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The map label for this gene is gcp [H]

Identifier: 57650721

GI number: 57650721

Start: 2097999

End: 2099024

Strand: Reverse

Name: gcp [H]

Synonym: SACOL2038

Alternate gene names: 57650721

Gene position: 2099024-2097999 (Counterclockwise)

Preceding gene: 57650722

Following gene: 57650718

Centisome position: 74.71

GC content: 37.91

Gene sequence:

>1026_bases
ATGACTAAAGATATATTAATACTAGCTGTTGAAACAAGTTGTGATGAAACAAGCGTTAGTGTTATAAAAAATGGCAGAGA
TATTTTATCAAATACAGTTTTAAGTCAGATTGAAAGTCATAAACGATTTGGCGGTGTCGTTCCCGAAGTGGCAAGTAGAC
ATCACGTTGAAGGTATAACAGCAACAATAAACGAGGCTCTAGGGGATGCCGATGTATCAATAGAAGATATTGATGCCATA
GCGGTTACAGAAGGCCCTGGACTAATTGGTGCGTTACTAATAGGTGTTAATGCAGCCAAAGCATTGGCATTTGCTTACGA
TAAGCCACTTATTCCTGTTCATCATATTGCAGGACATATATATGCTAATCACATAGAAGAGCCATTAACATTCCCGCTAA
TTGCACTTATTGTTTCAGGTGGACATACTGAATTAGTTTATATGAAGGATCATTTATCATTTGAAGTCATTGGTGAAACA
CGAGATGACGCAGTAGGTGAGGCTTATGATAAAGTGGCACGAACAATTGGTTTAAATTATCCAGGTGGTCCACAAGTTGA
TCGGTTGGCTGCTGAAGGTGAAGATACTTATTCATTCCCTCGTGTTTGGTTGGATAAAGATAGTTATGATTTTAGTTTTA
GTGGGTTGAAAAGTGCCGTAATCAATCAACTTCACAATCAACGACAAAAAAATATTCCAATCATTGAAGCTAACGTAGCA
ACGAGCTTTCAAAACAGTGTTGTAGAGGTGCTCACGTTTAAAGCTATTCAAGCTTGTAAAGAATATGGTGTTCAGCGATT
AATTGTTGCTGGTGGCGTGGCGAGTAATAAAGGATTACGTCAATCTTTAGCGGATCAATGCAAAGTCAATGACATTCAAT
TAACTATCCCAAGTCCTAAATTATGCACAGATAATGCTGCAATGATAGGCGTTGCCGGCCACTATTTGTATCAGCAAGGT
CGATTTGCTGATTTAGCATTAAATGGGCACAGCAATATAGATTTAGAAGAGTATTCTGCAGAATAA

Upstream 100 bases:

>100_bases
GCACAACATGTATATGAAAATTTAGGATTTCAATATGGTGGTAAACGTAAAAATTATTATGGTGAAGGTGAGGACGCAAT
GGTTATGTGGGTGAATTTAA

Downstream 100 bases:

>100_bases
AATAAACGTCAGTTATTAACATGATTACTATGAACATTATTGAAACTGTTCATAGTCTTCTGTCATGTGATAGCTGACGT
TTTTATGTTTAAAGTTAAAT

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MTKDILILAVETSCDETSVSVIKNGRDILSNTVLSQIESHKRFGGVVPEVASRHHVEGITATINEALGDADVSIEDIDAI
AVTEGPGLIGALLIGVNAAKALAFAYDKPLIPVHHIAGHIYANHIEEPLTFPLIALIVSGGHTELVYMKDHLSFEVIGET
RDDAVGEAYDKVARTIGLNYPGGPQVDRLAAEGEDTYSFPRVWLDKDSYDFSFSGLKSAVINQLHNQRQKNIPIIEANVA
TSFQNSVVEVLTFKAIQACKEYGVQRLIVAGGVASNKGLRQSLADQCKVNDIQLTIPSPKLCTDNAAMIGVAGHYLYQQG
RFADLALNGHSNIDLEEYSAE

Sequences:

>Translated_341_residues
MTKDILILAVETSCDETSVSVIKNGRDILSNTVLSQIESHKRFGGVVPEVASRHHVEGITATINEALGDADVSIEDIDAI
AVTEGPGLIGALLIGVNAAKALAFAYDKPLIPVHHIAGHIYANHIEEPLTFPLIALIVSGGHTELVYMKDHLSFEVIGET
RDDAVGEAYDKVARTIGLNYPGGPQVDRLAAEGEDTYSFPRVWLDKDSYDFSFSGLKSAVINQLHNQRQKNIPIIEANVA
TSFQNSVVEVLTFKAIQACKEYGVQRLIVAGGVASNKGLRQSLADQCKVNDIQLTIPSPKLCTDNAAMIGVAGHYLYQQG
RFADLALNGHSNIDLEEYSAE
>Mature_340_residues
TKDILILAVETSCDETSVSVIKNGRDILSNTVLSQIESHKRFGGVVPEVASRHHVEGITATINEALGDADVSIEDIDAIA
VTEGPGLIGALLIGVNAAKALAFAYDKPLIPVHHIAGHIYANHIEEPLTFPLIALIVSGGHTELVYMKDHLSFEVIGETR
DDAVGEAYDKVARTIGLNYPGGPQVDRLAAEGEDTYSFPRVWLDKDSYDFSFSGLKSAVINQLHNQRQKNIPIIEANVAT
SFQNSVVEVLTFKAIQACKEYGVQRLIVAGGVASNKGLRQSLADQCKVNDIQLTIPSPKLCTDNAAMIGVAGHYLYQQGR
FADLALNGHSNIDLEEYSAE

Specific function: Critical mediator involved in the modification of cell wall peptidoglycan synthesis and/or cell division. Essential for cell viability [H]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family [H]

Homologues:

Organism=Homo sapiens, GI116812636, Length=332, Percent_Identity=32.5301204819277, Blast_Score=161, Evalue=8e-40,
Organism=Homo sapiens, GI8923380, Length=326, Percent_Identity=30.3680981595092, Blast_Score=135, Evalue=4e-32,
Organism=Escherichia coli, GI1789445, Length=336, Percent_Identity=42.2619047619048, Blast_Score=290, Evalue=7e-80,
Organism=Caenorhabditis elegans, GI17557464, Length=325, Percent_Identity=30.1538461538462, Blast_Score=145, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI71995670, Length=333, Percent_Identity=29.4294294294294, Blast_Score=123, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6320099, Length=356, Percent_Identity=30.6179775280899, Blast_Score=135, Evalue=7e-33,
Organism=Saccharomyces cerevisiae, GI6322891, Length=294, Percent_Identity=27.5510204081633, Blast_Score=105, Evalue=1e-23,
Organism=Drosophila melanogaster, GI20129063, Length=334, Percent_Identity=30.5389221556886, Blast_Score=157, Evalue=9e-39,
Organism=Drosophila melanogaster, GI21357207, Length=330, Percent_Identity=28.1818181818182, Blast_Score=127, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017860
- InterPro:   IPR017861 [H]

Pfam domain/function: PF00814 Peptidase_M22 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 36819; Mature: 36688

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKDILILAVETSCDETSVSVIKNGRDILSNTVLSQIESHKRFGGVVPEVASRHHVEGIT
CCCCEEEEEEECCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHH
ATINEALGDADVSIEDIDAIAVTEGPGLIGALLIGVNAAKALAFAYDKPLIPVHHIAGHI
HHHHHHCCCCCCCHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
YANHIEEPLTFPLIALIVSGGHTELVYMKDHLSFEVIGETRDDAVGEAYDKVARTIGLNY
HHHHCCCCHHHHHHHHHHCCCCEEEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHCCCC
PGGPQVDRLAAEGEDTYSFPRVWLDKDSYDFSFSGLKSAVINQLHNQRQKNIPIIEANVA
CCCCCHHHHHCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECHH
TSFQNSVVEVLTFKAIQACKEYGVQRLIVAGGVASNKGLRQSLADQCKVNDIQLTIPSPK
HHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHCCCCEEEEEECCCC
LCTDNAAMIGVAGHYLYQQGRFADLALNGHSNIDLEEYSAE
CCCCCCEEEEHHHHHHHHCCCEEEEEECCCCCCCHHHCCCC
>Mature Secondary Structure 
TKDILILAVETSCDETSVSVIKNGRDILSNTVLSQIESHKRFGGVVPEVASRHHVEGIT
CCCEEEEEEECCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCHHH
ATINEALGDADVSIEDIDAIAVTEGPGLIGALLIGVNAAKALAFAYDKPLIPVHHIAGHI
HHHHHHCCCCCCCHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
YANHIEEPLTFPLIALIVSGGHTELVYMKDHLSFEVIGETRDDAVGEAYDKVARTIGLNY
HHHHCCCCHHHHHHHHHHCCCCEEEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHCCCC
PGGPQVDRLAAEGEDTYSFPRVWLDKDSYDFSFSGLKSAVINQLHNQRQKNIPIIEANVA
CCCCCHHHHHCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECHH
TSFQNSVVEVLTFKAIQACKEYGVQRLIVAGGVASNKGLRQSLADQCKVNDIQLTIPSPK
HHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHCCCCEEEEEECCCC
LCTDNAAMIGVAGHYLYQQGRFADLALNGHSNIDLEEYSAE
CCCCCCEEEEHHHHHHHHCCCEEEEEECCCCCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA