCCCCEEECCEEEECCEEEECCCCCEEEECCCCCHHHHH
QVEKDLEMSDNVLNGDLFRFYKNPDFKKVNPSKYKYETGPKANSKK
HHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCCCEEECCCCCCCCCH
>Mature Secondary Structure 
SSQKKKISLFAFFLLTVITITLKTYFSYYVDFSLGVKGLVQNLILLMNPYSLVALVLSV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHH
FLFFKGKKAFWFMFIGGFLLTFLLYANVVYFRFFSDFLTFSTLNQVGNVESMGGAVSASF
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCEECCC
KWYDFVYFIDTLVYLFILIFKTKWLDTKAFSKKFVPVVMAASVALFFLNLAFAETDRPEL
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
LTRTFDHKYLVKYLGPYNFTVYDGVKTIENNQQKALASEDDLTKVLNYTKQRQTEPNPEY
HHHHCCHHHHHHHCCCCCEEEECCHHHHCCCHHHHCCCHHHHHHHHHHHHHHCCCCCCCE
YGVAKKKNIIKIHLESFQTFLINKKVNGKEVTPFLNKLSSGKEQFTYFPNFFHQTGQGKT
EEECCCCCEEEEEHHHHHHHHEECCCCCCHHHHHHHHHCCCCHHEEECCHHHHHCCCCCC
SDSEFTMDNSLYGLPQGSAFSLKGDNTYQSLPAILDQKQGYKSDVMHGDYKTFWNRDQVY
CCCCEEECCCEECCCCCCEEEECCCCHHHHHHHHHHHCCCCHHHCCCCCHHHHCCHHHHH
KHFGIDKFYDATYYDMSDKNVVNLGLKDKIFFKDSANYQAKMKSPFYSHLITLTNHYPFT
HHCCCCHHCCCEEEECCCCCEEEECCCCEEEEECCCCCCEECCCCHHHHHHHHCCCCCEE
LDEKDATIEKSNTGDATVDGYIQTARYLDEALEEYINDLKKKGLYDNSVIMIYGDHYGIS
ECCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCC
ENHNNAMEKLLGEKITPAKFTDLNRTGFWIKIPGKSGGINNEYAGQVDVMPTILHLAGID
CCCHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCC
TKNYLMFGTDLFSKGHNQVVPFRNGDFITKDYKYVNGKIYSNKNNELITTQPADFEKNKK
CCCEEEEEHHHHHCCCCEEECCCCCCEEECCEEEECCEEEECCCCCEEEECCCCCHHHHH
QVEKDLEMSDNVLNGDLFRFYKNPDFKKVNPSKYKYETGPKANSKK
HHHHHHHHCCCCCCCHHHHHHCCCCCCCCCCCCEEECCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA