Click here to switch to the map view.

The map label for this gene is fhuG [H]

Identifier: 57651490

GI number: 57651490

Start: 731435

End: 732451

Strand: Direct

Name: fhuG [H]

Synonym: SACOL0706

Alternate gene names: 57651490

Gene position: 731435-732451 (Clockwise)

Preceding gene: 57651489

Following gene: 57651491

Centisome position: 26.04

GC content: 35.59

Gene sequence:

>1017_bases
ATGATTAGTTCAAATAATAAACGCAGACAATTGATAGCACTGGCTGTTTTTAGCATTCTACTATTTCTAGGTTGTACTTG
GAGTATTACCTCAGGTGAATACAACATACCTGTTGAAAGATTTTTCAAAACTTTAATTGGACAAGGTGATGCCATTGATG
AGTTAATCTTATTAGATTTCAGGTTACCTCGGATGATGATTACTATTTTGGCTGGCGCAGCGCTTAGTATTAGTGGTGCA
ATAGTGCAAAGTGTCACAAAAAATCCAATAGCTGAACCAGGTATATTAGGTATTAACGCAGGTGGCGGATTTGCAATCGC
ATTATTTATTGCAATTGGTAAAATTAATGCTGACAACTTTGTTTATGTACTGCCGTTAATAAGTATACTAGGTGGTATCA
CCACTGCATTGATTATTTTTATTTTCAGTTTTAATAAAAATGAAGGTGTTACACCTGCGAGTATGGTATTAATAGGTGTA
GGTTTACAAACAGCATTATATGGTGGCTCAATTACAATTATGTCAAAATTTGATGATAAGCAATCTGATTTCATCGCTGC
TTGGTTTGCAGGTAATATTTGGGGTGACGAATGGCCATTTGTCATTGCATTTTTACCGTGGGTGTTGATTATTATTCCTT
ACTTACTATTTAAATCGAATACACTAAATATTATTCATACGGGTGATAATATTGCACGAGGTCTAGGTGTAAGGTTAAGC
AGAGAACGTTTAATATTATTCTTTATCGCAGTGATGTTATCATCTGCTGCTGTAGCAGTAGCAGGTTCAATTTCGTTTAT
CGGATTAATGGGTCCGCATATTGCCAAACGTATCGTTGGACCACGTCACCAGTTGTTTTTACCAATTGCCATTTTAGTAG
GGGCATGTTTACTTGTTATAGCTGATACAATTGGCAAAATTGTATTACAACCAGGTGGGGTTCCAGCAGGTATTGTCGTA
GCAATTATTGGTGCACCGTATTTCTTATATTTAATGTACAAAACGAAAAATGTATAG

Upstream 100 bases:

>100_bases
TGATAGCACGATATTTAGGAGAAGCGCCTGTTGGTGCAATCATTTCATTTATCGGTGTTCCTTACTTTTTATATTTAGTT
AAAAAAGGAGGACGCTCAAT

Downstream 100 bases:

>100_bases
TGTCAATGGACACAACTTATTGCTATGAAAGGCACTTTATTATAAGGCTTTTCATAGCATTTTTTATTTAATGAGCCACT
CAAGACTATTTATTTTTTCA

Product: iron compound ABC transporter permease

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: Ferric hydroxamate uptake protein G; Ferrichrome transport system permease protein fhuG; Iron(III)-hydroxamate import system permease protein fhuG [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MISSNNKRRQLIALAVFSILLFLGCTWSITSGEYNIPVERFFKTLIGQGDAIDELILLDFRLPRMMITILAGAALSISGA
IVQSVTKNPIAEPGILGINAGGGFAIALFIAIGKINADNFVYVLPLISILGGITTALIIFIFSFNKNEGVTPASMVLIGV
GLQTALYGGSITIMSKFDDKQSDFIAAWFAGNIWGDEWPFVIAFLPWVLIIIPYLLFKSNTLNIIHTGDNIARGLGVRLS
RERLILFFIAVMLSSAAVAVAGSISFIGLMGPHIAKRIVGPRHQLFLPIAILVGACLLVIADTIGKIVLQPGGVPAGIVV
AIIGAPYFLYLMYKTKNV

Sequences:

>Translated_338_residues
MISSNNKRRQLIALAVFSILLFLGCTWSITSGEYNIPVERFFKTLIGQGDAIDELILLDFRLPRMMITILAGAALSISGA
IVQSVTKNPIAEPGILGINAGGGFAIALFIAIGKINADNFVYVLPLISILGGITTALIIFIFSFNKNEGVTPASMVLIGV
GLQTALYGGSITIMSKFDDKQSDFIAAWFAGNIWGDEWPFVIAFLPWVLIIIPYLLFKSNTLNIIHTGDNIARGLGVRLS
RERLILFFIAVMLSSAAVAVAGSISFIGLMGPHIAKRIVGPRHQLFLPIAILVGACLLVIADTIGKIVLQPGGVPAGIVV
AIIGAPYFLYLMYKTKNV
>Mature_338_residues
MISSNNKRRQLIALAVFSILLFLGCTWSITSGEYNIPVERFFKTLIGQGDAIDELILLDFRLPRMMITILAGAALSISGA
IVQSVTKNPIAEPGILGINAGGGFAIALFIAIGKINADNFVYVLPLISILGGITTALIIFIFSFNKNEGVTPASMVLIGV
GLQTALYGGSITIMSKFDDKQSDFIAAWFAGNIWGDEWPFVIAFLPWVLIIIPYLLFKSNTLNIIHTGDNIARGLGVRLS
RERLILFFIAVMLSSAAVAVAGSISFIGLMGPHIAKRIVGPRHQLFLPIAILVGACLLVIADTIGKIVLQPGGVPAGIVV
AIIGAPYFLYLMYKTKNV

Specific function: Part of the ABC transporter complex fhuBGCD involved in iron(3+)-hydroxamate import. Responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=333, Percent_Identity=32.4324324324324, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1790741, Length=297, Percent_Identity=33.3333333333333, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1786347, Length=285, Percent_Identity=33.3333333333333, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1786805, Length=307, Percent_Identity=33.2247557003257, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1786804, Length=331, Percent_Identity=29.0030211480363, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1788004, Length=286, Percent_Identity=32.1678321678322, Blast_Score=118, Evalue=6e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 36279; Mature: 36279

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00267 TACHYKININ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISSNNKRRQLIALAVFSILLFLGCTWSITSGEYNIPVERFFKTLIGQGDAIDELILLDF
CCCCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHCCCCCHHHHHHHHH
RLPRMMITILAGAALSISGAIVQSVTKNPIAEPGILGINAGGGFAIALFIAIGKINADNF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCE
VYVLPLISILGGITTALIIFIFSFNKNEGVTPASMVLIGVGLQTALYGGSITIMSKFDDK
EEHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHCCHHHHHCCCEEEEEECCCCC
QSDFIAAWFAGNIWGDEWPFVIAFLPWVLIIIPYLLFKSNTLNIIHTGDNIARGLGVRLS
CCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHCCCCEEC
RERLILFFIAVMLSSAAVAVAGSISFIGLMGPHIAKRIVGPRHQLFLPIAILVGACLLVI
HHHHHHHHHHHHHCCCHHHHHCCHHHHHHHCHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
ADTIGKIVLQPGGVPAGIVVAIIGAPYFLYLMYKTKNV
HHHHHHEEECCCCCCHHHHHHHHHCCHHEEEEEECCCC
>Mature Secondary Structure
MISSNNKRRQLIALAVFSILLFLGCTWSITSGEYNIPVERFFKTLIGQGDAIDELILLDF
CCCCCCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHCCCCCHHHHHHHHH
RLPRMMITILAGAALSISGAIVQSVTKNPIAEPGILGINAGGGFAIALFIAIGKINADNF
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCE
VYVLPLISILGGITTALIIFIFSFNKNEGVTPASMVLIGVGLQTALYGGSITIMSKFDDK
EEHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHCCHHHHHCCCEEEEEECCCCC
QSDFIAAWFAGNIWGDEWPFVIAFLPWVLIIIPYLLFKSNTLNIIHTGDNIARGLGVRLS
CCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHCCCCEEC
RERLILFFIAVMLSSAAVAVAGSISFIGLMGPHIAKRIVGPRHQLFLPIAILVGACLLVI
HHHHHHHHHHHHHCCCHHHHHCCHHHHHHHCHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
ADTIGKIVLQPGGVPAGIVVAIIGAPYFLYLMYKTKNV
HHHHHHEEECCCCCCHHHHHHHHHCCHHEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]