Click here to switch to the map view.

The map label for this gene is clpL [H]

Identifier: 57651059

GI number: 57651059

Start: 2621890

End: 2623995

Strand: Direct

Name: clpL [H]

Synonym: SACOL2563

Alternate gene names: 57651059

Gene position: 2621890-2623995 (Clockwise)

Preceding gene: 57651057

Following gene: 57652289

Centisome position: 93.32

GC content: 34.71

Gene sequence:

>2106_bases
ATGAATAACGGTTTTTTCAATAGCGACTTTGATTCAATTTTTCGAAGAATGATGAAAGATATGCAAGGTTCAAATCAAGT
CGGAAACAAAAAGTACTATATTAATGGTAAAGAAGTTTCACCTGAAGAACTAGCGCAACTCACACAACAAGGTGGCAATC
ACTCTGCTGAACAAAGTGCGCAAGCTTTTCAACAAGCAGCACAAAGACAACAAGGGCAACAAGGTGGCAACGGCAATTAT
TTAGAACAAATTGGTCGTAACCTTACGCAAGAAGCACGTGACGGTTTATTAGATCCAGTCATTGGTCGTGATAAAGAAAT
TCAAGAAACTGCTGAAGTTTTAAGTAGACGAACTAAAAACAATCCTATATTAGTTGGAGAAGCTGGTGTTGGTAAAACTG
CGATTGTTGAAGGTTTAGCACAGGCAATCGTTGAAGGAAATGTACCAGCAGCAATCAAAGACAAAGAAATTATTTCTGTA
GACATTTCATCATTAGAAGCTGGAACGCAATATCGTGGTGCTTTTGAAGAAAATATTCAAAAATTAATCGAAGGTGTTAA
ATCTTCACAAAATGCCGTACTATTCTTTGATGAAATCCATCAAATTATCGGTTCAGGTGCCACAGGAAGTGATTCAGGTA
GCAAAGGGTTATCTGATATTTTGAAACCTGCATTAAGTCGTGGTGAGATTTCTATTATTGGTGCAACAACACAAGATGAA
TATCGAAACAATATTCTTAAAGATGCTGCATTAACGCGCAGATTTAATGAAGTGCTTGTTAATGAACCAAGCGCTAAAGA
TACTGTTGAAATTTTAAAAGGTATTCGCGAAAAATTCGAAGAACACCATCAAGTAAAATTACCAGATGACGTATTAAAAG
CATGTGTTGACTTATCAATTCAATATATTCCACAACGATTATTACCAGATAAAGCAATCGATGTGTTAGATATTACAGCA
GCACATTTATCTGCGCAAAGTCCAGCTGTCGATAAAGTTGAAACTGAAAAACGAATTTCTGAATTAGAAAATGATAAACG
TAAAGCAGTAAGTGCTGAAGAATATAAAAAAGCTGACGACATTCAAAATGAAATCAAATCATTACAAGATAAATTAGAAA
ATAGTAATGGTGAACATACTGCTGTTGCTACAGTTCATGATATTTCAGATACTATTCAACGATTAACTGGTATTCCAGTT
TCTCAAATGGATGATAACGATATTGAACGTTTAAAAAATATTTCTAATCGTTTAAGAAGTAAAATCATAGGTCAAGATCA
AGCTGTAGAAATGGTTTCACGTGCAATTCGCCGTAATCGTGCTGGGTTTGATGACGGCAACCGTCCAATTGGCAGTTTCC
TATTTGTTGGCCCTACTGGTGTTGGTAAAACAGAGCTTGCTAAACAATTAGCAATTGATTTATTTGGTAATAAAGATGCA
CTGATTCGACTTGATATGAGTGAATATAGTGACACAACAGCTGTTTCAAAAATGATTGGTACAACTGCTGGTTATGTTGG
TTATGATGACAATTCAAATACGTTAACTGAAAAAGTACGCCGTAATCCATACTCAGTCATTCTATTTGATGAAATCGAAA
AAGCAAATCCACAAATTTTAACATTGTTATTACAAGTAATGGATGATGGTAATTTGACTGATGGTCAAGGTAATGTCATC
AACTTTAAAAATACAATTATTATTTGTACATCAAATGCTGGCTTTGGCAATGGCAATGACGCTGAAGAAAAAGATATTAT
GCACGAAATGAAAAAATTCTTCCGCCCTGAATTCCTTAACCGCTTCAACGGCATCGTTGAATTCTTACATTTAGATAAAG
ATGCATTGCAAGATATCGTCAACTTATTATTAGACGATGTACAAGTTACATTAGACAAAAAAGGTATTACGATGGACGTT
TCTCAAGATGCGAAAGATTGGTTAATTGAAGAAGGCTATGATGAAGAATTAGGTGCACGTCCATTAAGACGTATTGTTGA
ACAGCAAGTACGTGACAAAATTACAGATTACTATTTAGATCATACAGACGTTAAACATGTGGATATAGATGTTGAGGATA
ACGAATTAGTCGTAAAAGGTAAATAA

