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The map label for this gene is fhuB [H]

Identifier: 57651489

GI number: 57651489

Start: 730434

End: 731438

Strand: Direct

Name: fhuB [H]

Synonym: SACOL0705

Alternate gene names: 57651489

Gene position: 730434-731438 (Clockwise)

Preceding gene: 57651488

Following gene: 57651490

Centisome position: 26.0

GC content: 35.92

Gene sequence:

>1005_bases
ATGACAAATAGAGAGAACCCAACGCCATTGAAGTTTTTATCCTATATTATAGGTTTAAGTATGATACTACTAATCACACT
ATTTATTTCTACATTAATAGGTGACGCCAAAATTCAAGCCTCTACAATTATAGAGGCTATTTTTAATTATAATCCTAGCA
ATCAACAGCAAAACATCATCAATGAGATTAGGATTCCCAGAAATATAGCAGCAGTAATTGTAGGTATGGCGCTTGCAGTT
TCTGGTGCGATTATACAAGGTGTTACTCGTAATGGTCTTGCTGATCCGGCGCTCATAGGTTTAAATTCAGGTGCTTCATT
TGCTTTAGCATTAACATATGCAGTTTTACCAAACACTTCATTTTTAATATTGATGTTTGCTGGATTTTTAGGTGCTATTC
TAGGAGGTGCTATTGTATTAATGATAGGCCGATCTAGACGTGATGGATTTAATCCGATGCGTATTATTTTAGCGGGTGCA
GCAGTAAGTGCTATGTTAACAGCGCTAAGTCAAGGTATTGCATTAGCTTTTAGACTAAATCAAACAGTAACATTTTGGAC
TGCTGGAGGCGTTTCAGGCACAACATGGTCACACCTTAAGTGGGCAATTCCATTAATTGGTATTGCGTTATTCATTATAT
TAACAATTAGTAAACAACTTACCATTTTAAATCTTGGTGAATCATTAGCTAAAGGTTTAGGTCAAAATGTAACAATGATC
AGAGGCATATGTTTAATTATTGCTATGATTCTAGCAGGTATTGCAGTTGCTATCGCTGGACAAGTTGCATTTGTAGGTTT
GATGGTACCTCATATAGCAAGATTTTTAATTGGAACTGATTATGCTAAAATTCTACCATTAACAGCCTTGTTAGGTGGGA
TACTCGTGCTTGTTGCCGATGTGATAGCACGATATTTAGGAGAAGCGCCTGTTGGTGCAATCATTTCATTTATCGGTGTT
CCTTACTTTTTATATTTAGTTAAAAAAGGAGGACGCTCAATATGA

Upstream 100 bases:

>100_bases
AAGATCCTAAAACTGGAAAACCTTTACTGGTAACTTATGACTTATGTCGCAGAGCTTATTCTTAATTAAGTAAGTTAATA
TGATAAAAAGGACAATTAAC

Downstream 100 bases:

>100_bases
TTAGTTCAAATAATAAACGCAGACAATTGATAGCACTGGCTGTTTTTAGCATTCTACTATTTCTAGGTTGTACTTGGAGT
ATTACCTCAGGTGAATACAA

Product: iron compound ABC transporter permease

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: Ferric hydroxamate uptake protein B; Ferrichrome transport system permease protein fhuB; Iron(III)-hydroxamate import system permease protein fhuB [H]

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MTNRENPTPLKFLSYIIGLSMILLITLFISTLIGDAKIQASTIIEAIFNYNPSNQQQNIINEIRIPRNIAAVIVGMALAV
SGAIIQGVTRNGLADPALIGLNSGASFALALTYAVLPNTSFLILMFAGFLGAILGGAIVLMIGRSRRDGFNPMRIILAGA
AVSAMLTALSQGIALAFRLNQTVTFWTAGGVSGTTWSHLKWAIPLIGIALFIILTISKQLTILNLGESLAKGLGQNVTMI
RGICLIIAMILAGIAVAIAGQVAFVGLMVPHIARFLIGTDYAKILPLTALLGGILVLVADVIARYLGEAPVGAIISFIGV
PYFLYLVKKGGRSI

