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The map label for this gene is hexR [C]

Identifier: 57650857

GI number: 57650857

Start: 2369843

End: 2370715

Strand: Direct

Name: hexR [C]

Synonym: SACOL2308

Alternate gene names: 57650857

Gene position: 2369843-2370715 (Clockwise)

Preceding gene: 57652247

Following gene: 57650859

Centisome position: 84.35

GC content: 29.32

Gene sequence:

>873_bases
ATGTCAAACGTACTAACAGAAATAGATAGTCAATATCCATATATGACTAAAAATGAAAAAAAGATAGCTAAATTTATACT
AAATTCACCTCAAAAGGTGATTAAAATGAGGTCTCAAGACTTAGCAAGCTTATTAGATATTAGTACATCATCAGTCATTC
GATTCAGCAAGAAAATTACTGATGGCGGTTTTCACGACTTGAAAATAAATATATCTAAATATGTTCCTAAAGCATCATCA
ATTTACAATGTTGAATTAATGAATAACGAAAGCACAGAATCTTTAAGAACTAAACTCCATACACGTACTACACGCGCACT
TAATCATGCAAATAACGAATTAAATGATAAAACTATTGATCAAATATGTCATTGTTTAAAACGTTCTGAGACGATTTTTA
TATATGGTTTTGGCGCATCTTTTGTAGTTGCTACCGACTTATACCAAAAGTTATCAAGAATAGGTCTTAATATTCAACTT
GTTCAAGAAACACATATTTTTGCTACATTATTAGCAACTCACAATTCGAACGACAGTGTTATTCTTATTACTAACAATGG
TACGCAAAGTGAAATGCAATCAATGGTTAAAGTTATTGATGACTACCATATACCTATAATTACAATTACTAGTACAAGGG
ATAATCCCGTAGCACAGGCATCAAATATTGTTTTAACTTATGGGAAAACTGATGAAAATGAGATGCATATGGGAGCAACA
ACTTCATTATTTGCTCAAATGTTCACTATTGATATTTTATATTATCGTTATGTTGCATTAAATTATCACGCATCATTAGA
TTTCATAACACAATCTAAAATGGCTTTAGATAACTATCGTAAACATTTATCAAATATTAACTTTAAACATTAA

Upstream 100 bases:

>100_bases
TATTTTTCATTCTCTTACGTTACAAGTTGTAAATACCATCGCGTTAAACAACAATAGCCAACGCTAATAAAATATATTGC
GTTAAAGTGGAGTGATTAAT

Downstream 100 bases:

>100_bases
CAGTCTTATATAAATTCTTTAATCATGTCATATAATAATTTATGCATCATTTTCAAAGCTTACATGTCTTTTATCTTGTA
TAACATACGCATATGACCAA

Product: RpiR family phosphosugar-binding transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 290; Mature: 289

Protein sequence:

>290_residues
MSNVLTEIDSQYPYMTKNEKKIAKFILNSPQKVIKMRSQDLASLLDISTSSVIRFSKKITDGGFHDLKINISKYVPKASS
IYNVELMNNESTESLRTKLHTRTTRALNHANNELNDKTIDQICHCLKRSETIFIYGFGASFVVATDLYQKLSRIGLNIQL
VQETHIFATLLATHNSNDSVILITNNGTQSEMQSMVKVIDDYHIPIITITSTRDNPVAQASNIVLTYGKTDENEMHMGAT
TSLFAQMFTIDILYYRYVALNYHASLDFITQSKMALDNYRKHLSNINFKH

Sequences:

>Translated_290_residues
MSNVLTEIDSQYPYMTKNEKKIAKFILNSPQKVIKMRSQDLASLLDISTSSVIRFSKKITDGGFHDLKINISKYVPKASS
IYNVELMNNESTESLRTKLHTRTTRALNHANNELNDKTIDQICHCLKRSETIFIYGFGASFVVATDLYQKLSRIGLNIQL
VQETHIFATLLATHNSNDSVILITNNGTQSEMQSMVKVIDDYHIPIITITSTRDNPVAQASNIVLTYGKTDENEMHMGAT
TSLFAQMFTIDILYYRYVALNYHASLDFITQSKMALDNYRKHLSNINFKH
>Mature_289_residues
SNVLTEIDSQYPYMTKNEKKIAKFILNSPQKVIKMRSQDLASLLDISTSSVIRFSKKITDGGFHDLKINISKYVPKASSI
YNVELMNNESTESLRTKLHTRTTRALNHANNELNDKTIDQICHCLKRSETIFIYGFGASFVVATDLYQKLSRIGLNIQLV
QETHIFATLLATHNSNDSVILITNNGTQSEMQSMVKVIDDYHIPIITITSTRDNPVAQASNIVLTYGKTDENEMHMGATT
SLFAQMFTIDILYYRYVALNYHASLDFITQSKMALDNYRKHLSNINFKH

Specific function: Represses The Expression Of The Hex Regulon (Zwf, Eda, Glp And Gap) (By Similarity). [C]

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788159, Length=289, Percent_Identity=24.9134948096886, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1788767, Length=277, Percent_Identity=27.0758122743682, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI87082130, Length=257, Percent_Identity=24.5136186770428, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI87082369, Length=247, Percent_Identity=21.4574898785425, Blast_Score=81, Evalue=8e-17,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 33005; Mature: 32874

Theoretical pI: Translated: 8.88; Mature: 8.88

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNVLTEIDSQYPYMTKNEKKIAKFILNSPQKVIKMRSQDLASLLDISTSSVIRFSKKIT
CCCHHHHHHCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCC
DGGFHDLKINISKYVPKASSIYNVELMNNESTESLRTKLHTRTTRALNHANNELNDKTID
CCCCEEEEEEHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
QICHCLKRSETIFIYGFGASFVVATDLYQKLSRIGLNIQLVQETHIFATLLATHNSNDSV
HHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHCCCEEEEEEHHHHEEEEEEECCCCCCE
ILITNNGTQSEMQSMVKVIDDYHIPIITITSTRDNPVAQASNIVLTYGKTDENEMHMGAT
EEEECCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCEEEEECCCCCCCEECCHH
TSLFAQMFTIDILYYRYVALNYHASLDFITQSKMALDNYRKHLSNINFKH
HHHHHHHHHHHHHHHHHHHEEECCCEEHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SNVLTEIDSQYPYMTKNEKKIAKFILNSPQKVIKMRSQDLASLLDISTSSVIRFSKKIT
CCHHHHHHCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCC
DGGFHDLKINISKYVPKASSIYNVELMNNESTESLRTKLHTRTTRALNHANNELNDKTID
CCCCEEEEEEHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
QICHCLKRSETIFIYGFGASFVVATDLYQKLSRIGLNIQLVQETHIFATLLATHNSNDSV
HHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHCCCEEEEEEHHHHEEEEEEECCCCCCE
ILITNNGTQSEMQSMVKVIDDYHIPIITITSTRDNPVAQASNIVLTYGKTDENEMHMGAT
EEEECCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCEEEEECCCCCCCEECCHH
TSLFAQMFTIDILYYRYVALNYHASLDFITQSKMALDNYRKHLSNINFKH
HHHHHHHHHHHHHHHHHHHEEECCCEEHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]