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The map label for this gene is yjfH [C]

Identifier: 57651408

GI number: 57651408

Start: 600327

End: 601073

Strand: Direct

Name: yjfH [C]

Synonym: SACOL0578

Alternate gene names: 57651408

Gene position: 600327-601073 (Clockwise)

Preceding gene: 57651407

Following gene: 57651409

Centisome position: 21.37

GC content: 35.21

Gene sequence:

>747_bases
GTGGAAGATACGGTTATTGTTGGTAGGCATGCTGTTAGAGAAGCGATTATTACTGGGCATCCGATAAATAAGATATTGAT
TCAAGAAGGTATTAAAAAGCAACAAATTAATGAAATTTTAAAAAATGCAAAAGATCAAAAAATCATTGTTCAAACTGTAC
CAAAATCTAAATTAGATTTTTTAGCAAATGCACCACATCAGGGTGTTGCAGCGCTTATTGCACCATATGAATATGCTGAC
TTCGATCAATTTTTAAAACAGCAAAAAGAAAAAGAAGGTTTATTGACAGTACTTATATTAGACGGCTTAGAAGACCCACA
TAACTTGGGATCAATTTTAAGAACAGCCGATGCAACGGGAGTTGATGGTGTTATTATTCCTAAACGTCGTTCAGTTACAC
TAACGCAAACAGTTGCAAAAGCCTCAACAGGTGCAATTGAACATGTACCAGTTATTCGAGTGACAAATTTAGCTAAAACT
ATCGATGAACTAAAAGATAATGGCTTTTGGGTAGCTGGCACTGAAGCTAATAATGCAACAGATTATAGAAATCTAGAAGC
GGACATGTCATTGGCTATTGTAATTGGTAGCGAAGGACAGGGTATGAGTCGCCTAGTAAGTGATAAATGCGATTTTTATA
TTAAGATTCCAATGGTTGGACATGTAAACAGTTTGAATGCTTCGGTTGCAGCAAGTTTAATGATGTACGAAGTATTTCGA
AAAAGACATGATGTTGGAGAAATATAA

Upstream 100 bases:

>100_bases
GAAGCAGTGATAGGTTTTCTTTATTTAGAAAAAAGAGAAGAACGATTAGAGGCATTATTAAATAAAATAATAACAATAGT
AAACGAAAGGTAGTGACGAT

Downstream 100 bases:

>100_bases
TGAAAGAACGTTACTTAATCATTGATGGATACAATATGATAGGACAATCACCAACGCTAAGCGCCATTGCAAAAGAGAAT
TTAGAAGAAGCTAGAATGCA

Product: RNA methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MEDTVIVGRHAVREAIITGHPINKILIQEGIKKQQINEILKNAKDQKIIVQTVPKSKLDFLANAPHQGVAALIAPYEYAD
FDQFLKQQKEKEGLLTVLILDGLEDPHNLGSILRTADATGVDGVIIPKRRSVTLTQTVAKASTGAIEHVPVIRVTNLAKT
IDELKDNGFWVAGTEANNATDYRNLEADMSLAIVIGSEGQGMSRLVSDKCDFYIKIPMVGHVNSLNASVAASLMMYEVFR
KRHDVGEI

Sequences:

>Translated_248_residues
MEDTVIVGRHAVREAIITGHPINKILIQEGIKKQQINEILKNAKDQKIIVQTVPKSKLDFLANAPHQGVAALIAPYEYAD
FDQFLKQQKEKEGLLTVLILDGLEDPHNLGSILRTADATGVDGVIIPKRRSVTLTQTVAKASTGAIEHVPVIRVTNLAKT
IDELKDNGFWVAGTEANNATDYRNLEADMSLAIVIGSEGQGMSRLVSDKCDFYIKIPMVGHVNSLNASVAASLMMYEVFR
KRHDVGEI
>Mature_248_residues
MEDTVIVGRHAVREAIITGHPINKILIQEGIKKQQINEILKNAKDQKIIVQTVPKSKLDFLANAPHQGVAALIAPYEYAD
FDQFLKQQKEKEGLLTVLILDGLEDPHNLGSILRTADATGVDGVIIPKRRSVTLTQTVAKASTGAIEHVPVIRVTNLAKT
IDELKDNGFWVAGTEANNATDYRNLEADMSLAIVIGSEGQGMSRLVSDKCDFYIKIPMVGHVNSLNASVAASLMMYEVFR
KRHDVGEI

Specific function: Unknown

COG id: COG0566

COG function: function code J; rRNA methylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase TrmH family

Homologues:

Organism=Homo sapiens, GI40068479, Length=239, Percent_Identity=29.2887029288703, Blast_Score=96, Evalue=4e-20,
Organism=Escherichia coli, GI1790623, Length=246, Percent_Identity=38.2113821138211, Blast_Score=164, Evalue=7e-42,
Organism=Escherichia coli, GI1790083, Length=175, Percent_Identity=33.1428571428571, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1788935, Length=178, Percent_Identity=27.5280898876405, Blast_Score=74, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17555908, Length=258, Percent_Identity=26.3565891472868, Blast_Score=81, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6324775, Length=162, Percent_Identity=31.4814814814815, Blast_Score=81, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TRMHL_STAAC (Q5HIE3)

Other databases:

- EMBL:   CP000046
- RefSeq:   YP_185464.1
- ProteinModelPortal:   Q5HIE3
- SMR:   Q5HIE3
- STRING:   Q5HIE3
- EnsemblBacteria:   EBSTAT00000010086
- GeneID:   3235989
- GenomeReviews:   CP000046_GR
- KEGG:   sac:SACOL0578
- TIGR:   SACOL0578
- eggNOG:   COG0566
- GeneTree:   EBGT00050000024953
- HOGENOM:   HBG714057
- OMA:   MTASAWK
- ProtClustDB:   CLSK884713
- BioCyc:   SAUR93062:SACOL0578-MONOMER
- InterPro:   IPR004441
- InterPro:   IPR001537
- InterPro:   IPR013123
- SMART:   SM00967
- TIGRFAMs:   TIGR00186

Pfam domain/function: PF00588 SpoU_methylase; PF08032 SpoU_sub_bind

EC number: 2.1.1.- [C]

Molecular weight: Translated: 27208; Mature: 27208

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: BINDING 196-196 BINDING 216-216 BINDING 225-225

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDTVIVGRHAVREAIITGHPINKILIQEGIKKQQINEILKNAKDQKIIVQTVPKSKLDF
CCCCEEECHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEECCCHHHHH
LANAPHQGVAALIAPYEYADFDQFLKQQKEKEGLLTVLILDGLEDPHNLGSILRTADATG
HHCCCCCCHHHEECCCCCCCHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHCCCCC
VDGVIIPKRRSVTLTQTVAKASTGAIEHVPVIRVTNLAKTIDELKDNGFWVAGTEANNAT
CCCEEECCCCCEEHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHCCCEEEEECCCCCCC
DYRNLEADMSLAIVIGSEGQGMSRLVSDKCDFYIKIPMVGHVNSLNASVAASLMMYEVFR
CCCCCCCCCEEEEEECCCCCCHHHHHHCCCCEEEEECEEECCCCCCHHHHHHHHHHHHHH
KRHDVGEI
HHCCCCCC
>Mature Secondary Structure
MEDTVIVGRHAVREAIITGHPINKILIQEGIKKQQINEILKNAKDQKIIVQTVPKSKLDF
CCCCEEECHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHCCCCCEEEEEECCCHHHHH
LANAPHQGVAALIAPYEYADFDQFLKQQKEKEGLLTVLILDGLEDPHNLGSILRTADATG
HHCCCCCCHHHEECCCCCCCHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHCCCCC
VDGVIIPKRRSVTLTQTVAKASTGAIEHVPVIRVTNLAKTIDELKDNGFWVAGTEANNAT
CCCEEECCCCCEEHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHCCCEEEEECCCCCCC
DYRNLEADMSLAIVIGSEGQGMSRLVSDKCDFYIKIPMVGHVNSLNASVAASLMMYEVFR
CCCCCCCCCEEEEEECCCCCCHHHHHHCCCCEEEEECEEECCCCCCHHHHHHHHHHHHHH
KRHDVGEI
HHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA