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The map label for this gene is pheA [H]

Identifier: 57650667

GI number: 57650667

Start: 2040724

End: 2041518

Strand: Direct

Name: pheA [H]

Synonym: SACOL1977

Alternate gene names: 57650667

Gene position: 2040724-2041518 (Clockwise)

Preceding gene: 57650666

Following gene: 57650671

Centisome position: 72.64

GC content: 32.83

Gene sequence:

>795_bases
ATGCAATTATATTATTTAGGCCCTAAAGGTACATTTTCATATTTGGCTTGTCGTCAGTATTTTTCTGAAAATGAAGCAAC
TTTTCAACCAAAGTCAAATTTTTTTGAAGTCATCAAGGCAGTTGCAGATGATGACACATCGATTGGTGTTGTCCCTATTG
AAAATTCTATAGAAGGAACAATCAACATTGTGGCAGATGCACTTGCACAGCAAGATGTCTTTGCACACGGTGAAATACGT
TTAGATATTAACTTTGCATTATATGGTAATGGAACAGATTCCATTTCTGATATTAAAAAAGTGTATTCTATTGCACCAGC
AATCAGTCAAACAACAAATTACATACATCAACATCAATTTGACTATGATTATGTCGACAGTACAATTCAAAGTTTGACTA
AAATTGAAAATGGCGTTGCAGCAATTGCACCTTTAGGTAGTGGCGAAGCTTATGGTTTTACACCTATTGATACACATATT
GAAGACTATCCACATAACGTGACACGTTTTTTAGTTATAAAAAATCAGCAGCAATTTGATCAAAATGCGACATCATTGAT
GTTTTTAATTACACCAATGCATGATAAACCTGGGTTGTTAGCAAGTGTGCTTAATACATTTGCTTTGTTTAATATTAATT
TATCCTGGATTGAGTCTCGTCCTTTAAAAACACAATTAGGTATGTATCGATTTTTCGTTCAGGCTGATTCTGCAATTACA
ACCGATATAAAGAAAGTCATTGCTATTTTAGAAACCTTAGATTTCAAAGTAGAAATGATTGGTGCTTTTAATTAA

Upstream 100 bases:

>100_bases
TATGACAATACAGTAAAAGATCCAAACTTTTTCTATAAAAAGAAAGAATCAAATGCTAACCAGTGCCCTTTCCATCATTA
AGTTAGTAGAGGTGTAGCAT

Downstream 100 bases:

>100_bases
ACTTTATTTTCTAGGTTCTACAATTTAAATAAAATAAAGAGTCAACCAAGGATTAAAATAGGAATCCATCCTTGGTTGAC
TTTCTTTTGTTTGTATTGTT

Product: prephenate dehydratase

Products: NA

Alternate protein names: PDT; MjPDT [H]

Number of amino acids: Translated: 264; Mature: 264

Protein sequence:

>264_residues
MQLYYLGPKGTFSYLACRQYFSENEATFQPKSNFFEVIKAVADDDTSIGVVPIENSIEGTINIVADALAQQDVFAHGEIR
LDINFALYGNGTDSISDIKKVYSIAPAISQTTNYIHQHQFDYDYVDSTIQSLTKIENGVAAIAPLGSGEAYGFTPIDTHI
EDYPHNVTRFLVIKNQQQFDQNATSLMFLITPMHDKPGLLASVLNTFALFNINLSWIESRPLKTQLGMYRFFVQADSAIT
TDIKKVIAILETLDFKVEMIGAFN

Sequences:

>Translated_264_residues
MQLYYLGPKGTFSYLACRQYFSENEATFQPKSNFFEVIKAVADDDTSIGVVPIENSIEGTINIVADALAQQDVFAHGEIR
LDINFALYGNGTDSISDIKKVYSIAPAISQTTNYIHQHQFDYDYVDSTIQSLTKIENGVAAIAPLGSGEAYGFTPIDTHI
EDYPHNVTRFLVIKNQQQFDQNATSLMFLITPMHDKPGLLASVLNTFALFNINLSWIESRPLKTQLGMYRFFVQADSAIT
TDIKKVIAILETLDFKVEMIGAFN
>Mature_264_residues
MQLYYLGPKGTFSYLACRQYFSENEATFQPKSNFFEVIKAVADDDTSIGVVPIENSIEGTINIVADALAQQDVFAHGEIR
LDINFALYGNGTDSISDIKKVYSIAPAISQTTNYIHQHQFDYDYVDSTIQSLTKIENGVAAIAPLGSGEAYGFTPIDTHI
EDYPHNVTRFLVIKNQQQFDQNATSLMFLITPMHDKPGLLASVLNTFALFNINLSWIESRPLKTQLGMYRFFVQADSAIT
TDIKKVIAILETLDFKVEMIGAFN

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=271, Percent_Identity=24.7232472324723, Blast_Score=92, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01842 ACT; PF00800 PDT [H]

EC number: =4.2.1.51 [H]

Molecular weight: Translated: 29508; Mature: 29508

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLYYLGPKGTFSYLACRQYFSENEATFQPKSNFFEVIKAVADDDTSIGVVPIENSIEGT
CEEEEECCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCHH
INIVADALAQQDVFAHGEIRLDINFALYGNGTDSISDIKKVYSIAPAISQTTNYIHQHQF
HHHHHHHHHHHCCEECCEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
DYDYVDSTIQSLTKIENGVAAIAPLGSGEAYGFTPIDTHIEDYPHNVTRFLVIKNQQQFD
CHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCHHCCCCCEEEEEEEECHHHHC
QNATSLMFLITPMHDKPGLLASVLNTFALFNINLSWIESRPLKTQLGMYRFFVQADSAIT
CCCCEEEEEEECCCCCCCHHHHHHHHHHEEEEEEEEECCCCCHHHHHHEEEEEECCCHHH
TDIKKVIAILETLDFKVEMIGAFN
HHHHHHHHHHHHHCCEEEEEECCC
>Mature Secondary Structure
MQLYYLGPKGTFSYLACRQYFSENEATFQPKSNFFEVIKAVADDDTSIGVVPIENSIEGT
CEEEEECCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCHH
INIVADALAQQDVFAHGEIRLDINFALYGNGTDSISDIKKVYSIAPAISQTTNYIHQHQF
HHHHHHHHHHHCCEECCEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
DYDYVDSTIQSLTKIENGVAAIAPLGSGEAYGFTPIDTHIEDYPHNVTRFLVIKNQQQFD
CHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCHHCCCCCEEEEEEEECHHHHC
QNATSLMFLITPMHDKPGLLASVLNTFALFNINLSWIESRPLKTQLGMYRFFVQADSAIT
CCCCEEEEEEECCCCCCCHHHHHHHHHHEEEEEEEEECCCCCHHHHHHEEEEEECCCHHH
TDIKKVIAILETLDFKVEMIGAFN
HHHHHHHHHHHHHCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]