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The map label for this gene is dhaK [H]

Identifier: 57651491

GI number: 57651491

Start: 732688

End: 733653

Strand: Direct

Name: dhaK [H]

Synonym: SACOL0707

Alternate gene names: 57651491

Gene position: 732688-733653 (Clockwise)

Preceding gene: 57651490

Following gene: 57651492

Centisome position: 26.08

GC content: 35.71

Gene sequence:

>966_bases
ATGAAAAAGTTAATCAATAAAAAAGAAACATTTTTAACTGATATGCTTGAAGGATTGTTAATTGCGCACCCAGAGTTAGA
TCTGATTGCTAATACAGTTATTGTAAAAAAAGCTAAGAAAGAACATGGTGTAGCAATAGTCTCTGGAGGTGGAAGCGGAC
ATGAACCTGCGCATGCCGGTTTTGTTGCAGAAGGTATGCTAGATGCAGCGGTTTGTGGCGAAGTATTTACATCACCTACA
CCTGATAAAATATTAGAAGCTATTAAAGCAGTAGATACTGGTGATGGTGTATTACTAGTTGTAAAAAACTATGCAGGTGA
CGTGATGAATTTCGAAATGGCACAAGAGCTTGCAGAAATGGAAGGTATAAATGTTCAAACTGTTATTGTTCGTGACGACA
TTGCTGTGACAAACGAAGTACAACGTCGTGGTGTTGCAGGAACAGTGTTTGTTCATAAGCTTGCCGGTTATCTTGCTGAA
AAAGGTTATTCATTAACAGAGATAAAATCGCGTGTAGAAGCGTTGTTACCTGAAATTAAAAGTATTGGTATGGCAATTGA
GCCACCGCTTGTTCCAACTACTGGAAAATATGGCTTTGATATTGAAGACGACAAAATGGAAATCGGTATTGGTATACATG
GTGAAAAAGGTATTCATAGGGAAGAAGTAAAGGATATTGATCATATTGTTGGAACATTGTTAGACGAATTGTATAAAGAA
GTTACTGCCAATGATGTCATATTAATGGTAAATGGTATGGGTGGTACGCCGTTATCTGAATTAAATATCGTAACTAAATA
TATTCAACAAAATTTAGCTGCAAGAACGGTTAATGTTGCTAAATGGTTTGTTGGTGATTATATGACATCTTTAGACATGC
AAGGTTTTTCTATAACTATCGTGCCTAATAAACCAGAATATTTGGAAGCATTTTTAGCACCAACAACAAGTCAATACTTT
AAATAA

Upstream 100 bases:

>100_bases
AAAATATATTTGATAACGGTATCAGGTTAATTCTTTATGATAGCGCATTCATTTATTCTGTTTTATACTATGACTGATAA
TACCAAGGAGGTACAACATG

Downstream 100 bases:

>100_bases
GAAGTGAATATGAATAAATATACATTTATGAGGTGGCACAAATGAAAGTGAATGATATGAAAGCACGTTTATTAAATTTA
GAAGAAACGTTTAAAAAACA

Product: dihydroxyacetone kinase subunit DhaK

Products: ADP; glycerone phosphate

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MKKLINKKETFLTDMLEGLLIAHPELDLIANTVIVKKAKKEHGVAIVSGGGSGHEPAHAGFVAEGMLDAAVCGEVFTSPT
PDKILEAIKAVDTGDGVLLVVKNYAGDVMNFEMAQELAEMEGINVQTVIVRDDIAVTNEVQRRGVAGTVFVHKLAGYLAE
KGYSLTEIKSRVEALLPEIKSIGMAIEPPLVPTTGKYGFDIEDDKMEIGIGIHGEKGIHREEVKDIDHIVGTLLDELYKE
VTANDVILMVNGMGGTPLSELNIVTKYIQQNLAARTVNVAKWFVGDYMTSLDMQGFSITIVPNKPEYLEAFLAPTTSQYF
K

Sequences:

>Translated_321_residues
MKKLINKKETFLTDMLEGLLIAHPELDLIANTVIVKKAKKEHGVAIVSGGGSGHEPAHAGFVAEGMLDAAVCGEVFTSPT
PDKILEAIKAVDTGDGVLLVVKNYAGDVMNFEMAQELAEMEGINVQTVIVRDDIAVTNEVQRRGVAGTVFVHKLAGYLAE
KGYSLTEIKSRVEALLPEIKSIGMAIEPPLVPTTGKYGFDIEDDKMEIGIGIHGEKGIHREEVKDIDHIVGTLLDELYKE
VTANDVILMVNGMGGTPLSELNIVTKYIQQNLAARTVNVAKWFVGDYMTSLDMQGFSITIVPNKPEYLEAFLAPTTSQYF
K
>Mature_321_residues
MKKLINKKETFLTDMLEGLLIAHPELDLIANTVIVKKAKKEHGVAIVSGGGSGHEPAHAGFVAEGMLDAAVCGEVFTSPT
PDKILEAIKAVDTGDGVLLVVKNYAGDVMNFEMAQELAEMEGINVQTVIVRDDIAVTNEVQRRGVAGTVFVHKLAGYLAE
KGYSLTEIKSRVEALLPEIKSIGMAIEPPLVPTTGKYGFDIEDDKMEIGIGIHGEKGIHREEVKDIDHIVGTLLDELYKE
VTANDVILMVNGMGGTPLSELNIVTKYIQQNLAARTVNVAKWFVGDYMTSLDMQGFSITIVPNKPEYLEAFLAPTTSQYF
K

Specific function: Dihydroxyacetone binding subunit of the dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone [H]

COG id: COG2376

COG function: function code G; Dihydroxyacetone kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DhaK domain [H]

Homologues:

Organism=Homo sapiens, GI20149621, Length=334, Percent_Identity=38.622754491018, Blast_Score=225, Evalue=4e-59,
Organism=Escherichia coli, GI87081857, Length=346, Percent_Identity=41.3294797687861, Blast_Score=245, Evalue=3e-66,
Organism=Caenorhabditis elegans, GI17565018, Length=325, Percent_Identity=32.9230769230769, Blast_Score=182, Evalue=1e-46,
Organism=Saccharomyces cerevisiae, GI6321055, Length=333, Percent_Identity=35.4354354354354, Blast_Score=171, Evalue=2e-43,
Organism=Saccharomyces cerevisiae, GI6323570, Length=320, Percent_Identity=35, Blast_Score=169, Evalue=4e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004006
- InterPro:   IPR012736 [H]

Pfam domain/function: PF02733 Dak1 [H]

EC number: 2.7.1.29

Molecular weight: Translated: 34888; Mature: 34888

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLINKKETFLTDMLEGLLIAHPELDLIANTVIVKKAKKEHGVAIVSGGGSGHEPAHAG
CCCHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCC
FVAEGMLDAAVCGEVFTSPTPDKILEAIKAVDTGDGVLLVVKNYAGDVMNFEMAQELAEM
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHH
EGINVQTVIVRDDIAVTNEVQRRGVAGTVFVHKLAGYLAEKGYSLTEIKSRVEALLPEIK
CCCCEEEEEEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
SIGMAIEPPLVPTTGKYGFDIEDDKMEIGIGIHGEKGIHREEVKDIDHIVGTLLDELYKE
HCCCEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
VTANDVILMVNGMGGTPLSELNIVTKYIQQNLAARTVNVAKWFVGDYMTSLDMQGFSITI
HCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
VPNKPEYLEAFLAPTTSQYFK
ECCCHHHHHHHHCCCHHHHCC
>Mature Secondary Structure
MKKLINKKETFLTDMLEGLLIAHPELDLIANTVIVKKAKKEHGVAIVSGGGSGHEPAHAG
CCCHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCC
FVAEGMLDAAVCGEVFTSPTPDKILEAIKAVDTGDGVLLVVKNYAGDVMNFEMAQELAEM
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHH
EGINVQTVIVRDDIAVTNEVQRRGVAGTVFVHKLAGYLAEKGYSLTEIKSRVEALLPEIK
CCCCEEEEEEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
SIGMAIEPPLVPTTGKYGFDIEDDKMEIGIGIHGEKGIHREEVKDIDHIVGTLLDELYKE
HCCCEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
VTANDVILMVNGMGGTPLSELNIVTKYIQQNLAARTVNVAKWFVGDYMTSLDMQGFSITI
HCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
VPNKPEYLEAFLAPTTSQYFK
ECCCHHHHHHHHCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; glycerone

Specific reaction: ATP + glycerone = ADP + glycerone phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]