Sequences:

>Translated_334_residues
MTNRENPTPLKFLSYIIGLSMILLITLFISTLIGDAKIQASTIIEAIFNYNPSNQQQNIINEIRIPRNIAAVIVGMALAV
SGAIIQGVTRNGLADPALIGLNSGASFALALTYAVLPNTSFLILMFAGFLGAILGGAIVLMIGRSRRDGFNPMRIILAGA
AVSAMLTALSQGIALAFRLNQTVTFWTAGGVSGTTWSHLKWAIPLIGIALFIILTISKQLTILNLGESLAKGLGQNVTMI
RGICLIIAMILAGIAVAIAGQVAFVGLMVPHIARFLIGTDYAKILPLTALLGGILVLVADVIARYLGEAPVGAIISFIGV
PYFLYLVKKGGRSI
>Mature_333_residues
TNRENPTPLKFLSYIIGLSMILLITLFISTLIGDAKIQASTIIEAIFNYNPSNQQQNIINEIRIPRNIAAVIVGMALAVS
GAIIQGVTRNGLADPALIGLNSGASFALALTYAVLPNTSFLILMFAGFLGAILGGAIVLMIGRSRRDGFNPMRIILAGAA
VSAMLTALSQGIALAFRLNQTVTFWTAGGVSGTTWSHLKWAIPLIGIALFIILTISKQLTILNLGESLAKGLGQNVTMIR
GICLIIAMILAGIAVAIAGQVAFVGLMVPHIARFLIGTDYAKILPLTALLGGILVLVADVIARYLGEAPVGAIISFIGVP
YFLYLVKKGGRSI

Specific function: Part of the ABC transporter complex fhuBGCD involved in iron(3+)-hydroxamate import. Responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790741, Length=331, Percent_Identity=35.3474320241692, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI1786805, Length=309, Percent_Identity=38.1877022653722, Blast_Score=150, Evalue=9e-38,
Organism=Escherichia coli, GI1790740, Length=285, Percent_Identity=32.9824561403509, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI1786347, Length=281, Percent_Identity=36.2989323843416, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1788004, Length=282, Percent_Identity=32.9787234042553, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1786804, Length=248, Percent_Identity=30.6451612903226, Blast_Score=103, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 35184; Mature: 35053

Theoretical pI: Translated: 10.66; Mature: 10.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNRENPTPLKFLSYIIGLSMILLITLFISTLIGDAKIQASTIIEAIFNYNPSNQQQNII
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHH
NEIRIPRNIAAVIVGMALAVSGAIIQGVTRNGLADPALIGLNSGASFALALTYAVLPNTS
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHHCCCH
FLILMFAGFLGAILGGAIVLMIGRSRRDGFNPMRIILAGAAVSAMLTALSQGIALAFRLN
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEEC
QTVTFWTAGGVSGTTWSHLKWAIPLIGIALFIILTISKQLTILNLGESLAKGLGQNVTMI
CEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHCCCCHHHH
RGICLIIAMILAGIAVAIAGQVAFVGLMVPHIARFLIGTDYAKILPLTALLGGILVLVAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
VIARYLGEAPVGAIISFIGVPYFLYLVKKGGRSI
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TNRENPTPLKFLSYIIGLSMILLITLFISTLIGDAKIQASTIIEAIFNYNPSNQQQNII
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHH
NEIRIPRNIAAVIVGMALAVSGAIIQGVTRNGLADPALIGLNSGASFALALTYAVLPNTS
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHHCCCH
FLILMFAGFLGAILGGAIVLMIGRSRRDGFNPMRIILAGAAVSAMLTALSQGIALAFRLN
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEEEEC
QTVTFWTAGGVSGTTWSHLKWAIPLIGIALFIILTISKQLTILNLGESLAKGLGQNVTMI
CEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHCCCCHHHH
RGICLIIAMILAGIAVAIAGQVAFVGLMVPHIARFLIGTDYAKILPLTALLGGILVLVAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
VIARYLGEAPVGAIISFIGVPYFLYLVKKGGRSI
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377; 8388528 [H]