Upstream 100 bases:

>100_bases
ATTAGTGGAAAAGTACAATTGCAATTGTATATAGTTTGCATAACGCTTCAAAAGTAATTTCTTTTTTGTTTAGTTCAAAA
AAATTTAGAGGTGATGTTAT

Downstream 100 bases:

>100_bases
CGACACTTTAACATATCGCGCATCAAAAATGAGCATCAGGTCGCCCTTGCCTGTGCTCATTTTTTTAATTATTTCCCTGG
AAAATGATTCGCTGTGTGCT

Product: ATP-dependent Clp protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 701; Mature: 701

Protein sequence:

>701_residues
MNNGFFNSDFDSIFRRMMKDMQGSNQVGNKKYYINGKEVSPEELAQLTQQGGNHSAEQSAQAFQQAAQRQQGQQGGNGNY
LEQIGRNLTQEARDGLLDPVIGRDKEIQETAEVLSRRTKNNPILVGEAGVGKTAIVEGLAQAIVEGNVPAAIKDKEIISV
DISSLEAGTQYRGAFEENIQKLIEGVKSSQNAVLFFDEIHQIIGSGATGSDSGSKGLSDILKPALSRGEISIIGATTQDE
YRNNILKDAALTRRFNEVLVNEPSAKDTVEILKGIREKFEEHHQVKLPDDVLKACVDLSIQYIPQRLLPDKAIDVLDITA
AHLSAQSPAVDKVETEKRISELENDKRKAVSAEEYKKADDIQNEIKSLQDKLENSNGEHTAVATVHDISDTIQRLTGIPV
SQMDDNDIERLKNISNRLRSKIIGQDQAVEMVSRAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLAIDLFGNKDA
LIRLDMSEYSDTTAVSKMIGTTAGYVGYDDNSNTLTEKVRRNPYSVILFDEIEKANPQILTLLLQVMDDGNLTDGQGNVI
NFKNTIIICTSNAGFGNGNDAEEKDIMHEMKKFFRPEFLNRFNGIVEFLHLDKDALQDIVNLLLDDVQVTLDKKGITMDV
SQDAKDWLIEEGYDEELGARPLRRIVEQQVRDKITDYYLDHTDVKHVDIDVEDNELVVKGK

Sequences:

>Translated_701_residues
MNNGFFNSDFDSIFRRMMKDMQGSNQVGNKKYYINGKEVSPEELAQLTQQGGNHSAEQSAQAFQQAAQRQQGQQGGNGNY
LEQIGRNLTQEARDGLLDPVIGRDKEIQETAEVLSRRTKNNPILVGEAGVGKTAIVEGLAQAIVEGNVPAAIKDKEIISV
DISSLEAGTQYRGAFEENIQKLIEGVKSSQNAVLFFDEIHQIIGSGATGSDSGSKGLSDILKPALSRGEISIIGATTQDE
YRNNILKDAALTRRFNEVLVNEPSAKDTVEILKGIREKFEEHHQVKLPDDVLKACVDLSIQYIPQRLLPDKAIDVLDITA
AHLSAQSPAVDKVETEKRISELENDKRKAVSAEEYKKADDIQNEIKSLQDKLENSNGEHTAVATVHDISDTIQRLTGIPV
SQMDDNDIERLKNISNRLRSKIIGQDQAVEMVSRAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLAIDLFGNKDA
LIRLDMSEYSDTTAVSKMIGTTAGYVGYDDNSNTLTEKVRRNPYSVILFDEIEKANPQILTLLLQVMDDGNLTDGQGNVI
NFKNTIIICTSNAGFGNGNDAEEKDIMHEMKKFFRPEFLNRFNGIVEFLHLDKDALQDIVNLLLDDVQVTLDKKGITMDV
SQDAKDWLIEEGYDEELGARPLRRIVEQQVRDKITDYYLDHTDVKHVDIDVEDNELVVKGK
>Mature_701_residues
MNNGFFNSDFDSIFRRMMKDMQGSNQVGNKKYYINGKEVSPEELAQLTQQGGNHSAEQSAQAFQQAAQRQQGQQGGNGNY
LEQIGRNLTQEARDGLLDPVIGRDKEIQETAEVLSRRTKNNPILVGEAGVGKTAIVEGLAQAIVEGNVPAAIKDKEIISV
DISSLEAGTQYRGAFEENIQKLIEGVKSSQNAVLFFDEIHQIIGSGATGSDSGSKGLSDILKPALSRGEISIIGATTQDE
YRNNILKDAALTRRFNEVLVNEPSAKDTVEILKGIREKFEEHHQVKLPDDVLKACVDLSIQYIPQRLLPDKAIDVLDITA
AHLSAQSPAVDKVETEKRISELENDKRKAVSAEEYKKADDIQNEIKSLQDKLENSNGEHTAVATVHDISDTIQRLTGIPV
SQMDDNDIERLKNISNRLRSKIIGQDQAVEMVSRAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLAIDLFGNKDA
LIRLDMSEYSDTTAVSKMIGTTAGYVGYDDNSNTLTEKVRRNPYSVILFDEIEKANPQILTLLLQVMDDGNLTDGQGNVI
NFKNTIIICTSNAGFGNGNDAEEKDIMHEMKKFFRPEFLNRFNGIVEFLHLDKDALQDIVNLLLDDVQVTLDKKGITMDV
SQDAKDWLIEEGYDEELGARPLRRIVEQQVRDKITDYYLDHTDVKHVDIDVEDNELVVKGK

Specific function: Required for the development of induced thermotolerance [H]

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=305, Percent_Identity=35.4098360655738, Blast_Score=163, Evalue=5e-40,
Organism=Escherichia coli, GI1788943, Length=688, Percent_Identity=40.5523255813954, Blast_Score=493, Evalue=1e-140,
Organism=Escherichia coli, GI1787109, Length=685, Percent_Identity=38.8321167883212, Blast_Score=481, Evalue=1e-137,
Organism=Saccharomyces cerevisiae, GI6320464, Length=722, Percent_Identity=38.9196675900277, Blast_Score=464, Evalue=1e-131,
Organism=Saccharomyces cerevisiae, GI6323002, Length=685, Percent_Identity=37.956204379562, Blast_Score=457, Evalue=1e-129,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR001943 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF10431 ClpB_D2-small; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 77837; Mature: 77837

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNGFFNSDFDSIFRRMMKDMQGSNQVGNKKYYINGKEVSPEELAQLTQQGGNHSAEQSA
CCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCHHHHH
QAFQQAAQRQQGQQGGNGNYLEQIGRNLTQEARDGLLDPVIGRDKEIQETAEVLSRRTKN
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCC
NPILVGEAGVGKTAIVEGLAQAIVEGNVPAAIKDKEIISVDISSLEAGTQYRGAFEENIQ
CCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEHHHHHCCCHHCCHHHHHHH
KLIEGVKSSQNAVLFFDEIHQIIGSGATGSDSGSKGLSDILKPALSRGEISIIGATTQDE
HHHHHHCCCCCEEEEHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCHHH
YRNNILKDAALTRRFNEVLVNEPSAKDTVEILKGIREKFEEHHQVKLPDDVLKACVDLSI
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
QYIPQRLLPDKAIDVLDITAAHLSAQSPAVDKVETEKRISELENDKRKAVSAEEYKKADD
HHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
IQNEIKSLQDKLENSNGEHTAVATVHDISDTIQRLTGIPVSQMDDNDIERLKNISNRLRS
HHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
KIIGQDQAVEMVSRAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLAIDLFGNKDA
HHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCC
LIRLDMSEYSDTTAVSKMIGTTAGYVGYDDNSNTLTEKVRRNPYSVILFDEIEKANPQIL
EEEEEHHHCCHHHHHHHHHHCCCCCCEECCCCHHHHHHHHCCCCEEEEEECCCCCCHHHH
TLLLQVMDDGNLTDGQGNVINFKNTIIICTSNAGFGNGNDAEEKDIMHEMKKFFRPEFLN
HHHHHHHCCCCCCCCCCCEEEECCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCHHHHH
RFNGIVEFLHLDKDALQDIVNLLLDDVQVTLDKKGITMDVSQDAKDWLIEEGYDEELGAR
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHEECCCCCEEECCCCHHHHHHCCCCCHHCCHH
PLRRIVEQQVRDKITDYYLDHTDVKHVDIDVEDNELVVKGK
HHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCEEEEECC
>Mature Secondary Structure
MNNGFFNSDFDSIFRRMMKDMQGSNQVGNKKYYINGKEVSPEELAQLTQQGGNHSAEQSA
CCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCHHHHH
QAFQQAAQRQQGQQGGNGNYLEQIGRNLTQEARDGLLDPVIGRDKEIQETAEVLSRRTKN
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCC
NPILVGEAGVGKTAIVEGLAQAIVEGNVPAAIKDKEIISVDISSLEAGTQYRGAFEENIQ
CCEEEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEHHHHHCCCHHCCHHHHHHH
KLIEGVKSSQNAVLFFDEIHQIIGSGATGSDSGSKGLSDILKPALSRGEISIIGATTQDE
HHHHHHCCCCCEEEEHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCHHH
YRNNILKDAALTRRFNEVLVNEPSAKDTVEILKGIREKFEEHHQVKLPDDVLKACVDLSI
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
QYIPQRLLPDKAIDVLDITAAHLSAQSPAVDKVETEKRISELENDKRKAVSAEEYKKADD
HHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
IQNEIKSLQDKLENSNGEHTAVATVHDISDTIQRLTGIPVSQMDDNDIERLKNISNRLRS
HHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
KIIGQDQAVEMVSRAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLAIDLFGNKDA
HHCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCC
LIRLDMSEYSDTTAVSKMIGTTAGYVGYDDNSNTLTEKVRRNPYSVILFDEIEKANPQIL
EEEEEHHHCCHHHHHHHHHHCCCCCCEECCCCHHHHHHHHCCCCEEEEEECCCCCCHHHH
TLLLQVMDDGNLTDGQGNVINFKNTIIICTSNAGFGNGNDAEEKDIMHEMKKFFRPEFLN
HHHHHHHCCCCCCCCCCCEEEECCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCHHHHH
RFNGIVEFLHLDKDALQDIVNLLLDDVQVTLDKKGITMDVSQDAKDWLIEEGYDEELGAR
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHEECCCCCEEECCCCHHHHHHCCCCCHHCCHH
PLRRIVEQQVRDKITDYYLDHTDVKHVDIDVEDNELVVKGK
HHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA